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#nucleotide — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #nucleotide, aggregated by home.social.

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  1. Statins may trigger muscle side effects by activating inflammatory danger signals

    New experimental findings reveal how statins may push vulnerable muscle cells into a stress state, suggesting future strategies…
    #NewsBeep #News #Technology #AU #Australia #Cell #cholesterol #Glycolysis #Healthcare #Heart #Inflammasome #Leucine #Lipoprotein #Muscle #muscleatrophy #Nucleotide #protein #Statin #stress #therapy
    newsbeep.com/au/754336/

  2. Statins may trigger muscle side effects by activating inflammatory danger signals

    New experimental findings reveal how statins may push vulnerable muscle cells into a stress state, suggesting future strategies…
    #NewsBeep #News #Technology #AU #Australia #Cell #cholesterol #Glycolysis #Healthcare #Heart #Inflammasome #Leucine #Lipoprotein #Muscle #muscleatrophy #Nucleotide #protein #Statin #stress #therapy
    newsbeep.com/au/754336/

  3. Microbial genetic variation shapes neurocognitive behavior in sheep

    The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota,…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Animalmodel #Brain #Genetic #Metabolism #Metabolites #Microbiome #Nucleotide #Phenotype #Science
    newsbeep.com/us/216171/

  4. Microbial genetic variation shapes neurocognitive behavior in sheep

    The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota,…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Animalmodel #Brain #Genetic #Metabolism #Metabolites #Microbiome #Nucleotide #Phenotype #Science
    newsbeep.com/us/216171/

  5. Microbial genetic variation shapes neurocognitive behavior in sheep

    The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota,…
    #NewsBeep #News #Genetics #AnimalModel #Brain #Genetic #Metabolism #Metabolites #Microbiome #Nucleotide #Phenotype #Science #UK #UnitedKingdom
    newsbeep.com/uk/192195/

  6. #Evolution and mutational #landscape of highly pathogenic avian #influenza strain A(#H5N1) in current #outbreak in #USA & global landscape, Virology: sciencedirect.com/science/arti

    The study evaluated the virus evolution, divergence, #transmission #patterns, and infection patterns. The study also illustrated entropy diversity in the #genome, #nucleotide diversity in the genome, and mutational landscape.

  7. #Evolution and mutational #landscape of highly pathogenic avian #influenza strain A(#H5N1) in current #outbreak in #USA & global landscape, Virology: sciencedirect.com/science/arti

    The study evaluated the virus evolution, divergence, #transmission #patterns, and infection patterns. The study also illustrated entropy diversity in the #genome, #nucleotide diversity in the genome, and mutational landscape.

  8. #Evolution and mutational #landscape of highly pathogenic avian #influenza strain A(#H5N1) in current #outbreak in #USA & global landscape, Virology: sciencedirect.com/science/arti

    The study evaluated the virus evolution, divergence, #transmission #patterns, and infection patterns. The study also illustrated entropy diversity in the #genome, #nucleotide diversity in the genome, and mutational landscape.

  9. #Evolution and mutational #landscape of highly pathogenic avian #influenza strain A(#H5N1) in current #outbreak in #USA & global landscape, Virology: sciencedirect.com/science/arti

    The study evaluated the virus evolution, divergence, #transmission #patterns, and infection patterns. The study also illustrated entropy diversity in the #genome, #nucleotide diversity in the genome, and mutational landscape.

  10. #Evolution and mutational #landscape of highly pathogenic avian #influenza strain A(#H5N1) in current #outbreak in #USA & global landscape, Virology: sciencedirect.com/science/arti

    The study evaluated the virus evolution, divergence, #transmission #patterns, and infection patterns. The study also illustrated entropy diversity in the #genome, #nucleotide diversity in the genome, and mutational landscape.

