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#computationalbiology — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #computationalbiology, aggregated by home.social.

  1. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  2. Xenobots are microscopic, programmable biological machines constructed entirely from living cells without any genetic modification. Measuring less than a millimeter, they lack traditional mechanical parts and are entirely organic, biodegradable, and derived primarily from embryonic stem cells of the African clawed frog (Xenopus laevis).
    #WhatIs #EvolutionaryBiology #DevelopmentalBiology #SyntheticBiology #ComputationalBiology #SoftRobotics
    sflorg.com/2026/05/wi05172601.

  3. A newly decoded, gene-encoded blueprint functions as a spatial "wiring map" that guides growing nerve fibers (axons) to connect with the precise target regions in the developing brain.
    #Neuroscience #Genetics #ComputationalBiology #DevelopmentalBiology #sflorg
    sflorg.com/2026/05/ns05142601.

  4. 💊 Can understanding receptor bias help us design safer, more selective GPCR drugs?

    🔗 Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2024.10

    📚 CSBJ: csbj.org/

    #GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

  5. 🧬 Can a single method balance sensitivity and specificity in small RNA annotation across the tree of life?

    🔗 Class-agnostic annotation of small RNAs balances sensitivity and specificity in diverse organisms. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.05

    📚 CSBJ: csbj.org/

    #RNA #Bioinformatics #Genomics #SmallRNAs #ComputationalBiology #Transcriptomics #MolecularBiology #Epigenetics

  6. Now Katie Pollard from UCSF
    docpollard.org/

    Resolving single-cell regulatory elements across species and contexts with CellWalker2

    lab builds #statistical models and #ComputationalBiology tools
    #neuroscience

    did microdissection then single-cell ATAC-seq
    developed CellWalker to solve challenges in resolving regulatory elements
    genomebiology.biomedcentral.co

    #GeneExpression
    #genomics
    #SingleCell
    #CSSingleCells23

    1/2

  7. First speaker: Jingyi Jessica Li, UCLA
    jsb.ucla.edu/

    Enhancing #statistical rigor in single-cell data analysis using synthetic negative controls

    "In #genomics, the negative control is often not so obvious"

    How to choose null hypothesis? question is often "too abstract for biologists" 🤓

    Now discussing (infamous) problems with dubious use of t-SNE

    developed tool called scDEED
    biorxiv.org/content/10.1101/20

    #CSSingleCells23
    #ComputationalBiology
    #statistics

    1/2

  8. Now Neda Bagheri at U of Washington
    bagherilab.com/

    Emulating emergent spatio-temporal cell population dynamics with #machinelearning algorithms remains challenging

    Population dynamics arise from autonomous #SingleCell decisions
    e.g. in context of #cancer progression

    Created tool called ARCADE = Agent-based Representation of Cells And Dynamic Environments
    bagherilab.com/resources.php

    But model is computationally expensive...
    1/2

    #ComputationalBiology
    #SystemsBiology
    #CSSingleCells23

  9. After a day trying this out I decided to do a proper #introduction. I never was an active twitter user but this is looking much more interesting to me.

    I'm 26 years old. I'm a PhD student at the #UniversidadDeValparaiso , #Chile While my native tongue is Chilean Spanish I tend to keep my online accounts in English.

    *Research topics* I study #Biophysics and #ComputationalBiology. I do #MolecularDynamics simulations of #CarbonNanomaterials and #BioMolecules, mostly with #GROMOS .

    *Computer stuff* I'm an #Emacs enthusiast running #doomemacs . #linux daily driver. I know #python and some #julia and I'm learning a bit of #C++ and #elisp . Recently got into keyboards and switched to a moonlander (split kb) and the #colemakdh layout .

    *Hobbies* As you might've guessed, I'm into nerdy stuff. I dabble into #ttrpg (prefer #pathfinder 2e rather than #DnD) and #tcg (Primarily #digimon, and recently #marvelsnap). I read a ton of #manga and sometimes watch #anime. I play videogames on both #pc and #nintendo #switch