#cd4 — Public Fediverse posts

For pre-meeting prep take a look at our Michigan Congressional District 4 candidates websites. Sean McCann will be present to meet with us on Wednesday at the Allegan Library. seanmccannforcongress.com www.diop4mi.com #Michigan #westmichigan #politics #democracy #Democrats #CD4

For pre-meeting prep take a look at our Michigan Congressional District 4 candidates websites. Sean McCann will be present to meet with us on Wednesday at the Allegan Library. seanmccannforcongress.com www.diop4mi.com #Michigan #westmichigan #politics #democracy #Democrats #CD4

For pre-meeting prep take a look at our Michigan Congressional District 4 candidates websites. Sean McCann will be present to meet with us on Wednesday at the Allegan Library.

https://seanmccannforcongress.com/
https://www.diop4mi.com/

#Michigan
#westmichigan
#politics
#democracy
#Democrats
#CD4

For pre-meeting prep take a look at our Michigan Congressional District 4 candidates websites. Sean McCann will be present to meet with us on Wednesday at the Allegan Library.

https://seanmccannforcongress.com/
https://www.diop4mi.com/

#Michigan
#westmichigan
#politics
#democracy
#Democrats
#CD4

#Influenza #vaccination post - #COVID19 expands vaccine-specific effector #CD4 T-cells and Tregs under positive influence of host trained innate #immunity, https://etidiohnew.blogspot.com/2025/12/influenza-vaccination-post-covid19.html

#Influenza #vaccination post - #COVID19 expands vaccine-specific effector #CD4 T-cells and Tregs under positive influence of host trained innate #immunity, https://etidiohnew.blogspot.com/2025/12/influenza-vaccination-post-covid19.html

Perforin is the substance T and NK cells use to drill into an infected cell and kill it. Selin and Gill’s studies suggest that ME/CFS and long-COVID patients’ T cells produce almost no perforin

https://www.healthrising.org/wp-content/uploads/2025/05/Perforin_Selin_Webinar_25.gif

[alt text: graphs of perforin in two classes of cell. The healthy controls are tall grey bars, compared to 1/10 to 1/3 as tall bars for Long COVID and ME/CFS groups.]

they also found

a huge increase in a distinct type of T-cell called double-positive T-cell (CD4+ CD8+) in people with ME/CFS and/or long COVID. Instead of being differentiated into the two usual major T-cell subsets CD4 (helper/regulatory) and CD8 (killer) T-cells, these hybrid T-cells look like both CD4 and CD8 T-cells at the same time.

Selin found that these cells increased 8-9 fold in ME/CFS and long-COVID patients.

which compensates in part for the lower perforin, but also led to

a “highly dysregulated” cytotoxic T-cell immune response [...] That suggested that the immune system was kind of flailing around, trying to come up with an answer.

from https://www.healthrising.org/blog/2025/05/15/t-cell-exhaustion-chronic-fatigue-long-covid/

#COVID #COVID19 #MECFS #LongCOVID #CovidIsNotOver #TCells #NKCells #CD8 #CD4

Perforin is the substance T and NK cells use to drill into an infected cell and kill it. Selin and Gill’s studies suggest that ME/CFS and long-COVID patients’ T cells produce almost no perforin

https://www.healthrising.org/wp-content/uploads/2025/05/Perforin_Selin_Webinar_25.gif

[alt text: graphs of perforin in two classes of cell. The healthy controls are tall grey bars, compared to 1/10 to 1/3 as tall bars for Long COVID and ME/CFS groups.]

they also found

a huge increase in a distinct type of T-cell called double-positive T-cell (CD4+ CD8+) in people with ME/CFS and/or long COVID. Instead of being differentiated into the two usual major T-cell subsets CD4 (helper/regulatory) and CD8 (killer) T-cells, these hybrid T-cells look like both CD4 and CD8 T-cells at the same time.

Selin found that these cells increased 8-9 fold in ME/CFS and long-COVID patients.

which compensates in part for the lower perforin, but also led to

a “highly dysregulated” cytotoxic T-cell immune response [...] That suggested that the immune system was kind of flailing around, trying to come up with an answer.

from https://www.healthrising.org/blog/2025/05/15/t-cell-exhaustion-chronic-fatigue-long-covid/

#COVID #COVID19 #MECFS #LongCOVID #CovidIsNotOver #TCells #NKCells #CD8 #CD4

Antiviral #CD4+ T and myeloid cell responses to #influenza #vaccines are attenuated in older #adults, https://etidiohnew.blogspot.com/2025/05/antiviral-cd4-t-and-myeloid-cell.html

Antiviral #CD4+ T and myeloid cell responses to #influenza #vaccines are attenuated in older #adults, https://etidiohnew.blogspot.com/2025/05/antiviral-cd4-t-and-myeloid-cell.html

A #vaccine #platform targeting #lung-resident memory #CD4+ T-cells provides #protection against heterosubtypic #influenza infections in mice and #ferrets

