Live and recent posts from across the Fediverse tagged #cytokines, aggregated by home.social.
Scientists find a way to boost plant grow without sacrificing immunity
Colorado State University researchers found that restoring cytokinin signaling in immune-activated Arabidopsis thaliana improved growth and reproductive output…
#NewsBeep #News #Science #AU #Australia #Cytokines #GlobalGoodNews #GreenGoodNews #hormones #immunity #NewDiscoveries #PlantBiology #plantgrowth #planthormones #Plants #research #Technology
https://www.newsbeep.com/au/909143/
GOOD NEWS ALERT
Scientists created an mRNA drug cocktail which not only targeted cancer but *kept it away* for one year after the #drug stopped.
Moving from #mice to humans is not easy but "if there was one approach I had to bet on, this is the one."
>The mRNA #immunotherapy may give the body a "memory" of #cancer cells, to attack them
>It might "be used as a platform to treat other types of cancers by swapping out different #mRNA sequences" !
#cytokines #antigens
https://scitechdaily.com/pancreatic-cancer-disappears-in-mice-after-new-mrna-immunotherapy/
https://www.europesays.com/ie/699020/ Daily vitamin C may benefit pre-cancerous blood disorder patients #blood #BloodCancer #cancer #CancerTreatment #Cell #ClinicalTrial #Cytokines #Éire #Epigenetics #Health #hospital #IE #Ireland #Leukemia #medicine #oral #pH #Placebo #Research #VitaminC #Wound #WoundHealing
https://www.europesays.com/ie/658579/ Maternal immune response to urinary tract infection may drive preterm birth risk #bacteria #Bacterial #Bladder #Cytokines #Éire #Health #IE #ImmuneResponse #Ireland #labor #medicine #Microbiology #Mortality #Pregnancy #Research #UrinaryTractInfection
https://www.europesays.com/ie/629518/ Integrated nanomaterials offer new strategies for cancer immunotherapy #Antigen #blood #BloodVessels #cancer #Cell #Cytokines #Éire #Gene #Health #IE #immunotherapy #Ireland #Manufacturing #oncology #Research #Tumor
Understanding the Common Cold: Why Fighting Off Illness Leaves Us Feeling Poorly
By: WPS News Health Correspondent
Baybay City | August 7, 2026
At the heart of the body’s reaction to a cold is the immune response. When a virus, such as a rhinovirus, enters our system, our immune system springs into action. White blood cells, including macrophages and lymphocytes, recognize these invaders and initiate a complex defense process. They release signaling molecules known as cytokines, which play a crucial role in communication between cells during the immune response.
The release of cytokines triggers inflammation, particularly in the respiratory tract. This inflammation results in symptoms like a sore throat, nasal congestion, and a persistent cough. Blood vessels become more permeable, allowing immune cells to reach the site of infection. While this response is vital for combating the virus, it often leads to the discomfort and malaise we associate with colds.
The release of cytokines triggers inflammation, particularly in the respiratory tract.
Additionally, the body demands more energy to mount a defense against the infection. This redirection of metabolic resources can leave individuals feeling weak and fatigued. Altered levels of neurotransmitters in the brain during this immune response can also contribute to feelings of lethargy and, at times, even mild depression.
The combination of mucus production, coughing, and general discomfort from inflammation results in symptoms like headaches and muscle aches. While these signs are indicative of the body’s work to eliminate the virus, they can make recovering from a cold a challenging experience.
In summary, the discomfort experienced during a cold is a direct result of the body’s immune response and the inflammatory processes it triggers. Understanding these mechanisms not only demystifies the experience but also highlights the importance of allowing our bodies the time and care they need to recover.
