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#gut-brainaxis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #gut-brainaxis, aggregated by home.social.

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  1. Microbiota alterations leading to amino acid deficiency contribute to depression in children and adolescents [2025]
    pmc.ncbi.nlm.nih.gov/articles/

    "Our findings highlight that gut microbiota alterations contribute to AAs deficiency, particularly lysine, which plays a crucial role in MDD pathogenesis in children and adolescents. "

    #depression #GutMicrobiome #lysine #GutBrainAxis

  2. Fascinated by the whole gut/brain axis thing ... and to learn that my morning coffee may* actually support the microbiome makes me very happy 😁

    *findings are tentative, as the article makes clear

    #coffee #gutbrainaxis #research #happy #microbiome

    psypost.org/scientists-discove

  3. NF1 research breakthrough sparks hope for simple, affordable therapies

    📰 Original title: Zoe Petropoulos hopeful following breakthrough in neurofibromatosis research

    🤖 IA: It's not clickbait ✅
    👥 Users: It's not clickbait ✅

    View full AI summary en.killbait.com/nf1-research-b

    #health #neurofibromatosis #nf1 #gutbrainaxis

  4. Wenn wir beim Gehen bewusst an Themen arbeiten, passiert mehr als „nur Denken“: Rhythmischer Schritt, Naturreize und der Tagtraum-Modus des Gehirns beruhigen das Nervensystem, Dauerstress sinkt – das entlastet auch unseren Darm und schafft ein günstigeres Milieu für ein resilienteres Mikrobiom.
    Gehen + emotionale Verarbeitung = weniger Stresslast im ganzen System.
    #gehenunddenken #gehmeditation #gutbrainaxis #mikrobiom #resilienz #mentalhealth #embodiment #naturewalks

  5. 🧠 Could gut metabolites hold the key to enhancing antidepressant effects?

    🔗 Does isovaleric acid play a key role in the interaction between probiotics and antidepressants? A secondary analysis of a randomized clinical trial. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.05

    📚 CSBJ: csbj.org/

    #GutBrainAxis #MentalHealth #Probiotics #DepressionResearch #Psychobiotics #Microbiome

  6. 🧠 A new review in Nutrients links anxiety to gut microbiota imbalances—like reduced diversity & fewer short-chain fatty acid-producing bacteria. Probiotics may help ease symptoms by supporting gut health. #GutBrainAxis #Probiotics #MentalHealth #RDNsLead #NutritionScience medicalnewstoday.com/articles/

  7. Interesting if true: Vagus nerve innervation (controlled by BLA?) to Brunner's glands in the duodenum control the hospitability of the gut to lactobacillus. Ablating the glands renders the gut susceptible to dysbiosis.

    An Amygdalar-Vagal-Glandular Circuit Controls the Intestinal Microbiome
    Chang et al., preprint at biorxiv 2024
    doi.org/10.1101/2024.06.02.594

    #neuroscience #vagusnerve #gutbrainaxis #gut_microbiome

  8. "Taken together, our study demonstrates that members of the Bacteroidota phylum contribute to AD pathogenesis by suppressing microglia phagocytic function, which leads to impaired Aβ clearance and accumulation of amyloid plaques."

    Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models
    Wasén et al., Nature Communications 2024
    doi.org/10.1038/s41467-024-476

    #neuroscience #gutbacteria #microbiome #microglia #gutbrainaxis

  9. Looking forward to presenting our (@SimonMcArthur) work on methylphenols and the gut-brain axis at the 4th International World of Microbiome Conference, today in Sofia.

    TL;DR - p-cresol glucuronide protective against LPS; p-cresol sulfate very bad if you've got chronic kidney disease.

    pCG - pubmed.ncbi.nlm.nih.gov/355965
    pCS - biorxiv.org/content/10.1101/20

    #gutbrainaxis #microbiome #metabolites

  10. review article from 2022:

    Gut power: Modulation of human amyloid formation by amyloidogenic proteins in the gastrointestinal tract
    doi.org/10.1016/j.sbi.2021.07.

    "The most common allergen in fish, the highly abundant protein β-parvalbumin (PV), forms amyloids that escape gastrointestinal degradation and transit to the blood [34,35]. PV is a small, calcium-binding protein with a helical structure that transforms to amyloids on calcium removal. Because fish is generally considered beneficial toward age-related diseases such as dementia and Alzheimer's disease, we speculated that an explanation would be cross-reactivity of PV amyloids with human amyloidogenic proteins [36∗∗]. Indeed, in vitro experiments showed that PV amyloids readily blocked aS amyloid formation. "

    "In addition to fish, other food products contain protein amyloids that are not fully digested in the gut: for example, whey and casein proteins (milk), ovalbumin, lysozyme and ovotransferrin (egg), bovine serum albumin and hemoglobin (blood), and glutelin (wheat) [20]."

    The 'Conclusions and outlook' section is very much worth reading, but a bit too long to cut and paste.

    #Parkinsons #neurodegeneration #Food #FoodScience #health #GutBrainAxis #GutMicrobiome

  11. @silask Thanks for sharing, this is a) a very cool cool study, and b) scary if true.

    If true, then those bacteria have been sitting in plain sight in many brain samples and have never been properly studied (or rejected as surgery artefacts). Should be relatively straightforward to replicate in quite a few labs.

    #neuroscience #gutbrainaxis #vagusnerve #neuroinflammation

  12. Very proud of Sameer Alladin, who just published the first preprint of his PhD! It's on proto-#nausea: that slightly funny feeling you get in your #stomach when you experience #disgust!

    If you're interested in #Affect, #Emotion, #Interoception, and/or the #gutbrainaxis, you might enjoy it.

    Read it here: doi.org/10.5281/zenodo.8283453