home.social

#apoe4 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #apoe4, aggregated by home.social.

fetched live
  1. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY PSYCHOLOGY FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neuroscience #MemoryLoss #EarlyDetection #MouseModel #GeneTherapy #NeuralCircuits

  2. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY PSYCHOLOGY FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neuroscience #MemoryLoss #EarlyDetection #MouseModel #GeneTherapy #NeuralCircuits

  3. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY PSYCHOLOGY FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neuroscience #MemoryLoss #EarlyDetection #MouseModel #GeneTherapy #NeuralCircuits

  4. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neurodegeneration #MemoryLoss #AlzheimersResearch #Neurons #MiceStudy #EarlyIntervention

  5. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neurodegeneration #MemoryLoss #AlzheimersResearch #Neurons #MiceStudy #EarlyIntervention

  6. DATE: August 23, 2026 at 11:15AM
    SOURCE: SCIENCE DAILY MIND-BRAIN FEED

    TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

    URL: sciencedaily.com/releases/2026

    Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

    URL: sciencedaily.com/releases/2026

    -------------------------------------------------

    Private, vetted email list for mental health professionals: clinicians-exchange.org

    Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot

    -------------------------------------------------

    #psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neurodegeneration #MemoryLoss #AlzheimersResearch #Neurons #MiceStudy #EarlyIntervention

  7. Pesquisadores do Gladstone Institutes descobriram um mecanismo cerebral que pode explicar o maior risco de Alzheimer em portadores do gene APOE4. O estudo, publicado na revista Nature Aging, mostra que alterações na atividade neuronal podem ocorrer anos antes de problemas de memória.

    🔗 omniletters.com/mudancas-cereb

    #alzheimer #saudemental #neurociencia #pesquisa #apoe4

  8. MIND OVER MATTER? OR BRAIN FUEL? NEW INSIGHTS ON DEMENTIA'S ADVANCE

    Learn how positive beliefs about aging, certain personality traits, and the MIND diet can lower dementia risk, even for those with genetic predispositions.

    #DementiaRisk, #AgingWell, #MindDiet, #CognitiveHealth, #APOE4

    newsletter.tf/positive-age-bel

  9. europesays.com/ch/34508/ Roche receives CE mark for first IVD immunoassay blood test to identify carriers of ApoE4, a genetic variant present in up to 60% of patients diagnosed with Alzheimer’s disease #Alzheimer #ApoE4 #Blood #carriers #diagnosed #disease #first #genetic #identify #immunoassay #mark #patients #present #receives #Roche #test #variant

  10. europesays.com/uk/517919/ Dr. Juan Fortea discusses his groundbreaking research redefining APOE4 homozygosity as a genetic cause of Alzheimer’s and his upcoming webinar #Alzheimer's #apoe4 #Fortea #Genetics #Research #Science #UK #UnitedKingdom

  11. Dr. Juan Fortea discusses his groundbreaking research redefining APOE4 homozygosity as a genetic cause of Alzheimer’s and his upcoming webinar

    WASHINGTON, Oct. 21, 2025 /PRNewswire/ — APOE4 Alzheimer’s Alliance Board Member Perry S. Chen discusses Dr. Fortea’s groundbreaking…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Alzheimer's #APOE4 #Fortea #Research #Science
    newsbeep.com/us/241771/

  12. Dr. Juan Fortea discusses his groundbreaking research redefining APOE4 homozygosity as a genetic cause of Alzheimer’s and his upcoming webinar

    WASHINGTON, Oct. 21, 2025 /PRNewswire/ — APOE4 Alzheimer’s Alliance Board Member Perry S. Chen discusses Dr. Fortea’s groundbreaking…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Alzheimer's #APOE4 #Fortea #Research #Science
    newsbeep.com/us/241771/

  13. Dr. Juan Fortea discusses his groundbreaking research redefining APOE4 homozygosity as a genetic cause of Alzheimer’s and his upcoming webinar

    WASHINGTON, Oct. 21, 2025 /PRNewswire/ — APOE4 Alzheimer’s Alliance Board Member Perry S. Chen discusses Dr. Fortea’s groundbreaking…
    #NewsBeep #News #Genetics #Alzheimer's #apoe4 #Fortea #research #Science #UK #UnitedKingdom
    newsbeep.com/uk/216164/

  14. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  15. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  16. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  17. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  18. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  19. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  20. A HS student emailed me out of the blue to do an interview as part of her capstone project on #Alzheimer's. I spoke w/her about #brain science & #caregiving. She's 18, her family has the #APOE4 gene - a risk factor for the disease - & she will study neuroscience to find a cure for Alzheimer's. She's smart, determined, & I had chills listening to her story and her passion. The senseless, fascistic #NIH cuts are imperiling the potential, the future of people like her, & our own.