#coldSymptoms #commonCold #cytokines #fatigue #healthEducation #immuneResponse #inflammation #mucusProduction #PhilippinesHealth #recovery #respiratoryIllness #rhinovirus #seasonalIllness #wellBeing #whiteBloodCells
New visualization: Senescent Fibroblast Conditioned Media Accelerates Tumor Cell Motility
#CellularSenescence #SASP #TumorMicroenvironment #CancerCellMigration #DataVisualization #Oncology #Cytokines #SingleCellAnalysis
New Visualization: Age-Associated Rise in Circulating Pro-Inflammatory Signaling Molecules
I am sharing a grouped bar-style plot illustrating the phenomenon of inflammaging, the chronic, low-grade, sterile inflammatory state.
https://www.europesays.com/ie/590775/ Study reveals mechanism underlying HBV-induced liver inflammation #Antioxidant #Bases #carcinoma #Cell #CellBiology #Chronic #Cirrhosis #Cytokine #Cytokines #Éire #Gene #Genes #HBV #Health #Hepatitis #HepatitisB #HepatitisBVirus #HepatocellularCarcinoma #IE #inflammation #Ireland #Liver #medicine #OxidativeStress #Oxygen #Phosphorylation #Research #ResearchProject #Respiratory #Stress #Therapeutics #Transgenic #virus
https://www.europesays.com/fr/1037589/ Cancer de la prostate : cette nouvelle génération de médicaments avance « masquée » et suscite l’espoir #ActivateursDeLymphocytesT #CancerColorectal #CancerDeLaProstate #CancerDuPancréas #CancerDuPoumon #CancerMétastatique #Cytokines #FR #France #Health #immunothérapie #ImmunothérapieAnticancéreuse #InfectionChronique #LymphocytesT #MaladieVirale #Médicaments #metastase #RégressionTumorale #Santé #SystèmeImmunitaire #Toxicité
https://www.europesays.com/be-fr/160609/ Cancer de la prostate : cette nouvelle génération de médicaments avance « masquée » et suscite l’espoir #ActivateursDeLymphocytesT #BE #BEFr #Belgique #Belgium #CancerColorectal #CancerDeLaProstate #CancerDuPancréas #CancerDuPoumon #CancerMétastatique #Cytokines #Health #immunothérapie #ImmunothérapieAnticancéreuse #InfectionChronique #LymphocytesT #MaladieVirale #médicaments #Métastase #RégressionTumorale #Santé #SystèmeImmunitaire #toxicité
https://www.europesays.com/ch-fr/200021/ Cancer de la prostate : cette nouvelle génération de médicaments avance « masquée » et suscite l’espoir #ActivateursDeLymphocytesT #CancerColorectal #CancerDeLaProstate #CancerDuPancréas #CancerDuPoumon #CancerMétastatique #Cytokines #Health #Immunothérapie #ImmunothérapieAnticancéreuse #InfectionChronique #LymphocytesT #MaladieVirale #médicaments #metastase #RégressionTumorale #Santé #Suisse #SystèmeImmunitaire #toxicité
https://www.europesays.com/ie/559240/ Melatonin dampens fetal membrane inflammation linked to preterm birth #AntiInflammatory #Bacterial #CCL2 #CCL3 #CCL5 #Chemokine #Chemokines #Cytokine #Cytokines #Éire #ELISA #ExVivo #Gene #GeneExpression #Health #IE #inflammation #Ireland #labor #melatonin #Membrane #Mortality #Placenta #Pregnancy #Research #SignalingPathway #Sleep
Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission
Abstract Introduction: Cancer survivors display impaired quality of life and increased risk to develop cardiometabolic comorbidit…
#dining #cooking #diet #food #mediterranean #MediterraneanDiet #MediterraneanFood #cancer #Cytokines #LGCI #Lifestyle #Mediterranean
https://www.diningandcooking.com/2702442/unraveling-the-anti-inflammatory-effects-of-mediterranean-diet-in-patients-with-cancer-remission/
Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission
