#microglia — Public Fediverse posts

Interestingly, #Virchow also introduced the concept of #neuroglia as a distinct #cellular component of the #NervousSystem. This was a crucial step in understanding the cellular composition of the nervous system and laid the groundwork for later #neuroscience research on glial cells.

#glia #GliaCells #Astrocytes #Oligodendrocytes #Microglia #NeuroscienceHistory

Loss of Smell Linked to Early Alzheimer’s Immune Activity

📰 Original title: Your nose could detect Alzheimer’s years before symptoms begin

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/loss-of-smell-linked-to-early-alzheimers-immune-activity/?redirpost=5c3024a3-e4fe-4f6b-bcf5-2a9dd2d2ae35

#neuroscience #alzheimer's #smell #microglia

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

@dzne The @MaFu55 Lab (#DZNE) at #BonnBrain26:

#Microglial Ca-dynamics (Eyberg, A44)
NE-modulated #microglia (Antony, A45)
#Stress-driven #synapse remodeling (Crux, A46)
#Actin control of microglia (Hoffmann, A47)
#Odor coding in #SNNs (myself, A11)

Stop by our posters today 👌

Understanding Brain Trauma: Cellular Responses and Molecular Cascades

#BrainInjury #Neuroinflammation #TraumaticBrainInjury #Microglia #Astrocytes #BloodBrainBarrier #Neuroregeneration #BrainHealth #Neuroscience #BrainRecovery

https://youtube.com/shorts/HyozNFxpwxg?feature=share

When Brain Balance Tips: Understanding Neuroinflammation After Head Injuries

#BrainHealth #Microglia #Neuroinflammation #Neurodegeneration #Alzheimers #Parkinsons #BrainScience #Neuroscience #BrainAging #Neurobiology #ProteinAggregates #BrainRepair #Neuroimmunology #BrainCells #CognitiveHealth

https://youtube.com/shorts/SwQyfeFs4jg?feature=share

Neurons, Glia, and Blood Vessels: The Complex City of the Brain

#BrainHealth #Neuroscience #AlzheimersDisease #Neuroinflammation #Microglia #CognitiveHealth #Neurodegeneration #BrainResearch #NeurotrophicFactors #HealthyBrain #MindAndMemory #BrainScience #NeuralNetworks #BrainCare #Neuroprotection

https://youtube.com/shorts/BrgBN5EzQHM?feature=share

Balancing Act: How Neurotransmitters and Endocannabinoids Maintain Brain Health

#BrainScience #Neuroscience #EndocannabinoidSystem #Neuroimmune #BrainHealth #Neurotransmitters #Microglia #Neuroinflammation #MentalHealth #NeuroscienceEducation #BrainFunction #NeuroProtection #LearnAboutTheBrain #BrainJourney

https://youtube.com/shorts/zLAkRjtxiU8?feature=share

Balancing Act: How Neurotransmitters and Endocannabinoids Maintain Brain Health

#BrainScience #Neuroscience #EndocannabinoidSystem #Neuroimmune #BrainHealth #Neurotransmitters #Microglia #Neuroinflammation #MentalHealth #NeuroscienceEducation #BrainFunction #NeuroProtection #LearnAboutTheBrain #BrainJourney

https://youtube.com/shorts/zLAkRjtxiU8?feature=share

Balancing Act: How Neurotransmitters and Endocannabinoids Maintain Brain Health

#BrainScience #Neuroscience #EndocannabinoidSystem #Neuroimmune #BrainHealth #Neurotransmitters #Microglia #Neuroinflammation #MentalHealth #NeuroscienceEducation #BrainFunction #NeuroProtection #LearnAboutTheBrain #BrainJourney

https://youtube.com/shorts/zLAkRjtxiU8?feature=share

Balancing Act: How Neurotransmitters and Endocannabinoids Maintain Brain Health

#BrainScience #Neuroscience #EndocannabinoidSystem #Neuroimmune #BrainHealth #Neurotransmitters #Microglia #Neuroinflammation #MentalHealth #NeuroscienceEducation #BrainFunction #NeuroProtection #LearnAboutTheBrain #BrainJourney

https://youtube.com/shorts/zLAkRjtxiU8?feature=share

Balancing Act: How Neurotransmitters and Endocannabinoids Maintain Brain Health

#BrainScience #Neuroscience #EndocannabinoidSystem #Neuroimmune #BrainHealth #Neurotransmitters #Microglia #Neuroinflammation #MentalHealth #NeuroscienceEducation #BrainFunction #NeuroProtection #LearnAboutTheBrain #BrainJourney

https://youtube.com/shorts/zLAkRjtxiU8?feature=share

Exploring the Brain: A Journey Through Neuroimaging and Neural Dynamics

#BrainScience #Neuroimaging #Neuroscience #BrainHealth #Microglia #Synapses #Endocannabinoid #Neurochemistry #BrainArchitecture #Memory #Cognition #MoodRegulation #Neurotherapy #BrainConnectivity #MentalHealth #NeuroscienceExplained

https://youtube.com/shorts/JBEXN3VIQ5I?feature=share

News to me: Local translation isn't limited to neurons, apparently also happens in glial processes. See here for #microglia:

Local translation in microglial processes is required for efficient phagocytosis
Vasek et al., Nature Neuroscience 2023
https://doi.org/10.1038/s41593-023-01353-0

The accompanying news & views write-up has a useful overview figure: https://doi.org/10.1038/s41593-023-01370-z

#neuroscience #glia #proteintranslation

'For example, loss of function of the microglial gene Trem2 renders microglia dysfunctional and causes an early-onset neurodegenerative syndrome, and Trem2 variants are among the strongest genetic risk factors for AD. Thus, restoring microglial function represents a rational therapeutic approach. Here, we show that systemic hematopoietic cell transplantation followed by enhancement of microglia replacement restores microglial function in a Trem2 mutant mouse model of AD.'

#Alzheimer #NeurodegenerativeDisease #Microglia #Neuroimmunology

https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00251-5#%20

Want to explore deep brain 🧠🔬 #threephoton imaging of #glioma and #microglia dynamics in the #corpuscallosum? Don't miss Felix Nebeling's (@FelixNeb) poster T24-021B at the #gliameeting in #Berlin today 💪
@dzne #GLIA2023 #3p

Severe infection may raise odds of autism in some children

https://www.spectrumnews.org/news/severe-infection-may-raise-odds-of-autism-in-some-children/

#tuberoussclerosis #immunesystem #environment #microglia #autism #News #TSC2