#ocd — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #ocd, aggregated by home.social.
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Obsessive-compulsive disorder is a complex, heterogeneous neurobiological condition driven by structural, genetic, and neurochemical dysregulation, defined by the presence of intrusive, ego-dystonic obsessions and repetitive, time-consuming compulsions.
#WhatIs #PsychiatricNeuroscience #Neurobiology #MolecularGenetics #Immunology #BiomedicalEngineering #OCD #sflorg
https://www.sflorg.com/2026/08/wi08102601.html -
Obsessive-compulsive disorder is a complex, heterogeneous neurobiological condition driven by structural, genetic, and neurochemical dysregulation, defined by the presence of intrusive, ego-dystonic obsessions and repetitive, time-consuming compulsions.
#WhatIs #PsychiatricNeuroscience #Neurobiology #MolecularGenetics #Immunology #BiomedicalEngineering #OCD #sflorg
https://www.sflorg.com/2026/08/wi08102601.html -
Obsessive-compulsive disorder is a complex, heterogeneous neurobiological condition driven by structural, genetic, and neurochemical dysregulation, defined by the presence of intrusive, ego-dystonic obsessions and repetitive, time-consuming compulsions.
#WhatIs #PsychiatricNeuroscience #Neurobiology #MolecularGenetics #Immunology #BiomedicalEngineering #OCD #sflorg
https://www.sflorg.com/2026/08/wi08102601.html -
Obsessive-compulsive disorder is a complex, heterogeneous neurobiological condition driven by structural, genetic, and neurochemical dysregulation, defined by the presence of intrusive, ego-dystonic obsessions and repetitive, time-consuming compulsions.
#WhatIs #PsychiatricNeuroscience #Neurobiology #MolecularGenetics #Immunology #BiomedicalEngineering #OCD #sflorg
https://www.sflorg.com/2026/08/wi08102601.html -
Obsessive-compulsive disorder is a complex, heterogeneous neurobiological condition driven by structural, genetic, and neurochemical dysregulation, defined by the presence of intrusive, ego-dystonic obsessions and repetitive, time-consuming compulsions.
#WhatIs #PsychiatricNeuroscience #Neurobiology #MolecularGenetics #Immunology #BiomedicalEngineering #OCD #sflorg
https://www.sflorg.com/2026/08/wi08102601.html -
PURE, série courte (6 x 36min) qui traite des TOC sexuels .
Une bonne comédie dramatique adaptée d'une histoire vraie.
Bien jouée et touchante.https://www.arte.tv/fr/videos/103431-001-A/pure-1-6/
#pure #pureO #TOC #reellife #OCD #sexe #sex #penséesIntrusive #viereelle
#arte #BBC -
PURE, série courte (6 x 36min) qui traite des TOC sexuels .
Une bonne comédie dramatique adaptée d'une histoire vraie.
Bien jouée et touchante.https://www.arte.tv/fr/videos/103431-001-A/pure-1-6/
#pure #pureO #TOC #reellife #OCD #sexe #sex #penséesIntrusive #viereelle
#arte #BBC -
PURE, série courte (6 x 36min) qui traite des TOC sexuels .
Une bonne comédie dramatique adaptée d'une histoire vraie.
Bien jouée et touchante.https://www.arte.tv/fr/videos/103431-001-A/pure-1-6/
#pure #pureO #TOC #reellife #OCD #sexe #sex #penséesIntrusive #viereelle
#arte #BBC -
PURE, série courte (6 x 36min) qui traite des TOC sexuels (pensées intrusives à caractère sexuel).
Une bonne comédie dramatique adaptée d'une histoire vraie.
Bien jouée et touchante.https://www.arte.tv/fr/videos/103431-001-A/pure-1-6/
#pure #pureO #TOC #reellife #OCD #sexe #sex #penséesIntrusive #viereelle
#arte #BBC -
PURE, série courte (6 x 36min) qui traite des TOC sexuels .
Une bonne comédie dramatique adaptée d'une histoire vraie.
Bien jouée et touchante.https://www.arte.tv/fr/videos/103431-001-A/pure-1-6/
#pure #pureO #TOC #reellife #OCD #sexe #sex #penséesIntrusive #viereelle
#arte #BBC -
DATE: August 7, 2026 at 12:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Brain wiring patterns linked to harm avoidance in obsessive-compulsive disorder
Researchers have identified a specific pattern of brain wiring associated with the tendency to excessively avoid potential harm, a common trait in obsessive-compulsive disorder and other psychiatric conditions. The study, published in Neuropsychopharmacology, shows that denser microscopic connections between two distinct brain regions relate to higher levels of this avoidance behavior across different diagnostic groups. These structural brain differences offer a biological target for researchers developing future psychiatric treatments.
