home.social

#drugrepurposing — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #drugrepurposing, aggregated by home.social.

fetched live
  1. UH College of Pharmacy secures funding for three major health studies

    University of Houston College of Pharmacy researchers have secured more than $1 million in new funding to support…
    #NewsBeep #News #Health #Alzheimer'sDisease #AU #Australia #Cell #Dementia #depression #drugrepurposing #Drugs #Healthcare #Hospital #Nanomedicine #Nanoparticle #Pharmacy #Preclinical #research #sepsis #SickleCellDisease
    newsbeep.com/au/851862/

  2. DATE: June 16, 2026 at 02:48AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: Copper drug clears toxic Alzheimer’s proteins and restores memory

    URL: sciencedaily.com/releases/2026

    A copper-based compound restored the brain’s ability to clear toxic Alzheimer’s proteins, dramatically reducing amyloid buildup and improving memory in laboratory experiments. The findings point to a potentially fast-tracked new treatment strategy because the drug has already been tested in humans for other neurological conditions.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CopperDrug #AlzheimersResearch #MemoryRestoration #AmyloidClearing #NeurodegenerativeTherapy #CopperBasedTherapy #BrainHealth #DrugRepurposing #NeurologyNews #CognitiveImprovement

  3. DATE: June 16, 2026 at 02:48AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: Copper drug clears toxic Alzheimer’s proteins and restores memory

    URL: sciencedaily.com/releases/2026

    A copper-based compound restored the brain’s ability to clear toxic Alzheimer’s proteins, dramatically reducing amyloid buildup and improving memory in laboratory experiments. The findings point to a potentially fast-tracked new treatment strategy because the drug has already been tested in humans for other neurological conditions.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CopperDrug #AlzheimersResearch #MemoryRestoration #AmyloidClearing #NeurodegenerativeTherapy #CopperBasedTherapy #BrainHealth #DrugRepurposing #NeurologyNews #CognitiveImprovement

  4. DATE: June 16, 2026 at 02:48AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: Copper drug clears toxic Alzheimer’s proteins and restores memory

    URL: sciencedaily.com/releases/2026

    A copper-based compound restored the brain’s ability to clear toxic Alzheimer’s proteins, dramatically reducing amyloid buildup and improving memory in laboratory experiments. The findings point to a potentially fast-tracked new treatment strategy because the drug has already been tested in humans for other neurological conditions.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CopperDrug #AlzheimersResearch #MemoryRestoration #AmyloidClearing #NeurodegenerativeTherapy #CopperBasedTherapy #BrainHealth #DrugRepurposing #NeurologyNews #CognitiveImprovement

  5. It's interesting that they paired a talk on ergothioneine, which is primarily thought of as an anti-oxidant (though as discussed in the video, there may be more to its MOA) with hemin, which is a potent pro-oxidant.

    There was an in vitro study that suggested hemin might be useful in acute Covid, but it never went anywhere AFAIK. The paper is still interesting for background on hemin as an HO-1 inducer -
    pmc.ncbi.nlm.nih.gov/articles/

    #hemin #HemeOxygenase #DrugRepurposing

  6. It's interesting that they paired a talk on ergothioneine, which is primarily thought of as an anti-oxidant (though as discussed in the video, there may be more to its MOA) with hemin, which is a potent pro-oxidant.

    There was an in vitro study that suggested hemin might be useful in acute Covid, but it never went anywhere AFAIK. The paper is still interesting for background on hemin as an HO-1 inducer -
    pmc.ncbi.nlm.nih.gov/articles/

    #hemin #HemeOxygenase #DrugRepurposing

  7. It's interesting that they paired a talk on ergothioneine, which is primarily thought of as an anti-oxidant (though as discussed in the video, there may be more to its MOA) with hemin, which is a potent pro-oxidant.

    There was an in vitro study that suggested hemin might be useful in acute Covid, but it never went anywhere AFAIK. The paper is still interesting for background on hemin as an HO-1 inducer -
    pmc.ncbi.nlm.nih.gov/articles/

    #hemin #HemeOxygenase #DrugRepurposing

  8. It's interesting that they paired a talk on ergothioneine, which is primarily thought of as an anti-oxidant (though as discussed in the video, there may be more to its MOA) with hemin, which is a potent pro-oxidant.

