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#naturemedicine — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #naturemedicine, aggregated by home.social.

  1. Bedeutende #Forschung in der Geburtsmedizin: Erstmals wurde eine #Therapie der #Schwangerschaftsvergiftung erfolgreich an Patientinnen erprobt. Eine spezielle Blutwäsche entfernt das krankheitsauslösende Protein. „Das ist ein wichtiger Schritt hin zu einer ursächlichen Therapie der Präeklampsie" sagt Prof. Holger Stepan von der Universitätsmedizin Leipzig. Die Ergebnisse der Studie wurden in #NatureMedicine veröffentlicht. uni-leipzig.de/newsdetail/arti

    #Präeklampsie #Forschung #UniLeipzig #Medizin

  2. Il 2024 è stato l'anno più caldo mai registrato. In Europa nei mesi estivi decine di migliaia di vittime: al primo posto noi italiani

    Uno studio di #ISGlobal stima che i morti a causa del caldo dall'1/6 al 30/9 siano stati 62.775, il 23,6% in più del 2023. I risultati sono su #NatureMedicine.
    Al primo posto per decessi per le alte temperature estive noi italiani, con oltre 19.000 persone decedute, poi spagnoli, 6.700, Germania (6.300) e Grecia (6.000).

    nature.com/articles/s41591-025

    @salute

  3. Whoa

    A new study shows that #microplastics are making their way into human #brains —w/potentially dangerous effects on people’s #health & mental #acuity.

    A paper published Mon in #NatureMedicine found that the tiny fragments of #plastic are passing the blood-brain barrier & into human brains, & the amount of #microplastics in the #brain appears to be increasing over time. There were 50% more fragments in brains analyzed in 2024 than in 2016.

    #science #medicine #climate
    washingtonpost.com/climate-env

  4. I wrote about RSV vaccines in my #NatureMedicine column in February.
    Very good news this week with the FDA approval of GSK's RSV vaccine for adults 60 and over - it's the first approved RSV vaccine.

    edition.cnn.com/2023/05/03/hea

    Several other candidate RSV vaccines are at a late stage of development, including mRNA based vaccines. The next big thing to watch for are those seeking to protect newborns and infants by maternal immunisation.

    #RSV #Vaccine #RespiratoryVirus #drugdevelopment #Pharma #Immunology

    nature.com/articles/d41591-023

  5. The FDA has approved Biogen's ALS drug, Tofersen, an antisense oligo targeting SOD1. I wrote about this back in September in my Clinical Pipeline column as part of a shift towards approving drugs based on biomarkers without clear signs of clinical efficacy*.

    nature.com/articles/d41591-022

    *You can have a look at the trial data in NEJM, in a study that concluded that "In persons with SOD1 ALS, tofersen reduced concentrations of SOD1 in CSF and of neurofilament light chains in plasma over 28 weeks but did not improve clinical end points and was associated with adverse events."

    lnkd.in/dwGMYGgh

    #NatureMedicine #amyotrophiclateralsclerosis #drugdevelopment #pharma

  6. My latest Clinical Pipeline column for #NatureMedicine, on fitusiran, a small interfering RNA for the treatment of hemophilia A or B. It may be particularly useful for patients with inhibitors (antibodies against clotting factors).

    #drugdevelopment #drugdiscovery #SciComm #sciencecommunication #pharma #hemophilia 👇

    nature.com/articles/d41591-023

  7. 'Using two independent real-world datasets from three different countries and an independent validation cohort based on the global, double-blind, placebo-controlled, phase 3 RECOURSE trial, we demonstrate that codon-specific KRAS mutations predict OS benefit for patients treated with the chemotherapeutic agent FTD/TPI in late-stage mCRC.'

    #NatureMedicine #KRAS #PrecisionMedicine

    nature.com/articles/s41591-023

  8. #HIV patient #cured after bone marrow transplant in rare case

    A man in Germany who had been diagnosed w/HIV has been declared free of the virus after receiving HIV-resistant stem cells through a bone marrow transplant intended to treat leukemia. Acc/to research published in the journal #NatureMedicine on Mon, the man was monitored for >9 yrs after the 2013 transplant, & there is now “strong evidence” that he has been cured.

    washingtonpost.com/health/2023

  9. My latest Clinical Pipeline column for #NatureMedicine is out, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
    #Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody

    nature.com/articles/d41591-023

  10. My latest Clinical Pipeline column for #NatureMedicine is out today, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.

    #Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody

    nature.com/articles/d41591-023

  11. My latest clinical pipeline column for Nature Medicine is a look at a drug recently approved by the #FDA to delay the onset of type 1 diabetes.

    It's a direct descendant of the very first monoclonal ever approved for clinical use.

    #Diabetes #Type1Diabetes #DrugDevelopment #DrugDiscovery #NatureMedicine #Immunology #MonoclonalAntibody

    nature.com/articles/d41591-022

  12. Gathering real world data on the efficacy of drugs and vaccines used to treat or prevent #monkeypox is vital. Many where developed for #smallpox and approved via the FDA's "animal rule", which means that although the safety data is there, the efficacy is essentially unknown. I wrote a bit about this for #NatureMedicine in September when looking at the use of the #antiviral #tecovirimat for monkeypox.

    nature.com/articles/d41591-022

  13. My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

    The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

    #IDMastodon #DrugDevelopment
    #antibioticresistance

    nature.com/articles/d41591-022

  14. A.I. Comes to the Operating Room - Images made by lasers and read by computers can help speed up the diagnosis of brain tumors during... more: nytimes.com/2020/01/06/health/ #laser(lightamplificationbystimulatedemissionofradiation) #naturemedicine(journal) #artificialintelligence #your-feed-healthcare #surgeryandsurgeons #daniela.orringer #tissue(human) #braincancer #tumors