Obsessive-compulsive disorder involves intrusive thoughts and repetitive behaviors. Two primary dimensions often drive these symptoms. One is harm avoidance, an intense sensitivity to potential threats and an urge to prevent them. The other is incompleteness, a persistent feeling that things are imperfect or not quite right.
These traits are not exclusive to obsessive-compulsive disorder. Harm avoidance frequently occurs in anxiety disorders and post-traumatic stress disorder. Incompleteness is a hallmark symptom of obsessive-compulsive personality disorder, a distinct condition characterized by rigid perfectionism and a need for control.
Because these behavioral traits appear across various mental health conditions, researchers suspect they might share common biological roots in the brain. Previous brain imaging studies hinted at a relationship between the prefrontal cortex and the severity of these symptoms. The prefrontal cortex is the area of the brain that handles high-level cognitive functions, including risk assessment and emotional regulation.
University of Pittsburgh psychiatry researcher João Paulo Lima Santos led a team to investigate the brain architecture underlying these specific behavioral traits. Along with senior researchers Steven A. Rasmussen and Mary L. Phillips, Lima Santos aimed to replicate earlier findings in a new group of participants. The researchers also wanted to see if these brain patterns appear in people with other psychiatric diagnoses, pointing to a universal biological mechanism.
The study utilized diffusion magnetic resonance imaging, a specialized scanning technique. This technology allows researchers to map white matter in the brain. White matter consists of the insulated nerve fibers that act as communication cables, transmitting signals between different brain regions.
Through a computational process called whole-brain tractography, algorithms trace the path of water molecules as they diffuse along these nerve fibers. Because water moves more easily along the length of a fiber rather than across its boundaries, mapping this diffusion reveals the brain’s internal wiring diagram.
The research team focused on tracts connecting the prefrontal cortex to subcortical regions deep within the brain. Specifically, they looked at the thalamus, which acts as the brain’s central relay station for sensory and motor signals. They also examined connections to the striatum, a cluster of neurons involved in reward processing and habit formation.
To quantify the microscopic structure of these connections, the scientists measured fractional anisotropy. This metric indicates the density and directional alignment of white matter fibers. Higher fractional anisotropy suggests a denser, more structurally organized bundle of nerve connections.
The researchers recruited a diverse set of participants for their primary analysis. This included a small study group of 38 healthy controls and another group of 47 individuals diagnosed with obsessive-compulsive disorder. Participants completed specialized clinical questionnaires to measure their baseline levels of harm avoidance and incompleteness.
In their first statistical model, the researchers analyzed the healthy controls and the participants with obsessive-compulsive disorder. They found that higher fractional anisotropy in the connections between the dorsomedial prefrontal cortex and the thalamus related to higher levels of harm avoidance. This pattern appeared in both the left and right hemispheres of the brain.
The dorsomedial prefrontal cortex is heavily involved in evaluating situational demands and preparing responses to potential threats. A denser connection between this area and the thalamus might reflect an overactive system for perceiving danger. This heightened sensitivity could biologically drive the behavioral patterns of harm avoidance.
In the same group, the researchers also looked at the feeling of incompleteness. They observed that higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection was associated with higher incompleteness scores. The team found no statistical relationship between prefrontal-striatum connections and either symptom dimension.
The researchers looked at other secondary metrics of water diffusion in the brain, including radial diffusivity and axial diffusivity. These additional metrics yielded no statistical associations with the behavioral traits.
Next, the researchers expanded their analysis to test whether these structural associations exist outside of typical obsessive-compulsive disorder. They added a small group of 21 participants diagnosed with obsessive-compulsive personality disorder. In this expanded pool, the structural links to both harm avoidance and incompleteness remained the same.
The team then added another 20 participants who had non-obsessive-compulsive psychiatric conditions, such as panic disorder, social anxiety, and post-traumatic stress disorder. In this broader group, the association between both the left and right dorsomedial prefrontal-thalamic connections and harm avoidance persisted. The link to incompleteness was not statistically significant in this specific model.
To test the robustness of their findings, the scientists created a final, combined dataset. They merged their current participants with data from an older, original study pool containing 42 healthy controls and 44 people with obsessive-compulsive disorder. This created a much larger and more clinically diverse sample.
In this combined analysis, higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection once again tracked with higher levels of both harm avoidance and incompleteness. The connection in the right hemisphere lost its statistical association with harm avoidance in this expanded group.
