#alzheimers — Public Fediverse posts

‘I want to do everything I can to head off dementia’: why demand for the shingles vaccine is soaring
By Ian Sample Science editor

Could a drug intended to prevent painful rashes also protect our brains as we get older? The signs are promising – but not conclusive. Yet that’s enough to be driving a boom in shingles jabs

https://www.theguardian.com/society/2026/oct/11/dementia-demand-for-shingles-vaccine-is-soaring

#Dementia #Science #Health #Vaccinesandimmunisation #Society #Healthwellbeing #Lifeandstyle #Alzheimers #Medicalresearch #TheGuardian #IanSampleScienceeditor

Plasma PINK1/Parkin ratio and ATF5 as potential biomarkers associated with dyskinesia in Parkinson's disease.

Neurobiol Dis. 2026 Oct 5;230:107638. Epub 2026 Oct 5Authors: Qian S, Xiang W, Chen K, Du Y, Xu B, Duan Q, Xiong X, Hou J, Jiang T, Xie D, Qian J, Xie C, Li JPubMed: 42833593Submit Comment

Read more: https://www.alzforum.org/papers/plasma-pink1parkin-ratio-and-atf5-potential-biomarkers-associated-dyskinesia-parkinsons
#Dementia #Alzheimers #Autism #Caregiving

The Cost of Safety: Balancing Biosafety and Histologic Integrity in Prion Research.

J Exp Neurol. 2026;7(3):120-124. Authors: Seerley A, Panter AGPubMed: 42846668Submit Comment

Read more: https://www.alzforum.org/papers/cost-safety-balancing-biosafety-and-histologic-integrity-prion-research
#Dementia #Alzheimers #Autism #Caregiving

Culture-Agnostic and Culture-Specific Analyses of Semantic Fluency in Korean and English Speakers With Alzheimer's Disease.

Am J Speech Lang Pathol. 2026 Oct 2;:1-14. Epub 2026 Oct 2Authors: Shin J, García AM, Scimeca M, Kiran S, Sung JEPubMed: 42825683Submit Comment

Read more: https://www.alzforum.org/papers/culture-agnostic-and-culture-specific-analyses-semantic-fluency-korean-and-english-speakers
#Dementia #Alzheimers #Autism #Caregiving

Oral microbiome-metabolome axis links glycerophospholipid dysregulation to Alzheimer's disease.

J Oral Microbiol. 2026;18(1):2732297. Epub 2026 Sep 29Authors: Jia M, Yang R, Xu Y, Wu Z, Lu J, Li Z, Yan Q, Fan G, Gui YPubMed: 42825245Submit Comment

Read more: https://www.alzforum.org/papers/oral-microbiome-metabolome-axis-links-glycerophospholipid-dysregulation-alzheimers-disease
#Dementia #Alzheimers #Autism #Caregiving

Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.

Alzheimers Dement. 2026 Oct;22(10):e71758. Authors: Pang M, Brothers HM, O'Gorman J, Murphy J, Zabar Y, Lasky T, Shen C, Rubino I, Knopman DPubMed: 42841310Submit Comment

Read more: https://www.alzforum.org/papers/longitudinal-clinical-outcomes-after-amyloid-clearance-aducanumab-phase-3-studies
#Dementia #Alzheimers #Autism #Caregiving

Baseline CSF and plasma glucocerebrosidase activity predict longitudinal cognitive decline in Parkinson's disease: A PPMI longitudinal cohort study.

J Clin Neurosci. 2026 Oct 7;154:112325. Epub 2026 Oct 7Authors: Kazemi EPubMed: 42843141Submit Comment

Read more: https://www.alzforum.org/papers/baseline-csf-and-plasma-glucocerebrosidase-activity-predict-longitudinal-cognitive-decline
#Dementia #Alzheimers #Autism #Caregiving

Relationship Between Braak and Clinical Stage in Autopsy-Confirmed Parkinson Disease: A UK Brain Bank Study.

Neurology. 2026 Nov 10;107(9):e218469. Epub 2026 Oct 8Authors: di Biase L, Pecoraro PM, Bugamelli F, Di Carluccio M, Marsili L, Espay AJPubMed: 42848968Submit Comment

Read more: https://www.alzforum.org/papers/relationship-between-braak-and-clinical-stage-autopsy-confirmed-parkinson-disease-uk-brain
#Dementia #Alzheimers #Autism #Caregiving

RE: https://toad.social/@tend2wobble/117417352232167391

Former executive director of The People’s Music Network for Songs of Freedom and Struggle, Ben Grosscup, speaking about his quest to obtain NeuralCIM — a Cuban drug for treating Alzheimer's.