    There was an in vitro study that suggested hemin might be useful in acute Covid, but it never went anywhere AFAIK. The paper is still interesting for background on hemin as an HO-1 inducer -
    pmc.ncbi.nlm.nih.gov/articles/

    #hemin #HemeOxygenase #DrugRepurposing

  9. Erythromycin has therapeutic efficacy on muscle fatigue acting specifically on orosomucoid to increase muscle bioenergetics and physiological parameters of endurance [2020]

    abstract:
    pubmed.ncbi.nlm.nih.gov/327772

    preprint can be downloaded here:
    papers.ssrn.com/sol3/papers.cf

    #orosomucoid #fatigue #erythromycin #DrugRepurposing #DrugDevelopment

  10. Erythromycin has therapeutic efficacy on muscle fatigue acting specifically on orosomucoid to increase muscle bioenergetics and physiological parameters of endurance [2020]

    abstract:
    pubmed.ncbi.nlm.nih.gov/327772

    preprint can be downloaded here:
    papers.ssrn.com/sol3/papers.cf

    #orosomucoid #fatigue #erythromycin #DrugRepurposing #DrugDevelopment

  11. Erythromycin has therapeutic efficacy on muscle fatigue acting specifically on orosomucoid to increase muscle bioenergetics and physiological parameters of endurance [2020]

    abstract:
    pubmed.ncbi.nlm.nih.gov/327772

    preprint can be downloaded here:
    papers.ssrn.com/sol3/papers.cf

    #orosomucoid #fatigue #erythromycin #DrugRepurposing #DrugDevelopment

  12. Erythromycin has therapeutic efficacy on muscle fatigue acting specifically on orosomucoid to increase muscle bioenergetics and physiological parameters of endurance [2020]

    abstract:
    pubmed.ncbi.nlm.nih.gov/327772

    preprint can be downloaded here:
    papers.ssrn.com/sol3/papers.cf

    #orosomucoid #fatigue #erythromycin #DrugRepurposing #DrugDevelopment

  13. Một dự án mới sử dụng AI kết hợp đồ tri thức để tái định vị công dụng của thuốc. Công cụ này giúp nhà nghiên cứu tìm ra thuốc cũ có thể trị bệnh mới, đồng thời hiển thị các bước luận giải một cách minh bạch. Dự án vẫn ở giai đoạn thử nghiệm.

    #AI #DrugRepurposing #SideProject #HealthTech #Research #YKhoa #DuAnPhu #CongNgheSucKhoe #NghienCuu

    reddit.com/r/SideProject/comme

  14. 🚀 Dự án phụ: công cụ khám phá tái sử dụng thuốc dựa trên AI giải thích được. Kết hợp knowledge graph và XAI để xếp hạng cặp thuốc‑bệnh, hiển thị đường dẫn lý luận (thuốc → mục tiêu → đường truyền → bệnh). Xây dựng bằng Python + React, hiện dùng dữ liệu mô phỏng. Mong nhận phản hồi về tính hữu ích, dữ liệu thực và cải tiến. #AI #DrugRepurposing #Research #SideProject #CôngNghệ #YHọc

    reddit.com/r/SideProject/comme

  15. Van Andel Institute and Cure Parkinson’s extend major Parkinson’s drug trial initiative

    Van Andel Institute and Cure Parkinson’s have renewed a funding agreement to support the International Linked Clinical Trials…
    #NewsBeep #News #Health #AU #Australia #clinicaltrial #drugrepurposing #Drugs #nextgeneration #Parkinson’sdisease #pH #research
    newsbeep.com/au/340071/

  16. Brayden Yellman, MD | Underappreciated Co-Morbidities in ME/CFS
    video uploaded Oct. 16, 2025
    youtu.be/od0epKW19og

    [13:03] hydroxyurea used to treat a person with POTS and MCAS

    Here's an article on the topic:

    Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series [2022]
    pmc.ncbi.nlm.nih.gov/articles/

    "First used 60 years ago for chronic myeloproliferative neoplasms, HU is now standard of care in reducing the severity of sickle cell disease (SCD) (McGann and Ware 2015). In this context, it is of interest that in animal models and human subjects with SCD, medications that reduce MC activation decreased bone pain (Vincent et al. 2013, 2016). HU also inhibits replication of human immunodeficiency virus-1 (HIV-1) and has been used in therapy of cyanotic congenital heart disease (Lori and Lisziewicz 2000; Reiss et al. 2007). A theoretic explanation for effectiveness of HU in these diseases include reducing MC activity independent of anti-proliferative effects. HU could decrease activity and ability of GI mucosal MCs that capture HIV-1 and mediate trans-infection of CD4 + T cells (Jiang et al. 2015). Similarly, HU could reduce the activity of the increased numbers of chymase-containing MCs in lung tissue of congenital heart disease patients and, thereby, decrease severity of these pulmonary and cardiac diseases (Hamada et al. 1999)."

