#computationalbiology — Public Fediverse posts

A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
#Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
https://www.sflorg.com/2026/05/ns05142601.html

A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
#Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
https://www.sflorg.com/2026/05/ns05142601.html

A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
#Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
https://www.sflorg.com/2026/05/ns05142601.html

A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
#Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
https://www.sflorg.com/2026/05/ns05142601.html

A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
#Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
https://www.sflorg.com/2026/05/ns05142601.html

I did a full walkthrough from creating your first experiment in bioAF to running an nf-core pipeline and getting QC results. Check out the full process here!

https://bioaf.co/blog/getting-started-with-projects-experiments-and-pipelines/

#biology #biotech #computationalbiology

⚛️ What if randomness inside cells isn’t noise — but biology’s hidden operating system?

🔗 Hybrid Physics-Informed and Bayesian Modeling of Single-Nanoparticle–Cell Adhesion Kinetics under Cytoskeletal Perturbation. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0077

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Nanomedicine #PhysicsInformedAI #BayesianModeling #Biophysics #CellBiology #ComputationalBiology #BiomedicalEngineering #AI

⚛️ What if randomness inside cells isn’t noise — but biology’s hidden operating system?

🔗 Hybrid Physics-Informed and Bayesian Modeling of Single-Nanoparticle–Cell Adhesion Kinetics under Cytoskeletal Perturbation. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0077

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Nanomedicine #PhysicsInformedAI #BayesianModeling #Biophysics #CellBiology #ComputationalBiology #BiomedicalEngineering #AI

⚛️ What if randomness inside cells isn’t noise — but biology’s hidden operating system?

🔗 Hybrid Physics-Informed and Bayesian Modeling of Single-Nanoparticle–Cell Adhesion Kinetics under Cytoskeletal Perturbation. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0077

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Nanomedicine #PhysicsInformedAI #BayesianModeling #Biophysics #CellBiology #ComputationalBiology #BiomedicalEngineering #AI

⚛️ What if randomness inside cells isn’t noise — but biology’s hidden operating system?

🔗 Hybrid Physics-Informed and Bayesian Modeling of Single-Nanoparticle–Cell Adhesion Kinetics under Cytoskeletal Perturbation. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0077

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Nanomedicine #PhysicsInformedAI #BayesianModeling #Biophysics #CellBiology #ComputationalBiology #BiomedicalEngineering #AI

⚛️ What if randomness inside cells isn’t noise — but biology’s hidden operating system?

🔗 Hybrid Physics-Informed and Bayesian Modeling of Single-Nanoparticle–Cell Adhesion Kinetics under Cytoskeletal Perturbation. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0077

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Nanomedicine #PhysicsInformedAI #BayesianModeling #Biophysics #CellBiology #ComputationalBiology #BiomedicalEngineering #AI

A personalized therapeutic DNA vaccine engineered to target unique neoantigens on a patient's tumor, stimulating the immune system to recognize and eliminate aggressive glioblastoma cells.
#Oncology #Immunology #MolecularBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/05/ongy05122601.html

A personalized therapeutic DNA vaccine engineered to target unique neoantigens on a patient's tumor, stimulating the immune system to recognize and eliminate aggressive glioblastoma cells.
#Oncology #Immunology #MolecularBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/05/ongy05122601.html

A personalized therapeutic DNA vaccine engineered to target unique neoantigens on a patient's tumor, stimulating the immune system to recognize and eliminate aggressive glioblastoma cells.
#Oncology #Immunology #MolecularBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/05/ongy05122601.html

A personalized therapeutic DNA vaccine engineered to target unique neoantigens on a patient's tumor, stimulating the immune system to recognize and eliminate aggressive glioblastoma cells.
#Oncology #Immunology #MolecularBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/05/ongy05122601.html

A personalized therapeutic DNA vaccine engineered to target unique neoantigens on a patient's tumor, stimulating the immune system to recognize and eliminate aggressive glioblastoma cells.
#Oncology #Immunology #MolecularBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/05/ongy05122601.html

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

Postdoctoral Research Scientist
Korem Lab at Columbia University

See the full job description on jobRxiv: https://jobrxiv.org/job/korem-lab-at-columbia-university-27778-postdoctoral-research-scientist-4/

#computationalbiology #machinelearning #microbiome #ScienceJobs #hiring #research
https://jobrxiv.org/job/korem-lab-at-columbia-university-27778-postdoctoral-research-scientist-4/?fsp_sid=11969

🧬 Could a single metric decode how genes are regulated across cells?

