#immunology — Public Fediverse posts

Rituximab (RTX), an intravenous drug primarily known for depleting B cells, has been found to also trigger positive metabolic changes in T cells, specifically improving energy production and lowering cellular stress in patients with nephrotic syndrome who respond favorably to the treatment.
#Immunology #Nephrology #CellularBiology #sflorg
https://www.sflorg.com/2026/09/imgy09092601.html

It is a remarkably humbling realization that a single, unnoticed bite from an arthropod the size of an apple seed can completely rewrite an individual's relationship with the global food chain. Alpha-gal syndrome reminds us that the human immune system, for all its staggering sophistication and atomic-level precision, remains intimately and sometimes precariously tethered to the natural world.
#WhatIs #Immunology #MolecularBiology #EvolutionaryBiology #Entomology #sflorg
https://www.sflorg.com/2026/09/wi09102601.html

Specialized white blood cells known as monocytes move from the bloodstream into the uterus during the menstrual cycle to regulate inflammation, tissue repair, and the maintenance of the womb lining.
#Immunology #ReproductiveBiology #sflorg
https://www.sflorg.com/2026/09/imgy09082601.html

How your body builds billions of custom antibodies in hours. Mind = blown. 🧬✨ #science #biology #cosmos #physics #klytron

#science #biology #cosmos #physics #immunology #klytron

CALL FOR DELEGATES | VACCINES-2027

Connect with experts, exchange ideas & explore emerging perspectives in vaccine research, development and immunology.

📍 Milan, Italy
📅 April 19–20, 2027
📩 [email protected]

🔗 Register Now: https://vaccinesresearch2027.pagesconferences.org/register

Bring your expertise. Join the conversation.

#VACCINES2027 #VaccineResearch #Immunology #Vaccinology #globalHealth

CALL FOR DELEGATES | VACCINES-2027

Connect with experts, exchange ideas & explore emerging perspectives in vaccine research, development and immunology.

📍 Milan, Italy
📅 April 19–20, 2027
📩 [email protected]

🔗 Register Now: https://vaccinesresearch2027.pagesconferences.org/register

Bring your expertise. Join the conversation.

#VACCINES2027 #VaccineResearch #Immunology #Vaccinology #globalHealth

CALL FOR DELEGATES | VACCINES-2027

Connect with experts, exchange ideas & explore emerging perspectives in vaccine research, development and immunology.

📍 Milan, Italy
📅 April 19–20, 2027
📩 [email protected]

🔗 Register Now: https://vaccinesresearch2027.pagesconferences.org/register

Bring your expertise. Join the conversation.

#VACCINES2027 #VaccineResearch #Immunology #Vaccinology #globalHealth

CALL FOR DELEGATES | VACCINES-2027

Connect with experts, exchange ideas & explore emerging perspectives in vaccine research, development and immunology.

📍 Milan, Italy
📅 April 19–20, 2027
📩 [email protected]

🔗 Register Now: https://vaccinesresearch2027.pagesconferences.org/register

Bring your expertise. Join the conversation.

#VACCINES2027 #VaccineResearch #Immunology #Vaccinology #globalHealth

A novel, targeted therapy for multiple sclerosis utilizes the body's own red blood cells to train the immune system to tolerate endogenous structures, preventing it from attacking the central nervous system.
#Immunology #Neurology #ClinicalPathology #Biotechnology #sflorg
https://www.sflorg.com/2026/09/imgy09012601.html

A novel cryopreservation technique utilizing nontoxic antifreeze sugars, such as trehalose and sucrose, to protect CAR-T cells during freezing and thawing without requiring extensive chemical removal prior to patient infusion.
#Bioengineering #Oncology #CellularBiology #Immunology #sflorg
https://www.sflorg.com/2026/08/beng08192601.html

🌱 Plant-Based Vaccine Innovation

How can plant-based technologies transform vaccine manufacturing?

Explore plant-derived platforms, scalable production, and sustainable bioprocessing at #VACCINES2027.

📍 Milan, Italy
📅 April 19–20, 2027
🔗 Learn more: https://vaccinesresearch2027.pagesconferences.org/

📩 Contact: [email protected]

#Vaccines #PlantBasedVaccines #VaccineResearch #Biotechnology #Immunology

TRIM21 induces selective #autophagy of viruses & bacteria.

TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

#innateimmunity #immunity #microbiology #immunology

https://davidojcius.blogspot.com/2026/06/trim21-induces-selective-autophagy-of.html

🐍💉 Tim Friede spent nearly 20 years gradually immunizing himself against #venom from over a dozen deadly #snakes, including #cobras and black #mambas.

