#scrnaseq — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #scrnaseq, aggregated by home.social.
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The main #ECCB2026 conference may be over, but today lots of great people are meeting to discuss single-cell standards and collaborations:
Single-cell and spatial data FAIRification, community standards and training
organised by @fbastian @SIB & @elixir_europe
eccb2026.org/communities-day#single-cell-and-spatial-data-fairification
#scRNAseq #SingleCell #FAIRdata #bioinformatics #OpenData #GenevaLovesData -
2D embeddings for high-dimensional data, the battle rages on
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012403
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"By using time-resolved analyses of scRNA-seq data, we determined the potential transitional trajectories of tumor cells and identified the metastasis-initiating subpopulations"
https://link.springer.com/article/10.1007/s11684-024-1081-7
Reading right now. The identification of cells that initiate #metastasis are of interest, although n=2 paired primary and #BoneMarrow samples may be a bit limited.
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I made a short video of the strange things UMAP and t-SNE can do to your data. The algorithms are shown mostly working as intended, yet with some surprising consequences.
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Come and work with us - job opening at the Molenaar research group in the Princess Máxima Center for pediatric oncology, looking for a #bioinformatician / #DataScientist.
Together with my colleagues and me you will research #neuroblastoma, with a focus on #tumour #microenvironment and the #immune compartment using a range of #sequencing data and other high-throughput data.
#CancerResearch #scRNAseq
#FediJobs #JobOfferFor further information, see the vacancy below:
https://werkenbijprinsesmaximacentrum.nl/en/vacancy/bioinformatics-research-scientist/ -
"Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma"
Nice new work based on #scRNAseq from our Drost group colleagues at the #PrincessMaximaCenter. a.o., a potential role of #NECTIN3 and #TIGIT in #tumour-induced T cell dysfunction.
https://www.nature.com/articles/s41467-023-38886-8 -
That session was concluded by Caroline Hochheuser showing our own #scRNAseq work, comparing primary #tumour to bone marrow #metastasis from the same patients. 🤩
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Yesterday, in the afternoon plenty of #scRNAseq work, a.o. Céline Delloye-Bourgeois showing her group's latest work on #neuroblastoma development and #metastatic progression. Including some of our own scRNA-seq data. Very cool.
Furthermore, more #SingleCell, also spatial, sequencing on #tumour heterogeneity and early stages. And work on cells that persist during/after #therapy, dubbed persister cells.