Across all the different models, the connection in the left hemisphere consistently predicted the severity of harm avoidance. This persistence suggests that the left prefrontal-thalamic pathway might serve as a universal biological mechanism for threat sensitivity across different psychiatric populations. The right hemisphere connection appears more sensitive to the specific makeup or severity of the patient group.
The study design is observational and prevents researchers from determining cause and effect. It is unclear if denser white matter tracts cause heightened threat sensitivity or if a lifetime of hypervigilant behavior alters the brain’s physical structure.
The participant groups for the individual psychiatric conditions were relatively small. These small sample sizes limit the statistical power of the specific within-group analyses. Larger studies with greater variability in symptom severity are necessary to confirm these structural brain patterns.
The researchers used automated software to label the different regions of the brain. While standard in the neuroimaging field, this automated method might miss subtle anatomical differences between individual people. Future research could combine automated tools with individualized brain mapping for greater precision.
The neuroimaging protocol relied on single-shell diffusion magnetic resonance imaging. This older scanning method captures less microscopic detail than newer multi-shell techniques. More advanced imaging could provide a more nuanced picture of the specific white matter fiber segments involved in these psychiatric conditions.
While the researchers found that current psychiatric medications did not alter the results, the study did not track long-term medication use. Future longitudinal studies will need to monitor how pharmaceutical treatments might physically change these white matter connections over time.
The study, “Medial prefrontal-thalamic white matter microstructure is associated with harm avoidance in OCD: a discovery and transdiagnostic replication study,” was authored by João Paulo Lima Santos, Amelia Versace, Manan Arora, Michele A. Bertocci, Henry W. Chase, Simona Graur, Lisa Bonar, Chiara Maffei, Anastasia Yendiki, Christina L. Boisseau, Suzanne N. Haber, Steven A. Rasmussen, and Mary L. Phillips.
-------------------------------------------------
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #harmavoidance #OCD #prefrontalthalamicconnection #white matter #diffusionMRI #neuroimaging #mentalhealthresearch #transdiagnostic #dorsomedialPFC #brainwiring
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DATE: August 7, 2026 at 12:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Brain wiring patterns linked to harm avoidance in obsessive-compulsive disorder
Researchers have identified a specific pattern of brain wiring associated with the tendency to excessively avoid potential harm, a common trait in obsessive-compulsive disorder and other psychiatric conditions. The study, published in Neuropsychopharmacology, shows that denser microscopic connections between two distinct brain regions relate to higher levels of this avoidance behavior across different diagnostic groups. These structural brain differences offer a biological target for researchers developing future psychiatric treatments.
Obsessive-compulsive disorder involves intrusive thoughts and repetitive behaviors. Two primary dimensions often drive these symptoms. One is harm avoidance, an intense sensitivity to potential threats and an urge to prevent them. The other is incompleteness, a persistent feeling that things are imperfect or not quite right.
These traits are not exclusive to obsessive-compulsive disorder. Harm avoidance frequently occurs in anxiety disorders and post-traumatic stress disorder. Incompleteness is a hallmark symptom of obsessive-compulsive personality disorder, a distinct condition characterized by rigid perfectionism and a need for control.
Because these behavioral traits appear across various mental health conditions, researchers suspect they might share common biological roots in the brain. Previous brain imaging studies hinted at a relationship between the prefrontal cortex and the severity of these symptoms. The prefrontal cortex is the area of the brain that handles high-level cognitive functions, including risk assessment and emotional regulation.
University of Pittsburgh psychiatry researcher João Paulo Lima Santos led a team to investigate the brain architecture underlying these specific behavioral traits. Along with senior researchers Steven A. Rasmussen and Mary L. Phillips, Lima Santos aimed to replicate earlier findings in a new group of participants. The researchers also wanted to see if these brain patterns appear in people with other psychiatric diagnoses, pointing to a universal biological mechanism.
The study utilized diffusion magnetic resonance imaging, a specialized scanning technique. This technology allows researchers to map white matter in the brain. White matter consists of the insulated nerve fibers that act as communication cables, transmitting signals between different brain regions.
Through a computational process called whole-brain tractography, algorithms trace the path of water molecules as they diffuse along these nerve fibers. Because water moves more easily along the length of a fiber rather than across its boundaries, mapping this diffusion reveals the brain’s internal wiring diagram.
The research team focused on tracts connecting the prefrontal cortex to subcortical regions deep within the brain. Specifically, they looked at the thalamus, which acts as the brain’s central relay station for sensory and motor signals. They also examined connections to the striatum, a cluster of neurons involved in reward processing and habit formation.
