#neuroimmunology — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #neuroimmunology, aggregated by home.social.
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Severe #narcolepsy with cataplexy is caused by the degeneration of neurons in two distinct regions of the brain: the hypothalamus and the locus coeruleus. This dual-region damage disrupts the production of both hypocretin and norepinephrine, which are critical chemical messengers for regulating wakefulness and muscle tone.
#Neuroscience #Neurology #Neuroimmunology #Psychiatry #sflorg
https://www.sflorg.com/2026/05/ns05012601.html -
ERC-funded 3-year postdoc position with Michael Dolan in Dublin, Ireland, on neuroimunology and genomics. To apply, write an email to Michael.
#PhDJobs #neuroscience #neuroimmunology #immunology #genomics
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Alzheimer’s disease: new three-minute test can spot memory issues – here’s how it works and what it can tell you https://theconversation.com/alzheimers-disease-new-three-minute-test-can-spot-memory-issues-heres-how-it-works-and-what-it-can-tell-you-264519 #neuroimmunology #health #science #STEM
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--Postdoctoral Fellowship in Structural Neurophysiology at CSHL—
Cold Spring Harbor Laboratory @Lab_FURUKAWAJoin us to conduct cutting-edge science and advance your career. #cryo-EM #electrophysiology #neuroscience #neuroimmunology
See the full job description on jobRxiv: https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-i...
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in-structural-neurophysiology-at-cshl/?fsp_sid=1530 -
--Postdoctoral Fellowship in Structural Neurophysiology at CSHL—
Cold Spring Harbor Laboratory @Lab_FURUKAWAJoin us to conduct cutting-edge science and advance your career. #cryo-EM #electrophysiology #neuroscience #neuroimmunology
See the full job description on jobRxiv: https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in...
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in-structural-neurophysiology-at-cshl/?fsp_sid=802 -
How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
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How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
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How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
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How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
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How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
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When Brain Balance Tips: Understanding Neuroinflammation After Head Injuries
#BrainHealth #Microglia #Neuroinflammation #Neurodegeneration #Alzheimers #Parkinsons #BrainScience #Neuroscience #BrainAging #Neurobiology #ProteinAggregates #BrainRepair #Neuroimmunology #BrainCells #CognitiveHealth
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The Vagus Nerve and the Microbiome: Keys to a Balanced Mind and Body
#GutBrainConnection #VagusNerve #Microbiome #MentalHealth #GutHealth #StressRelief #MindBodyBalance #WellnessJourney #Psychobiotics #YogaForHealth #Mindfulness #HealthAndHappiness #Neuroimmunology #HolisticHealth
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Did you know your immune system can influence your emotions? Discover how IL-17 toggles between anxiety and sociability. #NeuroImmunology #MentalHealth #IL17
https://geekoo.news/how-immune-molecules-shape-our-emotions-the-dual-role-of-il-17/
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#Biomaterials to regenerate the #NervousSystem: @CZ_Stiftung sponsors new InteReg project, a collaboration of @uni_mainz_eng, @mpi_polymer, and @LIRgGmbH, with EUR 6 million // #NeuralRegeneration #neurobiology #neuroimmunology #chemistry #PolymerResearch
https://nachrichten.idw-online.de/2024/12/10/biomaterials-to-regenerate-the-nervous-system-carl-zeiss-foundation-sponsors-intereg-project-at-mainz-university -
Evidence is building that the brain is far from sterile and infection underlies many neurodegenerative conditions.
Preprint of a study of rRNA in brains: https://www.biorxiv.org/content/10.1101/2023.02.06.527297v1
#Microbiome #InfectiousDisease #Dementia #NeurodegenerativeDiseases #BrainInfections #NeuroInfectiousAgents #NeuroImmunology
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Evidence is building that the brain is far from sterile and infection underlies many neurodegenerative conditions.
Preprint of a study of rRNA in brains: https://www.biorxiv.org/content/10.1101/2023.02.06.527297v1
#Microbiome #InfectiousDisease #Dementia #NeurodegenerativeDiseases #BrainInfections #NeuroInfectiousAgents #NeuroImmunology
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New #podcast episode! Dr. Jony Kipnis talks about his work in #neuroimmunology, interests outside of #science, career path, failures, successes, & exciting research using immunotherapy to reduce damage after central nervous system injury. 🧪 🧠📈 #scicomm www.peoplebehindthescience.com/dr-jonathan-...
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New #podcast episode! Dr. Jony Kipnis talks about his work in #neuroimmunology, interests outside of #science, career path, failures, successes, and exciting research using immunotherapy to reduce damage after central nervous system injury.
https://www.peoplebehindthescience.com/dr-jonathan-kipnis/
#neuroscience #immunology #research #scicomm #sciencecommunication #podcasts #STEM
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'We used Bacillus Calmette-Guerin (BCG), a live-attenuated vaccine, to train the innate immune system and detected epigenetic reprogramming of brain-resident myeloid cells and functional restoration of myelin debris clearance and lesion recovery.'