#Alzheimers #BenGrosscup #Cuba #NeuralCIM #treatment #medicine #PMN

Biological amyloids: A scaffold with chemical reactivity.

Curr Opin Struct Biol. 2026 Oct 8;101:103410. Epub 2026 Oct 8Authors: Buratti FA, Wittung-Stafshede PPubMed: 42849105Submit Comment

Read more: https://www.alzforum.org/papers/biological-amyloids-scaffold-chemical-reactivity
#Dementia #Alzheimers #Autism #Caregiving

TDP-43 and ALS - what's wrong with my membranes?

Neurobiol Dis. 2026 Oct 5;:107630. Epub 2026 Oct 5Authors: Dahlhaus R, Yalcin I, Tischer J, Braun RJPubMed: 42833594Submit Comment

Read more: https://www.alzforum.org/papers/tdp-43-and-als-whats-wrong-my-membranes
#Dementia #Alzheimers #Autism #Caregiving

From patient cells to patient therapy: Twenty years of iPSC-based translation in neurodegenerative disease.

Cell Rep Med. 2026 Oct 2;:103104. Epub 2026 Oct 2Authors: Cha Y, Kim KSPubMed: 42826718Submit Comment

Read more: https://www.alzforum.org/papers/patient-cells-patient-therapy-twenty-years-ipsc-based-translation-neurodegenerative-disease
#Dementia #Alzheimers #Autism #Caregiving

Why are some neurons spared in neurodegeneration? Cellular subtype identity maintenance as a candidate threshold-setting mechanism.

PLoS Biol. 2026 Oct;24(10):e3004014. Epub 2026 Oct 5Authors: Kim DWPubMed: 42832419Submit Comment

Read more: https://www.alzforum.org/papers/why-are-some-neurons-spared-neurodegeneration-cellular-subtype-identity-maintenance-candidate
#Dementia #Alzheimers #Autism #Caregiving

From seeds to symptoms: the molecular landscape of tau seeding in Alzheimer's disease.

Front Neurosci. 2026;20:1927017. Epub 2026 Sep 17Authors: Miao J, Xue C, Yan X, Gu J, Chu D, Sun HPubMed: 42824632Submit Comment

Read more: https://www.alzforum.org/papers/seeds-symptoms-molecular-landscape-tau-seeding-alzheimers-disease
#Dementia #Alzheimers #Autism #Caregiving

New Alzheimer's disease diagnostics and psychological clinical perspectives.

Front Psychol. 2026;17:1866853. Epub 2026 Sep 17Authors: Aversi MT, Freitas PM, Aversi-Ferreira TAPubMed: 42824359Submit Comment

Read more: https://www.alzforum.org/papers/new-alzheimers-disease-diagnostics-and-psychological-clinical-perspectives
#Dementia #Alzheimers #Autism #Caregiving

Quantitative handwriting measures discriminate between older adults with and without MMSE-defined cognitive impairment.

Arch Gerontol Geriatr. 2026 Sep 30;152:106436. Epub 2026 Sep 30Authors: Devoli G, Alì PA, Schiavetti I, Balestrino MPubMed: 42837746Submit Comment

Read more: https://www.alzforum.org/papers/quantitative-handwriting-measures-discriminate-between-older-adults-and-without-mmse-defined
#Dementia #Alzheimers #Autism #Caregiving

Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑associated Cognitive Impairment: Mechanistic Synthesis and Meta‑analysis of Clinical Randomized Controlled Trials.

Neurochem Res. 2026 Oct 5;51(5)Authors: Ma T, Zhou H, Liu Y, Cheng X, Li MPubMed: 42831987Submit Comment

Read more: https://www.alzforum.org/papers/electroacupuncture-targeting-nlrp3-inflammasome-senescence-associated-cognitive-impairment
#Dementia #Alzheimers #Autism #Caregiving

Disrupted synaptic vacuolar H+-ATPase renders synaptic vulnerability to Alzheimer's disease.

JCI Insight. 2026 Oct 8;11(19) Epub 2026 Oct 8Authors: Chen Y, Emam KA, Yue S, Tian J, Wang T, Park A, Mishra S, Deep G, Wang ZJ, Du H, Guo LPubMed: 42847994Submit Comment

Read more: https://www.alzforum.org/papers/disrupted-synaptic-vacuolar-h-atpase-renders-synaptic-vulnerability-alzheimers-disease
#Dementia #Alzheimers #Autism #Caregiving

Mitochondrial DNA damage elicits PINK1 upregulation in pontine cholinergic neurons in Parkinson's disease.