Scientists used #antibodies from his blood to create an experimental #antivenom that protected #mice from 13 types of snake venom. The work could lead to a single broad-spectrum antivenom.

👉 https://www.sciencenews.org/article/antivenom-snakebite-tim-friede#msdynmkt_trackingcontext=8c2b5212-1894-4d71-8f8a-03d5c1aa0300

#science #immunology #biology #wildlife #medicine #research #nature #wisconsin #newyork #biotech

🐍💉 Tim Friede spent nearly 20 years gradually immunizing himself against #venom from over a dozen deadly #snakes, including #cobras and black #mambas.

Scientists used #antibodies from his blood to create an experimental #antivenom that protected #mice from 13 types of snake venom. The work could lead to a single broad-spectrum antivenom.

👉 https://www.sciencenews.org/article/antivenom-snakebite-tim-friede#msdynmkt_trackingcontext=8c2b5212-1894-4d71-8f8a-03d5c1aa0300

#science #immunology #biology #wildlife #medicine #research #nature #wisconsin #newyork #biotech

🐍💉 Tim Friede spent nearly 20 years gradually immunizing himself against #venom from over a dozen deadly #snakes, including #cobras and black #mambas.

Scientists used #antibodies from his blood to create an experimental #antivenom that protected #mice from 13 types of snake venom. The work could lead to a single broad-spectrum antivenom.

👉 https://www.sciencenews.org/article/antivenom-snakebite-tim-friede#msdynmkt_trackingcontext=8c2b5212-1894-4d71-8f8a-03d5c1aa0300

#science #immunology #biology #wildlife #medicine #research #nature #wisconsin #newyork #biotech

🐍💉 Tim Friede spent nearly 20 years gradually immunizing himself against #venom from over a dozen deadly #snakes, including #cobras and black #mambas.

Scientists used #antibodies from his blood to create an experimental #antivenom that protected #mice from 13 types of snake venom. The work could lead to a single broad-spectrum antivenom.

👉 https://www.sciencenews.org/article/antivenom-snakebite-tim-friede#msdynmkt_trackingcontext=8c2b5212-1894-4d71-8f8a-03d5c1aa0300

#science #immunology #biology #wildlife #medicine #research #nature #wisconsin #newyork #biotech

🐍💉 Tim Friede spent nearly 20 years gradually immunizing himself against #venom from over a dozen deadly #snakes, including #cobras and black #mambas.

Scientists used #antibodies from his blood to create an experimental #antivenom that protected #mice from 13 types of snake venom. The work could lead to a single broad-spectrum antivenom.

👉 https://www.sciencenews.org/article/antivenom-snakebite-tim-friede#msdynmkt_trackingcontext=8c2b5212-1894-4d71-8f8a-03d5c1aa0300

#science #immunology #biology #wildlife #medicine #research #nature #wisconsin #newyork #biotech

The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
#Immunology #Oncology #Urology #sflorg
https://www.sflorg.com/2026/04/imgy04072601.html

“Inflammasome Activation by the Fungal Pathogen, #Aspergillus fumigatus”

#inflammation #mycology #microbiology #immunity #immunology #innateimmunity

https://hsri.ucmerced.edu/events/valley-fever-seminar-series-david-ojcius-phd

🔬 A new molecular switch for innate immunity: Researchers at the University of Cologne have uncovered a previously unknown signaling component – ANKIB1 and its role in forming K11-ubiquitin chains – crucial for triggering interferons, key antiviral messengers.

Read more ▶️ https://uni.koeln/VQ2FL

📰 https://www.nature.com/articles/s41556-026-01886-z

#uniköln #unicologne #Research #Immunology #Medicine #Science #NatureCellBiology

🔬 A new molecular switch for innate immunity: Researchers at the University of Cologne have uncovered a previously unknown signaling component – ANKIB1 and its role in forming K11-ubiquitin chains – crucial for triggering interferons, key antiviral messengers.

Read more ▶️ https://uni.koeln/VQ2FL

📰 https://www.nature.com/articles/s41556-026-01886-z

#uniköln #unicologne #Research #Immunology #Medicine #Science #NatureCellBiology

🔬 A new molecular switch for innate immunity: Researchers at the University of Cologne have uncovered a previously unknown signaling component – ANKIB1 and its role in forming K11-ubiquitin chains – crucial for triggering interferons, key antiviral messengers.

Read more ▶️ https://uni.koeln/VQ2FL

📰 https://www.nature.com/articles/s41556-026-01886-z

#uniköln #unicologne #Research #Immunology #Medicine #Science #NatureCellBiology

🔬 A new molecular switch for innate immunity: Researchers at the University of Cologne have uncovered a previously unknown signaling component – ANKIB1 and its role in forming K11-ubiquitin chains – crucial for triggering interferons, key antiviral messengers.

