#precisionmedicine — Public Fediverse posts

Bayer receives FDA approval for first-line lung cancer therapy HYRNUO

Whippany-based Bayer said Sept. 9 that the U.S. Food and Drug Administration (FDA) granted accelerated approval to HYRNUO…
#Germany #DE #Europe #EU #Europa #Bayer #ChristineRoth #clinicaltrials #FDAapproval #HER2-mutatedNSCLC #HYRNUO #Lifesciences #LungCancer #NelsonAmbrogio #Oncology #Pharmaceuticals #PrecisionMedicine #sevabertinib #Whippany #XiuningLe
https://www.europesays.com/germany/88580/

https://www.europesays.com/ch/128585/ Diagnostics Innovation Hinges on Collaboration, Not Technology Alone #DiagnosticAccess #KitTang #KOSMOS #MolecularTumorBoard #OpenInnovation #PrecisionMedicine #Roche #RocheDiagnosticsKorea

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

📢 Call for Papers: AI for Real-World Evidence Generation in Biomedicine

⏳ Submission Deadline: 31 January 2027

🔗 Submit your work: https://spj.science.org/journal/csbj/si/ai-real-world-evidence-generation

#CallForPapers #RealWorldEvidence #RWE #ArtificialIntelligence #AIinHealthcare #BiomedicalAI #MachineLearning #ClinicalInformatics #ComputationalBiology #CausalAI #Multiomics #BiomarkerDiscovery #PrecisionMedicine #DigitalHealth #RegulatoryScience #BiomedicalResearch

Advancements in gastric cancer management:

🧪 Multimodality treatments improve survival
🔬 7.7% of global cancer deaths
📊 Early detection crucial: 33.7% diagnosed metastatic
🔍 Genetic profiling, immunotherapy emergent

#GastricCancer #Oncology #PrecisionMedicine

https://tnyp.me/mkzMBbpw/m

🔬 Is it time to challenge the single-target mindset in exosome research?

🔗 Engineering Magnetic Beads for Affinity Enrichment of Exosomes. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0170

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Exosomes #ExtracellularVesicles #Biotechnology #MagneticBeads #Bioengineering #Diagnostics #Nanobiotechnology #Biomarkers #DrugDelivery #PrecisionMedicine

Research Engineer / Post-Doctoral Researcher in Translational Research
CHU Clermont-Ferrand

See the full job description on jobRxiv: https://jobrxiv.org/job/chu-clermont-ferrand-27778-research-engineer-post-doctoral-researcher-in-translational-research/

#intensivecaremedicine #postdoctoralresearchfellow #precisionmedicine #preclinical #translationalresearch...
https://jobrxiv.org/job/chu-clermont-ferrand-27778-research-engineer-post-doctoral-researcher-in-translational-research/?fsp_sid=13112

Dynamic BH3 profiling (DBP) is an advanced functional assay that predicts the efficacy of specific cancer treatments by testing them directly on living tumor cells.
#MolecularOncology #PrecisionMedicine #CellBiology #Pharmacogenomics #sflorg
https://www.sflorg.com/2026/06/ongy06032601.html

A novel diagnostic blood test that analyzes thousands of proteins to predict how patients with non-small cell lung cancer (NSCLC) will respond to treatments like immunotherapy before therapy begins.
#Oncology #PrecisionMedicine #Proteomics #Biostatistics #sflorg
https://www.sflorg.com/2026/05/ongy05272601.html

Researchers have developed an unprecedentedly detailed genetic map illustrating how specific genetic variations dictate gene expression in the tissues responsible for human vision.
#Genetics #Ophthalmology #MolecularBiology #PrecisionMedicine #sflorg
https://www.sflorg.com/2026/05/gen05262601.html

📢 Call for Papers: Computational Spatial Omics - Multimodal Strategies for Systems Biology and Biomedical Discovery

⏳ Submission Deadline: 31 December 2026

🔗 Submit your work: https://spj.science.org/journal/csbj/si/computational-spatial-omics

