#variant — Public Fediverse posts

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

Redheads are ‘spreading across the globe’ as humans are still evolving | World | News

Britain’s Prince Harry may have done more to boost the profile of redheads than he has for the…
#NewsBeep #News #Health #Evolution #GB #geneticvariants #humanevolution #naturalselection #Redheads #UK #UnitedKingdom #Variant
https://www.newsbeep.com/uk/542048/

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

Skybound, Image & Hasbro Drop Explosive Energon Universe 2026 Variant Covers
Energon Universe FCBD Special 2026 serves as both a perfect jumping...
https://comiccrusaders.com/comic-books/comic-book-previews/skybound-image-hasbro-drop-explosive-energon-universe-2026-variant-covers/
#Skybound #Image Comics #Hasbro #Energon Universe #Energon Universe Special 2026 #M.A.S.K. #Transformers #G.I. Joe #Void Rivals #Robert Kirkman #Joshua Williamson #Dan Watters #Pye Parr #comic book news #variant covers

Skybound, Image & Hasbro Drop Explosive Energon Universe 2026 Variant Covers
Energon Universe FCBD Special 2026 serves as both a perfect jumping...
https://comiccrusaders.com/comic-books/comic-book-previews/skybound-image-hasbro-drop-explosive-energon-universe-2026-variant-covers/
#Skybound #Image Comics #Hasbro #Energon Universe #Energon Universe Special 2026 #M.A.S.K. #Transformers #G.I. Joe #Void Rivals #Robert Kirkman #Joshua Williamson #Dan Watters #Pye Parr #comic book news #variant covers

Skybound, Image & Hasbro Drop Explosive Energon Universe 2026 Variant Covers
Energon Universe FCBD Special 2026 serves as both a perfect jumping...
https://comiccrusaders.com/comic-books/comic-book-previews/skybound-image-hasbro-drop-explosive-energon-universe-2026-variant-covers/
#Skybound #Image Comics #Hasbro #Energon Universe #Energon Universe Special 2026 #M.A.S.K. #Transformers #G.I. Joe #Void Rivals #Robert Kirkman #Joshua Williamson #Dan Watters #Pye Parr #comic book news #variant covers

Skybound, Image & Hasbro Drop Explosive Energon Universe 2026 Variant Covers
Energon Universe FCBD Special 2026 serves as both a perfect jumping...
https://comiccrusaders.com/comic-books/comic-book-previews/skybound-image-hasbro-drop-explosive-energon-universe-2026-variant-covers/
#Skybound #Image Comics #Hasbro #Energon Universe #Energon Universe Special 2026 #M.A.S.K. #Transformers #G.I. Joe #Void Rivals #Robert Kirkman #Joshua Williamson #Dan Watters #Pye Parr #comic book news #variant covers

Skybound Reveals First Look at Super Creepshow #2 and Its Superpowered Vampire Horror
When the Creep-Signal lights up the sky, that ain’t a cry...
https://comiccrusaders.com/comic-books/skybound-super-creepshow-2-first-look-superpowered-vampires/
#Super Creepshow #Super Creepshow #2 #Creepshow #Skybound #Image Comics #Greg Nicotero #Gerry Duggan #Marv Wolfman #Michele Rubini #Scott Buoncristiano #horror comics #anthology comics #vampire comics #superhero horror #comic book news #variant covers

Skybound Reveals First Look at Super Creepshow #2 and Its Superpowered Vampire Horror
When the Creep-Signal lights up the sky, that ain’t a cry...
https://comiccrusaders.com/comic-books/skybound-super-creepshow-2-first-look-superpowered-vampires/
#Super Creepshow #Super Creepshow #2 #Creepshow #Skybound #Image Comics #Greg Nicotero #Gerry Duggan #Marv Wolfman #Michele Rubini #Scott Buoncristiano #horror comics #anthology comics #vampire comics #superhero horror #comic book news #variant covers

Skybound Reveals First Look at Super Creepshow #2 and Its Superpowered Vampire Horror
When the Creep-Signal lights up the sky, that ain’t a cry...
https://comiccrusaders.com/comic-books/skybound-super-creepshow-2-first-look-superpowered-vampires/
#Super Creepshow #Super Creepshow #2 #Creepshow #Skybound #Image Comics #Greg Nicotero #Gerry Duggan #Marv Wolfman #Michele Rubini #Scott Buoncristiano #horror comics #anthology comics #vampire comics #superhero horror #comic book news #variant covers