To quantify the microscopic structure of these connections, the scientists measured fractional anisotropy. This metric indicates the density and directional alignment of white matter fibers. Higher fractional anisotropy suggests a denser, more structurally organized bundle of nerve connections.
The researchers recruited a diverse set of participants for their primary analysis. This included a small study group of 38 healthy controls and another group of 47 individuals diagnosed with obsessive-compulsive disorder. Participants completed specialized clinical questionnaires to measure their baseline levels of harm avoidance and incompleteness.
In their first statistical model, the researchers analyzed the healthy controls and the participants with obsessive-compulsive disorder. They found that higher fractional anisotropy in the connections between the dorsomedial prefrontal cortex and the thalamus related to higher levels of harm avoidance. This pattern appeared in both the left and right hemispheres of the brain.
The dorsomedial prefrontal cortex is heavily involved in evaluating situational demands and preparing responses to potential threats. A denser connection between this area and the thalamus might reflect an overactive system for perceiving danger. This heightened sensitivity could biologically drive the behavioral patterns of harm avoidance.
In the same group, the researchers also looked at the feeling of incompleteness. They observed that higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection was associated with higher incompleteness scores. The team found no statistical relationship between prefrontal-striatum connections and either symptom dimension.
The researchers looked at other secondary metrics of water diffusion in the brain, including radial diffusivity and axial diffusivity. These additional metrics yielded no statistical associations with the behavioral traits.
Next, the researchers expanded their analysis to test whether these structural associations exist outside of typical obsessive-compulsive disorder. They added a small group of 21 participants diagnosed with obsessive-compulsive personality disorder. In this expanded pool, the structural links to both harm avoidance and incompleteness remained the same.
The team then added another 20 participants who had non-obsessive-compulsive psychiatric conditions, such as panic disorder, social anxiety, and post-traumatic stress disorder. In this broader group, the association between both the left and right dorsomedial prefrontal-thalamic connections and harm avoidance persisted. The link to incompleteness was not statistically significant in this specific model.
To test the robustness of their findings, the scientists created a final, combined dataset. They merged their current participants with data from an older, original study pool containing 42 healthy controls and 44 people with obsessive-compulsive disorder. This created a much larger and more clinically diverse sample.
In this combined analysis, higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection once again tracked with higher levels of both harm avoidance and incompleteness. The connection in the right hemisphere lost its statistical association with harm avoidance in this expanded group.
Across all the different models, the connection in the left hemisphere consistently predicted the severity of harm avoidance. This persistence suggests that the left prefrontal-thalamic pathway might serve as a universal biological mechanism for threat sensitivity across different psychiatric populations. The right hemisphere connection appears more sensitive to the specific makeup or severity of the patient group.
The study design is observational and prevents researchers from determining cause and effect. It is unclear if denser white matter tracts cause heightened threat sensitivity or if a lifetime of hypervigilant behavior alters the brain’s physical structure.
The participant groups for the individual psychiatric conditions were relatively small. These small sample sizes limit the statistical power of the specific within-group analyses. Larger studies with greater variability in symptom severity are necessary to confirm these structural brain patterns.
The researchers used automated software to label the different regions of the brain. While standard in the neuroimaging field, this automated method might miss subtle anatomical differences between individual people. Future research could combine automated tools with individualized brain mapping for greater precision.
The neuroimaging protocol relied on single-shell diffusion magnetic resonance imaging. This older scanning method captures less microscopic detail than newer multi-shell techniques. More advanced imaging could provide a more nuanced picture of the specific white matter fiber segments involved in these psychiatric conditions.
While the researchers found that current psychiatric medications did not alter the results, the study did not track long-term medication use. Future longitudinal studies will need to monitor how pharmaceutical treatments might physically change these white matter connections over time.
The study, “Medial prefrontal-thalamic white matter microstructure is associated with harm avoidance in OCD: a discovery and transdiagnostic replication study,” was authored by João Paulo Lima Santos, Amelia Versace, Manan Arora, Michele A. Bertocci, Henry W. Chase, Simona Graur, Lisa Bonar, Chiara Maffei, Anastasia Yendiki, Christina L. Boisseau, Suzanne N. Haber, Steven A. Rasmussen, and Mary L. Phillips.
