#astrocyte — Public Fediverse posts

Newly mapped #brain networks link far-flung regions
#Astrocyte networks in #mice link distant brain regions in ways nerve cell wiring does not.
This system, made of star-shaped cells called #astrocytes, is no relic, a new study reports. It’s operational, linking locales near and far in flexible, mysterious ways.
What’s more, astrocyte networks may also have roles in disorders such as #Alzheimer’s disease, traumatic brain injuries and stroke.
https://www.sciencenews.org/article/astrocytes-brain-networks-communicate
https://archive.ph/MKkcZ

Newly mapped #brain networks link far-flung regions
#Astrocyte networks in #mice link distant brain regions in ways nerve cell wiring does not.
This system, made of star-shaped cells called #astrocytes, is no relic, a new study reports. It’s operational, linking locales near and far in flexible, mysterious ways.
What’s more, astrocyte networks may also have roles in disorders such as #Alzheimer’s disease, traumatic brain injuries and stroke.
https://www.sciencenews.org/article/astrocytes-brain-networks-communicate
https://archive.ph/MKkcZ

To capture this local heterogeneity, the authors developed a #multiphoton #FLIM approach with the Na⁺ indicator ING-2 and #astrocyte labeling, enabling quantitative Na⁺ measurements in individual #astrocytes and their processes. This is important because astrocytic Na⁺ is not just a bulk somatic variable. It varies locally across branches and subdomains, where K⁺ uptake and #glutamate-linked Na⁺ influx are regulated.

#Neuroscience #Imaging

To capture this local heterogeneity, the authors developed a #multiphoton #FLIM approach with the Na⁺ indicator ING-2 and #astrocyte labeling, enabling quantitative Na⁺ measurements in individual #astrocytes and their processes. This is important because astrocytic Na⁺ is not just a bulk somatic variable. It varies locally across branches and subdomains, where K⁺ uptake and #glutamate-linked Na⁺ influx are regulated.

#Neuroscience #Imaging

🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.

Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.

🌍 https://doi.org/10.1038/s41467-026-73435-z

#Neuroscience #Astrocytes #Neurobiology #NeuralDynamics

🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.

Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.

🌍 https://doi.org/10.1038/s41467-026-73435-z

#Neuroscience #Astrocytes #Neurobiology #NeuralDynamics

🧠 New paper by Cooper et al., who introduce a method to trace #astrocyte #gapjunction networks in vivo and show that astrocytes form selective, plastic networks linking specific #brain regions rather than one diffuse brain-wide syncytium. These networks can span long distances, differ from known #neuronal projections, and reorganize after sensory deprivation:

📄 https://www.nature.com/articles/s41586-026-10426-6

#Neuroscience #BrainConnectivity

🧠 New paper by Cooper et al., who introduce a method to trace #astrocyte #gapjunction networks in vivo and show that astrocytes form selective, plastic networks linking specific #brain regions rather than one diffuse brain-wide syncytium. These networks can span long distances, differ from known #neuronal projections, and reorganize after sensory deprivation:

📄 https://www.nature.com/articles/s41586-026-10426-6

#Neuroscience #BrainConnectivity

Helping Spinal Cords Heal. The neural support cell, the astrocyte, plays a crucial role in spinal cord healing following injury. #spinalcord #injury #astrocyte #ccn1
https://www.instagram.com/p/DVMhrgcjtgO/

Helping Spinal Cords Heal. The neural support cell, the astrocyte, plays a crucial role in spinal cord healing following injury. #spinalcord #injury #astrocyte #ccn1
https://www.instagram.com/p/DVMhrgcjtgO/

Magnetic Cell Sorter 🇺🇸

#Astrocytes #CellsandOrganelles #GLAST #GLAST+ #Magnetic #Sorter #astrocyte #brain

⏩ 2 new pictures from NIH BioArt https://commons.wikimedia.org/wiki/Special:ListFiles?limit=22&user=OptimusPrimeBot&ilshowall=1&offset=20251216025720

Magnetic Cell Sorter 🇺🇸

#Astrocytes #CellsandOrganelles #GLAST #GLAST+ #Magnetic #Sorter #astrocyte #brain

⏩ 2 new pictures from NIH BioArt https://commons.wikimedia.org/wiki/Special:ListFiles?limit=22&user=OptimusPrimeBot&ilshowall=1&offset=20251216025720

Astrocyte 🇺🇸

#CellsandOrganelles #astrocyte #brain #cell #glia #gliacells #nervoussystemcells

⏩ 2 new pictures from NIH BioArt https://commons.wikimedia.org/wiki/Special:ListFiles?limit=40&user=OptimusPrimeBot&ilshowall=1&offset=20251213025809

Astrocyte 🇺🇸

#CellsandOrganelles #astrocyte #brain #cell #glia #gliacells #nervoussystemcells

⏩ 2 new pictures from NIH BioArt https://commons.wikimedia.org/wiki/Special:ListFiles?limit=40&user=OptimusPrimeBot&ilshowall=1&offset=20251213025809