Early #Detection and #Surveillance of the #SARS-CoV-2 #Variant #BA32 — Worldwide, November 2024–February 2026 (US CDC, MMWR, March 19 '26), https://etidiohnew.blogspot.com/2026/03/early-detection-and-surveillance-of.html

Flu cases tick up in Massachusetts as health officials warn of new variant

Flu cases in Boston and across Massachusetts are continuing to tick up as a new variant circulates, with…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Healthcare #cdc #Doctor #Flu #Health #hospital #illness #Influenza #sick #strain #SubcladeK #variant
https://www.newsbeep.com/us/385696/

#ZMAngband #traditionalroguelike #variant #turnbasedrpg #roguelikedev
Oh man, something nice' s a-cooking. I think I'm getting more and more familiar with the Ancestral Zangband Code, it's like deciphering neolitic cave art, gives me the jeebies but I like it. Btw, installing #VSCode was a bright idea, was NOT expecting it to be so good when used along with #Vim .
Next update is so dear to me that might as well advance a whole number.

#ZMAngband #traditionalroguelike #variant #turnbasedrpg #roguelikedev Latest patch, with some last minute fixes and corrections, has been tested and released. Up on itchio for you folks to download it. Somebody on win11 was reporting of a weird save/autosave bug. 0.8b is available. Get your copy!

#ZMAngband #traditionalroguelike #turnbasedrpg #Variant hello there! 0.7G is up for grabbing! Getting more and more polished gameplay, more variety of Inventory, for more choices to your runs! And more enemies to haunt your sleepless nights!
Every update takes the Variant closer to my goal, which is to provide an honest fun time to all who start a game :)
Working on more Vaults/Special Rooms to add, which is a pending thing I owe my Variant. And obv, I have couple more ideas always in store :)

@lunte161 @c_merriweather @itsfoss
What my head are these?

Anyway, someone might help…
https://todon.eu/@lunte161/115368325687273863

#Linux #Ubuntu #LinuxNewbies #LinuxTools #LinuxTool #LinuxHelp #newbie #newbies #saveMe #PCs #LinuxNewbie #help #LinuxForum #UbuntuHelp #LinuxMint #ZorinOS #WindowsEOL #MSWindows #Windows10EOL #windows10alternative #Windows10 #Windows11 #Windows10vsWindows11 #tracking #dataCollection #AI #ArtificialIntelligence #privacy #privacyMatters #MicroShit #Windoze #windoze11 #software #WindowsAlternative #WindowsAlternatives #migrate2Linux #MigrateToLinux #seekHelp #dev #devs #Development #developer #developers #develop #edit #extract #inject #files #tool #tools #image #images #trd #ZXSpectrum #BetaDisk #start #Interface1 #ZXSpectrums #emulator #emulators #Pentagon #Scorpion #Evolution #Sprinter #Clone #Variant #Variants #MAME #build #Windows #util #utils #vintage #vintageComputing #substitute #substitutes

@lunte161 @c_merriweather @itsfoss
What my head are these?

Anyway, someone might help…
https://todon.eu/@lunte161/115368325687273863

#Linux #Ubuntu #LinuxNewbies #LinuxTools #LinuxTool #LinuxHelp #newbie #newbies #saveMe #PCs #LinuxNewbie #help #LinuxForum #UbuntuHelp #LinuxMint #ZorinOS #WindowsEOL #MSWindows #Windows10EOL #windows10alternative #Windows10 #Windows11 #Windows10vsWindows11 #tracking #dataCollection #AI #ArtificialIntelligence #privacy #privacyMatters #MicroShit #Windoze #windoze11 #software #WindowsAlternative #WindowsAlternatives #migrate2Linux #MigrateToLinux #seekHelp #dev #devs #Development #developer #developers #develop #edit #extract #inject #files #tool #tools #image #images #trd #ZXSpectrum #BetaDisk #start #Interface1 #ZXSpectrums #emulator #emulators #Pentagon #Scorpion #Evolution #Sprinter #Clone #Variant #Variants #MAME #build #Windows #util #utils #vintage #vintageComputing #substitute #substitutes

@lunte161 @c_merriweather @itsfoss
What my head are these?