Read more ▶️ https://uni.koeln/VQ2FL

📰 https://www.nature.com/articles/s41556-026-01886-z

#uniköln #unicologne #Research #Immunology #Medicine #Science #NatureCellBiology

🔬 A new molecular switch for innate immunity: Researchers at the University of Cologne have uncovered a previously unknown signaling component – ANKIB1 and its role in forming K11-ubiquitin chains – crucial for triggering interferons, key antiviral messengers.

Read more ▶️ https://uni.koeln/VQ2FL

📰 https://www.nature.com/articles/s41556-026-01886-z

#uniköln #unicologne #Research #Immunology #Medicine #Science #NatureCellBiology

🧪 ELISA techniques enable accurate antigen detection 🔬, supporting diagnostics, research, and clinical testing through sensitive immunoassays 📊.
#ELISA #Immunoassay #ClinicalDiagnostics #Biotechnology #Immunology #LifeScienceStudents #LaboratoryTechniques #MedicalTesting #ResearchLabs #BioResire

Symptom: Mast Cell Itching

https://www.illmarks.com/symptom-mast-cell-itching/

#allergicreactions #Allergies #allergy #art #bodyHorror #bodyMapping #buildingSafety #chonicillness #chronicIllness #claws #eds #ehlersdanlossyndrome #environmentalIllness #environmentalillness #fingers #formaldehyde #heds #hypermobile #hypermobility #hypermobilityspectrumdisorder #immunology #itched #itching #longCovid #longcovid #mastCell #mastCellActivationSyndrome #mastcell #mastcellactivationsyndrome #mastcelldisease #mastocytosis #mcas #medicalArt #MillionsMissing #nails #POTS #prop65 #publicHealth #publicHealth #pwLC #pwme #scratched #scratching #scratchy #severeallergy #vocs

2025 September & October: So tired of this same MCAS nightmare

https://www.illmarks.com/2025-september-october-so-tired-of-this-same-mcas-nightmare/

#Allergies #art #bodyHorror #bodyMapping #bodyhorror #bodymapping #buildingbiology #chemicallysensitive #chronicIllness #chronicIllness #GI #immunology #longCovid #longcovid #mastCell #mastcell #mastcellactivationsyndrome #medicalArt #MillionsMissing #pwLC #pwme

2025-8-9 I almost went in to anaphylaxis from drinking water.

https://www.illmarks.com/2025-8-9-i-almost-went-in-to-anaphylaxis-from-drinking-water/

#allergy #art #autoimmune #bodyHorror #bodyMapping #chronicIllness #immune #immunology #longCovid #longcovid #mastCell #mastcell #mcas #medArt #medBlog #medart #medicalArt #MillionsMissing #pwLC #pwme #sciArt #sciBlog #SciArt

The #neurological #damage caused by #EV71 #infection is associated with hsa_circ_0069335/miR-29b/PMP22 pathway

Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.00844-24?af=R

ABSTRACT
Enterovirus 71 (EV71) infection is usually accompanied by neurological damage, which is the leading cause of death in children with hand-foot-mouth disease. In this study, we demonstrated that EV71 infection can cause pathological damage in the nervous system, such as neuronal vacuolar degeneration, shrinkage of some neurons, edema of brain tissues in the hippocampus, and a decreased number of Nissl bodies in the infarction area. Also, EV71 infection caused apparent structural damage to Schwann cells, including a decreased number of cytoplasmic organelles and severe damage of rough endoplasmic reticulum and mitochondria. However, the pathological damage was alleviated with the decrease of EV71 viral load. The cell experiment in vitro showed that EV71 infection significantly reduced ATP levels and promoted Schwann cell apoptosis, thus inhibiting cell growth. The extended infection time and the decreased viral load resulted in the gradual improvement of cell growth status. Meanwhile, EV71 inhibited the expression of miR-29b and promoted the expression of PMP22 in a time-dependent manner at both mRNA and protein levels, with the most significant change at 36 h of infection. Subsequently, the expression of miR-29b and PMP22 was gradually restored with the reduction of EV71 viral load. In addition, EV71 regulated the expression of hsa_circ_0069335, which could bind and co-localize with miR-29b. Therefore, EV71 infection can cause significant damage to the nervous system and may be related to hsa_circ_0069335/miR-29b/PMP22 pathway. The present study provides a new therapeutic target for neurological damage induced by EV71 infection.

