#nlrp3 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nlrp3, aggregated by home.social.
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Polyphenol-rich extra-virgin olive oil influences bioenergetics and may modulate NLRP3 inflammasome in PBMCs from children and adolescents with obesity https://www.diningandcooking.com/2753832/polyphenol-rich-extra-virgin-olive-oil-influences-bioenergetics-and-may-modulate-nlrp3-inflammasome-in-pbmcs-from-children-and-adolescents-with-obesity/ #biochemistry #CellBiology #ChildrenObesity #diseases #Endocrinology #ExtraVirginOliveOil #HumanitiesAndSocialSciences #Inflammasome #MedicalResearch #Mediterranean #MediterraneanOliveOil #Mitochondria #multidisciplinary #NLRP3 #Olive #OliveOil #PBMCs #physiology #polyphenols #science
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#MARCH5-dependent #NLRP3 #ubiquitination is required for #mitochondrial NLRP3-NEK7 complex formation and NLRP3 #inflammasome activation
https://www.embopress.org/doi/full/10.15252/embj.2023113481 -
Which #immune pathways (beyond #TLRs) control #otitis media and #COPD-inducing #Moraxella catarrhalis #infection?
Si-Ming Man and colleagues from Australian National University reveal requirement for #guanylate-binding GBP proteins and #caspase11-#NLRP3 #inflammasomes
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'Gefitinib (GF), the tyrosine kinase inhibitor (TKI) targeting epidermal growth factor receptor, initiates lung #inflammation through the NLR family pyrin domain containing 3 (NLRP3) inflammasome. However, the molecular targets and mechanisms underlying the inflammatory action of GF remain unknown. In this study, we identified mitochondrial Src family kinases (mSFKs) as key determinants of GF-induced #NLRP3 #inflammasome activation.'