#neuralcircuits — Public Fediverse posts

DATE: August 23, 2026 at 11:15AM
SOURCE: SCIENCE DAILY PSYCHOLOGY FEED

TITLE: A major Alzheimer’s risk gene may shrink brain cells years before symptoms

URL: https://www.sciencedaily.com/releases/2026/08/260821012234.htm

Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimer’s progresses.

URL: https://www.sciencedaily.com/releases/2026/08/260821012234.htm

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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #AlzheimersDisease #APOE4 #Nell2 #BrainHealth #Neuroscience #MemoryLoss #EarlyDetection #MouseModel #GeneTherapy #NeuralCircuits

I am happy announce that our manuscript preprint from my PhD work at @kofanchen lab is now available.
(https://www.biorxiv.org/content/10.64898/2026.05.27.728351v1)
My research (and this manuscript) focuses on investigating the role oculocutaneous albinism-associated genes in regulating sleep and circadian rhythm. I am further focusing on one of the genes reported here (lovit), and how it regulates sleep. Another interesting manuscript to follow soon.
#sleep
#circadian
#neuralcircuits
#drosophila

@kofanchen
I am happy announce that our manuscript preprint from my PhD work is now available.

https://www.biorxiv.org/content/10.64898/2026.05.27.728351v1

My research (and this manuscript) focuses on investigating the role oculocutaneous albinism-associated genes in regulating sleep and circadian rhythm. I am further focusing on one of the genes reported here (lovit), and how it regulates sleep. Another interesting manuscript to follow soon.
#sleep
#circadian
#neuralcircuits
#drosophila

🧠 New paper by Phillips et al: #Neuroplex combines #miniscope #CalciumImaging with multiplexed #SpectralImaging through the same #GRINlens, allowing up to 9 projection-defined #NeuronalPopulations to be identified in freely #behaving mice. Instead of measuring activity alone, the approach links #FunctionalDynamics directly to circuit identity within the same animal and behavioral session.

📝 https://doi.org/10.7554/eLife.110277

#Neuroscience #CompNeuro #NeuralCircuits #Imaging @eLife https://fediscience.org/@eLife/116589668668928682

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=4064

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=2839

Postdoc position in Neurobiology
Biology Institute of the Ecole Normale Supérieure (IBENS)

We are recruiting 2 posdtocs in #Ineurobiology. Come and join us at #IBENS in Paris

See the full job description on jobRxiv: https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/

#neuralcircuits #neurobi...
https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/?fsp_sid=2174

Postdoc position in ultrasound neuromodulation at UCSF
University of California San Francisco

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/

#neuralcircuits #neuroengineering #neuromodulation #systemsneuroscience #ultrasound #Science...
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoc-position-in-ultrasound-neuromodulation-at-ucsf-2/?fsp_sid=1831

Postdoc position in Neurobiology
Biology Institute of the Ecole Normale Supérieure (IBENS)

We are recruiting 2 posdtocs in #Ineurobiology. Come and join us at #IBENS in Paris

See the full job description on jobRxiv: https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/

#neuralcircuits #neurobi...
https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/?fsp_sid=1166

Postdoc position in Neurobiology
Biology Institute of the Ecole Normale Supérieure (IBENS)

We are recruiting 2 posdtocs in #Ineurobiology. Come and join us at #IBENS in Paris

See the full job description on jobRxiv: https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/

#neuralcircuits #neurobio...
https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/?fsp_sid=592

Postdoc position in Neurobiology
Biology Institute of the Ecole Normale Supérieure (IBENS)

We are recruiting 2 posdtocs in #Ineurobiology. Come and join us at #IBENS in Paris

See the full job description on jobRxiv: https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/

#neuralcircuits #neurobio...
https://jobrxiv.org/job/biology-institute-of-the-ecole-normale-superieure-ibens-27778-postdoc-position-in-neurobiology/?fsp_sid=431

Inside the Brain: Exploring Neurotransmitters, Pathways, and Neuroimmune Interactions

#BrainChemistry #Neuroscience #Neurotransmitters #NeuralCircuits #Dopamine #Serotonin #Neuroinflammation #Neurodegeneration #BrainHealth #Neuroplasticity

https://youtube.com/shorts/77NzBEJ6qqI?feature=share

From Blueprints to Signals: Understanding Phenotypes and Endophenotypes in Neuroscience