Abstract Introduction: Cancer survivors display impaired quality of life and increased risk to develop cardiometabolic comorbidities. Low-grade chronic inflammatio…
#dining #cooking #diet #food #MediterraneanDiet #cancer #Cytokines #LGCI #Lifestyle #Mediterranean
https://www.diningandcooking.com/2702442/unraveling-the-anti-inflammatory-effects-of-mediterranean-diet-in-patients-with-cancer-remission/
https://www.europesays.com/ie/529306/ Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration #Aging #Alzheimer'sDisease #blood #Brain #CentralNervousSystem #Chronic #Cytokines #DNA #DNADamage #Éire #Ganglion #Genes #gmp #Health #IE #immunity #inflammation #Interferon #Ireland #Kinase #NervousSystem #Neurodegeneration #NeurodegenerativeDisease #NeurodegenerativeDiseases #NucleicAcid #Parkinson'sDisease #Pathogen #Protein #Tumor #Tumorigenesis
Press Release: Sanofi’s lunsekimig met primary and key
Sanofi’s lunsekimig met primary and key secondary endpoints in phase 2 respiratory studies in asthma and CRSwNP The AIRCULES phase…
#France #FR #Europe #EU #Sanofi #asthma #asthme #clinicalresearch #Cytokines #essaiscliniques #health #inflammation #maladiesrespiratoires #Nanobody #ParisStockExchange:SAN #Pharmaceuticals #respiratorydisease #SanofiWinthropIndustrie #Santé
https://www.europesays.com/france/30955/
💁🏻♀️ TIL: Engineers at #RiceUniversity built a flexible patch containing engineered human #cells sealed in gel capsules.
The cells release healing #proteins called #cytokines directly at the injury site for days. In #mice and #pigs, treated wounds closed faster than untreated ones. The patch hasn’t been tested on #humans yet, but the approach could eventually help chronic wounds that won’t heal on their own.
👉 https://www.zmescience.com/science/living-bandage-heals-wounds/
#biology #medicine #bioengineering #science #research #diabetes
Mesenchymal drift may explain how aging cells lose their identity
A new review argues that aging may not be just a collection of molecular defects, but a progressive…
#NewsBeep #News #Science #Aging #AU #Australia #Cell #Chronic #Cytokines #dna #Embryogenesis #Fibroblast #Fibrosis #Genomic #Inflammation #Transcription #TranscriptionFactors
https://www.newsbeep.com/au/707805/
https://www.europesays.com/ie/485530/ Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity #cancer #CancerImmunotherapy #Cell #Cold #Cytokines #Éire #IE #ImmuneSystem #immunotherapy #Ireland #medicine #Nanoparticles #pH #Research #Science #Technology #Tumor
https://www.europesays.com/ie/458402/ Hepatitis C infection associated with reduced portal insulin levels #blood #Cytokines #Éire #Glucose #Health #Hepatitis #HepatitisC #Hepatology #IE #ImmuneResponse #ImmuneSystem #Insulin #InsulinResistance #Ireland #Liver #Metabolism #Research #virus
A single sauna session boosts immune cells within minutes
New research reveals how a brief Finnish sauna session mobilizes immune defenses within minutes, offering fresh clues into…
#NewsBeep #News #Health #AU #Australia #CardiovascularDisease #Cell #Cytokine #Cytokines #Dementia #Ear #GlobalHealth #heat #heatstress #Hemoglobin #Lymphocyte #neutrophils #Psychosis #research #Respiratory #stress
https://www.newsbeep.com/au/612848/
Cytokines Market in Poland | Report – IndexBox https://www.byteseu.com/1918811/ #BiomarkerDiscoveryAndValidation #BiopharmaMarketReport #CellCultureAndStemCellExpansion #Cytokines #forecast #HighThroughputProteinPurification #ImmunologyAndInflammationResearch #LyophilizationAndStabilization #mammalian #MarketAnalysis #MultiplexImmunoassayPlatforms #Poland #RecombinantProteinExpressionSystems(EColi #TherapeuticDevelopmentForAutoimmuneDiseasesAndCancer #Yeast
