#microglia — Public Fediverse posts

Brain immune cells found to regulate anxiety and grooming behaviors

A study led by a University of Louisville School of Medicine pediatrics and child neurology researcher reveals how…
#NewsBeep #News #Health #Anxiety #AU #Australia #autism #Brain #Calcium #Cell #Chronic #Gene #medicine #Microglia #Neurology #pediatrics #Physiology #psychiatry #research
https://www.newsbeep.com/au/670933/

Brain immune cells found to regulate anxiety and grooming behaviors

A study led by a University of Louisville School of Medicine pediatrics and child neurology researcher reveals how…
#NewsBeep #News #Health #Anxiety #AU #Australia #autism #Brain #Calcium #Cell #Chronic #Gene #medicine #Microglia #Neurology #pediatrics #Physiology #psychiatry #research
https://www.newsbeep.com/au/670933/

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

🧠 Alzheimer's & Microglia - Apr 2026

• Somatic cancer variants in microglia may drive Alzheimer's inflammation
• PAD2 in astrocytes worsens amyloid pathology via microglial activation
• Microglia uptake and release tau aggregates, seeding neuronal spread
• CK2 inhibition reduces glial inflammation and improves cognition

https://pir.sh/rk9156mdnp

#Alzheimer #Microglia #Biology

https://www.europesays.com/ie/447562/ Calcium signals in microglia drive anxiety and compulsive behaviors #anxiety #Brain #Calcium #Chronic #Éire #Genetic #Genetics #IE #Ireland #medicine #microglia #Microscope #MouseModel #Neurons #Physiology #Psychiatry #Research #Science

Loss of Smell Linked to Early Alzheimer’s Immune Activity

📰 Original title: Your nose could detect Alzheimer’s years before symptoms begin

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/loss-of-smell-linked-to-early-alzheimers-immune-activity/?redirpost=5c3024a3-e4fe-4f6b-bcf5-2a9dd2d2ae35

#neuroscience #alzheimer's #smell #microglia

Enriched environments improve stroke recovery and reduce brain inflammation

Stroke is one of the leading causes of death worldwide. Its recovery is often challenging as most of…
#Environment #brain #Chronic #disability #Inflammation #microglia #Myelin #Q #research #Stroke
https://www.europesays.com/2913948/

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

RE: https://fediscience.org/@eLife/116238133569931871

In mice, but very interesting. A commentary on the research paper:

"Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi–Goutières syndrome neuropathology", Nemec et al. 2026
https://elifesciences.org/articles/102900

#neuroscience #microglia #mice #neuropathology

https://www.europesays.com/es/446824/ El CNIO revela que el inicio de la pubertad depende también del sistema inmunitario del cerebro – Servimedia #CNIO #ES #España #Fertilidad #Health #microglía #pubertad #Salud #Sociedad #Spain

🧫 Microglia - Feb 2026

• IL-10 variant boosts neurogenesis and cognition in aged mice
• RIPK1 inhibition blocks pro-inflammatory drivers of Alzheimer
• BTK inhibition reduces neuroinflammation in ALS models
• Distinct epigenomic subtypes reveal unique microglial signatures in Alzheimer's
• Microglia-T cell interactions drive neurodegeneration in Huntington's
• TGF-β inhibition in microglia stimulates adult neurogenesis

https://pir.sh/JoZa0Nr1Gy

#Microglia #Neuroinflammation #Neurodegeneration

Investigating microglia’s role in Alzheimer’s pathology

Announcing a new article publication for BIO Integration journal. Alzheimer’s disease (AD) is a neurodegenerative disorder and the…
#NewsBeep #News #Health #Agonist #Alzheimer'sdisease #Antibody #Brain #CA #Canada #Cell #CentralNervousSystem #Dementia #language #Ligand #Microglia #MonoclonalAntibody #nervoussystem #neurodegenerativedisorder #Pathology #Receptor #RNA #RNAsequencing #Transcriptomics
https://www.newsbeep.com/ca/508841/

