#sirna — Public Fediverse posts

https://www.europesays.com/ie/670927/ Microscopic peptide droplets reduce colorectal tumor growth in mice #Antibodies #Antibody #cancer #Cell #Colorectal #ColorectalCancer #Éire #Gene #IE #ImmuneSystem #immunotherapy #Ireland #Manufacturing #medicine #MonoclonalAntibody #PDL1 #Research #RNA #siRNA #Technology

What if, instead of spending years optimizing small molecule chemistry to treat just one disease,
there really was a magic button to switch off any gene we chose?

In that case, we could treat
dozens of deadly diseases,
from Alzheimer’s to diabetes
to Huntington’s disease.

Welcome to the world of #siRNA therapy.

The story of siRNA begins in 1990,
when the scientists at the DNA Plant Technology Corporation in California
were trying to figure out why their petunias turned white.
They had actually been trying to make their petunias darker,
by adding an extra copy of the gene for an enzyme that produces pigment.

Presumably, adding an extra copy of a gene for an enzyme would mean more enzyme and therefore more pigment.
But somehow, the extra copy eliminated the enzyme’s production, rather than boosting it.

They named this baffling effect ‘cosuppression’.
Subsequent work by other researchers revealed its cause:
a special kind of RNA molecule,
siRNA, had interfered with the enzyme’s production.
Andrew Fire and Craig Mello later won a Nobel prize for this discovery.

Biologists had already known about RNA for several decades.
Similar to DNA, RNA is a complex molecule built from a chain of smaller building blocks that encode genetic information.
But the two differ in one important detail:
the building blocks of RNA have one extra oxygen atom compared to DNA
(hence its name, ribonucleic acid, as opposed to DNA’s ‘deoxy’-ribonucleic acid).
This oxygen is prone to chemical reactions that can break RNA molecules.

DNA is stabler and is therefore used to store genetic information in all multicellular life.
RNA molecules tend to be short-lived,
and take many different forms within cells,
carrying instructions,
helping to assemble proteins,
regulating genes,
and catalyzing reactions.

And while DNA is ‘double-stranded’, with two linked strands of building blocks twisting into its famous helix shape,
RNA often exists as just one strand.

DNA contains the instructions for making proteins,
from the enzymes that digest food to the keratin and collagen that form our hair and skin.
But to get from DNA to protein,
the genetic code is first transcribed into an intermediate RNA molecule,
called ‘messenger RNA’ or mRNA,
which is then translated into protein.

If the mRNA is destroyed, the protein won’t be built.
That’s exactly what siRNA, or ‘small interfering RNA’, does:
it’s a short strand of RNA that interferes with the production of protein by destroying mRNA.
An siRNA molecule binds to a piece of mRNA with a matching sequence,
like a kind of barcode,
and targets it for destruction by the cell’s gene-silencing machinery,
which cuts the mRNA into pieces

siRNA also explains what happened in the petunias.

Adding an extra copy of the pigment-producing gene triggered the petunias to develop siRNA targeting that sequence,

and because the newly introduced gene and the original gene shared the same sequence,
both were silenced,

the flowers lost their pigment and turned white.

This is a naturally occurring process:

siRNA is used to ‘silence’ unwanted genes,
such as those of viruses that have entered the cell.

But we can also use it to artificially block the production of proteins that cause disease
https://www.worksinprogress.news/p/switch-off-a-gene-of-your-choice

What if, instead of spending years optimizing small molecule chemistry to treat just one disease,
there really was a magic button to switch off any gene we chose?

In that case, we could treat
dozens of deadly diseases,
from Alzheimer’s to diabetes
to Huntington’s disease.

Welcome to the world of #siRNA therapy.

The story of siRNA begins in 1990,
when the scientists at the DNA Plant Technology Corporation in California
were trying to figure out why their petunias turned white.
They had actually been trying to make their petunias darker,
by adding an extra copy of the gene for an enzyme that produces pigment.

Presumably, adding an extra copy of a gene for an enzyme would mean more enzyme and therefore more pigment.
But somehow, the extra copy eliminated the enzyme’s production, rather than boosting it.

They named this baffling effect ‘cosuppression’.
Subsequent work by other researchers revealed its cause:
a special kind of RNA molecule,
siRNA, had interfered with the enzyme’s production.
Andrew Fire and Craig Mello later won a Nobel prize for this discovery.

