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#immunology — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #immunology, aggregated by home.social.

  1. Rituximab (RTX), an intravenous drug primarily known for depleting B cells, has been found to also trigger positive metabolic changes in T cells, specifically improving energy production and lowering cellular stress in patients with nephrotic syndrome who respond favorably to the treatment.
    #Immunology #Nephrology #CellularBiology #sflorg
    sflorg.com/2026/09/imgy0909260

  2. It is a remarkably humbling realization that a single, unnoticed bite from an arthropod the size of an apple seed can completely rewrite an individual's relationship with the global food chain. Alpha-gal syndrome reminds us that the human immune system, for all its staggering sophistication and atomic-level precision, remains intimately and sometimes precariously tethered to the natural world.
    #WhatIs #Immunology #MolecularBiology #EvolutionaryBiology #Entomology #sflorg
    sflorg.com/2026/09/wi09102601.

  3. First, a paper suggesting that random-sequence mRNA vaccines enhance anti-tumor effects, and now another claiming that random, nonspecific T cells are sufficient to eliminate tumors. So much for antigen specificity.

    #science
    #immunology

    nature.com/articles/s41590-026

  4. Specialized white blood cells known as monocytes move from the bloodstream into the uterus during the menstrual cycle to regulate inflammation, tissue repair, and the maintenance of the womb lining.
    #Immunology #ReproductiveBiology #sflorg
    sflorg.com/2026/09/imgy0908260

  5. 🌐 vaccinesresearch2027.pagesconferences.org

    ONE FIELD. MANY PERSPECTIVES. ONE GOAL.

    Vaccine science moves forward when research, immunology, development, and global expertise come together.

    Join VACCINES-2027 in Milan for meaningful scientific exchange, emerging ideas, and new perspectives shaping the future of vaccine research.

    📍 Milan, Italy
    📅 April 19–20, 2027
    📩 [email protected]

    #VACCINES2027 #VaccineResearch #Immunology #Vaccinology #ScientificResearch #GlobalHealth

  6. 🌐 vaccinesresearch2027.pagesconferences.org

    ONE FIELD. MANY PERSPECTIVES. ONE GOAL.

    Vaccine science moves forward when research, immunology, development, and global expertise come together.

    Join VACCINES-2027 in Milan for meaningful scientific exchange, emerging ideas, and new perspectives shaping the future of vaccine research.

    📍 Milan, Italy
    📅 April 19–20, 2027
    📩 [email protected]

    #VACCINES2027 #VaccineResearch #Immunology #Vaccinology #ScientificResearch #GlobalHealth

  7. 🌐 vaccinesresearch2027.pagesconferences.org

    ONE FIELD. MANY PERSPECTIVES. ONE GOAL.

    Vaccine science moves forward when research, immunology, development, and global expertise come together.

    Join VACCINES-2027 in Milan for meaningful scientific exchange, emerging ideas, and new perspectives shaping the future of vaccine research.

    📍 Milan, Italy
    📅 April 19–20, 2027
    📩 [email protected]

    #VACCINES2027 #VaccineResearch #Immunology #Vaccinology #ScientificResearch #GlobalHealth

  8. 🌐 vaccinesresearch2027.pagesconferences.org

    ONE FIELD. MANY PERSPECTIVES. ONE GOAL.

    Vaccine science moves forward when research, immunology, development, and global expertise come together.

    Join VACCINES-2027 in Milan for meaningful scientific exchange, emerging ideas, and new perspectives shaping the future of vaccine research.

    📍 Milan, Italy
    📅 April 19–20, 2027
    📩 [email protected]

    #VACCINES2027 #VaccineResearch #Immunology #Vaccinology #ScientificResearch #GlobalHealth

  9. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  10. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  11. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  12. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  13. TRIM21 induces selective #autophagy of viruses & bacteria.

    TRIM21 drives antibody‑directed #xenophagy , rapidly ubiquitinating pathogens & routing diverse viral & bacterial cargo to lysosomes.