🔗 Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0044

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#GeneRegulation #Genomics #MultiOmics #SystemsBiology #Bioinformatics #ComputationalBiology #MolecularBiology #RNA #GeneExpression #Epigenetics #Transcriptomics

🧬 Could a single metric decode how genes are regulated across cells?

🔗 Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0044

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#GeneRegulation #Genomics #MultiOmics #SystemsBiology #Bioinformatics #ComputationalBiology #MolecularBiology #RNA #GeneExpression #Epigenetics #Transcriptomics

🧬 Could a single metric decode how genes are regulated across cells?

🔗 Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0044

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#GeneRegulation #Genomics #MultiOmics #SystemsBiology #Bioinformatics #ComputationalBiology #MolecularBiology #RNA #GeneExpression #Epigenetics #Transcriptomics

🧬 Could a single metric decode how genes are regulated across cells?

🔗 Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0044

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#GeneRegulation #Genomics #MultiOmics #SystemsBiology #Bioinformatics #ComputationalBiology #MolecularBiology #RNA #GeneExpression #Epigenetics #Transcriptomics

🧬 Could a single metric decode how genes are regulated across cells?

🔗 Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0044

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#GeneRegulation #Genomics #MultiOmics #SystemsBiology #Bioinformatics #ComputationalBiology #MolecularBiology #RNA #GeneExpression #Epigenetics #Transcriptomics

🧩 Could RNA and proteins share the same “shape language” for binding drugs?

🔗 Eigenvalue Ratios Reveal Shared Binding Pocket Shapes in RNA and Protein Structures. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0022

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #StructuralBiology #ComputationalBiology #RNAResearch #ProteinScience #Bioinformatics #MolecularModeling #Genomics #Proteomics #Cheminformatics #LigandBinding

Hey, gonna try my luck here with something technical:

Anyone has or knows of software or have public code to randomly select SNPs from a population or vcf file based on properties which as MAF, distance to TSS of nearest genes?

I can write something, but I'm hoping to save time here and can't find anything. I need it to do an enrichment analysis where I test real hits from the SNPs vs hits from the random ones.

#genomics #bioinformatics #gwas #academia #science #computationalbiology

Biologists MUST learn AI now! Drug discovery accelerating, genomics exploding with massive datasets 🧬💻
Bioinformatics + AI skills = scientists in HIGH demand. Don't get left behind! 🚀
Join BioResire WhatsApp for AI-Bio training 👇 https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#AIBiology #Bioinformatics #BiotechAI #Genomics #DrugDiscovery #BioinformaticsTraining #LifeScienceAI #AIinBiology #BiotechCareers #BioinformaticsJobs #ResearchAI #GenomicsData #ComputationalBiology #BiotechFuture #LifeSciences

Will AI replace bio jobs? No—scientists adapting to AI + bioinformatics thrive! 🚀 Data analysis, computational biology: new careers emerge.
Learn AI + Bioinformatics with BioResire.
Join: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#AIBioinformatics #BioResire #AIReplaceJobs #BioinformaticsAI #ComputationalBiology #AIBioJobs #LifeSciencesAI #BioResireSkills #IndiaBioinformatics #AIinBiology #BioDataAnalysis #FutureBioJobs #LearnAI #BioinformaticsTraining #WhatsAppBio #AIBioFuture #BioScientistsAI #RapidBiology

Will AI replace bio jobs? No—scientists adapting to AI + bioinformatics thrive! 🚀 Data analysis, computational biology: new careers emerge.
Learn AI + Bioinformatics with BioResire.
Join: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#AIBioinformatics #BioResire #AIReplaceJobs #BioinformaticsAI #ComputationalBiology #AIBioJobs #LifeSciencesAI #BioResireSkills #IndiaBioinformatics #AIinBiology #BioDataAnalysis #FutureBioJobs #LearnAI #BioinformaticsTraining #WhatsAppBio #AIBioFuture #BioScientistsAI #RapidBiology

The sheer scale of what synthetic biology aims to achieve can often feel indistinguishable from science fiction. We are actively learning to speak the fundamental language of life, not merely to read its ancient history, but to actively write its future.
#SyntheticBiology #MolecularBiology #ComputationalBiology #Genetics #ArtificialIntelligence #sflorg
https://www.sflorg.com/2026/04/wi04042601.html

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

🧬 Can AI truly decode gene expression, or is it being misled by too much data?

