#plasticity — Public Fediverse posts

Primary and higher-order thalamic nuclei make distinct contributions to cortical reorganization in congenital sensory loss https://www.biorxiv.org/content/10.64898/2026.08.05.743029v1 #LGN #plasticity #neuroscience

Autism, Structure, and the Malleable Brain: What Restoring Function to Old Circuits Tells Us About New Therapies

Stay curious — follow @1ban_news.

https://1ban.news/rapamycin-autism-functional-plasticity/

#1ban #rapamycin #autism #functional #plasticity #science

Look what’s now possible: Novel wire-free & waterproof #Miniscope (1P) in the #MorrisWaterMaze 👌

📄 https://www.biorxiv.org/content/10.64898/2026.07.13.734058v1
(#NMDA receptor-dependent #Hebbian #plasticity refines #hippocampal spatial representations during two-dimensional navigation learning, Reshef et al)

Btw they used balloons to keep the mouse‘ head above water level: "3 Mylar spherical helium-filled balloons…were used to reduce the weight load on the animal’s head to avoid sinking." Hackers ✌️

#Neuroscience #Behavior #MWM

Complex three-dimensional rearing environments amplify compensatory plasticity following early blindness (in short-tailed opossums) https://www.eneuro.org/content/early/2026/07/02/ENEURO.0059-26.2026 Try visual-to-auditory sensory substitution to supplement tactile feedback? #crossmodal #plasticity #neuroscience

The rewiring brain: How neuroscience is rethinking stroke recovery 💤

https://1ban.news/stroke-recovery-neural-plasticity-mechanisms/
#neuroscience #stroke #recovery #brain #health #plasticity

The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science "Mind-bending, miracle-making, reality-busting stuff" $18 to $1.99 Norman Doidge M.D. 4.7/5 (5,556 Reviews) #neuroscience #plasticity #books #cognitive #psychology #science #booksky #learning #health

The Brain That Changes Itself:...

How does the structure of the human #brain change during #learning? This study by Griffa, Huang, Della-Maggiore &co shows that learning induces both transient and sustained changes in neuronal morphology, consistent with structural #plasticity

https://plos.io/3SgWogV

Cross-modal training reduced susceptibility to the sound-induced flash illusion and generalized across stimulus onset asynchronies https://link.springer.com/article/10.1007/s00426-026-02321-6 Can one also train for *increased* SiFI susceptibility? #SiFI #multisensory #plasticity

By linking up visual and auditory processing in the human brain, The vOICe vision BCI can act as both a fully noninvasive visual prosthesis for the totally blind and as a research vehicle for macroscopic neuroscience https://www.artificialvision.com/neuralink.htm #crossmodal #plasticity #BrainStates

Short-term #synaptic #plasticity (#STP) transiently modulates synaptic strength based on recent activity. #ShortTermDepression #STD reduces efficacy during repeated activity, while #ShortTermFacilitation #STF can enhance responses to closely spaced #spikes. These dynamics shape #NeuralProcessing, #filtering, and synaptic #homeostasis. Here's a short #Python implementation and simulation in #NESTSimulator:

🌍 https://www.fabriziomusacchio.com/blog/2026-05-25-std_and_stf/

#CompNeuro #Neuroscience #NeuralDynamics #TsodyksMarkramModel

2/
• The Evolutionary Flow: Traces the progression from genotype through developmental plasticity to the behavioral phenotype. This phenotype is tested by natural selection; successful traits lead to allele frequency shifts in a population.

https://youtu.be/SPWd6CjrJd8

#animals
#ethology
#genotype
#plasticity
#phenotype
#allele
#instinct
#evolution

Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes"; #neuroscience #brain #plasticity

When synaptic #plasticity depends on more than spike timing alone, the #ClopathRule offers a biologically plausible model incorporating postsynaptic voltage dynamics. This voltage based #STDP model captures #synaptic change features such as frequency dependence and homeostatic stabilization making it useful for simulating #learning and #memory in #NeuralNetworks. Here's a brief introduction to that rule and its applications in #CompNeuro:

🌍 https://www.fabriziomusacchio.com/blog/2026-04-14-clopath_rule/

#Neuroscience

@MaFu55 #CX3CR1 deficiency enhances microglial reactivity while limiting GB cell migration, and CSF1R inhibition also constrains #tumor microtube #plasticity. Together, the data place #microglia directly in the control of #glioblastoma invasion dynamics.

Huge congrats to Felix and all co-authors! 🥳

@dzne #DZNE

🧠 New paper from the @MaFu55 lab! 🥳

Felix shows that #microglia shape #glioblastoma invasion at the far infiltration zone. Using in vivo #3photon #imaging, he finds dynamic microglial responses, and shows that microglial manipulation reduces GB migration and limits #tumormicrotube #plasticity.