https://www.europesays.com/2895566/ Cytokines Market in Poland | Report – IndexBox #Aktualności #BiomarkerDiscoveryAndValidation #BiopharmaMarketReport #CellCultureAndStemCellExpansion #Cytokines #forecast #HighThroughputProteinPurification #ImmunologyAndInflammationResearch #LyophilizationAndStabilization #mammalian #MarketAnalysis #MultiplexImmunoassayPlatforms #poland #polska #RecombinantProteinExpressionSystems(EColi #TherapeuticDevelopmentForAutoimmuneDiseasesAndCancer #yeast
https://www.europesays.com/uk/870718/ Cytokines Market in France | Report – IndexBox #BiomarkerDiscoveryAndValidation #BiopharmaMarketReport #CellCultureAndStemCellExpansion #Cytokines #EU #Europe #Forecast #France #HighThroughputProteinPurification #ImmunologyAndInflammationResearch #LyophilizationAndStabilization #mammalian #MarketAnalysis #MultiplexImmunoassayPlatforms #RecombinantProteinExpressionSystems(EColi #TherapeuticDevelopmentForAutoimmuneDiseasesAndCancer #yeast
Cytokines Market in France | Report – IndexBox
This repor…
#France #FR #Europe #EU #Biomarkerdiscoveryandvalidation #biopharmamarketreport #Cellcultureandstemcellexpansion #Cytokines #forecast #High-throughputproteinpurification #Immunologyandinflammationresearch #Lyophilizationandstabilization #mammalian #marketanalysis #Multipleximmunoassayplatforms #Recombinantproteinexpressionsystems(E.coli #Therapeuticdevelopmentforautoimmunediseasesandcancer #yeast)
https://www.europesays.com/france/2405/
🧱 What if activation and inhibition are not about binding but about motion?
🔗 Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines
https://www.europesays.com/ie/381237/ Can eating almonds reduce inflammation in obesity? #Adipose #AntiInflammatory #appetite #CardiovascularDisease #Cell #Chronic #Cookies #Cytokine #Cytokines #diabetes #diet #Éire #Glucose #Health #IE #immunity #inflammation #Insulin #InsulinResistance #Interleukin #Ireland #Nutrients #Obesity #Protein #Type2Diabetes #Vegetables #VitaminE #WeightLoss
Post-doctoral fellowship -- B cell & antibody response in tuberculosis
New Jersey Medical School, Rutgers
See the full job description on jobRxiv: https://jobrxiv.org/job/new-jersey-medical-school-rutgers-27778-post-doctoral-fellowship-b-cell-antibody-response-in-tuberculosis/
#Antibody #antigenpresentation #bcells #cytokines #Inflammation #Science...
https://jobrxiv.org/job/new-jersey-medical-school-rutgers-27778-post-doctoral-fellowship-b-cell-antibody-response-in-tuberculosis/?fsp_sid=9993
Study reveals coffee triggers distinct cytokine responses compared with pure caffeine
A controlled human study reveals that coffee’s complex chemical matrix may shape immune responses differently than pure caffeine,…
#NewsBeep #News #Health #AU #Australia #Biomarker #Caffeine #Coffee #Cytokine #Cytokines #Interferon #Metabolism #Nutrition #Pharmacokinetics #Physiology #publichealth #research
https://www.newsbeep.com/au/489828/
Post-doctoral fellowship -- B cell & antibody response in tuberculosis
New Jersey Medical School, Rutgers
See the full job description on jobRxiv: https://jobrxiv.org/job/new-jersey-medical-school-rutgers-27778-post-doctoral-fellowship-b-cell-antibody-response-in-tuberculosis/
#Antibody #antigenpresentation #bcells #cytokines #Inflammation #Science...