-------------------------------------------------
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #harmavoidance #OCD #prefrontalthalamicconnection #white matter #diffusionMRI #neuroimaging #mentalhealthresearch #transdiagnostic #dorsomedialPFC #brainwiring
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DATE: August 7, 2026 at 12:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Brain wiring patterns linked to harm avoidance in obsessive-compulsive disorder
Researchers have identified a specific pattern of brain wiring associated with the tendency to excessively avoid potential harm, a common trait in obsessive-compulsive disorder and other psychiatric conditions. The study, published in Neuropsychopharmacology, shows that denser microscopic connections between two distinct brain regions relate to higher levels of this avoidance behavior across different diagnostic groups. These structural brain differences offer a biological target for researchers developing future psychiatric treatments.
Obsessive-compulsive disorder involves intrusive thoughts and repetitive behaviors. Two primary dimensions often drive these symptoms. One is harm avoidance, an intense sensitivity to potential threats and an urge to prevent them. The other is incompleteness, a persistent feeling that things are imperfect or not quite right.
These traits are not exclusive to obsessive-compulsive disorder. Harm avoidance frequently occurs in anxiety disorders and post-traumatic stress disorder. Incompleteness is a hallmark symptom of obsessive-compulsive personality disorder, a distinct condition characterized by rigid perfectionism and a need for control.
Because these behavioral traits appear across various mental health conditions, researchers suspect they might share common biological roots in the brain. Previous brain imaging studies hinted at a relationship between the prefrontal cortex and the severity of these symptoms. The prefrontal cortex is the area of the brain that handles high-level cognitive functions, including risk assessment and emotional regulation.
University of Pittsburgh psychiatry researcher João Paulo Lima Santos led a team to investigate the brain architecture underlying these specific behavioral traits. Along with senior researchers Steven A. Rasmussen and Mary L. Phillips, Lima Santos aimed to replicate earlier findings in a new group of participants. The researchers also wanted to see if these brain patterns appear in people with other psychiatric diagnoses, pointing to a universal biological mechanism.
The study utilized diffusion magnetic resonance imaging, a specialized scanning technique. This technology allows researchers to map white matter in the brain. White matter consists of the insulated nerve fibers that act as communication cables, transmitting signals between different brain regions.
Through a computational process called whole-brain tractography, algorithms trace the path of water molecules as they diffuse along these nerve fibers. Because water moves more easily along the length of a fiber rather than across its boundaries, mapping this diffusion reveals the brain’s internal wiring diagram.
The research team focused on tracts connecting the prefrontal cortex to subcortical regions deep within the brain. Specifically, they looked at the thalamus, which acts as the brain’s central relay station for sensory and motor signals. They also examined connections to the striatum, a cluster of neurons involved in reward processing and habit formation.
To quantify the microscopic structure of these connections, the scientists measured fractional anisotropy. This metric indicates the density and directional alignment of white matter fibers. Higher fractional anisotropy suggests a denser, more structurally organized bundle of nerve connections.
The researchers recruited a diverse set of participants for their primary analysis. This included a small study group of 38 healthy controls and another group of 47 individuals diagnosed with obsessive-compulsive disorder. Participants completed specialized clinical questionnaires to measure their baseline levels of harm avoidance and incompleteness.
In their first statistical model, the researchers analyzed the healthy controls and the participants with obsessive-compulsive disorder. They found that higher fractional anisotropy in the connections between the dorsomedial prefrontal cortex and the thalamus related to higher levels of harm avoidance. This pattern appeared in both the left and right hemispheres of the brain.
The dorsomedial prefrontal cortex is heavily involved in evaluating situational demands and preparing responses to potential threats. A denser connection between this area and the thalamus might reflect an overactive system for perceiving danger. This heightened sensitivity could biologically drive the behavioral patterns of harm avoidance.
In the same group, the researchers also looked at the feeling of incompleteness. They observed that higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection was associated with higher incompleteness scores. The team found no statistical relationship between prefrontal-striatum connections and either symptom dimension.
The researchers looked at other secondary metrics of water diffusion in the brain, including radial diffusivity and axial diffusivity. These additional metrics yielded no statistical associations with the behavioral traits.
Next, the researchers expanded their analysis to test whether these structural associations exist outside of typical obsessive-compulsive disorder. They added a small group of 21 participants diagnosed with obsessive-compulsive personality disorder. In this expanded pool, the structural links to both harm avoidance and incompleteness remained the same.
The team then added another 20 participants who had non-obsessive-compulsive psychiatric conditions, such as panic disorder, social anxiety, and post-traumatic stress disorder. In this broader group, the association between both the left and right dorsomedial prefrontal-thalamic connections and harm avoidance persisted. The link to incompleteness was not statistically significant in this specific model.