📝 https://doi.org/10.1016/j.immuni.2026.03.010

#Neuroscience 🧪 @dzne #3P

Our recent paper 📜 ( see https://fediscience.org/@idealab/116284938212580094 ) was well received in national and international press. We were featured not only by the press department of Bielefeld University ( https://aktuell.uni-bielefeld.de/2026/03/25/why-no-individual-is-like-another/ ) but also by the German Federal Ministry of Research, Technology and Space ( https://www.research-in-germany.org/idw-news/en_US/2026/3/2026-03-25_Why_No_Individual_Is_Like_Another.html ) and by the American popular science magazine Nautilus ( https://nautil.us/the-science-behind-being-one-of-a-kind-1279329 ).

#genetics #epigenetics #ecology #nautilus #evolution #plasticity #AcademicMastodon @academicchatter

I have a bad feeling about this, perhaps this is the end of #Plasticity 3D support for Linux. I hope I’m wrong, but this could be the last year. 🥶 #CAD #Linux
Sometimes bad things happens, and this isn't the worst..👋

@DenisMeuthen , PI of the @idealab , contributed to an opinion paper 📜 in Trends in Ecology and Evolution ( @TrendsEcolEvo ) . In this paper, we hypothesize that niche processes (niche choice, niche construction, niche conformance) and epigenetic variation are causally and bidirectionally linked. Studying this bidirectional causal relationship will deepen our understanding of the proximate mechanisms underlying individualization and elucidate how epigenetic variation arises, persists, and contributes to evolution. You can access the full paper here: https://authors.elsevier.com/sd/article/S0169-5347(25)00370-2

#genetics #epigenetics #ecology #evolution #plasticity #AcademicMastodon @academicchatter

The Urbanczik-Senn plasticity model is a powerful framework for understanding synaptic #plasticity in #NeuralNetworks. It integrates dendritic prediction errors to unify supervised, unsupervised, and #ReinforcementLearning under a single rule. Its predictive coding mechanism and robust learning dynamics make it valuable for simulating neural processing and exploring plasticity. Here’s a short simulation using the #NESTsimulator:

🌍 https://www.fabriziomusacchio.com/blog/2026-02-22-urbanczik_senn_plasticity/

#CompNeuro #Neuroscience

Spike-timing-dependent #plasticity (#STDP) is a core rule in #ComputationalNeuroscience that adjusts #synaptic strength based on precise pre- vs. postsynaptic #spike timing, enabling #TemporalCoding and #learning in #SNN. In this post, I summarize its mathematical formulation, functional consequences for learning and #memory along with a simple #Python example:

🌍 https://www.fabriziomusacchio.com/blog/2026-02-12-stdp/

#CompNeuro #Neuroscience #SNN #NeuralDynamics #NeuralPlasticity

#NeuralPlasticity & #learning are distinct but interrelated processes. #Plasticity denotes biological change in #NeuralSystems, while learning is its functional expression in #NetworkDynamics & #behavior. Learning arises from coordinated plastic processes, reshaping #NeuralStateSpace & #attractors to support stable yet flexible representations. Here's a new post on these concepts & their implications for #ComputationalNeuroscience:

🌍https://www.fabriziomusacchio.com/blog/2026-02-02-neural_plasticity_and_learning/

#CompNeuro #Neuroscience

Incorporating structural #plasticity in #SpikingNeuralNetworks (#SNN) enables dynamic #synaptic connectivity, reflecting the #brain's adaptability. By modeling synaptic growth and pruning based on #calcium concentration, we can simulate processes such as #learning and #MemoryFormation. In this post, I reproduce the #NESTSimulator tutorial on structural plasticity, demonstrating its impact on network stability and #homeostasis:

🌍 https://www.fabriziomusacchio.com/blog/2026-02-01-structural_plasticity/

#CompNeuro #Neuroscience #NeuralNetworks

🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.

Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.

🌍 https://doi.org/10.7554/eLife.109538.1

#Neuroscience #CompNeuro #SynapticPlasticity

🧠 New paper from our neighboring Gründemann Lab @dzne 👋

Chloé Maëlle Benoit and colleagues show that #axon initial segments in #mPFC #neurons undergo #learning-dependent #StructuralPlasticity during fear extinction, linking #AIS dynamics to #MemoryFormation in vivo. A very cool study that extends the concept of learning-related #plasticity beyond #synapses to intrinsic neuronal compartments.

🌍 https://doi.org/10.1038/s41593-025-02152-5

#Neuroscience #DZNE