#CallForPapers #SpatialOmics #SpatialTranscriptomics #SpatialProteomics #Metabolomics #Lipidomics #Multiomics #ComputationalBiology #SystemsBiology #Bioinformatics #AIinHealthcare #DigitalPathology #GraphNeuralNetworks #PrecisionMedicine

Adenine base editing, a highly targeted form of genetic medicine, has been successfully deployed in a preclinical mouse model to correct the specific DNA mutation (SCN1A) responsible for Dravet syndrome, a severe and often fatal form of childhood epilepsy.
#MolecularGenetics #Neurobiology #GeneTherapy #PrecisionMedicine #sflorg
https://www.sflorg.com/2026/05/gen05142601.html

🫁 On #WorldAsthmaDay, we're spotlighting a paper by #3TR investigating which biologic works best for which asthma patient.
📚 3TR analysed 5,853 records from 1990 to 2024 to find clues as to which biologic would work best for which patient.
👉 Read the paper: https://shorturl.at/gNsVq
#WorldAsthmaDay #PrecisionMedicine #IHITransformingHealth #HorizonEU

🧠 Could the brain reveal vision loss more accurately than traditional eye tests?

🔗 Using Steady-State Visual Evoked Potentials to Characterize Wide-Ranging Retinopathy Linked to CRB1: Implications for Clinical Trials. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0042

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Neuroscience #Ophthalmology #RetinalDiseases #GeneTherapy #EEG #BrainResearch #DigitalHealth #PrecisionMedicine #Neuroimaging

Microproteins Linked to Heart and Brain Health Elevated by Mediterranean Diet

Credit: Nazar Abbas Photography/Getty Images Researchers at the USC Leonar…
#dining #cooking #diet #food #MediterraneanDiet #Biomarkers #cellularprotein #diettherapy #Mediterranean #Mitochondria #neurotoxicity #news&features #oxidativestress #precisionmedicine #proteins #topics #translationalresearch
https://www.diningandcooking.com/2624302/microproteins-linked-to-heart-and-brain-health-elevated-by-mediterranean-diet/

Crucially, this method helps address the "ancestry gap" by reducing the inherent biases found in smaller, human-designed gene panels.

Read the full study here:
https://www.nature.com/articles/s41698-026-01390-5 🔗

#PrecisionMedicine #Genomics #CancerResearch #HealthEquity #Bioinformatics

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Why should we have to choose between the depth of a targeted panel and the breadth of whole-exome sequencing (WES)?

In our latest paper in npj Precision Oncology, we present a way to move beyond the limitations of traditional targeted panels.

(1/3)

#Genomics #PrecisionMedicine #Bioinformatics #CancerResearch #BioTech #npjPrecisionOncology

Patient-Derived Brain Organoids Offer Insights for Alzheimer's Treatments

📰 Original title: Lab-Grown Mini Brains Could Aid Alzheimer's Research

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/patient-derived-brain-organoids-offer-insights-for-alzheimers-treatments/?redirpost=f05f76a6-046e-4c20-b0d0-acb7b6cdf750

#health #alzheimers #brainorganoids #precisionmedicine

🧬 What if disease isn’t written in DNA, but in how RNA is edited and spliced?

🔗 Long-Read Sequencing Reveals RNA Splicing Complexity in Human Diseases. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0052

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#RNASequencing #Genomics #Transcriptomics #PrecisionMedicine #MolecularBiology #Bioinformatics #NextGenSequencing #RNA #DNA

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

More isn’t always better, precision is. Understanding dosage in immunotherapy is complex. We’re breaking down the science of cell counts and how we determine the specific strength needed to target your unique case at Cancer Killer Cells.

