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#microglia — Public Fediverse posts

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  1. DATE: August 14, 2026 at 09:28AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: Immune cells flood into the aging brain, Stanford scientists discover

    URL: sciencedaily.com/releases/2026

    Scientists have discovered that the aging human brain may be far less isolated from the rest of the body than once believed. Stanford researchers found that large numbers of immune cells from the blood begin entering the brain as early as middle age, where they can transform into microglia, the brain’s specialized immune cells. The finding overturns a long-standing assumption that these cells remain largely separate from the body’s immune system throughout life.

    URL: sciencedaily.com/releases/2026

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    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AgingBrain #ImmuneCells #Microglia #StanfordResearch #Neuroscience #BrainHealth #Immunology #MiddleAge #Neuroinflammation # BrainBodyConnection

  2. 🚀 #MotilA now runs with #OMIO!

    Today’s version release v1.1.2 adds much more flexible image I/O: #TIFF/ OME-TIFF, #CZI, #LSM & #Thorlabs RAW are now read via OMIO and normalized to #OME-compliant TZCYX axis-order, automatically. So, no more manual axis reordering before analysis 🤗

    🌍 motila.readthedocs.io/en/lates

    #microglia #motility #Bioimageanalysis #Python

  3. Alzheimer's breakthrough: Scientists restore two hours of sleep without clearing brain plaques

    Like and share if you enjoyed this.

    1ban.news/microglia-sleep-loss

    #1ban #microglia #sleep #loss #alzheimers #neuroscience

  4. A recent visit to the #YayoiKusama exhibition at the #MuseumLudwig in #Cologne proved that I’m already very neuro-biased: In many of her paintings, I see nothing but … #dendrites and #spines, #microglia, cell membranes… 🙈😅

  5. Relevant for brain implants? Frequency-specific effects of pulsed magnetic field on BV2 microglial cell function tandfonline.com/doi/full/10.10 "pulsed magnetic field can effectively regulate microglial phagocytosis, migration, and inflammatory cytokine secretion"; #rTMS #microglia #BCI #neuroscience

  6. What are the mechanisms allowing #zebrafish to #regenerate their neurons after spinal cord injury? This study by Alberto Docampo-Seara, Catherine Becker, Thomas Becker &co shows that a protein in #microglia regulates regenerative #neurogenesis in multiple ways

    plos.io/4xy2CcB

  7. 🧠🚓 New paper on #microglia depletion: #CSF1R inhibition with #PLX5622 is not microglia-specific, it also depletes long-lived peripheral #macrophage populations. Could become important for interpreting #microglial #depletion experiments: Phenotypes after depletion or recovery may reflect broader macrophage niche perturbation, not microglia alone:

    📄 doi.org/10.1016/j.celrep.2026.

    #Neuroscience #Neuroimmunology

  8. Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

    #glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

  9. 🧠 Alzheimer's & Microglia - Apr 2026

    • Somatic cancer variants in microglia may drive Alzheimer's inflammation
    • PAD2 in astrocytes worsens amyloid pathology via microglial activation
    • Microglia uptake and release tau aggregates, seeding neuronal spread
    • CK2 inhibition reduces glial inflammation and improves cognition

    pir.sh/rk9156mdnp

    #Alzheimer #Microglia #Biology

  10. Loss of Smell Linked to Early Alzheimer’s Immune Activity

    📰 Original title: Your nose could detect Alzheimer’s years before symptoms begin

    🤖 IA: It's not clickbait ✅
    👥 Usuarios: It's not clickbait ✅

    View full AI summary: killbait.com/en/loss-of-smell-

    #neuroscience #alzheimer's #smell #microglia

  11. @MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

    Huge congrats to Felix and all co-authors! 🥳

    @dzne #DZNE

  12. 🧠 New paper from the @MaFu55 lab! 🥳

    Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

    📝 doi.org/10.1016/j.immuni.2026.

    #Neuroscience 🧪 @dzne #3P

  13. 🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

    📝 doi.org/10.1016/j.celrep.2026.

    #Neuroscience 🧪 #2pImaging

  14. @dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

    #Microglial Ca-dynamics (Eyberg, A44)
    NE-modulated #microglia (Antony, A45)
    #Stress-driven #synapse remodeling (Crux, A46)
    #Actin control of microglia (Hoffmann, A47)
    #Odor coding in #SNNs (myself, A11)

    Stop by our posters today 👌

  15. RE: fediscience.org/@eLife/1162381

    In mice, but very interesting. A commentary on the research paper:

    "Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi–Goutières syndrome neuropathology", Nemec et al. 2026
    elifesciences.org/articles/102

    #neuroscience #microglia #mice #neuropathology

  16. 🧠 Alzheimer Microglia — Jan 2026

    • Distinct microglial states emerge with disease-specific gene programs
    • TREM2 and metabolic wiring shape microglial function in AD
    • Environmental and infectious signals modulate neuroinflammation
    • Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

    pir.sh/z0odQxl1LO

    #Alzheimers #Microglia #Neuroinflammation #Neuroscience

  17. Happy to announce that our #JOSS paper on #MotilA is now published 😊

    MotilA is an #OpenSource #Python pipeline for quantifying microglial fine-process motility in 3D/4D in vivo multiphoton #imaging data. It is specifically designed for reproducible, batch-scale analysis.

    The paper describes the methodology, implementation, and scope of the software:

    📄 doi.org/10.21105/joss.09267
    💻 github.com/FabrizioMusacchio/M
    📘 motila.readthedocs.io/

    #Neuroscience #Microglia #OpenScience #FOSS

  18. Disease-associated #microglia are a distinct state associated with #AlzheimersDisease, #ALS & #aging. This Essay explores the dynamics, origins & therapeutic potential of these microglia in #neurodegeneration, alongside evidence supporting a protective role @PLOSBiology plos.io/49mmzcm

  19. What's the role of microglial chromatin-mediated processes? This study shows that loss of ATRX in #microglia disrupts #chromatin structure, leading to de-repression of #retroelements & a viral mimicry #inflammation response that impairs hippocampal neuron function @PLOSBiology plos.io/46cBaE4