#sirna — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #sirna, aggregated by home.social.
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The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks -
The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks -
Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe
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Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe
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Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad -
Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad -
Protecting #crops: #RNA-based substances open up new avenue to combat a widespread #plant #virus.
#mosaic_virus #agriculture #food_security #aphids #vectors #siRNA #edsRNA
https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html
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Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.
Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.
Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.
Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.
Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET
Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.
Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET
Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.
Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y
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#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.
This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).
https://www.nature.com/articles/s41573-020-0075-7
Paper:
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#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.
This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).
https://www.nature.com/articles/s41573-020-0075-7
Paper:
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Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi
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Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi
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We just put in a manuscript using #siRNA for knockdown. Knockdown verified with RT-PCR and Western blot. Saw a phenotype. Rescued it with ectopic expression of the knocked down protein. A reviewer required us to repeat the experiments using #CRISPR, and why we didn''t use crispr in the first place ?#thatsecondreviewer
#academia #cellbiology
A: Because we didn't need to, <expletive>. -
We just put in a manuscript using #siRNA for knockdown. Knockdown verified with RT-PCR and Western blot. Saw a phenotype. Rescued it with ectopic expression of the knocked down protein. A reviewer required us to repeat the experiments using #CRISPR, and why we didn''t use crispr in the first place ?#thatsecondreviewer
#academia #cellbiology
A: Because we didn't need to, <expletive>. -
Paper from our team about #siRNA and #COVID19. Already published last year, but maybe still relevant 😌🙂. A Computational Design of siRNA in SARS-CoV-2 Spike Glycoprotein Gene and Its Binding Capability toward mRNA https://journal.ugm.ac.id/ijc/article/view/68415/0
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Paper from our team about #siRNA and #COVID19. Already published last year, but maybe still relevant 😌🙂. A Computational Design of siRNA in SARS-CoV-2 Spike Glycoprotein Gene and Its Binding Capability toward mRNA https://journal.ugm.ac.id/ijc/article/view/68415/0
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Este meme sale en mi próximo artículo/charla sobre microARN. XDDD #xp
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RT @DNA_RNA_Uni
I laughed so hard 😆😅😚#RNAi #siRNA #miRNA #featuredpaper https://mdpi.com/1422-0067/23/23/14755
https://twitter.com/DNA_RNA_Uni/status/1597927406136086528 -
Este meme sale en mi próximo artículo/charla sobre microARN. XDDD #xp
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RT @DNA_RNA_Uni
I laughed so hard 😆😅😚#RNAi #siRNA #miRNA #featuredpaper https://mdpi.com/1422-0067/23/23/14755
https://twitter.com/DNA_RNA_Uni/status/1597927406136086528 -
Aedes aegypti Dicer2 mutants
"Our Dicer2 null mutant line is viable and fertile, and only displays minor fitness defects despite being unable to produce siRNAs. The loss of Dicer2 affects early viral replication and systemic viral dissemination of four medically significant arboviruses (chikungunya, Mayaro, dengue, and #zika viruses) representing two viral families. However, measures of virus transmission potential indicate that Dicer2 null mutants and wild-type mosquitoes display an overall similar level of vector competence. Additionally, Dicer2 null mutants undergo significant virus-induced mortality during infection with #chikungunya virus, but not #dengue virus."
#siRNA #crispr #preprint