Learn the science behind the dosage. https://justpaste.it/f7926

: #PrecisionMedicine #CancerFighter #Biotech #NKCells #CancerKillerCells

📢 Call for Papers: Advanced 3D Tissue Models for Improving Translational Pharmacology and Toxicology

⏳ Submission Deadline: 30 November 2026

🔗 Submit your work: https://spj.science.org/journal/csbj/si/advanced-3d-tissue-models

#CallForPapers #DrugDiscovery #Toxicology #3DTissueModels #Organoids #PrecisionMedicine #Bioengineering #Pharmacology

🧬 Why are we still studying genes in isolation when biology works as a network?

🔗 multiDEGGs: Single or Multiomic Differential Network Analysis for Biomarker Discovery and Feature Engineering for Predictive Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0001

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Bioinformatics #Multiomics #MachineLearning #PrecisionMedicine #DataScience #Biomarkers

🔬🦷 Are current dental diagnostics too late to catch the earliest stages of fluorosis?

🔗 Salivary Proteomic Signatures Reveal Novel Mechanistic Insights into Moderate Dental Fluorosis Pathogenesis and Oral Homeostasis Disruption. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0003

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#OralHealth #Fluorosis #Biomarkers #PrecisionMedicine #DentalResearch #Proteomics #PrecisionMedicine #SalivaDiagnostics

⏱️ Could a delayed immune response be silently predicting your next heart event?

🔗 Predicting Cardiovascular Events with Time-Lagged Inflammatory Dynamics: Stochastic Delay Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0005

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Cardiology #Biomarkers #AIinHealthcare #PrecisionMedicine #PreventiveHealthcare #MedicalResearch #DigitalTwins #HealthTech

3 gene editing technologies transforming biology 🧬

CRISPR-Cas9: targeted cutting → knockout or insertion

Base editing: single-nucleotide changes, no double-strand breaks  

Prime editing: insert, delete, or replace sequences with precision

For aging research: correcting genetic changes, enhancing repair, engineering resilience

#CRISPR #GeneEditing #Biotechnology #AgingResearch #PrecisionMedicine

AI Human Genetics Platform Mystra Debuts for Drug Discovery, Validation

Officially unveiled at the American Society of Human Genetics (ASHG) 2025 meeting held in Boston, Genomics has launched…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Artificialintelligence #drugdevelopment(pharmacology) #Drugdiscovery #Genome-wideassociationstudies #genomics #HumanGenetics #mystra #omics #precisionmedicine #Science #topics
https://www.newsbeep.com/us/239086/

🧬 Can quantum intelligence unlock new ways to understand genetic mutations?

🔗 Quantum neural networks meet federated learning for DNA mutation prediction. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.036

📚 CSBJ Quantum Biology & Biophotonics: https://www.csbj.org/qbio

#Genomics #QuantumBiology #DNA #QuantumComputing #BiomedicalAI #FederatedLearning #PrecisionMedicine #ArtificialIntelligence #QNN

🤖 Can large language models (LLMs) reliably extract biomedical knowledge from scientific literature?

🔗 Developing foundations for biomedical knowledgebases from literature using large language models – A systematic assessment. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.042

📚 CSBJ: https://www.csbj.org/

#AI #LargeLanguageModels #BiomedicalAI #Bioinformatics #ComputationalBiology #DigitalHealth #ArtificialIntelligence #DataScience #PrecisionMedicine

🔎 How can AI-powered tools help scientists uncover hidden connections in disease research?

🔗 Darling (v2.0): Mining disease-related databases for the detection of biomedical entity associations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.025

📚 CSBJ: https://www.csbj.org/

#AIinScience #BiomedicalTextMining #Genomics #PrecisionMedicine #Bioinformatics #OpenScience #BiomedicalResearch #BiomedicalAI #LiteratureMining #SystemsBiology #Omics #KnowledgeDiscovery

A women's health biotechnology company is partnering with a Brazilian drug maker to evaluate a precision target and treatment for ovarian health disorders.

https://sciencebusiness.technewslit.com/?p=45083

#News #Press #Science #Business #Biotechnology #Collaboration #Melatonin #WomensHealth #Ovaries #PCOS #PrecisionMedicine #Infertility #Brazil #Preclinical #Licensing