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#innateimmunity — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #innateimmunity, aggregated by home.social.

  1. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  2. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  3. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  4. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  5. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  6. #SARSCoV2 suppresses #InnateImmunity via multiple proteins, but what are their relative roles during infection? This study of a panel of 12 viral proteins shows that they (and especially NSP1 & NSP15) act via distinct yet redundant mechanisms @PLOSBiology plos.io/3Rptk6r

  7. #SARSCoV2 suppresses #InnateImmunity via multiple proteins, but what are their relative roles during infection? This study of a panel of 12 viral proteins shows that they (and especially NSP1 & NSP15) act via distinct yet redundant mechanisms @PLOSBiology plos.io/3Rptk6r

  8. #SARSCoV2 suppresses #InnateImmunity via multiple proteins, but what are their relative roles during infection? This study of a panel of 12 viral proteins shows that they (and especially NSP1 & NSP15) act via distinct yet redundant mechanisms @PLOSBiology plos.io/3Rptk6r

  9. #SARSCoV2 suppresses #InnateImmunity via multiple proteins, but what are their relative roles during infection? This study of a panel of 12 viral proteins shows that they (and especially NSP1 & NSP15) act via distinct yet redundant mechanisms @PLOSBiology plos.io/3Rptk6r

  10. #SARSCoV2 suppresses #InnateImmunity via multiple proteins, but what are their relative roles during infection? This study of a panel of 12 viral proteins shows that they (and especially NSP1 & NSP15) act via distinct yet redundant mechanisms @PLOSBiology plos.io/3Rptk6r

  11. Cytosolic viral RNA is detected by #antiviral #PatternRecognition receptors like RIG-I. This study shows that #Mediator subunit MED23 limits RIG-I expression via FOXO3, dampening #InnateImmunity & highlighting MED23 as a potential therapeutic target @PLOSBiology plos.io/457VwOe

  12. Cytosolic viral RNA is detected by #antiviral #PatternRecognition receptors like RIG-I. This study shows that #Mediator subunit MED23 limits RIG-I expression via FOXO3, dampening #InnateImmunity & highlighting MED23 as a potential therapeutic target @PLOSBiology plos.io/457VwOe

  13. Cytosolic viral RNA is detected by #antiviral #PatternRecognition receptors like RIG-I. This study shows that #Mediator subunit MED23 limits RIG-I expression via FOXO3, dampening #InnateImmunity & highlighting MED23 as a potential therapeutic target @PLOSBiology plos.io/457VwOe

  14. Cytosolic viral RNA is detected by #antiviral #PatternRecognition receptors like RIG-I. This study shows that #Mediator subunit MED23 limits RIG-I expression via FOXO3, dampening #InnateImmunity & highlighting MED23 as a potential therapeutic target @PLOSBiology plos.io/457VwOe

  15. Cytosolic viral RNA is detected by #antiviral #PatternRecognition receptors like RIG-I. This study shows that #Mediator subunit MED23 limits RIG-I expression via FOXO3, dampening #InnateImmunity & highlighting MED23 as a potential therapeutic target @PLOSBiology plos.io/457VwOe

  16. #InnateImmunity is a crucial surveillance framework. However, @Colombani explores 2 @PLOSBiology studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth. Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

  17. #InnateImmunity is a crucial surveillance framework. However, @Colombani explores 2 @PLOSBiology studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth. Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

  18. #InnateImmunity is a crucial surveillance framework. However, @Colombani explores 2 @PLOSBiology studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth. Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

  19. #InnateImmunity is a crucial surveillance framework. However, @Colombani explores 2 @PLOSBiology studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth. Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

  20. #InnateImmunity is a crucial surveillance framework. However, @Colombani explores 2 @PLOSBiology studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth. Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0

  21. New study! Learning about inflammation by studying the differences between mammals – a toot-orial.

    doi.org/10.1186/s10020-024-010

    When the body meets an infectious microbe or similar challenge it activates an inflammatory cascade. Inflammation helps eliminate the microbe, but, if it gets of control, it can be dangerous or even fatal.

    We like to assume that inflammation is basically the same for all animals. And this is usually true in cell culture, but in vivo …

    #Inflammation #InnateImmunity

    1/

  22. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  23. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  24. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  25. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  26. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  27. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  28. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20