To test the robustness of their findings, the scientists created a final, combined dataset. They merged their current participants with data from an older, original study pool containing 42 healthy controls and 44 people with obsessive-compulsive disorder. This created a much larger and more clinically diverse sample.
In this combined analysis, higher fractional anisotropy in the left dorsomedial prefrontal-thalamic connection once again tracked with higher levels of both harm avoidance and incompleteness. The connection in the right hemisphere lost its statistical association with harm avoidance in this expanded group.
Across all the different models, the connection in the left hemisphere consistently predicted the severity of harm avoidance. This persistence suggests that the left prefrontal-thalamic pathway might serve as a universal biological mechanism for threat sensitivity across different psychiatric populations. The right hemisphere connection appears more sensitive to the specific makeup or severity of the patient group.
The study design is observational and prevents researchers from determining cause and effect. It is unclear if denser white matter tracts cause heightened threat sensitivity or if a lifetime of hypervigilant behavior alters the brain’s physical structure.
The participant groups for the individual psychiatric conditions were relatively small. These small sample sizes limit the statistical power of the specific within-group analyses. Larger studies with greater variability in symptom severity are necessary to confirm these structural brain patterns.
The researchers used automated software to label the different regions of the brain. While standard in the neuroimaging field, this automated method might miss subtle anatomical differences between individual people. Future research could combine automated tools with individualized brain mapping for greater precision.
The neuroimaging protocol relied on single-shell diffusion magnetic resonance imaging. This older scanning method captures less microscopic detail than newer multi-shell techniques. More advanced imaging could provide a more nuanced picture of the specific white matter fiber segments involved in these psychiatric conditions.
While the researchers found that current psychiatric medications did not alter the results, the study did not track long-term medication use. Future longitudinal studies will need to monitor how pharmaceutical treatments might physically change these white matter connections over time.
The study, “Medial prefrontal-thalamic white matter microstructure is associated with harm avoidance in OCD: a discovery and transdiagnostic replication study,” was authored by João Paulo Lima Santos, Amelia Versace, Manan Arora, Michele A. Bertocci, Henry W. Chase, Simona Graur, Lisa Bonar, Chiara Maffei, Anastasia Yendiki, Christina L. Boisseau, Suzanne N. Haber, Steven A. Rasmussen, and Mary L. Phillips.
-------------------------------------------------
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #harmavoidance #OCD #prefrontalthalamicconnection #white matter #diffusionMRI #neuroimaging #mentalhealthresearch #transdiagnostic #dorsomedialPFC #brainwiring
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Listening to Kimberley discuss how AI chatbots reenforce the cycle of reassurance seeking by #anxiety #ocd sufferers (and can therefore make it worse) on a new episode of Your Anxiety Toolkit #podcast #ocd #anxiety
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780445854
-
Listening to Kimberley discuss how AI chatbots reenforce the cycle of reassurance seeking by #anxiety #ocd sufferers (and can therefore make it worse) on a new episode of Your Anxiety Toolkit #podcast #ocd #anxiety
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780445854
-
Listening to Kimberley discuss how AI chatbots reenforce the cycle of reassurance seeking by #anxiety #ocd sufferers (and can therefore make it worse) on a new episode of Your Anxiety Toolkit #podcast #ocd #anxiety
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780445854
-
Listening to Kimberley discuss how AI chatbots reenforce the cycle of reassurance seeking by #anxiety #ocd sufferers (and can therefore make it worse) on a new episode of Your Anxiety Toolkit #podcast #ocd #anxiety
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780445854
-
Listening to Kimberley discuss how AI chatbots reenforce the cycle of reassurance seeking by #anxiety #ocd sufferers (and can therefore make it worse) on a new episode of Your Anxiety Toolkit #podcast #ocd #anxiety
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780445854
-
Listening to Kimberley interview Rebecca DeLeon about how adding DBT skills to ERP can help #ocd sufferers tolerate overwhemling emotions on a new Your Anxiety Toolkit #podcast. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780043004
-
Listening to Kimberley interview Rebecca DeLeon about how adding DBT skills to ERP can help #ocd sufferers tolerate overwhemling emotions on a new Your Anxiety Toolkit #podcast. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780043004
-
Listening to Kimberley interview Rebecca DeLeon about how adding DBT skills to ERP can help #ocd sufferers tolerate overwhemling emotions on a new Your Anxiety Toolkit #podcast. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780043004
-
Listening to Kimberley interview Rebecca DeLeon about how adding DBT skills to ERP can help #ocd sufferers tolerate overwhemling emotions on a new Your Anxiety Toolkit #podcast. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780043004
-
Listening to Kimberley interview Rebecca DeLeon about how adding DBT skills to ERP can help #ocd sufferers tolerate overwhemling emotions on a new Your Anxiety Toolkit #podcast. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000780043004
-
Wrapping up today's #podcast listens with a new Your Anxiety Toolkit in which Kimberley shares why overthinking is a thinking problem and what to do about it. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000778884613
-
Wrapping up today's #podcast listens with a new Your Anxiety Toolkit in which Kimberley shares why overthinking is a thinking problem and what to do about it. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000778884613
-
Wrapping up today's #podcast listens with a new Your Anxiety Toolkit in which Kimberley shares why overthinking is a thinking problem and what to do about it. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000778884613
-
Wrapping up today's #podcast listens with a new Your Anxiety Toolkit in which Kimberley shares why overthinking is a thinking problem and what to do about it. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000778884613
-
Wrapping up today's #podcast listens with a new Your Anxiety Toolkit in which Kimberley shares why overthinking is a thinking problem and what to do about it. #anxiety #MentalHealth #ocd
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000778884613
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I hate when my anxiety meds don't work, because then I'm anxious about the thing I was anxious about but also now I'm anxious about the idea that my meds might never work again.