  11. #Proteasome regulation is disrupted in human #NGLY1 deficiency. @nlehrbach @gary_ruvkun &co find that in NGLY1-deficient #Celegans this depends on #nucleotide availability, suggesting that nucleotide restriction might mitigate such diseases #PLOSBiology plos.io/4cViY3y

  12. #Proteasome regulation is disrupted in human #NGLY1 deficiency. @nlehrbach @gary_ruvkun &co find that in NGLY1-deficient #Celegans this depends on #nucleotide availability, suggesting that nucleotide restriction might mitigate such diseases #PLOSBiology plos.io/4cViY3y

  13. #Proteasome regulation is disrupted in human #NGLY1 deficiency. @nlehrbach @gary_ruvkun &co find that in NGLY1-deficient #Celegans this depends on #nucleotide availability, suggesting that nucleotide restriction might mitigate such diseases #PLOSBiology plos.io/4cViY3y

  14. #Proteasome regulation is disrupted in human #NGLY1 deficiency. @nlehrbach @gary_ruvkun &co find that in NGLY1-deficient #Celegans this depends on #nucleotide availability, suggesting that nucleotide restriction might mitigate such diseases #PLOSBiology plos.io/4cViY3y

  15. #Proteasome regulation is disrupted in human #NGLY1 deficiency. @nlehrbach @gary_ruvkun &co find that in NGLY1-deficient #Celegans this depends on #nucleotide availability, suggesting that nucleotide restriction might mitigate such diseases #PLOSBiology plos.io/4cViY3y

  16. "Here, we studied the genomic architecture of DUP-TRP/INV-DUP by investigating the DNA of 24 patients identified by array comparative #genomic hybridization (aCGH) on whom we found evidence for the existence of 4 out of 4 predicted structural variant (SV) haplotypes..The point of template #switching in 4 samples was shown to be a segment of ∼2.2–5.5 kb of 100% #nucleotide similarity within inverted repeat pairs...inverted low-copy repeats act as recombinant substrates"

    cell.com/cell-genomics/fulltex

  17. "Here, we studied the genomic architecture of DUP-TRP/INV-DUP by investigating the DNA of 24 patients identified by array comparative #genomic hybridization (aCGH) on whom we found evidence for the existence of 4 out of 4 predicted structural variant (SV) haplotypes..The point of template #switching in 4 samples was shown to be a segment of ∼2.2–5.5 kb of 100% #nucleotide similarity within inverted repeat pairs...inverted low-copy repeats act as recombinant substrates"

    cell.com/cell-genomics/fulltex

  18. "Here, we studied the genomic architecture of DUP-TRP/INV-DUP by investigating the DNA of 24 patients identified by array comparative #genomic hybridization (aCGH) on whom we found evidence for the existence of 4 out of 4 predicted structural variant (SV) haplotypes..The point of template #switching in 4 samples was shown to be a segment of ∼2.2–5.5 kb of 100% #nucleotide similarity within inverted repeat pairs...inverted low-copy repeats act as recombinant substrates"

    cell.com/cell-genomics/fulltex

  19. "Here, we studied the genomic architecture of DUP-TRP/INV-DUP by investigating the DNA of 24 patients identified by array comparative #genomic hybridization (aCGH) on whom we found evidence for the existence of 4 out of 4 predicted structural variant (SV) haplotypes..The point of template #switching in 4 samples was shown to be a segment of ∼2.2–5.5 kb of 100% #nucleotide similarity within inverted repeat pairs...inverted low-copy repeats act as recombinant substrates"

    cell.com/cell-genomics/fulltex

  20. "Here, we studied the genomic architecture of DUP-TRP/INV-DUP by investigating the DNA of 24 patients identified by array comparative #genomic hybridization (aCGH) on whom we found evidence for the existence of 4 out of 4 predicted structural variant (SV) haplotypes..The point of template #switching in 4 samples was shown to be a segment of ∼2.2–5.5 kb of 100% #nucleotide similarity within inverted repeat pairs...inverted low-copy repeats act as recombinant substrates"

    cell.com/cell-genomics/fulltex

  21. #Tumors can carry #mutations in hundreds of different #genes, and each of those genes may be mutated in different ways — some mutations simply replace one #DNA #nucleotide with another, while others insert or delete larger sections of DNA.
    #Biology #Genetics #Cancer #sflorg
    sflorg.com/2024/03/bio03122401