#Immunology #Neuroimmunology
https://www.cell.com/immunity/fulltext/S1074-7613(24)00348-0 -
'Our findings position STING as a central regulator of the detrimental neuronal inflammatory stress response, integrating inflammation with glutamate signaling to cause neuronal cell death, and present it as a tractable target for treating neurodegeneration in MS.'
#Immunology #Neuroimmunology #Autoimmunity #multiplesclerosis -
'We uncover that tumor cells mimic the anti-inflammatory mechanism of CNS to evade anti-tumor immunity and NAT8L is a potential target to enhance efficacy of anti-cancer agents.'
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'However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysis of the transcriptomes of murine Treg and conventional T cells (Tconv), we observe that the proenkephalin gene (Penk), encoding the precursor of analgesic opioid peptides, ranks among the top 25 genes most enriched in Treg cells.'
#Immunology #Preprint #Neuroimmunology #Treg
https://www.biorxiv.org/content/10.1101/2023.09.12.557326v2 -
'One common emerging principle is that microglial reactivity triggered by even relatively mild Covid occurring in the respiratory system, not directly infecting the brain or other kinds of immune challenges can trigger this reactivity of microglia and consequently dysregulate the normal interactions between cells and the brain'
Michele Monje#Covid #Covid19 #LongCovid #Immunology #NeuroImmunology
https://erictopol.substack.com/p/michelle-monje-the-brain-in-long
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Researchers discovered that #Bcells play an active role in teaching #Tcells not to attack the body itself. If the "training" fails, #autoimmunediseases such as #neuromyelitis optica can develop: http://go.tum.de/562972
📷J. Böttcher, T. Korn
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#Neuroimmunology #NeuroCovid #LongCovid Monitor #COVID19 patients for Parkinson’s symptoms, scientists say. The Virus infects dopaminergic neurons in brain, study finds, stopping cell division.
https://parkinsonsnewstoday.com/news/covid-19-dopaminergic-neurons-parkinsons-link-possible/
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'Drucker and his colleagues noticed a potential clue: receptors for GLP-1 are scarce in immune cells in many tissues in which the hormone and its mimics reduce inflammation, but are abundant in the brain. To test the nervous system’s role, Drucker’s team began by inducing system-wide inflammation in mice.'
#Immunology #Inflammation #Neuroimmunology #Metabolism -
I enjoyed chatting with Dr. Malú Gámez Tansey about her research at the intersection of immunology, neuroscience, and genetics in this recent podcast episode. She shared some of her new findings, advances in neuroimmunology, and insights on important areas of opportunity in the field.
#parkinsonsdisease #parkinsons #neuroscience #podcast #podcasts #genetics #immunology #research #science #neuroimmunology #scicomm
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"Through tissue-specific manipulation of Nptx2, the authors demonstrated that the pituitary was a major source of NPTX2 in the serum, and the increased NPTX2 secretion by the pituitary affected immune balance by regulating the blood neutrophil-to-lymphocyte ratio. Intriguingly, Nptx2 up-regulation in corticotropes seemed to depend on IL-6 but not other cytokines tested."
#Immunology #Neuroimmunologyhttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002440
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Research Technician
SUNY Upstate Medical University
Opening for a Research technician at newly established lab at SUNY Upstate. Work in regenerative neuroscience, neuroimmunology, and glial biology.
See the full job description on jobRxiv: https://jobrxiv.org/job/suny-upstate-medical-university-27778-research-technician-2/?feed_id=68225
#mouse_models #neurobiology #neuroimmunology #ScienceJ...
https://jobrxiv.org/job/suny-upstate-medical-university-27778-research-technician-2/?feed_id=68225 -
Postdoctoral Fellow Neuroimmunology (Louveau Lab)
Lerner Research Institute Cleveland Clinic
The Louveau lab is recruiting
See the full job description on jobRxiv: https://jobrxiv.org/job/lerner-research-institute-cleveland-clinic-27778-postdoctral-fellow/?feed_id=67363
#immunology #Lymphatic_biology #neurodegeneration #neurodevelopmental_disorders #neuroimmunology #ScienceJobs #hir...
https://jobrxiv.org/job/lerner-research-institute-cleveland-clinic-27778-postdoctral-fellow/?feed_id=67363 -
"We show that socially stressed mice have elevated serum antibody concentrations. We also confirm that social stress leads to the expansion of specific T and B cell populations within the cervical lymph nodes, where brain-derived antigens are preferentially delivered."