🔗 Artificial Intelligence in Bulk RNA-Seq: Challenges and Potential Solutions. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0039

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ArtificialIntelligence #MachineLearning #Bioinformatics #Genomics #RNAseq #ComputationalBiology #SystemsBiology #AI #PrecisionMedicine #BigData #AIinHealthcare

⚛️ Can we design drugs that stabilize biomolecular interactions instead of blocking them?

🔗 In Silico Analysis of Potential Stabilizer Binding Sites at Protein–RNA Interfaces. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0016

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #DrugDiscovery #ComputationalBiology #RNA #MolecularBiology #Bioinformatics #DrugDesign #SystemsBiology #MedicinalChemistry

Cell Painting is a scalable, image-based cellular profiling method that utilizes fluorescent dyes and artificial intelligence to measure thousands of molecular and structural changes in human cells following chemical exposure.
#Toxicology #Pharmacology #CellBiology #ComputationalBiology #sflorg
https://www.sflorg.com/2026/03/phar03312601.html

Jobs That Exist Only Because of AI in Biology! 🚀
AI Bioinformatician, Drug Discovery AI Specialist, Genomics Data Scientist.
Prepare with BioResire: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#AIBiologyJobs #BioResire #FutureBiologyJobs #AIBioinformatics #DrugDiscoveryAI #ComputationalBiology #GenomicsDataScientist #AIinBiology #BioinformaticsCareers #LifeSciencesJobs #IndiaAIJobs #BioinformaticsAI #NewBiologyJobs #STEMFuture #BioResireFuture #DataScientistBiology #AIJobsBiology #WhatsAppCommunity #Biology

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦠 Could algorithms help us outpace evolving superbugs?

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics

"I Am Rejected" – The harsh reality for many biotech graduates after job apps.
Hundreds of applications, multiple rejections, missing computational skills.
Upgrade now with BioResire: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#BiotechJobs #BioResire #JobRejection #BiotechGraduates #ComputationalBiology #Bioinformatics #IndiaBiotech #LifeScienceJobs #PhDBiotech #BiotechCareers #SkillUpgrade #JobSearchIndia #BiotechSkills #ResearchJobs #BioinformaticsTraining #STEMJobs #WhatsAppCommunity #BioResireStudents

🧱 What if activation and inhibition are not about binding but about motion?

🔗 Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines

Lakh packages in bioinformatics? Yes—with right skills!
Genomics, NGS, AI tools unlock pharma & research jobs.
Join students: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#BioinformaticsJobs #BioResire #HighPackage #BioinformaticsSalary #IndiaBioinformatics #BiotechJobs #NGSData #GenomicsJobs #LifeSciences #PharmaCareers #ResearchJobs #AIinBioinfo #BioinformaticsSkills #BioResireStudents #LakhPackage #BioTechSalary #ComputationalBiology #BioinformaticsIndia #WhatsAppCommunity #CareerHighSalary

Lakh packages in bioinformatics? Yes—with right skills!
Genomics, NGS, AI tools unlock pharma & research jobs.
Join students: https://whatsapp.com/channel/0029Vb5u2Tp77qVTb1D7bu3r

#BioinformaticsJobs #BioResire #HighPackage #BioinformaticsSalary #IndiaBioinformatics #BiotechJobs #NGSData #GenomicsJobs #LifeSciences #PharmaCareers #ResearchJobs #AIinBioinfo #BioinformaticsSkills #BioResireStudents #LakhPackage #BioTechSalary #ComputationalBiology #BioinformaticsIndia #WhatsAppCommunity #CareerHighSalary

🤯 What if most “biological insights” are just mixed-up signals we never untangled?

🔗 Integrative Learning of Disentangled Representations from Single-Cell RNA-Sequencing Datasets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0015

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SystemsBiology #Genomics #Bioinformatics #ComputationalBiology #AIinBiology #SingleCell #MachineLearning #DataScience #LifeSciences

🤯 What if most “biological insights” are just mixed-up signals we never untangled?

🔗 Integrative Learning of Disentangled Representations from Single-Cell RNA-Sequencing Datasets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0015

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SystemsBiology #Genomics #Bioinformatics #ComputationalBiology #AIinBiology #SingleCell #MachineLearning #DataScience #LifeSciences

🧬 Can we map the cascade of gene activity that guides cells through differentiation?

🔗 Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0007

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SingleCell #Genomics #Bioinformatics #SystemsBiology #GeneExpression #ComputationalBiology

🧬 Can we map the cascade of gene activity that guides cells through differentiation?

🔗 Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0007

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#SingleCell #Genomics #Bioinformatics #SystemsBiology #GeneExpression #ComputationalBiology