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I hate when my anxiety meds don't work, because then I'm anxious about the thing I was anxious about but also now I'm anxious about the idea that my meds might never work again.
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I hate when my anxiety meds don't work, because then I'm anxious about the thing I was anxious about but also now I'm anxious about the idea that my meds might never work again.
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I hate when my anxiety meds don't work, because then I'm anxious about the thing I was anxious about but also now I'm anxious about the idea that my meds might never work again.
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I hate when my anxiety meds don't work, because then I'm anxious about the thing I was anxious about but also now I'm anxious about the idea that my meds might never work again.
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CW: Mental health, personal win, longish
I made a big decision about my health tonight, not letting my psychiatrist damage my liver. Sound weird? Let me explain.
So my psychiatrist that I started seeing recently agreed to start getting me off Luvox. I got put on it when I was diagnosed with moderate OCD in May, and when they upped my dose in June I got MUCH worse. So I’m finally back down to my original dose and that makes me feel better, and in a little bit I should be coming off of it.
But here’s the thing. my new psychiatrist is very knowledgeable about medication and that’s why I picked her. but she wants me to try a mood stabilizer. she says her patients often have great success with a pairing of SSRI and mood stabilizer. But this is definitely off label and not super common from what I see.
So she prescribed me depakote. Depakote is typically given to people with seizures or bipolar disorder. which I do not have either. But the big thing for me is that there’s a major warning of possible liver failure from the drug. she said it’s only for higher doses, but I don’t trust that. I am finally recovering my liver health after finding out last year I had fatty liver from my diabetes, and all of that is finally under control. My sugar is almost back to a typical range, and my liver numbers are also back to normal.
So I’ve made a big decision. I’m just gonna stop taking the depakote. I took it for two days. The first dose gave me brain fog all evening. I’m meeting with her in two weeks and I’m just gonna tell her I’m not comfortable with it. I don’t need to just take everything I’m prescribed. it’s my body and my health.
Instead of over medicating myself, I’m trying to get a session set up with an OCD trained therapist to help me manage my issues. Exposure and response prevention is a proven strategy for all types of OCD. And between that and my normal CBT for generalized anxiety, I think I’ll put myself in a much better position!
I’m so proud of myself for making this decision. it’s a big step for me and I’m hopeful for the future again.
#MentalHealth #OCD #Anxiety -
CW: Mental health, personal win, longish
I made a big decision about my health tonight, not letting my psychiatrist damage my liver. Sound weird? Let me explain.
So my psychiatrist that I started seeing recently agreed to start getting me off Luvox. I got put on it when I was diagnosed with moderate OCD in May, and when they upped my dose in June I got MUCH worse. So I’m finally back down to my original dose and that makes me feel better, and in a little bit I should be coming off of it.
But here’s the thing. my new psychiatrist is very knowledgeable about medication and that’s why I picked her. but she wants me to try a mood stabilizer. she says her patients often have great success with a pairing of SSRI and mood stabilizer. But this is definitely off label and not super common from what I see.
So she prescribed me depakote. Depakote is typically given to people with seizures or bipolar disorder. which I do not have either. But the big thing for me is that there’s a major warning of possible liver failure from the drug. she said it’s only for higher doses, but I don’t trust that. I am finally recovering my liver health after finding out last year I had fatty liver from my diabetes, and all of that is finally under control. My sugar is almost back to a typical range, and my liver numbers are also back to normal.