#immunology #Neuroimmunology -
The newest Discovery Center created by the Paul G. Allen Frontiers Group at the Allen Institute will focus on defining and mapping the interactions between the nervous system and the immune system. https://www.geekwire.com/2023/allen-frontiers-group-neuroimmunology/ #Neuroimmunology
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Postdoctoral Fellow on Neuroimmunology
UAB School of Medicine
Research on #BloodBrainCommunications, #Glia, #BrainDevelopment, #ExtracellularVesicles, #ExtracellularParticles in #Neuroimmunology lab.
See the full job description on jobRxiv: https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=60090
#ScienceJobs #hir...
https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=60090 -
Postdoctoral Fellow on Neuroimmunology
UAB School of Medicine
Research on #BloodBrainCommunications, #Glia, #BrainDevelopment, #ExtracellularVesicles, #ExtracellularParticles in #Neuroimmunology lab.
See the full job description on jobRxiv: https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=58280
#ScienceJobs #hir...
https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=58280 -
Postdoctoral Fellow on Blood-Brain Communication
UAB School of Medicine
Research opportunities on #Blood-Brain-Communication via #ExtracellularVesicles, and #ExtracellularParticles in #Neuroimmunology Lab.
See the full job description on jobRxiv: https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=56672
#ScienceJob...
https://jobrxiv.org/job/uab-school-of-medicine-27778-postdoctoral-fellow-on-blood-brain-communication/?feed_id=56672 -
"They have investigated the brains of ageing mice, elucidating the source of the cGAS–STING trigger and the particular cells in which this pathway is activated (Fig. 1). Specifically, the authors find that cytosolic DNA derived from perturbed mitochondria activates the pathway in ageing microglia, the main immune cells in the brain — an observation that agrees with earlier findings that cGAS–STING is involved in activating microglia and in neuroinflammation"
#Immunology #Neuroimmunology #NeurodegenerativeDisease #InnateImmunity -
'For example, loss of function of the microglial gene Trem2 renders microglia dysfunctional and causes an early-onset neurodegenerative syndrome, and Trem2 variants are among the strongest genetic risk factors for AD. Thus, restoring microglial function represents a rational therapeutic approach. Here, we show that systemic hematopoietic cell transplantation followed by enhancement of microglia replacement restores microglial function in a Trem2 mutant mouse model of AD.'
#Alzheimer #NeurodegenerativeDisease #Microglia #Neuroimmunology
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00251-5#%20
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'We show here that lipid-mediated engagement of invariant natural killer T (iNKT) cells with enterochromaffin (EC) cells, a subset of intestinal epithelial cells, promoted peripheral serotonin (5-HT) release via a CD1d-dependent manner, regulating gut motility and hemostasis.'
#Immunology #MucosalImmunology #Neuroimmunology
https://www.cell.com/immunity/fulltext/S1074-7613(23)00236-4
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Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
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Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
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Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
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Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
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An in vivo neuroimmune organoid model to study human microglia phenotypes
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #BrainOrganoid #Organoid #NeuroimmuneOrganoid
#Microglia #Neuroimmune #Neuroimmunology -
Human Brain Organoids Reveal How Microglia Develop and Function
Researchers have developed human brain organoids that contain microglia, the immune cells of the brain.
The researchers found that microglia are influenced by the environment in which they develop and that they play a role in both development and disease.#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #BrainOrganoid #Organoid
#Microglia #Neuroimmune #Neuroimmunology -
This week in @sciencemagazine :
Pavel Hanč, Uli von Andrian, & colleagues (Harvard Med) elucidate multiple mechanisms by which #nociceptors can control #DendriticCell functions!
with an accompanying Perspective by Barbara Schraml:
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This week in @sciencemagazine :
Pavel Hanč, Uli von Andrian, & colleagues (Harvard Med) elucidate multiple mechanisms by which #nociceptors can control #DendriticCell functions!
with an accompanying Perspective by Barbara Schraml:
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This week in @sciencemagazine :
Pavel Hanč, Uli von Andrian, & colleagues (Harvard Med) elucidate multiple mechanisms by which #nociceptors can control #DendriticCell functions!
with an accompanying Perspective by Barbara Schraml:
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This week in @sciencemagazine :
Pavel Hanč, Uli von Andrian, & colleagues (Harvard Med) elucidate multiple mechanisms by which #nociceptors can control #DendriticCell functions!
with an accompanying Perspective by Barbara Schraml:
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This week in @sciencemagazine :
Pavel Hanč, Uli von Andrian, & colleagues (Harvard Med) elucidate multiple mechanisms by which #nociceptors can control #DendriticCell functions!
with an accompanying Perspective by Barbara Schraml:
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Injecting fractalkine into mouse models of multiple sclerosis increased the number of oligodendrocytes. Findings suggest fractalkine may help to slow the progression, or potentially halt Multiple Sclerosis.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neuroimmunology #Neuroinflammation #Demyelination #DemyelinatingDiseases #MultipleSclerosis #Oligodendrocytes #Fractalkine
https://neurosciencenews.com/multiple-sclerosis-fractslkine-222344/