https://jobrxiv.org/job/new-jersey-medical-school-rutgers-27778-post-doctoral-fellowship-b-cell-antibody-response-in-tuberculosis/?fsp_sid=9489
Too sick to socialize: How the brain and immune system promote staying in bed | MIT News
“I just can’t make it tonight. You have fun without me.” Across much of the animal kingdom, when…
#NewsBeep #News #Headlines #cytokines #dorsalraphenucleus(DRN) #GloriaChoi #IL-1R1 #IL-1β #Latvia #LiuYang #LV #MITBCS #MITPicowerInstitute #neuroimmuneinteractions #Neuroimmunology #sicknessbehavior #socialisolation
https://www.newsbeep.com/299645/
https://www.europesays.com/ie/224410/ Too sick to socialize: How the brain and immune system promote staying in bed | MIT News #Cytokines #DorsalRapheNucleus(DRN) #Éire #GloriaChoi #Health #IE #IL1R1 #IL1β #Ireland #LiuYang #MITBCS #MITPicowerInstitute #NeuroimmuneInteractions #Neuroimmunology #SicknessBehavior #SocialIsolation
Poor dietary iron weakens lung memory T cells after flu infection
Even when immune memory cells form in the lung after influenza infection, insufficient dietary iron leaves them less…
#NewsBeep #News #Health #Anemia #Antigen #AU #Australia #Blood #CD4 #Cell #Cytokine #Cytokines #Cytometry #diet #Digestion #Flowcytometry #flu #immunity #Immunology #influenza #irondeficiency #Liver #Lungs #Nutrition #Proliferation #Receptor
https://www.newsbeep.com/au/335958/
https://www.europesays.com/ie/141703/ How COVID mRNA vaccines may make cancer treatments more effective #cancer #Cell #Cold #CoronavirusDiseaseCOVID19 #Covid19 #Cytokines #Éire #Health #heat #IE #ImmuneSystem #immunotherapy #Interferon #Ireland #LungCancer #Melanoma #NonSmallCellLungCancer #PDL1 #Preclinical #Receptor #SARS #SarsCov2 #skin #SmallCellLungCancer #therapy #Tumor #Vaccine
The co-regulation of HPV infection by vaginal microbiota and the immune system | Virology Journal
Mirghani H, Amen F, Tao YG, et al. Increased radiosensitivity of HPV-positive head and neck cancers: molecular basis…
#NewsBeep #News #Health #AU #Australia #Cytokines #Humanpapillomavirus #Immunomodulation #Inflammation #Vaginalmicrobiota #Virology
https://www.newsbeep.com/au/220596/
Mitochondria, Mind, and Metabolism: The Interoceptive Frontier
#Mitochondria #Mitoception #Allostasis #Interoception #MitochondrialMedicine #EnergyMetabolism #StressResponse #PersonalizedMedicine #BrainBodyConnection #Cytokines #ATP #Angiogenesis
How Your Immune System and Brain Communicate: The Hidden Connection
#ImmuneSystem #BrainHealth #Microglia #Inflammation #MentalHealth #Cytokines #StressAndMood #Neuroscience #InflammationAndDepression #Neuroimmunology
Overuse injuries spark lasting pain and mood changes through inflammation, rat study finds
New research uncovers how repetitive strain injuries ignite an inflammatory storm, driving both pain and social withdrawal, offering…
#NewsBeep #News #Health #AU #Australia #Blood #Brain #Chronic #Chronicpain #Cytokines #depression #Fatigue #food #Hypersensitivity #Inflammation #Interleukin #Interleukin-6 #Musculoskeletal #Nerve #Pain #Physiology #research
https://www.newsbeep.com/au/9950/
The Brain’s Immune System: Microglia and Inflammation Explained
#BrainScience #Neuroscience #GlialCells #Microglia #Astrocytes #Neuroinflammation #BrainHealth #Neurodegeneration #Demyelination #Cytokines #Neurons #BrainResearch #Neurobiology #BrainInjury #BrainRecovery
The Intricate Web of Stress: Exploring Your Body’s Response Systems
#StressResponse #Neuroscience #ImmuneSystem #Neuroendocrine #Cytokines #MentalHealth #HealthScience #FightOrFlight #StressManagement #BrainAndBody
Cracking Joints and Neurological Health: Unveiling the Hidden Connections
