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#biomarker — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #biomarker, aggregated by home.social.

  1. #FDA just approved Qalsody (tofersen) for #ALS with #SOD1 mutation (~2% of ALS cases), based on a ⬇️ of the #biomarker neurofilament (NFL) in the plasma.
    🔹 ALS is a progressive neurodegenerative disorder, attacking nerve cells that control voluntary muscles (e.g., breathing)
    🔹 Qalsody is given intrathecally (in the spine) with 3 initial doses at 14-day intervals and maintenance every 28 days
    🔹 Most common side effects were pain, fatigue, joint pain, ⬆️ white blood cells in the CSF, and muscle pain