Live and recent posts from across the Fediverse tagged #neurologicaldiseases, aggregated by home.social.
Watch the new close-up episode as #DoctoralResearcher Nina Miller visits the SyNergy Cluster of Excellence, where researchers are exploring the causes of #NeurologicalDiseases and developing new #TherapeuticApproaches: https://youtu.be/METIE2bAp9s
📹ProLehre, CCC
https://www.europesays.com/people/235333/ Elon Musk’s Neuralink Brain Implant Helps Speech-Impaired Man Speak First Words #ALSCommunication #AmyotrophicLateralSclerosis #BrainImplant #BrainSignalsDecoding #BrainComputerInterface #ElonMusk #Musk #N1Implant #Neuralink #NeurologicalDiseases #SpeechImpairment #ThoughtToSpeech #VOICETrial
https://www.europesays.com/ch/113083/ Roche’s $2.3 Billion Nurix Deal Sends Shares Moving #BloodCancers #GuruFocus #NeurologicalDiseases #NurixTherapeutics #Roche #RocheHoldingAG
Euthanasia cases in Spain will increase by 32.6% in 2025
According to data presented by the Ministry of Health, 565 eut…
#Spain #ES #Europe #Europa #EU #BasqueCountry #bioethics #BioethicsObservatory #catalonia #CATHOLICUNIVERSITYOFVALENCIA #ESTERBOSCH #Euthanasiadata2025 #euthanasiainSpain #euthanasialaw #Euthanasiarequests #JULIOTUDELA #MinistryofHealth #navarre #Neurologicaldiseases #Noeliaeuthanasia #Oncologicalpathologies #palliative-care #Trending
https://www.europesays.com/spain/48183/
Euthanasia cases in Spain will increase by 32.6% in 2025 https://www.byteseu.com/2154224/ #BasqueCountry #bioethics #BioethicsObservatory #Catalonia #CATHOLICUNIVERSITYOFVALENCIA #ESTERBOSCH #EuthanasiaData2025 #EuthanasiaInSpain #EuthanasiaLaw #EuthanasiaRequests #JULIOTUDELA #MinistryOfHealth #Navarre #NeurologicalDiseases #NoeliaEuthanasia #OncologicalPathologies #PalliativeCare #Spain #trending
PepGen Announces Topline Results from Lowest Dose (5 mg/kg) MAD Cohort in the Ongoing Phase 2 FREEDOM2 Study Demonstrating Favorable Safety, Splicing and vHOT Data
– PGN-EDODM1 was generally well-tolerated with all adverse events mild or moderate and no serious adverse events reported…
#NewsBeep #News #Medication #CA #Canada #clinicalresults #FREEDOM2 #Health #neurologicaldiseases #oligonucleotide #patients #PepGen #RNAsplicing #TheCompany
https://www.newsbeep.com/ca/575804/
https://www.europesays.com/ie/?p=415382 PepGen Announces Topline Results from Lowest Dose (5 mg/kg) MAD Cohort in the Ongoing Phase 2 FREEDOM2 Study Demonstrating Favorable Safety, Splicing and vHOT Data #ClinicalResults #Éire #FREEDOM2 #Health #IE #Ireland #Medication #NeurologicalDiseases #Oligonucleotide #patients #PepGen #RNASplicing #TheCompany
PepGen Announces Topline Results from Lowest Dose (5 mg/kg) MAD Cohort in the Ongoing Phase 2 FREEDOM2 Study Demonstrating Favorable Safety, Splicing and vHOT Data
– PGN-EDODM1 was generally well-tolerated with all adverse events mild or moderate and no serious adverse events reported…
#NewsBeep #News #Medication #clinicalresults #FREEDOM2 #Health #neurologicaldiseases #oligonucleotide #Patients #PepGen #RNAsplicing #TheCompany #UK #UnitedKingdom
https://www.newsbeep.com/uk/507180/
Blood test breakthrough could transform ALS detection and care
A new study may finally change how amyotrophic lateral sclerosis (ALS) is diagnosed. Scientists from UCLA Health and…
#NewsBeep #News #Health #AU #Australia #BloodTest #DNAMethylation #GenomeMedicine #neurologicaldiseases #test #UCLAHealth #UniversityofQueensland
https://www.newsbeep.com/au/224064/
This Haiti-Born Doctor Built A $6 Billion Business Developing Drugs For Depression And Alzheimer’s https://www.byteseu.com/1410095/ #$AXSM #ADHD #Alzheimer'sDiseaseAgitation #AxsomeTherapeutics #billionaires #BiotechFounder #business #depression #HerriotTabuteau #ImmigrantFounders #NeurologicalDiseases
https://www.europesays.com/uk/239957/ Tiny quantum sensor breaks noise limits, could boost MRI, space tech #AtomicSpinEnsemble #GravitationalWaves #InventionsAndMachines #MRI #NeurologicalDiseases #OpticsBasedSensors #Physics #QuantumSensing #QuantumSensors #Science #UK #UnitedKingdom
Interested in researching #neurogenetics with a supportive environment? We at University of Leicester
have several exciting #PhD projects to study #Evolution, #neurologicaldiseases, #epigenetic, #ageing, #sleep and meal insects biology
Please see details in following link and apply, BOOST welcome!