#HumanBiology #JointHealth #Neuroscience #Inflammation #SynovialFluid #GlialCells #Cytokines #Neuroinflammation #NeuroscienceExplained #MedicalScience #HealthAndWellness #BiologyInsights #BrainHealth #InflammatoryResponse #MedicalEducation
Ultrasonic vibrations, transmitted to killer T cells via micro bubbles, trigger a 3.6 fold greater release of tumor killing proteins from the T cells. #ultrasound #cancer #microbuttles #tcells #cytokines
https://www.instagram.com/p/DF_E2emOYkR/
The Body Metropolis: An Epic Battle of Superheroes and Supervillains Within Us
#BodyMetropolis #ImmuneSuperheroes #Cytokines #Pathophysiology #DiseaseProgression #CellularNetworks #Cytotoxicity #ScienceIsCool #HealthInnovation #EpicBiology #InnerBattles #ImmuneSystem #SciFiInRealLife
Brain inflammation may be the reason behind muscle fatigue after infection and injury https://www.psypost.org/brain-inflammation-may-be-the-reason-behind-muscle-fatigue-after-infection-and-injury/?utm_source=dlvr.it&utm_medium=mastodon #Neuroinflammation #MuscleFatigue #BrainHealth #ChronicDisease #Cytokines
Immunological #findings of West Caucasian #bat #virus in an accidental host http://biorxiv.org/cgi/content/short/2024.09.12.612599v1?rss=1
In #hamsters, #WCBV was highly pathogenic, determining 100% #lethality and mild #encephalitis. In comparison with Duvenhage virus (DUVV) and #RABV, we found that WCBV displayed an intermediate ability to promote cellular antiviral response, produce pro-inflammatory #cytokines, recruit and activate #lymphocytes in the hamsters central nervous system.
An ex vivo #human precision-cut #lung slice #platform provides insight into #SARS-CoV-2 #pathogenesis and #antiviral drug #efficacy, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00794-24?af=R
We identified early induction of specific #cytokines, especially IP-10 and IL-8, as potential predictors for severe #COVID19, & uncovered a hitherto unrecognized phenomenon that while infectious virus disappears at late times of infection, viral #RNA persists and lung histopathology commences.
#Australian researchers have found that a family of #proinflammatory #molecules called beta common #cytokines control inflammation and scarring of the airways (fibrosis) in severe and steroid-resistant #asthma.
#Medical #sflorg
https://www.sflorg.com/2024/02/med02252402.html
Please find below our most recent pre-print. We studied the role of the RNA binding protein ZFP36L2 in effector T cells and found how it regulated the production of IFNgamma in late T cell responses and continuous activation with tumor cells (in vitro/in vivo). Happy reading!
https://www.biorxiv.org/content/10.1101/2024.02.09.579641v1.article-metrics
#Myokines are #cytokines and other #peptides that are produced, expressed, and released by #muscle fibers and exert either autocrine, paracrine, or #endocrine effects. They mediate communication between muscle and other organs, including the brain, adipose tissue, bone, liver, gut, pancreas, vascular bed, and skin. (1/6)
How does signaling via extracellular #nucleotides contribute to innate immunity? Systematic #P2Y receptor survey in human #macrophages shows some control #inflammatory #cytokines, others viral replication, and #P2Y11 uniquely combining both roles
Line Lykke Andersen et al Andreas Pichlmair
By @harryspoelstra COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory #cytokines/SGLT2 pro-oxidant pathway
❗Finally we’re getting closer to understanding the underlying mechanisms, maybe even finding therapeutic possibilities, that of course need further research!