    The mechanisms are probably quite complex. One facet is that hydroxyurea increases fetal hemoglobin production and RBC membrane flexibility - which could increase O2 perfusion. Hypoxia activates mast cells.

    #MECFS #MCAS #POTS #DrugRepurposing #hydroxyurea #MastCells #immunology

  17. Brayden Yellman, MD | Underappreciated Co-Morbidities in ME/CFS
    video uploaded Oct. 16, 2025
    youtu.be/od0epKW19og

    [13:03] hydroxyurea used to treat a person with POTS and MCAS

    Here's an article on the topic:

    Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series [2022]
    pmc.ncbi.nlm.nih.gov/articles/

    "First used 60 years ago for chronic myeloproliferative neoplasms, HU is now standard of care in reducing the severity of sickle cell disease (SCD) (McGann and Ware 2015). In this context, it is of interest that in animal models and human subjects with SCD, medications that reduce MC activation decreased bone pain (Vincent et al. 2013, 2016). HU also inhibits replication of human immunodeficiency virus-1 (HIV-1) and has been used in therapy of cyanotic congenital heart disease (Lori and Lisziewicz 2000; Reiss et al. 2007). A theoretic explanation for effectiveness of HU in these diseases include reducing MC activity independent of anti-proliferative effects. HU could decrease activity and ability of GI mucosal MCs that capture HIV-1 and mediate trans-infection of CD4 + T cells (Jiang et al. 2015). Similarly, HU could reduce the activity of the increased numbers of chymase-containing MCs in lung tissue of congenital heart disease patients and, thereby, decrease severity of these pulmonary and cardiac diseases (Hamada et al. 1999)."

    The mechanisms are probably quite complex. One facet is that hydroxyurea increases fetal hemoglobin production and RBC membrane flexibility - which could increase O2 perfusion. Hypoxia activates mast cells.

    #MECFS #MCAS #POTS #DrugRepurposing #hydroxyurea #MastCells #immunology

  18. Brayden Yellman, MD | Underappreciated Co-Morbidities in ME/CFS
    video uploaded Oct. 16, 2025
    youtu.be/od0epKW19og

    [13:03] hydroxyurea used to treat a person with POTS and MCAS

    Here's an article on the topic:

    Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series [2022]
    pmc.ncbi.nlm.nih.gov/articles/

    "First used 60 years ago for chronic myeloproliferative neoplasms, HU is now standard of care in reducing the severity of sickle cell disease (SCD) (McGann and Ware 2015). In this context, it is of interest that in animal models and human subjects with SCD, medications that reduce MC activation decreased bone pain (Vincent et al. 2013, 2016). HU also inhibits replication of human immunodeficiency virus-1 (HIV-1) and has been used in therapy of cyanotic congenital heart disease (Lori and Lisziewicz 2000; Reiss et al. 2007). A theoretic explanation for effectiveness of HU in these diseases include reducing MC activity independent of anti-proliferative effects. HU could decrease activity and ability of GI mucosal MCs that capture HIV-1 and mediate trans-infection of CD4 + T cells (Jiang et al. 2015). Similarly, HU could reduce the activity of the increased numbers of chymase-containing MCs in lung tissue of congenital heart disease patients and, thereby, decrease severity of these pulmonary and cardiac diseases (Hamada et al. 1999)."

    The mechanisms are probably quite complex. One facet is that hydroxyurea increases fetal hemoglobin production and RBC membrane flexibility - which could increase O2 perfusion. Hypoxia activates mast cells.

