#demyelination — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #demyelination, aggregated by home.social.
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The combination of dasatinib (a leukemia treatment) and quercertin (a common polyphenol found in vegetables) remove senescent cells and is being studied as an anti-aging treatment. A new mouse study finds that the combination reduces the myelin sheath around nerve cells, causing neuropathology in the brain.
Summary: https://www.sciencealert.com/promising-anti-aging-drug-may-cause-brain-damage-scientists-warn
Original paper (not open access): https://www.pnas.org/doi/10.1073/pnas.2524897123
#Science #Aging #Dasatanib #Quercertin #Demyelination #BrainDamage
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What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @PLOSBiology https://plos.io/4mI4lVO
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The Brain’s Immune System: Microglia and Inflammation Explained
#BrainScience #Neuroscience #GlialCells #Microglia #Astrocytes #Neuroinflammation #BrainHealth #Neurodegeneration #Demyelination #Cytokines #Neurons #BrainResearch #Neurobiology #BrainInjury #BrainRecovery
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Chronic #trypanosome brain infection induces meningeal responses resulting in ectopic lymphoid aggregates containing #autoreactiveBcells; #autoantigens include MBP, consistent with experimentally observed #demyelination @Jquintanalcala &co #PLOSBiology https://plos.io/3R8xgpH
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@CastlTrAstonDrs Thank you for mentioning this great study!
My vision deteriorated for several months after my 2nd Covid infection, and my eyes hurt when watching from left to right. After reading this article and looking certain things up, I think it must have been neuritis optica!
Mind you, after my first infection I got all sorts of B12-deficiency symptoms, which made me suspect that there was a demyelinating process going on.
1/n
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Injecting fractalkine into mouse models of multiple sclerosis increased the number of oligodendrocytes. Findings suggest fractalkine may help to slow the progression, or potentially halt Multiple Sclerosis.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neuroimmunology #Neuroinflammation #Demyelination #DemyelinatingDiseases #MultipleSclerosis #Oligodendrocytes #Fractalkine
https://neurosciencenews.com/multiple-sclerosis-fractslkine-222344/