Anyway, someone might help…
https://todon.eu/@lunte161/115368325687273863

#Linux #Ubuntu #LinuxNewbies #LinuxTools #LinuxTool #LinuxHelp #newbie #newbies #saveMe #PCs #LinuxNewbie #help #LinuxForum #UbuntuHelp #LinuxMint #ZorinOS #WindowsEOL #MSWindows #Windows10EOL #windows10alternative #Windows10 #Windows11 #Windows10vsWindows11 #tracking #dataCollection #AI #ArtificialIntelligence #privacy #privacyMatters #MicroShit #Windoze #windoze11 #software #WindowsAlternative #WindowsAlternatives #migrate2Linux #MigrateToLinux #seekHelp #dev #devs #Development #developer #developers #develop #edit #extract #inject #files #tool #tools #image #images #trd #ZXSpectrum #BetaDisk #start #Interface1 #ZXSpectrums #emulator #emulators #Pentagon #Scorpion #Evolution #Sprinter #Clone #Variant #Variants #MAME #build #Windows #util #utils #vintage #vintageComputing #substitute #substitutes

I've been waiting for a java BCF2.2 parser in HTSJDK for ~10 years

So I wrote one: https://github.com/lindenb/bcfparser

The BCF specification is quite complicated but it looks like the current tests are passing.

#java #bioinformatics #variant #vcf #bcf

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, https://www.cell.com/heliyon/fulltext/S2405-8440(24)16669-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024166698%3Fshowall%3Dtrue

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, https://www.cell.com/heliyon/fulltext/S2405-8440(24)16669-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024166698%3Fshowall%3Dtrue

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, https://www.cell.com/heliyon/fulltext/S2405-8440(24)16669-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024166698%3Fshowall%3Dtrue

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, https://www.cell.com/heliyon/fulltext/S2405-8440(24)16669-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024166698%3Fshowall%3Dtrue

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, https://www.cell.com/heliyon/fulltext/S2405-8440(24)16669-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024166698%3Fshowall%3Dtrue

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Pipeline release! nf-core/raredisease v2.2.0 - 2.2.0 - Dogmatix!

Please see the changelog: https://github.com/nf-core/raredisease/releases/tag/2.2.0

#diagnostics #rare-disease #snv #structural-variants #variant-annotation #variant-calling #wes #wgs #nfcore #openscience #nextflow #bioinformatics

Structural and molecular #basis of the #epistasis effect in enhanced affinity between #SARS-CoV-2 #KP3 and #ACE2 http://biorxiv.org/cgi/content/short/2024.09.03.610799v1?rss=1

KP.3, featuring F456L and Q493E, exhibits a markedly enhanced ACE2 binding affinity compared to #KP2 and #JN1 #variant due to synergistic effects between these mutations.

Structural and molecular #basis of the #epistasis effect in enhanced affinity between #SARS-CoV-2 #KP3 and #ACE2 http://biorxiv.org/cgi/content/short/2024.09.03.610799v1?rss=1

KP.3, featuring F456L and Q493E, exhibits a markedly enhanced ACE2 binding affinity compared to #KP2 and #JN1 #variant due to synergistic effects between these mutations.

Structural and molecular #basis of the #epistasis effect in enhanced affinity between #SARS-CoV-2 #KP3 and #ACE2 http://biorxiv.org/cgi/content/short/2024.09.03.610799v1?rss=1

KP.3, featuring F456L and Q493E, exhibits a markedly enhanced ACE2 binding affinity compared to #KP2 and #JN1 #variant due to synergistic effects between these mutations.

Structural and molecular #basis of the #epistasis effect in enhanced affinity between #SARS-CoV-2 #KP3 and #ACE2 http://biorxiv.org/cgi/content/short/2024.09.03.610799v1?rss=1

KP.3, featuring F456L and Q493E, exhibits a markedly enhanced ACE2 binding affinity compared to #KP2 and #JN1 #variant due to synergistic effects between these mutations.

Structural and molecular #basis of the #epistasis effect in enhanced affinity between #SARS-CoV-2 #KP3 and #ACE2 http://biorxiv.org/cgi/content/short/2024.09.03.610799v1?rss=1

KP.3, featuring F456L and Q493E, exhibits a markedly enhanced ACE2 binding affinity compared to #KP2 and #JN1 #variant due to synergistic effects between these mutations.

#Influenza #H1N1 #variant virus - #VietNam, #WHO D.O.N.: https://www.who.int/emergencies/disease-outbreak-news/item/2024-DON532

On 19 Aug 24, the VietNam #IHR NFP notified WHO of a laboratory-confirmed #human #infection with a #swine-origin flu H1N1v virus. Patient was a 70-year-old female with underlying medical conditions, from Son La province, a northern mountainous province in VietNam bordering #Lao People’s Democratic Republic... she was transferred to NHTD where she underwent treatment for 6 days but died on 11 Jun.