Biologists had already known about RNA for several decades.
Similar to DNA, RNA is a complex molecule built from a chain of smaller building blocks that encode genetic information.
But the two differ in one important detail:
the building blocks of RNA have one extra oxygen atom compared to DNA
(hence its name, ribonucleic acid, as opposed to DNA’s ‘deoxy’-ribonucleic acid).
This oxygen is prone to chemical reactions that can break RNA molecules.

DNA is stabler and is therefore used to store genetic information in all multicellular life.
RNA molecules tend to be short-lived,
and take many different forms within cells,
carrying instructions,
helping to assemble proteins,
regulating genes,
and catalyzing reactions.

And while DNA is ‘double-stranded’, with two linked strands of building blocks twisting into its famous helix shape,
RNA often exists as just one strand.

DNA contains the instructions for making proteins,
from the enzymes that digest food to the keratin and collagen that form our hair and skin.
But to get from DNA to protein,
the genetic code is first transcribed into an intermediate RNA molecule,
called ‘messenger RNA’ or mRNA,
which is then translated into protein.

If the mRNA is destroyed, the protein won’t be built.
That’s exactly what siRNA, or ‘small interfering RNA’, does:
it’s a short strand of RNA that interferes with the production of protein by destroying mRNA.
An siRNA molecule binds to a piece of mRNA with a matching sequence,
like a kind of barcode,
and targets it for destruction by the cell’s gene-silencing machinery,
which cuts the mRNA into pieces

siRNA also explains what happened in the petunias.

Adding an extra copy of the pigment-producing gene triggered the petunias to develop siRNA targeting that sequence,

and because the newly introduced gene and the original gene shared the same sequence,
both were silenced,

the flowers lost their pigment and turned white.

This is a naturally occurring process:

siRNA is used to ‘silence’ unwanted genes,
such as those of viruses that have entered the cell.

But we can also use it to artificially block the production of proteins that cause disease
https://www.worksinprogress.news/p/switch-off-a-gene-of-your-choice

What if, instead of spending years optimizing small molecule chemistry to treat just one disease,
there really was a magic button to switch off any gene we chose?

In that case, we could treat
dozens of deadly diseases,
from Alzheimer’s to diabetes
to Huntington’s disease.

Welcome to the world of #siRNA therapy.

The story of siRNA begins in 1990,
when the scientists at the DNA Plant Technology Corporation in California
were trying to figure out why their petunias turned white.
They had actually been trying to make their petunias darker,
by adding an extra copy of the gene for an enzyme that produces pigment.

Presumably, adding an extra copy of a gene for an enzyme would mean more enzyme and therefore more pigment.
But somehow, the extra copy eliminated the enzyme’s production, rather than boosting it.

They named this baffling effect ‘cosuppression’.
Subsequent work by other researchers revealed its cause:
a special kind of RNA molecule,
siRNA, had interfered with the enzyme’s production.
Andrew Fire and Craig Mello later won a Nobel prize for this discovery.

Biologists had already known about RNA for several decades.
Similar to DNA, RNA is a complex molecule built from a chain of smaller building blocks that encode genetic information.
But the two differ in one important detail:
the building blocks of RNA have one extra oxygen atom compared to DNA
(hence its name, ribonucleic acid, as opposed to DNA’s ‘deoxy’-ribonucleic acid).
This oxygen is prone to chemical reactions that can break RNA molecules.

DNA is stabler and is therefore used to store genetic information in all multicellular life.
RNA molecules tend to be short-lived,
and take many different forms within cells,
carrying instructions,
helping to assemble proteins,
regulating genes,
and catalyzing reactions.

And while DNA is ‘double-stranded’, with two linked strands of building blocks twisting into its famous helix shape,
RNA often exists as just one strand.

DNA contains the instructions for making proteins,
from the enzymes that digest food to the keratin and collagen that form our hair and skin.
But to get from DNA to protein,
the genetic code is first transcribed into an intermediate RNA molecule,
called ‘messenger RNA’ or mRNA,
which is then translated into protein.

If the mRNA is destroyed, the protein won’t be built.
That’s exactly what siRNA, or ‘small interfering RNA’, does:
it’s a short strand of RNA that interferes with the production of protein by destroying mRNA.
An siRNA molecule binds to a piece of mRNA with a matching sequence,
like a kind of barcode,
and targets it for destruction by the cell’s gene-silencing machinery,
which cuts the mRNA into pieces

siRNA also explains what happened in the petunias.