____

#abstract #COVID19 #encephalitis #enterovirus #ENTEROVIRUS71 #ev71 #health #HFMD #immunology #neuroinvasion #nutrition #research #wellness

... specific functional expression programs correlated with fluctuations in various #Tcell subsets, which may be associated with #AML progression and relapse. Furthermore, our analysis of cellular communication networks led to the identification of #VISTA, #CD244, and #TIM3 as potential #immunotherapeutic targets in pediatric AML."

https://pubmed.ncbi.nlm.nih.gov/38844062/

Nice work by Yuan et al., using #scRNAseq and #scTCRseq. No huge discoveries, but of interest nonetheless.

#science #cancer #immunology

Plenary Speaker Profile: Meet Dr. Meriem Messaoudene, Scientific Director of the Centre hospitalier de l'Université de Montréal (CHUM) microbiome centre, who will speak about microbiota-centered interventions in onco-immunology at #HavingIMPACTT2024

#speaker #conference #symposium #research #microbiota #microbiome #cancer #cancertherapy #immunology

Mark your calendars: registration & abstract submissions open on Dec 1, 2023 for our #HavingIMPACTT2024 symposium! Head to our website for details, and don't forget to sign up for updates so you don't miss out: https://www.impactt-microbiome.ca/having-impactt-2024-symposium/

#microbiome #microbiota #symposium #conference #research #datascience #health #bioinformatics #biology #multiomics #metabolomics #proteomics #transcriptomics #cancer #gutbrainaxis #immunology #science #

Nice papers that #neutrophils can also be epigenetically reprogrammed by infection - stemming from effects on stem cells.

Both use #zebrafish as model

#Shigella: https://www.science.org/doi/full/10.1126/sciadv.adf9706

#Salmonella: https://www.science.org/doi/10.1126/sciadv.adf9904
#trainedimmunity #immunology #epigenetics

05/2023 Issue ➡️ https://bit.ly/3VPM25i
text mining to assemble molecular mechanisms, modular organisation of human #proteome, transcriptional regulation of #metabolism...
Cover (DrawImpacts): IFN-β activation of inflammatory genes from Alex Hoffmann's lab, UCLA
#immunology #signalling #systemsbiology

In Aicardi-Goutières syndrome patient samples

"Using machine-learning approaches and differential gene expression we identified a drastic loss of transcription factor hypoxia induced factor 1 alpha (HIF-1a) expression and activity associated with features of a metabolic switch and mitochondrial stress in monocytes/dendritic cells."

#Preprint #Immunology #geneticdisease

https://www.biorxiv.org/content/10.1101/2023.02.23.529707v1

"Our findings underscore the importance of cell death in defense against intracellular bacterial pathogens and provide an example of how layered and hierarchical immune pathways can provide robust defense against pathogens that have evolved a broad arsenal of virulence factors."

#Shigella #HostPathogen #CellDeath #Apoptosis #InnateImmunity #Pathogen #Microbiology #Immunology

https://elifesciences.org/articles/83639

New review from the Peters Lab at LJI: "T-cell epitope discovery and single-cell technologies to advance food allergy research"

As they write, "Advancements in single-cell T-cell receptor (TCR) sequencing in combination with transcriptome analysis provide exciting opportunities for identification and characterization of the TCR repertoires of allergen-specific T cells."

https://doi.org/10.1016/j.jaci.2022.10.025

#Tcells #FoodAllergy #Epitopes #Immunology #ImmuneSystem #CellularBiology #Genomics #OpenAccess

How does HIV alter host cells?

If you're interested in #virology, check out this recent LJI External Seminar: https://www.youtube.com/watch?v=cbAJ2ZB-x8E

"Discovering mechanisms of host cellular remodeling by viral pathogens with quantitative proteomics" from Jeffery Johnson, PhD. Associate Professor, Icahn School of Medicine at Mount Sinai, Department of Microbiology.

#Proteomics #Immunology #Viruses #CellularBiology #MolecularBiology #InfectiousDisease #Microbiology #HIV #CRISPR #SARSCoV2

New #colitis study from LJI's Kronenberg Lab: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034648/full

The team investigated whether increased expression of two GPRs (GPR183 and GPR18) in the intestine is related to disease severity in colitis models.

#Immunology #Tcells #ImmuneSystem #CellularBiology #MolecularBiology #GPRs #infammation #BowelDisease #Health #MouseModels

A #thread of recent papers coauthored by Eörs Szathmáry on learning and evolution, covering Darwinian principles in the immune system, brain, Bayesian learning theory.

Mentioned in today's #KLIAustria #KLIColloquium talk.

#evolution #ecoevo #EvolutionaryBiology #EvolutionaryAlgorithm #Darwin #Darwinian #Learning #LearningTheory #Bayesian #neuroscience #immunology #PaperThread #