#Neuroscience #BrainAndBehavior #MentalHealth #BrainMapping #NeuralCircuits #EmotionAndMemory #MentalDisorders #BrainRegions #CognitiveScience #MindAndBehavior

https://youtube.com/shorts/J_pQyOQdeLQ?feature=share

The Science of Empathy: Neural Pathways that Connect Us

#EmotionalContagion #Neuroscience #MirrorNeurons #Empathy #BrainScience #EmotionalIntelligence #MentalHealth #NeuralCircuits #Psychology #HumanConnection

https://youtube.com/shorts/jck-A6kXsXk?feature=share

Journey Through the Brain: Exploring the Neural Networks That Power Our Thoughts, Emotions, and Behaviors

#BrainScience #Neuroscience #BrainTour #MindAndBody #BrainNetworks #NeuralCircuits #HumanBrain #BrainAwareness #CognitiveScience #EmotionalIntelligence #NeuroscienceEducation #BrainFunction #MindExploration

https://youtube.com/shorts/vqAb9cN7ae0?feature=share

AI brain map could help demystify Alzheimer’s and autism | Neuroscience | The Guardian
https://www.theguardian.com/science/article/2024/may/30/neuroscientists-ai-brain-map-alzheimers-autism

#Alzheimers
#Autism
#Neurodiversity
#NeuralCircuits
#Neuroscience
#Neurodivergence
#TraumaticBrainInjury
#AuditoryDevelopmentAndConnectomicsLab
#VR
#AI
#BrainsEarlyDevelopment
#CalyxOfHeld
#SouthFloridaUni
#AuditoryDysfunction
#MedicalEngineering
#Spirou
#BrainMapping

Eye movement reflex reveals genetic association with autism
https://www.msn.com/en-gb/health/other/eye-movement-reflex-reveals-genetic-association-with-autism/ar-BB1j0QQ3?cvid=b1584213849a4ab0a95a80fd09404219&ocid=winp2fptaskbarhover&ei=16

#Autism
#EyeMovement
#Genes
#Genetics
#SCN2AGene
#VOR
#VestibuloOcularReflex
#UCFSWeillInstituteForNeuroscience
#NeuralCircuits
#NeuralNetworks
#Cerebellum
#CRISPR

On Monday, there will be a talk on how to simulate a #connectome: discover the potential of connectivity measurements in predicting #neuralactivity and advancing our understanding of #neuralcircuits, by Srini Turaga:

📍 University of #Bonn
⏰ June 19, 2023, 12 pm CET
🌍 email at [email protected] for Zoom meeting details

#compneuro #computationalneuroscience #neuroscience

Wiring map reveals how larval fruit fly brain converts sensory signals to movement

https://www.spectrumnews.org/news/wiring-map-reveals-how-larval-fruit-fly-brain-converts-sensory-signals-to-movement/

#neuralcircuits #animalmodels #brainmapping #connectivity #Drosophila #dendrites #circuits #learning #synapses #autism #axons #News

Serotonin initiates earliest social bonds

https://www.spectrumnews.org/news/serotonin-initiates-earliest-social-bonds/

#sensoryperception #neuralcircuits #animalmodels #mousemodels #serotonin #oxytocin #News #rats

Tweaks to autism-linked pathway tilt circuits’ signaling balance

https://www.spectrumnews.org/news/tweaks-to-autism-linked-pathway-tilt-circuits-signaling-balance/

#inhibitorysignaling #tuberoussclerosis #neuralcircuits #interneurons #circuits #synapses #autism #News #TSC2

Missing mechanism helps solve fragile X protein mystery

https://www.spectrumnews.org/news/missing-mechanism-helps-solve-fragile-x-protein-mystery/

#intellectualdisability #repetitivebehaviors #socialdifficulties #fragileXsyndrome #neuralcircuits #connectivity #hippocampus #mousemodels #treatments #synapses #autism #News #FMR1 #FMRP

This summer school looks pretty cool.
https://tenss.ro/index.php

#neuroscience #summerschool #systemsneuroscience #electrophysiology #opticalimaging #neuralcircuits

Hello synapse.cafe!

Just migrated from sciencemastodon, a perfectly good instance, but I think this will feel a little more like home. Anyway, #introduction time again!

I’m an assistant #professor at the University of Manitoba in #Winnipeg. I run the #Invertebrate #Neuroethology #Laboratory, where we study #AnimalBehavior, #Neuroscience, and #BehavioralEcology. We are interested in the #NeuralCircuits of #Learning, #Memory, and #DecisionMaking, especially with respect to #TimeMemory, other areas of #Chronobiology, and #MultisensoryIntegration. We work mostly with #HoneyBees (#Apis #mellifera), but we like all #inverts!

Neural manifold analysis of brain circuit dynamics in health and disease. Mitchell-Heggs, Prado et al, JCNS 2022.

https://link.springer.com/article/10.1007/s10827-022-00839-3

#neuroscience #neuralmanifolds #compneuro #neuralcircuits