    #innateimmunity #immunity #microbiology #immunology

    davidojcius.blogspot.com/2026/

  14. my father died ravaged by #dementia, so this is a topic near and dear to me for more than 20 years now.

    what is interesting to me about this study is that it validates the #immunology hypothesis about #Alzheimer's #dementia. some studies see it as a consequence of general inflammation, aka autoimmune reaction to unknown triggers. others pointed to #diabetes, suggesting it’s a Type 3.

    and the knowledge of #herpes as a dementia trigger is much older.

    🧵…

  15. The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
    #Immunology #Oncology #Urology #sflorg
    sflorg.com/2026/04/imgy0407260

  16. The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
    #Immunology #Oncology #Urology #sflorg
    sflorg.com/2026/04/imgy0407260

  17. The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
    #Immunology #Oncology #Urology #sflorg
    sflorg.com/2026/04/imgy0407260

  18. The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
    #Immunology #Oncology #Urology #sflorg
    sflorg.com/2026/04/imgy0407260

  19. The discovery that specific immune cells, known as tissue-resident memory T cells, migrate to and establish long-term residency within the #prostate to guard against infections and potentially combat disease.
    #Immunology #Oncology #Urology #sflorg
    sflorg.com/2026/04/imgy0407260

  20. Systemic candidiasis is a severe, opportunistic #fungal infection caused by Candida albicans. Recent research demonstrates that reprogramming the metabolic pathways of a host's immune cells offers a viable strategy to clear the infection, circumventing the need for traditional #antifungal medications.
    #Immunology #Microbiology #sflorg
    sflorg.com/2026/04/imgy0403260

  21. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  22. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  23. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  24. 'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.'
    #Immunology #InnateImmunity
    sciencedirect.com/science/arti

  25. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  26. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  27. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  28. 'Thus, here we asked whether B. bassiana could damage the Drosophila brain via Toll-1, Wek and Sarm. We show that exposure to B. bassiana reduced fly lifespan and impaired locomotion. B. bassiana entered the brain and induced the up-regulation of AMPs, as well as wek and sarm, within the brain. Exposure to B. bassiana caused neuronal and glial loss in the adult Drosophilabrain. Importantly, RNAi knockdown of Toll-1, wek or sarm concomitantly with infection prevented B. bassiana induced cell loss.'
    #Immunology #InnateImmunity
    #Preprint
    biorxiv.org/content/10.1101/20

  29. 'Stimulator of IFN genes (STING) is a critical component of the innate immune system, playing an essential role in defending against DNA virus infections. However, the mechanisms governing basal STING regulation remain poorly understood. In this study, we demonstrate that the basal level of STING is critically maintained by hypoxia-inducible factor 1 (HIF-1)α through transcription.'
    #Immunology #InnateImmunity
    journals.aai.org/jimmunol/arti

  30. 'Stimulator of IFN genes (STING) is a critical component of the innate immune system, playing an essential role in defending against DNA virus infections. However, the mechanisms governing basal STING regulation remain poorly understood. In this study, we demonstrate that the basal level of STING is critically maintained by hypoxia-inducible factor 1 (HIF-1)α through transcription.'
    #Immunology #InnateImmunity
    journals.aai.org/jimmunol/arti

  31. 'Stimulator of IFN genes (STING) is a critical component of the innate immune system, playing an essential role in defending against DNA virus infections. However, the mechanisms governing basal STING regulation remain poorly understood. In this study, we demonstrate that the basal level of STING is critically maintained by hypoxia-inducible factor 1 (HIF-1)α through transcription.'
    #Immunology #InnateImmunity
    journals.aai.org/jimmunol/arti

  32. 'Stimulator of IFN genes (STING) is a critical component of the innate immune system, playing an essential role in defending against DNA virus infections. However, the mechanisms governing basal STING regulation remain poorly understood. In this study, we demonstrate that the basal level of STING is critically maintained by hypoxia-inducible factor 1 (HIF-1)α through transcription.'
    #Immunology #InnateImmunity
    journals.aai.org/jimmunol/arti

  33. 'Here we studied the endogenous TLR pathways in human and mouse macrophages. We provide evidence that myddosomes are dynamic and long-lived entities, numbering in the dozens within individual cells. We demonstrate that the complex cellular responses of the entire TLR pathway are coordinated and executed from within these structures.'
    #Immunology #InnateImmunity
    nature.com/articles/s41586-024