https://www.europesays.com/ie/363426/ Investigating microglia’s role in Alzheimer’s pathology #Agonist #Alzheimer'sDisease #Antibody #Brain #Cell #CentralNervousSystem #dementia #Éire #Health #IE #Ireland #Language #Ligand #microglia #MonoclonalAntibody #NervousSystem #NeurodegenerativeDisorder #Pathology #Receptor #RNA #RNASequencing #Transcriptomics

https://www.europesays.com/ie/348367/ Grant supports research into how microglia may spread toxic tau in Alzheimer’s #Alzheimer'sDisease #Brain #Cell #Éire #Health #IE #Ireland #Lysosomes #microglia #NeurodegenerativeDiseases #Neurons #Nursing #Pathology #Pharmacology #Protein #Receptor #Research #Stress #TauProtein #website

🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Microglia — Jan 2026

• TREM2 and metabolic rewiring influence neurodegeneration
• Infectious and inflammatory triggers amplify CNS immune signaling
• Microglia-targeted therapies gain momentum in neurodegenerative disease

https://pir.sh/qmxdxQyayp

#Microglia #Neuroinflammation #Neurodegeneration

https://www.europesays.com/ie/295199/ Suppressing brain immune cells enhances memory recall in young mice #Amnesia #Amygdala #Brain #Cell #children #Éire #Health #Hippocampus #IE #Ireland #microglia #Research

https://www.europesays.com/ie/288877/ Study reveals how ketogenic diet protects against epilepsy seizures #Brain #diet #Drugs #Éire #Epilepsy #Health #IE #Ireland #KetogenicDiet #medicine #microglia #NeurodegenerativeDiseases #neurology #Neurons #Niacin #Receptor #Research

Brain immune cells drive persistent negative emotions after repeated binge drinking

New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying…
#NewsBeep #News #Health #Abstinence #Alcohol #Anxiety #AU #Australia #BingeDrinking #Brain #Chronic #Cortex #depression #Ethanol #Mentalhealth #Microglia #Pathology #protein #research
https://www.newsbeep.com/au/409553/

Brain immune cells drive persistent negative emotions after repeated binge drinking

New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying…
#NewsBeep #News #Health #Abstinence #Alcohol #anxiety #BingeDrinking #Brain #CA #Canada #Chronic #Cortex #depression #Ethanol #Mentalhealth #Microglia #Pathology #Protein #research
https://www.newsbeep.com/ca/405897/

https://www.europesays.com/ie/281673/ Brain immune cells drive persistent negative emotions after repeated binge drinking #Abstinence #Alcohol #anxiety #BingeDrinking #Brain #Chronic #Cortex #Depression #Éire #Ethanol #Health #IE #Ireland #MentalHealth #microglia #Pathology #Protein #Research

Happy to announce that our #JOSS paper on #MotilA is now published 😊

MotilA is an #OpenSource #Python pipeline for quantifying microglial fine-process motility in 3D/4D in vivo multiphoton #imaging data. It is specifically designed for reproducible, batch-scale analysis.

The paper describes the methodology, implementation, and scope of the software:

📄 https://doi.org/10.21105/joss.09267
💻 https://github.com/FabrizioMusacchio/MotilA
📘 https://motila.readthedocs.io/

#Neuroscience #Microglia #OpenScience #FOSS

Happy to announce that our #JOSS paper on #MotilA is now published 😊

MotilA is an #OpenSource #Python pipeline for quantifying microglial fine-process motility in 3D/4D in vivo multiphoton #imaging data. It is specifically designed for reproducible, batch-scale analysis.

The paper describes the methodology, implementation, and scope of the software:

📄 https://doi.org/10.21105/joss.09267
💻 https://github.com/FabrizioMusacchio/MotilA
📘 https://motila.readthedocs.io/

#Neuroscience #Microglia #OpenScience #FOSS