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#metastasis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #metastasis, aggregated by home.social.

  1. Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

    Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to…
    #NewsBeep #News #Health #AU #Australia #Bases #BreastCancer #Cancer #carcinoma #Cell #cellbiology #Gene #GeneExpression #Genes #Genomic #medicine #Metastasis #Proliferation #protein #research #StemCells #Therapeutics #therapy
    newsbeep.com/au/602035/

  2. Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

    Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to…
    #NewsBeep #News #Health #AU #Australia #Bases #BreastCancer #Cancer #carcinoma #Cell #cellbiology #Gene #GeneExpression #Genes #Genomic #medicine #Metastasis #Proliferation #protein #research #StemCells #Therapeutics #therapy
    newsbeep.com/au/602035/

  3. 𝐀 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐜𝐚𝐥 𝐯𝐢𝐞𝐰 𝐨𝐧 #𝐦𝐞𝐭𝐚𝐬𝐭𝐚𝐬𝐢𝐬 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐫𝐨𝐥𝐞 𝐨𝐟 𝐭𝐮𝐦𝐨𝐫 𝐜𝐞𝐥𝐥 𝐯𝐢𝐬𝐜𝐨𝐬𝐢𝐭𝐲

    #Cancer cells can detach from the original tumor and travel through the bloodstream to form metastases in the body. An international #research team investigated how the mechanical properties of #tumor cells influence their metastatic pathway. The key finding: viscosity – rather than elasticity – determines how tumor cells invade surrounding tissue.

    👉 mpzpm.mpg.de/news/news-details
    📸 V. Gensbittel, J. Goetz
     
    #science #biophysics

  4. Researchers at the University of Geneva (UNIGE) have developed an artificial intelligence algorithm capable of predicting the risk of #cancer #metastasis and recurrence with high reliability.
    #AI #ArtificialIntelligence #Oncology #Genetics #sflorg
    sflorg.com/2026/01/ongy0122260

  5. #MitochondrialDynamics are important regulators of various cancer cell phenotypes. This Essay explores the role of mitochondrial dynamic regulators in #tumor growth & #metastasis, discussing how they can be targeted to develop novel intervention strategies
    @PLOSBiology plos.io/4o4KtOo

  6. Cells migrate as part of their normal function (patrolling #immune cells...), but also when malignant (think of #metastasis). Their velocity is an important parameter but difficult to quantify. Simo Kitanovski et al have developed a new quantitative Bayesian approach for experimental data analysis, #cellmig, that hopefully will set a new standard for reproducibility.
    biorxiv.org/content/10.1101/20
    Free open source software:
    bioconductor.org/packages/cell

  7. Mechanical confinement can deform #cancer cell nuclei and trigger transition to an invasive phenotype. Study on melanoma in animal model and human samples. #Metastasis nature.com/articles/s41586-025

  8. The first fully resolved crystal structure of human fascin1 is presented, fully modeling both molecules in the asymmetric unit and offering new insights into its conformational dynamics and structural plasticity #Cancer #Metastasis doi.org/10.1107/S2053230X25005

  9. Final #MathOnco keynote at #SMB2025 @smbmathbiology.bsky.social with Mohit K. Jolly taling about Epithelial to Messenchymal Plasticity (EMP). Great talk and of great importance not just for #metastasis (the context in which it is usually studied) but also #treatmentResistance

  10. #Neutrophils are very abundant and generally helpful #immune cells. However, in tumors they can misfire and form large clumps that block blood vessels. This blockage causes necrosis & metabolic adaptation of #tumor and #metastasis.
    nature.com/articles/s41586-025

  11. Substances that slow down migrating cancer cells could be anti-metastatic drug candidates. In this preprint we describe the first computational model for quantitative analysis of cell migration assays for substance screening. #bayes
    #cellmigration #metastasis
    biorxiv.org/content/10.1101/20

  12. Chronic stress increases #metastasis. Paper describes one mechanism: stress-related glucocorticoids make #neutrophils produce #NETs and thus metastasis-friendly milieu. cell.com/cancer-cell/fulltext/

  13. "By using time-resolved analyses of scRNA-seq data, we determined the potential transitional trajectories of tumor cells and identified the metastasis-initiating subpopulations"

    link.springer.com/article/10.1

    Reading right now. The identification of cells that initiate #metastasis are of interest, although n=2 paired primary and #BoneMarrow samples may be a bit limited.

    #scRNAseq #tumour #Neuroblastoma #pseudotime

  14. “EVALUACIÓN DE LA ACTIVIDAD
    QUIMIOTÁCTICA Y EL POTENCIAL
    INVASIVO DE UNA LÍNEA CELULAR
    DE CÁNCER DE MAMA EN UN
    MODELO DE TEJIDO
    DESCELULARIZADO”
    repositorio.upch.edu.pe/handle
    #metastasis
    #thesis #spanish

  15. The K+ channel KCNK1 is differentially expressed in many #tumors, but why? Study shows that KCNK1 overexpression in #BreastCancer promotes proliferation, invasion & #metastasis by increasing #glycolysis & activating #LactateDehydrogenase. #PLOSBiology plos.io/3VTNdCr

  16. Mechanisms of metastasis.

    'Together, our data show that glucocorticoids released during chronic stress cause NET formation and establish a metastasis-promoting microenvironment. Therefore, NETs could be targets for preventing metastatic recurrence in cancer patients, many of whom will experience chronic stress due to their disease.'
    #Cancer #Neutrophils #Metastasis #Immunology

    cell.com/cancer-cell/fulltext/?