    #EndAlz
    #USPol

  21. Study Suggests #Genetics as a Cause, Not Just a Risk, for Some #Alzheimer’s
    People with two copies of the #gene variant #APOE4 are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such #patients could be diagnosed years before symptoms.
    nytimes.com/2024/05/06/health/
    archive.ph/yTtsM

  22. Study Suggests #Genetics as a Cause, Not Just a Risk, for Some #Alzheimer’s
    People with two copies of the #gene variant #APOE4 are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such #patients could be diagnosed years before symptoms.
    nytimes.com/2024/05/06/health/
    archive.ph/yTtsM

  23. Study Suggests as a Cause, Not Just a Risk, for Some ’s
    People with two copies of the variant are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such could be diagnosed years before symptoms.
    nytimes.com/2024/05/06/health/
    archive.ph/yTtsM

  24. Study Suggests #Genetics as a Cause, Not Just a Risk, for Some #Alzheimer’s
    People with two copies of the #gene variant #APOE4 are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such #patients could be diagnosed years before symptoms.
    nytimes.com/2024/05/06/health/
    archive.ph/yTtsM

  25. A long-awaited AlzForum's take on the news that ApoE4 homozygotism means in fact an AD pathology (though not necessarily dementia before death), alzforum.org/news/research-new

    The comments-section gives a glimpse of some of the trenchlines regarding the treatment of dementia, but I guess the prevention-camp has only just been strirred up from their Sleeping Beauty's slumber.

    I, as an example, still have only a 1 % measured risk of acquiring AD, according to some widely used screens, and no "preventable risk factors" except maybe age. Too bad, my genetic inheritance seems to have been enough to skew the Amyloid-Beta balance early on. Luckily, I was recruited to the aducanumab-study for four years (a precursor of lecanemab with more severe side-effects), and probably got some more years to be able to think things like these.

    #alzheimer #research #medical #APOE4 #alzForum #dementia #ad #alzheimers #amyloid #lecanemab #aducanumab #prevention #cure

  26. A long-awaited AlzForum's take on the news that ApoE4 homozygotism means in fact an AD pathology (though not necessarily dementia before death), alzforum.org/news/research-new

    The comments-section gives a glimpse of some of the trenchlines regarding the treatment of dementia, but I guess the prevention-camp has only just been strirred up from their Sleeping Beauty's slumber.

    I, as an example, still have only a 1 % measured risk of acquiring AD, according to some widely used screens, and no "preventable risk factors" except maybe age. Too bad, my genetic inheritance seems to have been enough to skew the Amyloid-Beta balance early on. Luckily, I was recruited to the aducanumab-study for four years (a precursor of lecanemab with more severe side-effects), and probably got some more years to be able to think things like these.

    #alzheimer #research #medical #APOE4 #alzForum #dementia #ad #alzheimers #amyloid #lecanemab #aducanumab #prevention #cure

  27. A long-awaited AlzForum's take on the news that ApoE4 homozygotism means in fact an AD pathology (though not necessarily dementia before death), alzforum.org/news/research-new

    The comments-section gives a glimpse of some of the trenchlines regarding the treatment of dementia, but I guess the prevention-camp has only just been strirred up from their Sleeping Beauty's slumber.

    I, as an example, still have only a 1 % measured risk of acquiring AD, according to some widely used screens, and no "preventable risk factors" except maybe age. Too bad, my genetic inheritance seems to have been enough to skew the Amyloid-Beta balance early on. Luckily, I was recruited to the aducanumab-study for four years (a precursor of lecanemab with more severe side-effects), and probably got some more years to be able to think things like these.

    #alzheimer #research #medical #APOE4 #alzForum #dementia #ad #alzheimers #amyloid #lecanemab #aducanumab #prevention #cure

  28. #Alzheimer-Forschung und die Entdeckung der Bedeutung des #APOE4 Gens: >>[...]die Ergebnisse würden die Art und Weise ändern, wie Forscher über Alzheimer denken und wie sie die Krankheit erforschen. Sie verankerten APOE4 »als kausalen Faktor von Alzheimer, und nicht nur als Risikofaktor.« Es sei dringend notwendig, ein Medikament zu entwickeln, das speziell darauf abziele.
    Alfredo Ramírez, Leiter der Sektion Molecular Neuropsychiatry an der Uniklinik Köln, überzeugen die Ergebnisse: »Es gibt nicht mehr viel zu tun, um APOE4 als monogene Form der Alzheimer-Krankheit zu betrachten.« Als monogen werden Erkrankungen bezeichnet, die durch eine Mutation in einem einzelnen Gen ausgelöst werden, bekannt sind sie auch als Ein-Gen-Krankheiten. Es müsse aber unter anderem noch korrekt bestimmt werden, wie hoch für Menschen mit zwei APOE4-Genen die Wahrscheinlichkeit tatsächlich sei, an Alzheimer zu erkranken.<<
    https://www.msn.com/de-de/gesundheit/other/alzheimer-menschen-mit-dieser-mutation-bekommen-die-krankheit-fast-immer/ar-BB1lXwle?ocid=Bing