Source: Nature Communications, AbstractLung tissue-resident memory T (TRM) cells induced by influenza vaccination are crucial for heterosubtypic immunity upon re-exposure to the influenza virus, enabling rapid and robust responses upon reactivation. To enhance the efficacy of influenza vaccines, we induce the…

https://etidioh.wordpress.com/2024/11/29/a-vaccine-platform-targeting-lung-resident-memory-cd4-t-cells-provides-protection-against-heterosubtypic-influenza-infections-in-mice-and-ferrets/

A #vaccine #platform targeting #lung-resident memory #CD4+ T-cells provides #protection against heterosubtypic #influenza infections in mice and #ferrets

Source: Nature Communications, AbstractLung tissue-resident memory T (TRM) cells induced by influenza vaccination are crucial for heterosubtypic immunity upon re-exposure to the influenza virus, enabling rapid and robust responses upon reactivation. To enhance the efficacy of influenza vaccines, we induce the…

https://etidioh.wordpress.com/2024/11/29/a-vaccine-platform-targeting-lung-resident-memory-cd4-t-cells-provides-protection-against-heterosubtypic-influenza-infections-in-mice-and-ferrets/

#Nasal #tissue-resident #memory #CD4+ T cells persist after #influenza A virus #infection and provide heterosubtypic #protection, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.07.06.602325v1

Here, we find that, after IAV infection, antigen-specific CD4 TRM persist in the nasal tissue (NT) compartment and play a prime role in local viral clearance.

#Nasal #tissue-resident #memory #CD4+ T cells persist after #influenza A virus #infection and provide heterosubtypic #protection, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.07.06.602325v1

Here, we find that, after IAV infection, antigen-specific CD4 TRM persist in the nasal tissue (NT) compartment and play a prime role in local viral clearance.

@knittingknots2

I spend a lot of time in #CD4. The Dems have an uphill battle, but yeah, this was a poor decision by Boebert won't help Republicans.

However, one of the Dem challengers isn't any better than Boebert:

https://coloradonewsline.com/2024/01/08/family-conflict-colorado-ike-mccorkle/

@knittingknots2

I spend a lot of time in #CD4. The Dems have an uphill battle, but yeah, this was a poor decision by Boebert won't help Republicans.

However, one of the Dem challengers isn't any better than Boebert:

https://coloradonewsline.com/2024/01/08/family-conflict-colorado-ike-mccorkle/

Name the type of leukocyte most likely to be CD4+ and at least 5 other types of leukocyte that may also be CD4+.

#CD4 (cluster of differentiation 4): Human Protein Atlas mRNA cell type distributions & GPMDB protein tissue tabbulations. #proteomics

Name the type of leukocyte most likely to be CD4+ and at least 5 other types of leukocyte that may also be CD4+.

#CD4 (cluster of differentiation 4): Human Protein Atlas mRNA cell type distributions & GPMDB protein tissue tabbulations. #proteomics

Strong #CD4 T-Cell Responses to Ancestral and #Variant Spike Proteins Are Established by NVX-CoV2373 SARS-CoV-2 Primary Vaccination https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad163/7175115?rss=1

“Progressive” @nithyavraman has voted YES on the LAPD budget each year she’s been in office. @hugoforcd13’s first opportunity and he voted YES on increasing the LAPD budget.

@eunissesh is the only one to vote NO. It’s worth pointing out since others are afraid to step up.

R/T [email protected]

https://bird.makeup/users/pplscitycouncil/statuses/1659278690595880961

https://bird.makeup/users/eunissesh/statuses/1659274513090060321

#LosAngeles #LA #NithyaRaman #Eunisses #EunissesHernamdez #CD1 #CD4 #ACAB #Abolition #PoliceAbolition #LACityBudget

Phone bank for @JennMcClellanVA at Center for Common Ground’s events, “National Guided Phone Bank: Virginia CD4 Special Election” – sign up now! #cfcg
#DemCastVA #Virginia #CD4
https://www.mobilize.us/cfcg-rov/event/546686/?rname=Gail&share_context=event_details&share_medium=twitter

Phone bank for @JennMcClellanVA at Center for Common Ground’s events, “National Guided Phone Bank: Virginia CD4 Special Election” – sign up now! #cfcg
#DemCastVA #Virginia #CD4
https://www.mobilize.us/cfcg-rov/event/546686/?rname=Gail&share_context=event_details&share_medium=twitter

Phone bank for Jennifer McClellan in the Primary for Special Election for Virginia CD4 US House Seat, “Team McClellan Get Out the Vote! Virtual Phone Bank” – sign up now!
#DemCastVA @JennMcClellanVA
#USHouse
Virginia #CD4
#VirginiaDemocrats
#VirginiaDems
#SpecialElection

https://www.mobilize.us/mobilize/event/545937/

Phone bank for Jennifer McClellan in the Primary for Special Election for Virginia CD4 US House Seat, “Team McClellan Get Out the Vote! Virtual Phone Bank” – sign up now!
#DemCastVA @JennMcClellanVA
#USHouse
Virginia #CD4
#VirginiaDemocrats
#VirginiaDems
#SpecialElection

https://www.mobilize.us/mobilize/event/545937/