Brain. 2026 Oct 7; Epub 2026 Oct 7Authors: Lu H, Pyle A, Steyn JS, Lawless C, Hussain R, Falkenberg M, Elson JL, Pienaar ISPubMed: 42839534Submit Comment

Read more: https://www.alzforum.org/papers/mitochondrial-dna-damage-elicits-pink1-upregulation-pontine-cholinergic-neurons-parkinsons
#Dementia #Alzheimers #Autism #Caregiving

Genetic findings in a Turkish clinical cohort with hereditary Parkinson's disease.

Neurogenetics. 2026 Oct 6;27(1)Authors: Ozata Aksoy D, Tunca Y, Sonkaya AR, Torun D, Korucu OPubMed: 42836888Submit Comment

Read more: https://www.alzforum.org/papers/genetic-findings-turkish-clinical-cohort-hereditary-parkinsons-disease
#Dementia #Alzheimers #Autism #Caregiving

Depression and anxiety in vascular dementia: an update.

J Neural Transm (Vienna). 2026 Oct 7; Epub 2026 Oct 7Authors: Jellinger KAPubMed: 42841964Submit Comment

Read more: https://www.alzforum.org/papers/depression-and-anxiety-vascular-dementia-update
#Dementia #Alzheimers #Autism #Caregiving

A computational-first proof-of-concept for dual-function metal chelation and aggregate neutralization in an Aβ42 Drosophila model.

Front Aging Neurosci. 2026;18:1912315. Epub 2026 Sep 22Authors: Tsai E, Wang Z, Truglio JPubMed: 42840164Submit Comment

Read more: https://www.alzforum.org/papers/computational-first-proof-concept-dual-function-metal-chelation-and-aggregate-neutralization
#Dementia #Alzheimers #Autism #Caregiving

Vaccine data suggest immunity could mitigate dementia. What's the biology behind these apparent effects?

Proc Natl Acad Sci U S A. 2026 Oct 13;123(41):e2633554123. Epub 2026 Oct 7Authors: Madhusoodanan JPubMed: 42842397Submit Comment

Read more: https://www.alzforum.org/papers/vaccine-data-suggest-immunity-could-mitigate-dementia-whats-biology-behind-these-apparent
#Dementia #Alzheimers #Autism #Caregiving

Multimodal neuroimaging in dementia and neurodegenerative disorders: complementary roles of clinically available nuclear medicine and MRI in the era of disease-modifying therapies.

Jpn J Radiol. 2026 Oct 3; Epub 2026 Oct 3Authors: Inui Y, Takechi H, Watanabe H, Kato T, Ito K, Kobayashi R, Toyama H, Inoue MPubMed: 42828695Submit Comment

Read more: https://www.alzforum.org/papers/multimodal-neuroimaging-dementia-and-neurodegenerative-disorders-complementary-roles
#Dementia #Alzheimers

Therapeutic potential of proline-rich peptide-1 (PRP-1) in counteracting amyloid-β-mediated cortical and hippocampal neurodegeneration in a rat model.

Neuroscience. 2026 Oct 3; Epub 2026 Oct 3Authors: Stepanyan H, Ghorbani H, Poghosyan M, Danielyan M, Minasyan A, Hunanyan A, Hunanyan NPubMed: 42829100Submit Comment

Read more: https://www.alzforum.org/papers/therapeutic-potential-proline-rich-peptide-1-prp-1-counteracting-amyloid-v-mediated-cortical
#Dementia #Alzheimers #Autism

STZ‑induced sporadic Alzheimer's in rats: behavioral, histopathological, and MiRNA profiles.

J Mol Histol. 2026 Oct 5;57(5)Authors: Moustafa N, Gaballa Z, Haiba S, Abdellatif APubMed: 42832125Submit Comment

Read more: https://www.alzforum.org/papers/stz-induced-sporadic-alzheimers-rats-behavioral-histopathological-and-mirna-profiles
#Dementia #Alzheimers #Autism #Caregiving

The Popular Joint Supplement Glucosamine May Accelerate Alzheimer’s Progression. Its use is associated with a 25% higher likelihood of mild cognitive impairment progressing to dementia. #Alzheimers #Glucosamine #BrainHealth #DementiaResearch #MedicalNews
https://www.instagram.com/p/DeSDDN5OzNM/