#astrocytes — Public Fediverse posts

🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.

Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.

🌍 https://doi.org/10.1038/s41467-026-73435-z

#Neuroscience #Astrocytes #Neurobiology #NeuralDynamics

Understanding Brain Trauma: Cellular Responses and Molecular Cascades

#BrainInjury #Neuroinflammation #TraumaticBrainInjury #Microglia #Astrocytes #BloodBrainBarrier #Neuroregeneration #BrainHealth #Neuroscience #BrainRecovery

https://youtube.com/shorts/HyozNFxpwxg?feature=share

Tryptophan and the Kynurenine Pathway: Metabolic Routes Impacting Mood and Neurodegeneration

#BrainChemistry #Neuroimmune #KynureninePathway #GutBrainAxis #Neuroinflammation #Microglia #Astrocytes #Neurodegeneration #OxidativeStress #MentalHealth #BrainHealth #Metabolism #NervousSystem #DietAndBrain #Neuroscience

https://youtube.com/shorts/boyH2vLgGow?feature=share

Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:

🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8

#CompNeuro #Neuroscience

#Astrocytes are generally depicted as #Parenchymal somas with processes reaching the #bloodvessels. Here, I show that #AstrocyteSoma are part of the #Endfeet around #PenetratingArterioles and #AscendingVenules (9/15)

Mouse studies cast astrocytes as stars of sensory perception

https://www.spectrumnews.org/news/mouse-studies-cast-astrocytes-as-stars-of-sensory-perception/

#inhibitorysignaling #sensoryperception #fragileXsyndrome #geneexpression #mousemodels #astrocytes #seizures #synapses #hearing #autism #touch #News #FMR1 #GABA