#precisionmedicine — Public Fediverse posts

Bayer receives FDA approval for first-line lung cancer therapy HYRNUO

Whippany-based Bayer said Sept. 9 that the U.S. Food and Drug Administration (FDA) granted accelerated approval to HYRNUO…
#Germany #DE #Europe #EU #Europa #Bayer #ChristineRoth #clinicaltrials #FDAapproval #HER2-mutatedNSCLC #HYRNUO #Lifesciences #LungCancer #NelsonAmbrogio #Oncology #Pharmaceuticals #PrecisionMedicine #sevabertinib #Whippany #XiuningLe
https://www.europesays.com/germany/88580/

https://www.europesays.com/ch/128585/ Diagnostics Innovation Hinges on Collaboration, Not Technology Alone #DiagnosticAccess #KitTang #KOSMOS #MolecularTumorBoard #OpenInnovation #PrecisionMedicine #Roche #RocheDiagnosticsKorea

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

🔬 What if a tumor sample could serve as its own reference?

🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0219

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

📢 Call for Papers: AI for Real-World Evidence Generation in Biomedicine

⏳ Submission Deadline: 31 January 2027

🔗 Submit your work: https://spj.science.org/journal/csbj/si/ai-real-world-evidence-generation

#CallForPapers #RealWorldEvidence #RWE #ArtificialIntelligence #AIinHealthcare #BiomedicalAI #MachineLearning #ClinicalInformatics #ComputationalBiology #CausalAI #Multiomics #BiomarkerDiscovery #PrecisionMedicine #DigitalHealth #RegulatoryScience #BiomedicalResearch

Research Engineer / Post-Doctoral Researcher in Translational Research
CHU Clermont-Ferrand

See the full job description on jobRxiv: https://jobrxiv.org/job/chu-clermont-ferrand-27778-research-engineer-post-doctoral-researcher-in-translational-research/

#intensivecaremedicine #postdoctoralresearchfellow #precisionmedicine #preclinical #translationalresearch...
https://jobrxiv.org/job/chu-clermont-ferrand-27778-research-engineer-post-doctoral-researcher-in-translational-research/?fsp_sid=13112

https://www.europesays.com/ch/87225/ Novartis charts next US investment with new radiopharma plant #CancerDrugs #DrugManufacturing #facilities #FiercePharmaHomepage #Florida #Lutathera #Manufacturing #Novartis #Oncology #Pharma #Pluvicto #PrecisionMedicine #radiopharmaceuticals #tariffs #UnitedStates

🔬 Can structural shifts at the atomic level decide treatment outcomes in AML?

🔗 Understanding the characteristic behaviour of the wild-type and mutant structure of FLT3 protein by computational methods. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.023

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #StructuralBiology #CancerResearch #AML #DrugDiscovery #PrecisionMedicine #KinaseResearch #Bioinformatics

🤖 Can AI help us predict and prevent off-target effects in PROTAC drug design?

🔗 Predicting PROTAC off-target effects via warhead involvement levels in drug–target interactions using graph attention neural networks. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.028

📚 CSBJ: https://www.csbj.org/

#DrugDevelopment #StructuralBiology #ChemicalBiology #PROTAC #DrugDiscovery #Cheminformatics #Bioinformatics #PrecisionMedicine #TargetedProteinDegradation

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

A women's health biotechnology company is partnering with a Brazilian drug maker to evaluate a precision target and treatment for ovarian health disorders.

https://sciencebusiness.technewslit.com/?p=45083

#News #Press #Science #Business #Biotechnology #Collaboration #Melatonin #WomensHealth #Ovaries #PCOS #PrecisionMedicine #Infertility #Brazil #Preclinical #Licensing

'Using two independent real-world datasets from three different countries and an independent validation cohort based on the global, double-blind, placebo-controlled, phase 3 RECOURSE trial, we demonstrate that codon-specific KRAS mutations predict OS benefit for patients treated with the chemotherapeutic agent FTD/TPI in late-stage mCRC.'

#NatureMedicine #KRAS #PrecisionMedicine

https://www.nature.com/articles/s41591-023-02240-8#Sec7