@Javier_DN Is it true that in societies where big families -sometimes 4 generations- live together, Alzheimers disease is less prevalent?
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health
Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study
Social isolation contributes to human brain atrophy and cognitive decline, indicating an opportunity to reduce dementia risk by promoting social networks.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health
Social Bonds Protect Aging Brains
Social isolation can potentially harm brain structure and cognitive performance, suggesting an increased risk of conditions like Alzheimer’s dementia.
A lack of quality social interaction can lead to a decrease in the hippocampus’s volume, crucial for memory formation and retrieval, and poorer cognitive performance.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer
#CognitiveDecline #CognitiveDysfunction #Dementia #Hippocampus #Neuroimaging #NeuroImage #SocialIsolation #SocialBond
#Biomedicine #Health
https://neurosciencenews.com/social-aging-neuroscience-brain-23505/
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
Aβ was associated with increased plasma phosphorylated tau only in individuals positive for astrocyte reactivity (Ast+).
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #BetaAmyloid #AmyloidPlaques #Tau #NeurofibrillaryTangles #ReactiveAstrocytes #Astrocytes #Glia #GFAP #Biomarker #Alzheimer #Biomedicine #Health
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
Therapeutic Strategies for Spinocerebellar Ataxia Type 1 (SCA1)
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #SpinocerebellarAtaxia #SCA1 #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics
#Genetics #HereditaryDiseases #GeneticDiseases
#Biomedicine #Health
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases.
Friedreich’s ataxia represents a test case to validate the potential of therapeutic strategies based on nanoparticles.
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics
#Genetics #HereditaryDiseases #GeneticDiseases
#ClinicalTrial
#GeneTherapy
#Neuroinflammation
#Mitochondria #MitochondrialDysfunction
#Nanoparticles #Nanomedicine #Nanobiotechnology
#Biomedicine #Health
https://academic.oup.com/brain/article/doi/10.1093/brain/awad014/7024724
APOE expression and secretion are modulated by mitochondrial dysfunction
This study presents compelling evidence that ApoE is upregulated in various models of mitochondrial respiratory chain dysfunction. The work is of fundamental interest for those studying neurodegeneration and the role of ApoE in Alzheimer's disease; future work will be needed to reveal the molecular basis of this dramatic phenotype.
#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #ApoE #Neurogenetics #Mitochondria #MitochondrialDysfunction
Vatiquinone found to slow Friedreich's Ataxia progression by 75% after 1.5 years
But oral therapy fails to meet primary goal in Phase 2/3 trial
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics
#Genetics #HereditaryDiseases #GeneticDiseases
#ClinicalTrial
#Vatiquinone #Neuroinflammation
#Biomedicine #Health
https://friedreichsataxianews.com/news/vatiquinone-slows-fa-progression-after-18-months-trial-data/
Running throughout Middle-Age Keeps Old Adult-Born Neurons Wired
Long-term running maintains the wiring of “old” new neurons, born during early adulthood, within a network that is important for memory function during aging in mice.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neurogenesis #Neuron #BrainAging #Aging #MemoryLoss #CognitiveDecline #CognitiveDysfunction #PhysicalActivity #PhysicalExercise #Running
Running Rewires the Aging Brain: Exercise Protects Memory Function
Physical activity, particularly running, has been found to rewire aging brains, helping to preserve memory functions.
Long-term running keeps older neurons wired, potentially preventing age-related memory loss and neurodegeneration.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neurogenesis #Neuron #BrainAging #Aging #MemoryLoss #CognitiveDecline #CognitiveDysfunction #PhysicalActivity #PhysicalExercise #Running
https://neurosciencenews.com/running-neurogenesis-aging-23339/
Short-read genome sequencing test may help diagnose atypical Friedreich's Ataxia
Test advised for patients whose symptoms, family history are not indicative of Friedreich's Ataxia.