What's the function of #histamine -1-receptors (H1Rs) on cortical astrocytes? @KiraPoskanzer & co show that astrocytic H1R signaling modulates Ca2+ activity, extracellular adenosine & REM #sleep, revealing a key #astrocyte role in sleep-wake regulation @PLOSBiology https://plos.io/4gRj9Ap

What's the function of #histamine -1-receptors (H1Rs) on cortical astrocytes? @KiraPoskanzer & co show that astrocytic H1R signaling modulates Ca2+ activity, extracellular adenosine & REM #sleep, revealing a key #astrocyte role in sleep-wake regulation @PLOSBiology https://plos.io/4gRj9Ap

#COVID19-associated #neuroinflammation and #astrocyte death in the #brain linked to ORF3a-induced activation of Sur1-mediated ion channels, https://etidiohnew.blogspot.com/2025/08/covid19-associated-neuroinflammation.html

#COVID19-associated #neuroinflammation and #astrocyte death in the #brain linked to ORF3a-induced activation of Sur1-mediated ion channels, https://etidiohnew.blogspot.com/2025/08/covid19-associated-neuroinflammation.html

i've seen a few papers in the last 10 years demonstrating direct #astrocyte involvement in a variety of brain functions normally associated with #neurons... does this mean that the definition of the #connectome should be somehow augmented with astrocyte topologies, relative to the neuronal ones?

i've seen a few papers in the last 10 years demonstrating direct #astrocyte involvement in a variety of brain functions normally associated with #neurons... does this mean that the definition of the #connectome should be somehow augmented with astrocyte topologies, relative to the neuronal ones?

For the #astrocyte crowd?

Exclusive early bird price just for you -Recycling 2023
Dear Colleague‍ ,

I would like to take the privilege to invite you to be an honorable speaker and deliver a presentation at 2nd International Conference and Expo on Recycling and Waste Management during 26-27 June, 2023 at Paris, France. If possible, I would appreciate receiving your abstract submission on or before May. 20. 2023.

#AcademicSpam

Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer’s disease brains

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Aβ #AβFibrils #Immunotherapy #Lecanemab

https://www.cell.com/neuron/fulltext/S0896-6273(23)00269-6

Alzheimer’s Drug Lecanemab Shields Brain from Free-Roaming Amyloid Fibrils

Amyloid beta protein forms small aggregates that disrupt brain function in Alzheimer’s disease.
Lecanemab, a recently FDA-approved Alzheimer’s treatment, can neutralize these disruptive aggregates, hinting at its potential to slow down the disease’s cognitive decline.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Immunotherapy #Lecanemab

https://neurosciencenews.com/amyloid-fibril-neuropharmacology-23207/

A new study has revealed that astrocytes, a type of brain cell, can turn into neurons and restore memory in mice with Alzheimer’s disease. Astrocytes are star-shaped glial cells that support and protect neurons. The study found that activating a gene called Ascl1 in astrocytes can reprogram them into functional neurons and reverse cognitive decline. The study offers a potential new strategy for treating Alzheimer’s disease.

#astrocyte #neuron #Alzheimer’s

https://neurosciencenews.com/astrocyte-neuron-alzheimers-neuroscience-23024/

A new study has revealed that astrocytes, a type of brain cell, can turn into neurons and restore memory in mice with Alzheimer’s disease. Astrocytes are star-shaped glial cells that support and protect neurons. The study found that activating a gene called Ascl1 in astrocytes can reprogram them into functional neurons and reverse cognitive decline. The study offers a potential new strategy for treating Alzheimer’s disease.

#astrocyte #neuron #Alzheimer’s

https://neurosciencenews.com/astrocyte-neuron-alzheimers-neuroscience-23024/

Imaging Study Implicates Reactive Astrocyte-Neuron Interaction in Alzheimer’s Cognitive Decline

PET imaging with 11C-acetate and 18F-FDG was used to visualize the reactive astrocyte-induced acetate hypermetabolism and associated neuronal glucose hypometabolism in brains with neuroinflammation and Alzheimer’s Disease.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #BrainImaging #Neuroimaging #NeuroMetabolism #AcetateHypermetabolism #GlucoseHypometabolism #NeuroInflammation #CognitiveDecline #CognitiveDysfunction

https://www.genengnews.com/topics/drug-discovery/imaging-study-implicates-neuron-interaction-in-ad-alzheimers-cognitive-decline/

For the #astrocyte lovers out there: fantastic new work from Aina Badia et al., showing ezrin-mediated PAP retraction in fear learning!
Such.Pretty.Data ❤️😍🌟

Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory - Biological Psychiatry
https://www.biologicalpsychiatryjournal.com/article/S0006-3223(22)01705-X/fulltext#.Y9o3jEhUpdQ.twitter

Another not-to-be-missed talk from the WWN series, tomorrow @ 5pm CET

Cagla Eroglu | How do Astrocytes Sculpt Synaptic Circuits?
https://www.world-wide.org/seminar/8674/

#neuroscience #synapse #Astrocyte #systemsneuro #circuits

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

And axo-glial interactions in our cells of interest. Thanks to @schierlab for their scRNAseq work #glia #astrocyte #axon #oxytocin 17/n