➡️"In #COVID19 patients, pro-inflammatory cytokines( f IL-1β, IL-6, TNF-α, MCP-1 and sICAM-1) induced a redox-sensitive up regulation of…
➡️Http://pubmed.ncbi.nlm.nih.gov/37797691/
How does breast cancer recur after dormancy? @TTCooperPhD & @DrPostovit explore a #PLOSBiology study showing that #docetaxel-induced injury of #tumor stromal cells stimulates release of #cytokines that support dormancy escape of #BreastCancer cells. Paper: https://plos.io/3RjsGoQ Primer: https://plos.io/457Epuh
@gpollara @JExpMed Intriguing. In an earlier postdoc position I had a look at #DendriticCells, and especially the #cDC1 were abundant, but seemed to be just sitting in the inflammatory environment, doing little. One of the very abundant cytokines: #IL6
We also looked at the effect of that and other #cytokines, but mostly on #Tcells, among others due to the low abundance of cDC1 in HC blood to be able to do many in vitro experiments.
Healing from the hypothalamus –
To survive an infection, our body must recognize and respond to invading pathogens. This is the job of the immune system. When the first few immune cells encounter a pathogen, especially one that they haven’t seen before, they start releasing #cytokines like #interleukin-1 (IL-1).
These cytokines are the messengers of the immune system. They race through the body via the bloodstream, summoning immune troops to push back the invading pathogen.
When they reach the central nervous system, cytokines must cross the #blood-#brain #barrier to alert and recruit a brain response. The blood-brain barrier has only a handful of entry points, called #circumventricular #organs, where traffic can pass between the central nervous system and the bloodstream with relative ease.
One of these sits at the base of the #hypothalamus in a structure called the #Vascular #Organ of the #Lamina #Terminalis (VOLT for short). The #VOLT is filled with receptors that detect IL-1 and other cytokines.
That, along with its proximity to our #homeostat hypothalamus, means it’s positioned perfectly to sense an ongoing immune response and initiate our brain and body’s many defensive tactics.
After receiving signals from the VOLT, the hypothalamus creates many of the familiar experiences of sickness
https://pennneuroknow.com/2023/06/27/healing-from-the-hypothalamus/
“Researchers have shown that the inflammatory molecule IL-17 has a key function in skin aging. The study was published in Nature Genetics by a team of researchers from the Institute for Research in Biomedicine (IRB Barcelona) working alongside the National Center for Genomic Analysis (CNAG).” #dna #epigenetics #aging #cytokines #geneadons #isogg https://www.technologynetworks.com/immunology/news/blocking-inflammatory-protein-may-delay-skin-aging-374600
July 2022: #Glyphosate infiltrates the #brain and increases pro-#inflammatory cytokine TNFα: implications for neurodegenerative disorders
"#Herbicides are environmental contaminants that have gained much attention due to the potential hazards they pose to human health. Glyphosate, the active ingredient in many commercial herbicides, is the most heavily applied herbicide worldwide. The recent rise in glyphosate application to #corn and #soy crops correlates positively with increased death rates due to Alzheimer’s disease and other #neurodegenerative disorders. Glyphosate has been shown to cross the blood–brain barrier in in vitro models, but has yet to be verified in vivo. Additionally, reports have shown that glyphosate exposure increases pro-inflammatory #cytokines in blood plasma, particularly #TNFα disorders."
Read more:
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-022-02544-5
Very pleased to see our paper is now in print:
Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function https://www.cell.com/cell-reports/fulltext/S2211-1247%2823%2900430-8
here we show how RNA binding proteins regulate the magnitude and timing of cytokine expression in human T cells. and how the identified RBPs act a different time points and through different mechansism. The wonder world of RNA...
#RNA #RBPs #Immunology #Tcells #cytokines #regulation #proteomics
Lucie Descamps showed her work on droplet #microfluidics combined with #immunoassay detection of #cytokines.