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics
Higher Vitamin D Dose in Childhood Linked to Lower Mental Health Risk
A recent study suggests higher doses of Vitamin D3 supplementation during early childhood may reduce the risk of internalizing psychiatric symptoms in later years.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Psychiatry #PsychiatricDiseases #NeuropsychiatricDiseases #MentalHealth #VitaminD #VitaminD3 #BrainDevelopment
https://neurosciencenews.com/mental-health-child-vitamin-d-23316/
The Therapeutic Potential of Non-Invasive and Invasive Cerebellar Stimulation Techniques in Hereditary Ataxias
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics #CerebellarStimulation #DeepBrainStimulation #TranscranealDirectStimulation #Neurotechnology #Biomedicine
Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
The male remained cognitively intact until 67 years of age despite carrying a PSEN1-E280A mutation. He had extremely elevated amyloid plaque burden and limited entorhinal Tau tangle burden.
He was heterozygous for a rare variant in RELN showing stronger ability to reduce human Tau phosphorylation in a knockin mouse.
#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Tau #Reelin #ApoE #Dementia #Neurogenetics
Halting Alzheimer’s Progression: Synapses Transport Toxic Proteins
A new study uncovers how synapses transport toxic tau protein oligomers, contributing to Alzheimer's progression. This discovery paves the way for strategies to halt disease progression, a beacon of hope for Alzheimer's patients.
#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Tau #Synapses
Genes reveal surprising overlaps in brain diseases and disorders
Scientists find patterns in how disease-related genes switch on in the brain.
The study authors say this way of sorting brain diseases and psychiatric disorders could potentially identify new targets for treatments.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Psychiatry #PsychiatricDiseases #MentalDiseases #NeurodegenerativeDiseases #Neurodegeneration #BrainDiseases #NeurogeneticDiseases #Neurogenetics #Transcriptome #Transcriptomics #Genomics #MolecularBiology #Biomedicine
https://alleninstitute.org/news/genes-reveal-surprising-overlaps-in-brain-diseases-and-disorders/
A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases
Analysis of 40 common human brain diseases identifies 5 major transcriptional patterns, representing tumor-related, neurodegenerative, psychiatric and substance abuse, and 2 mixed groups of diseases affecting basal ganglia and hypothalamus.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Psychiatry #PsychiatricDiseases #MentalDiseases #NeurodegenerativeDiseases #Neurodegeneration #NeurogeneticDiseases #Neurogenetics #Transcriptome #Transcriptomics #Genomics #MolecularBiology #Biomedicine
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002058
In situ continuous Dopa supply by responsive artificial enzyme for the treatment of Parkinson’s disease
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Parkinson #DOPA #FunctionalNucleicAcid #ArtificialEnzyme #Enzyme #Biotechnology #Biomedicine
An in vivo neuroimmune organoid model to study human microglia phenotypes
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #BrainOrganoid #Organoid #NeuroimmuneOrganoid
#Microglia #Neuroimmune #Neuroimmunology
Human Brain Organoids Reveal How Microglia Develop and Function
Researchers have developed human brain organoids that contain microglia, the immune cells of the brain.
The researchers found that microglia are influenced by the environment in which they develop and that they play a role in both development and disease.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #BrainOrganoid #Organoid
#Microglia #Neuroimmune #Neuroimmunology
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer’s disease brains
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Aβ #AβFibrils #Immunotherapy #Lecanemab
Alzheimer’s Drug Lecanemab Shields Brain from Free-Roaming Amyloid Fibrils
Amyloid beta protein forms small aggregates that disrupt brain function in Alzheimer’s disease.