  22. #Tumors can carry #mutations in hundreds of different #genes, and each of those genes may be mutated in different ways — some mutations simply replace one #DNA #nucleotide with another, while others insert or delete larger sections of DNA.
    #Biology #Genetics #Cancer #sflorg
    sflorg.com/2024/03/bio03122401

  23. #Tumors can carry #mutations in hundreds of different #genes, and each of those genes may be mutated in different ways — some mutations simply replace one #DNA #nucleotide with another, while others insert or delete larger sections of DNA.
    #Biology #Genetics #Cancer #sflorg
    sflorg.com/2024/03/bio03122401

  24. #Tumors can carry #mutations in hundreds of different #genes, and each of those genes may be mutated in different ways — some mutations simply replace one #DNA #nucleotide with another, while others insert or delete larger sections of DNA.
    #Biology #Genetics #Cancer #sflorg
    sflorg.com/2024/03/bio03122401

  25. #Tumors can carry #mutations in hundreds of different #genes, and each of those genes may be mutated in different ways — some mutations simply replace one #DNA #nucleotide with another, while others insert or delete larger sections of DNA.
    #Biology #Genetics #Cancer #sflorg
    sflorg.com/2024/03/bio03122401

  26. `Furthermore, we show that 5′-FAD capping protects RNA from RIG-I mediated innate #immune recognition but does not stabilize the HCV #RNA. These results establish #capping with cellular metabolites as a novel #viral RNA-capping strategy, which could be used by other viruses and affect anti-viral treatment outcomes and persistence of #infection.`

    nature.com/articles/s41586-023

    #interesting #virology #medicine #molecularBiology #molecularBio #biology #ribonucleotide #nucleotide #immunology #pathology

  27. `Furthermore, we show that 5′-FAD capping protects RNA from RIG-I mediated innate #immune recognition but does not stabilize the HCV #RNA. These results establish #capping with cellular metabolites as a novel #viral RNA-capping strategy, which could be used by other viruses and affect anti-viral treatment outcomes and persistence of #infection.`

    nature.com/articles/s41586-023

    #interesting #virology #medicine #molecularBiology #molecularBio #biology #ribonucleotide #nucleotide #immunology #pathology

  28. `Furthermore, we show that 5′-FAD capping protects RNA from RIG-I mediated innate #immune recognition but does not stabilize the HCV #RNA. These results establish #capping with cellular metabolites as a novel #viral RNA-capping strategy, which could be used by other viruses and affect anti-viral treatment outcomes and persistence of #infection.`

    nature.com/articles/s41586-023

    #interesting #virology #medicine #molecularBiology #molecularBio #biology #ribonucleotide #nucleotide #immunology #pathology

  29. `Furthermore, we show that 5′-FAD capping protects RNA from RIG-I mediated innate #immune recognition but does not stabilize the HCV #RNA. These results establish #capping with cellular metabolites as a novel #viral RNA-capping strategy, which could be used by other viruses and affect anti-viral treatment outcomes and persistence of #infection.`

    nature.com/articles/s41586-023

    #interesting #virology #medicine #molecularBiology #molecularBio #biology #ribonucleotide #nucleotide #immunology #pathology

  30. `Furthermore, we show that 5′-FAD capping protects RNA from RIG-I mediated innate #immune recognition but does not stabilize the HCV #RNA. These results establish #capping with cellular metabolites as a novel #viral RNA-capping strategy, which could be used by other viruses and affect anti-viral treatment outcomes and persistence of #infection.`

    nature.com/articles/s41586-023

    #interesting #virology #medicine #molecularBiology #molecularBio #biology #ribonucleotide #nucleotide #immunology #pathology

  31. ''Our studies showed #combination #therapy of favipiravir and oseltamivir has little effect on virus #nucleotide #diversity, nor prevents the increase of oseltamivir - #resistant #variants.''

  32. ''Our studies showed #combination #therapy of favipiravir and oseltamivir has little effect on virus #nucleotide #diversity, nor prevents the increase of oseltamivir - #resistant #variants.''

  33. ''Our studies showed #combination #therapy of favipiravir and oseltamivir has little effect on virus #nucleotide #diversity, nor prevents the increase of oseltamivir - #resistant #variants.''