Immunogenicity and #efficacy of #XBB15 rS #vaccine against the #EG51 #variant of #SARS-CoV-2 in Syrian #hamsters, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00528-24?af=R

Thus, based on these study results, the protein-based XBB.1.5 vaccine is immunogenic and increased the breadth of protection against the Omicron EG.5.1 variant in the Syrian hamster model.

Pipeline release! nf-core/sarek v3.4.4 - Sarek 3.4.4 - Ruopsokjåkhå!

Please see the changelog: https://github.com/nf-core/sarek/releases/tag/3.4.4

#annotation #cancer #gatk4 #genomics #germline #pre-processing #somatic #target-panels #variant-calling #whole-exome-sequencing #whole-genome-sequencing #nfcore #openscience #nextflow #bioinformatics

Rumpel Labs to launch platform for tokenizing airdrop points - The protocol seeks to address longstanding limitations of airdrops. 
... - https://cointelegraph.com/news/rumpel-labs-launch-platform-tokenizing-airdrop-points #venturecapital #dragonfly #variant #airdrop #rumpel #nudge #vc

[Correspondence] Virological #characteristics of the #SARS-CoV-2 #KP311 #variant https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00505-X/fulltext?rss=yes

SARS-CoV-2 #JN1 variant (#BA28611), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted previously predominant #XBB lineages by beginning of 2024. Subsequently, JN.1 subvariants including #KP2 (JN.1.11.1.2) & #KP3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently (appendix pp 19–20).2

[Correspondence] Virological #characteristics of the #SARS-CoV-2 #KP311 #variant https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00505-X/fulltext?rss=yes

SARS-CoV-2 #JN1 variant (#BA28611), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted previously predominant #XBB lineages by beginning of 2024. Subsequently, JN.1 subvariants including #KP2 (JN.1.11.1.2) & #KP3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently (appendix pp 19–20).2

[Correspondence] Virological #characteristics of the #SARS-CoV-2 #KP311 #variant https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00505-X/fulltext?rss=yes

SARS-CoV-2 #JN1 variant (#BA28611), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted previously predominant #XBB lineages by beginning of 2024. Subsequently, JN.1 subvariants including #KP2 (JN.1.11.1.2) & #KP3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently (appendix pp 19–20).2

[Correspondence] Virological #characteristics of the #SARS-CoV-2 #KP311 #variant https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00505-X/fulltext?rss=yes

SARS-CoV-2 #JN1 variant (#BA28611), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted previously predominant #XBB lineages by beginning of 2024. Subsequently, JN.1 subvariants including #KP2 (JN.1.11.1.2) & #KP3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently (appendix pp 19–20).2

An upcoming #vaccine from the biotech co Novavax will target #JN1, a #coronavirus #variant that accounted for the bulk of cases in the #UnitedStates this winter. The Pfizer & Moderna shots coming this fall will target #KP2, a newer offshoot of JN.1 that’s been circulating this summer. The #variants responsible for the largest share of cases in the #US right now, #KP3 & #KP311, are closely related to KP.2 & JN.1.

#health #PublicHealth #medicine #COVID

Pipeline release! nf-core/sarek v3.4.3 - Sarek 3.4.3 - Loametjåhkkå!

Please see the changelog: https://github.com/nf-core/sarek/releases/tag/3.4.3

#annotation #cancer #gatk4 #genomics #germline #pre-processing #somatic #target-panels #variant-calling #whole-exome-sequencing #whole-genome-sequencing #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/raredisease v2.1.0 - 2.1.0 - Obelix!

Please see the changelog: https://github.com/nf-core/raredisease/releases/tag/2.1.0

#diagnostics #rare-disease #snv #structural-variants #variant-annotation #variant-calling #wes #wgs #nfcore #openscience #nextflow #bioinformatics

#Covid19 : trois #questions sur ce nouveau #variant « #XDK » qui se diffuse progressivement en # France https://www.ouest-france.fr/sante/virus/coronavirus/covid-19-trois-questions-sur-ce-nouveau-variant-xdk-qui-se-diffuse-progressivement-en-france-9f5e3e52-fcc0-11ee-9b3d-44ca7a681769?utm_source=fluxpublicfrance&utm_medium=fluxrss&utm_campaign=banquedecontenu

Santé publique France surveille depuis février dernier un nouveau variant du Covid-19. Baptisé « XDK », ce virus a été détecté dans plus de 20 % des échantillons observables dans l’Hexagone et laisse craindre un regain de l’épidémie à l’approche de l’été. Que risque-t-on ? On vous répond.