Lecanemab, a recently FDA-approved Alzheimer’s treatment, can neutralize these disruptive aggregates, hinting at its potential to slow down the disease’s cognitive decline.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #CognitiveDecline #CognitiveDysfunction #MemoryLoss #BetaAmyloid #AmyloidFibrils #Immunotherapy #Lecanemab
https://neurosciencenews.com/amyloid-fibril-neuropharmacology-23207/
Adenosine Improves Mitochondrial Function and Biogenesis in Friedreich’s Ataxia Fibroblasts Following L-Buthionine Sulfoximine-Induced Oxidative Stress
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #PatientFibroblasts #Adenosine #Mitochondria #MitochondrialDysfunction #MitochondrialBiogenesis #GeneActivity #OxidativeStress
Adenosine able to boost function of mitochondria in Friedreich's Ataxia cell study
Molecule could serve promising role in breakthrough treatments
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #PatientFibroblasts #Adenosine #Mitochondria #MitochondrialDysfunction
https://friedreichsataxianews.com/news/adenosine-boost-mitochondria-function-cell-study-promising/
Gene abnormality in Friedreich's Ataxia muscle cells is a ‘double hit’: Study
Reduced activity in genes needed for mitochondrial function, higher repressor gene activity
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #Muscle #Transcriptomics #GeneActivity #Mitochondria #MitochondriaDysfunction
https://friedreichsataxianews.com/news/gene-abnormality-fa-muscle-cells-is-double-hit-study/
Recommendations for Responsible Development and Application of Neurotechnologies
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Neurotechnology #Neuroimaging #BrainRecording #BrainActivity #BrainComputerInterface #BCI #MindReading #ArtificialIntelligence #AI #NeuroEthics #NeuroRights
A.I. Is Getting Better at Mind-Reading
In a recent experiment, researchers used large language models to translate brain activity into words.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Neurotechnology #Neuroimaging #BrainRecording #BrainActivity #BrainComputerInterface #BCI #SemanticReconstruction #Language #MindReading #ArtificialIntelligence #AI
https://www.nytimes.com/2023/05/01/science/ai-speech-language.html
Imaging Study Implicates Reactive Astrocyte-Neuron Interaction in Alzheimer’s Cognitive Decline
PET imaging with 11C-acetate and 18F-FDG was used to visualize the reactive astrocyte-induced acetate hypermetabolism and associated neuronal glucose hypometabolism in brains with neuroinflammation and Alzheimer’s Disease.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Astrocyte #Neuron #Alzheimer #BrainImaging #Neuroimaging #NeuroMetabolism #AcetateHypermetabolism #GlucoseHypometabolism #NeuroInflammation #CognitiveDecline #CognitiveDysfunction
Long COVID Smell Loss Linked to Changes in the Brain
Anosmia, or the loss of the sense of smell caused by long COVID is linked to changes in the brain that prevents correct olfactory processing.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Olfaction #Smell #Anosmia #Covid #LongCovid
A cellular taxonomy of the adult human spinal cord
Single-nucleus RNA sequencing and spatial transcriptomics of adult human spinal cord
#Neuroscience #SpinalCord #Neuron #Motoneuron #MotoneuronDisease #ALS #NeurodegenerativeDiseases #NeurologicalDiseases #Transcriptomics
Obesity-Related Neurodegeneration Mimics Alzheimer’s Disease
A new study led by scientists at The Neuro (Montreal Neurological Institute-Hospital) of McGill University finds a correlation between neurodegeneration in obese people and Alzheimer’s disease (AD) patients, suggesting that losing excess weight could slow cognitive decline in aging and lower risk for AD.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Aging #BrainAging #Obesity
https://neurosciencenews.com/obesity-neurodegeneration-alzheimers-22412/
Prenatal Pollution Exposure Linked to Lower Cognitive Scores in Early Life
Maternal exposure to air pollution during mid-to-late pregnancy was associated with lower scores on tests of cognition, language, and motor skills in children at the age of two.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodevelopmentalDisorders #Neurodevelopment #BrainDevelopment #Cognition
#Pollution #EnvironmentalHealth #OneHealth
https://neurosciencenews.com/pollution-pregnancy-cognition-22364/
Could a Viral Illness Increase Chances of Developing Alzheimer’s or Other Neurodegenerative Disease?
Study reveals a significant association between certain viral illnesses, including viral encephalitis and pneumonia-causing flu with an increased risk of developing a neurodegenerative disorder later in life. Researchers say existing vaccines against the viruses may reduce the chances of developing neurodegeneration.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Parkinson #ALS #Neurovirology #Encephalitis #Flu #Virology #Viruses #Vaccines
https://neurosciencenews.com/neurodegeneration-viral-infection-22356/
Common levels of pollution from traffic can impair brain function within a matter of hours, a new study reports. Just two hours of exposure to diesel exhaust impairs functional connectivity in the brain.
#Neuroscience #Brain #Neurology #NeurologicalDiseases #Pollution #EnvironmentalHealth #OneHealth
https://neurosciencenews.com/air-pollution-functional-connectivity-22355/
High Fat Diet Activates Early Inflammation in Mouse Brains, Supports Link to Neurological Disease
High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.
#Neuroscience #Neurology #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Inflammation #Metabolism #MetabolicDysfunction #Diabetes #Alzheimer #CognitiveImpairment #Diet #HighFatDiet
https://neurosciencenews.com/high-fat-diet-inflammation-neurodegeneration-22275/
Autopsy tissue samples of 44 people who died of COVID-19 showed SAR-CoV-2 virus spread throughout the body and to the brain, with traces of the virus lingering for 8 months.
#Neuroscience #Neurology #NeurologicalDiseases #Brain #BrainDiseases #Neurovirology #Virology #COVID-19
Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension
#Neuroscience #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Brain #Cerebellum #RareDiseases #GeneticDiseases #FriedreichAtaxia #Ataxia
https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29286