So I’ve made a big decision. I’m just gonna stop taking the depakote. I took it for two days. The first dose gave me brain fog all evening. I’m meeting with her in two weeks and I’m just gonna tell her I’m not comfortable with it. I don’t need to just take everything I’m prescribed. it’s my body and my health.
Instead of over medicating myself, I’m trying to get a session set up with an OCD trained therapist to help me manage my issues. Exposure and response prevention is a proven strategy for all types of OCD. And between that and my normal CBT for generalized anxiety, I think I’ll put myself in a much better position!
I’m so proud of myself for making this decision. it’s a big step for me and I’m hopeful for the future again.
#MentalHealth #OCD #Anxiety -
@Standard_Phil exactly! I should have attached multiple warnings. #diy trigger #ocd trigger #travelanxiety
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@Standard_Phil exactly! I should have attached multiple warnings. #diy trigger #ocd trigger #travelanxiety
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@Standard_Phil exactly! I should have attached multiple warnings. #diy trigger #ocd trigger #travelanxiety
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@Standard_Phil exactly! I should have attached multiple warnings. #diy trigger #ocd trigger #travelanxiety
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@Standard_Phil exactly! I should have attached multiple warnings. #diy trigger #ocd trigger #travelanxiety
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By the way: Backrooms movie was good. Highly recommend you watch the YouTube videos first-so you get the idea of it all.
As an OCD person-I also see the Backrooms idea as a metaphor for getting “stuck” in thought loops and mental frameworks that are unhealthy.
#DayInTheLife #Backrooms #backrooms_2026_film
#MentalHealth
#OCD -
By the way: Backrooms movie was good. Highly recommend you watch the YouTube videos first-so you get the idea of it all.
As an OCD person-I also see the Backrooms idea as a metaphor for getting “stuck” in thought loops and mental frameworks that are unhealthy.
#DayInTheLife #Backrooms #backrooms_2026_film
#MentalHealth
#OCD -
By the way: Backrooms movie was good. Highly recommend you watch the YouTube videos first-so you get the idea of it all.
As an OCD person-I also see the Backrooms idea as a metaphor for getting “stuck” in thought loops and mental frameworks that are unhealthy.
#DayInTheLife #Backrooms #backrooms_2026_film
#MentalHealth
#OCD -
By the way: Backrooms movie was good. Highly recommend you watch the YouTube videos first-so you get the idea of it all.
As an OCD person-I also see the Backrooms idea as a metaphor for getting “stuck” in thought loops and mental frameworks that are unhealthy.
#DayInTheLife #Backrooms #backrooms_2026_film
#MentalHealth
#OCD -
By the way: Backrooms movie was good. Highly recommend you watch the YouTube videos first-so you get the idea of it all.
As an OCD person-I also see the Backrooms idea as a metaphor for getting “stuck” in thought loops and mental frameworks that are unhealthy.
#DayInTheLife #Backrooms #backrooms_2026_film
#MentalHealth
#OCD -
Listening to a bonus episode of Your Anxiety Toolkit in which Kimberley discusses the OCD signs most people miss. #ocd #anxiety #mentalHealth #podcast
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000777248145
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Listening to a bonus episode of Your Anxiety Toolkit in which Kimberley discusses the OCD signs most people miss. #ocd #anxiety #mentalHealth #podcast
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000777248145
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Listening to a bonus episode of Your Anxiety Toolkit in which Kimberley discusses the OCD signs most people miss. #ocd #anxiety #mentalHealth #podcast
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000777248145
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Listening to a bonus episode of Your Anxiety Toolkit in which Kimberley discusses the OCD signs most people miss. #ocd #anxiety #mentalHealth #podcast
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000777248145
-
Listening to a bonus episode of Your Anxiety Toolkit in which Kimberley discusses the OCD signs most people miss. #ocd #anxiety #mentalHealth #podcast
https://podcasts.apple.com/us/podcast/your-anxiety-toolkit/id1098792502?i=1000777248145
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Former top UK cop killed dad-of-two in horror crash after 'blackout' at wheel
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Former top UK cop killed dad-of-two in horror crash after 'blackout' at wheel
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Former top UK cop killed dad-of-two in horror crash after 'blackout' at wheel
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Former top UK cop killed dad-of-two in horror crash after 'blackout' at wheel
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Former top UK cop killed dad-of-two in horror crash after 'blackout' at wheel
