#metabolomics — Public Fediverse posts

New co-authored manuscript on liver cancer multi-omics:

Integrated Multi-omic Analyses Reveal Novel Gene-Metabolite Relationships in Human Steatohepatitic Hepatocellular Carcinoma
Anspach et al., https://www.jlr.org/article/S0022-2275(26)00107-0/fulltext

8 patients, *paired samples* of cancer and adjacent normal!! (made the statistics so nice to work with and look for correlations between rna-seq and metabolomics).

#Bioinformatics #Metabolomics #RNASeq

Why has GC-MS (gas chromatography- electron impact ioniation- mass spectrometry) had such enduring value for the field of metabolomics? How do we identify metabolites based on mass spectrometry data?

I hope you'll enjoy this video explaining the basics of GC-MS and the spectral library methods we use for explaining these spectra!

https://www.youtube.com/watch?v=vTWXkHPHEI0
#bioinformatics
#metabolomics #GCMS

Postdoctoral Analytical Chemist
Johns Hopkins University

Come join us at Johns Hopkins Malaria Research Institute as an #Analytical Chemistry Postdoc

See the full job description on jobRxiv: https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/

#AnalyticalMethodDevelopment #analyticalmethods #GCMS #LCMS #metabolomics #ScienceJobs #hiring #research
https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/?fsp_sid=4120

Postdoctoral Analytical Chemist
Johns Hopkins University

Come join us at Johns Hopkins Malaria Research Institute as an #Analytical Chemistry Postdoc

See the full job description on jobRxiv: https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/

#AnalyticalMethodDevelopment #analyticalmethods #GCMS #LCMS #metabolomics #ScienceJobs #hiring #research
https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/?fsp_sid=2496

Postdoctoral Analytical Chemist
Johns Hopkins University

Come join us at Johns Hopkins Malaria Research Institute as an #Analytical Chemistry Postdoc

See the full job description on jobRxiv: https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/

#AnalyticalMethodDevelopment #analyticalmethods #GCMS #LCMS #metabolomics #ScienceJobs #hiring #research
https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/?fsp_sid=1523

Postdoctoral Analytical Chemist
Johns Hopkins University

Come join us at Johns Hopkins Malaria Research Institute as an #Analytical Chemistry Postdoc

See the full job description on jobRxiv: https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/

#AnalyticalMethodDevelopment #analyticalmethods #GCMS #LCMS #metabolomics #ScienceJobs #hiring #research
https://jobrxiv.org/job/johns-hopkins-university-27778-postdoctoral-analytical-chemist/?fsp_sid=368

#Leaf-dwelling #fungi enhance black #poplar chemical defenses and mediate multi-trophic #insect interactions.

#Cladosporium #predation #herbivore #alkaloids #stachydrine #metabolomics #microbiome

https://phys.org/news/2025-02-leaf-fungi-black-poplar-chemical.html

Scientists elucidate #molecular mechanisms behind #dinoflagellate #cyst #dormancy.

#cDNA #DinoSL #genomics #metatranscriptome #hormones #ABA #GA #metabolomics

https://phys.org/news/2025-02-scientists-elucidate-molecular-mechanisms-dinoflagellate.html

A Metabolomics Study of Feces Revealed That a Disturbance of Selenium-Centered Metabolic Bioprocess Was Involved in Kashin–Beck Disease, an Osteoarthropathy Endemic to China. https://doi.org/10.3390/nu15214651 #Kashin–BeckDisease #Metabolomics #Intestine #Selenium #LipidMetabolism

Mark your calendars: registration & abstract submissions open on Dec 1, 2023 for our #HavingIMPACTT2024 symposium! Head to our website for details, and don't forget to sign up for updates so you don't miss out: https://www.impactt-microbiome.ca/having-impactt-2024-symposium/

#microbiome #microbiota #symposium #conference #research #datascience #health #bioinformatics #biology #multiomics #metabolomics #proteomics #transcriptomics #cancer #gutbrainaxis #immunology #science #

I spent SO MANY HOURS in grad school manually adjusting peak baselines and deciding what should or shouldn't count as a peak and then going back and doing it all again because I called it a peak in one sample but not the other. I'm SO happy that progress is being made on this problem and very excited to read this preprint!

https://www.biorxiv.org/content/10.1101/2023.07.28.551024v1

#GCMS #LCMS #XCMS #AnalyticalChemistry #Chromatography
#Metabolomics