    #MECFS #MCAS #POTS #DrugRepurposing #hydroxyurea #MastCells #immunology

  19. Brayden Yellman, MD | Underappreciated Co-Morbidities in ME/CFS
    video uploaded Oct. 16, 2025
    youtu.be/od0epKW19og

    [13:03] hydroxyurea used to treat a person with POTS and MCAS

    Here's an article on the topic:

    Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series [2022]
    pmc.ncbi.nlm.nih.gov/articles/

    "First used 60 years ago for chronic myeloproliferative neoplasms, HU is now standard of care in reducing the severity of sickle cell disease (SCD) (McGann and Ware 2015). In this context, it is of interest that in animal models and human subjects with SCD, medications that reduce MC activation decreased bone pain (Vincent et al. 2013, 2016). HU also inhibits replication of human immunodeficiency virus-1 (HIV-1) and has been used in therapy of cyanotic congenital heart disease (Lori and Lisziewicz 2000; Reiss et al. 2007). A theoretic explanation for effectiveness of HU in these diseases include reducing MC activity independent of anti-proliferative effects. HU could decrease activity and ability of GI mucosal MCs that capture HIV-1 and mediate trans-infection of CD4 + T cells (Jiang et al. 2015). Similarly, HU could reduce the activity of the increased numbers of chymase-containing MCs in lung tissue of congenital heart disease patients and, thereby, decrease severity of these pulmonary and cardiac diseases (Hamada et al. 1999)."

    The mechanisms are probably quite complex. One facet is that hydroxyurea increases fetal hemoglobin production and RBC membrane flexibility - which could increase O2 perfusion. Hypoxia activates mast cells.

    #MECFS #MCAS #POTS #DrugRepurposing #hydroxyurea #MastCells #immunology

  20. 💊 New in #DrugRepurposing Journal (Vol. 2, Issue 1):

    "Role of Chemoinformatics & Machine Learning in Drug Repurposing"

    From virtual screening & molecular docking to AI & AlphaFold — computational tools are transforming how we find new uses for old drugs.

    #AI #MachineLearning #DrugDiscovery

  21. 💊 New in #DrugRepurposing Journal (Vol. 2, Issue 1):

    "Role of Chemoinformatics & Machine Learning in Drug Repurposing"

    From virtual screening & molecular docking to AI & AlphaFold — computational tools are transforming how we find new uses for old drugs.

    #AI #MachineLearning #DrugDiscovery

  22. 💊 New in #DrugRepurposing Journal (Vol. 2, Issue 1):

    "Role of Chemoinformatics & Machine Learning in Drug Repurposing"

    From virtual screening & molecular docking to AI & AlphaFold — computational tools are transforming how we find new uses for old drugs.

    #AI #MachineLearning #DrugDiscovery

  23. 📖 💊 New Issue Alert!

    Drug Repurposing Vol 2, Issue 1 is out! 5 exciting articles explore AI, chemoinformatics, VR collaboration, and more — showing how existing drugs can find new therapeutic uses.

    #DrugRepurposing #OpenScience #DrugDiscovery

  24. 📖 💊 New Issue Alert!

    Drug Repurposing Vol 2, Issue 1 is out! 5 exciting articles explore AI, chemoinformatics, VR collaboration, and more — showing how existing drugs can find new therapeutic uses.

    #DrugRepurposing #OpenScience #DrugDiscovery

  25. 📖 💊 New Issue Alert!

    Drug Repurposing Vol 2, Issue 1 is out! 5 exciting articles explore AI, chemoinformatics, VR collaboration, and more — showing how existing drugs can find new therapeutic uses.

    #DrugRepurposing #OpenScience #DrugDiscovery

  26. 📖 💊 New Issue Alert!

    Drug Repurposing Vol 2, Issue 1 is out! 5 exciting articles explore AI, chemoinformatics, VR collaboration, and more — showing how existing drugs can find new therapeutic uses.

    #DrugRepurposing #OpenScience #DrugDiscovery

  27. A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
    pubs.acs.org/doi/full/10.1021/

    lots of details on #pathophysiology in this review

    #MECFS #LongCovid #metformin #DrugRepurposing #medicine #health
    #WASF3

  28. A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
    pubs.acs.org/doi/full/10.1021/

    lots of details on #pathophysiology in this review

    #MECFS #LongCovid #metformin #DrugRepurposing #medicine #health
    #WASF3

  29. A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
    pubs.acs.org/doi/full/10.1021/

    lots of details on #pathophysiology in this review

    #MECFS #LongCovid #metformin #DrugRepurposing #medicine #health
    #WASF3

  30. A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
    pubs.acs.org/doi/full/10.1021/

    lots of details on #pathophysiology in this review

    #MECFS #LongCovid #metformin #DrugRepurposing #medicine #health
    #WASF3