Adding an extra copy of the pigment-producing gene triggered the petunias to develop siRNA targeting that sequence,

and because the newly introduced gene and the original gene shared the same sequence,
both were silenced,

the flowers lost their pigment and turned white.

This is a naturally occurring process:

siRNA is used to ‘silence’ unwanted genes,
such as those of viruses that have entered the cell.

But we can also use it to artificially block the production of proteins that cause disease
https://www.worksinprogress.news/p/switch-off-a-gene-of-your-choice

What if, instead of spending years optimizing small molecule chemistry to treat just one disease,
there really was a magic button to switch off any gene we chose?

In that case, we could treat
dozens of deadly diseases,
from Alzheimer’s to diabetes
to Huntington’s disease.

Welcome to the world of #siRNA therapy.

The story of siRNA begins in 1990,
when the scientists at the DNA Plant Technology Corporation in California
were trying to figure out why their petunias turned white.
They had actually been trying to make their petunias darker,
by adding an extra copy of the gene for an enzyme that produces pigment.

Presumably, adding an extra copy of a gene for an enzyme would mean more enzyme and therefore more pigment.
But somehow, the extra copy eliminated the enzyme’s production, rather than boosting it.

They named this baffling effect ‘cosuppression’.
Subsequent work by other researchers revealed its cause:
a special kind of RNA molecule,
siRNA, had interfered with the enzyme’s production.
Andrew Fire and Craig Mello later won a Nobel prize for this discovery.

Biologists had already known about RNA for several decades.
Similar to DNA, RNA is a complex molecule built from a chain of smaller building blocks that encode genetic information.
But the two differ in one important detail:
the building blocks of RNA have one extra oxygen atom compared to DNA
(hence its name, ribonucleic acid, as opposed to DNA’s ‘deoxy’-ribonucleic acid).
This oxygen is prone to chemical reactions that can break RNA molecules.

DNA is stabler and is therefore used to store genetic information in all multicellular life.
RNA molecules tend to be short-lived,
and take many different forms within cells,
carrying instructions,
helping to assemble proteins,
regulating genes,
and catalyzing reactions.

And while DNA is ‘double-stranded’, with two linked strands of building blocks twisting into its famous helix shape,
RNA often exists as just one strand.

DNA contains the instructions for making proteins,
from the enzymes that digest food to the keratin and collagen that form our hair and skin.
But to get from DNA to protein,
the genetic code is first transcribed into an intermediate RNA molecule,
called ‘messenger RNA’ or mRNA,
which is then translated into protein.

If the mRNA is destroyed, the protein won’t be built.
That’s exactly what siRNA, or ‘small interfering RNA’, does:
it’s a short strand of RNA that interferes with the production of protein by destroying mRNA.
An siRNA molecule binds to a piece of mRNA with a matching sequence,
like a kind of barcode,
and targets it for destruction by the cell’s gene-silencing machinery,
which cuts the mRNA into pieces

siRNA also explains what happened in the petunias.

Adding an extra copy of the pigment-producing gene triggered the petunias to develop siRNA targeting that sequence,

and because the newly introduced gene and the original gene shared the same sequence,
both were silenced,

the flowers lost their pigment and turned white.

This is a naturally occurring process:

siRNA is used to ‘silence’ unwanted genes,
such as those of viruses that have entered the cell.

But we can also use it to artificially block the production of proteins that cause disease
https://www.worksinprogress.news/p/switch-off-a-gene-of-your-choice

What if, instead of spending years optimizing small molecule chemistry to treat just one disease,
there really was a magic button to switch off any gene we chose?

In that case, we could treat
dozens of deadly diseases,
from Alzheimer’s to diabetes
to Huntington’s disease.

Welcome to the world of #siRNA therapy.

The story of siRNA begins in 1990,
when the scientists at the DNA Plant Technology Corporation in California
were trying to figure out why their petunias turned white.
They had actually been trying to make their petunias darker,
by adding an extra copy of the gene for an enzyme that produces pigment.

Presumably, adding an extra copy of a gene for an enzyme would mean more enzyme and therefore more pigment.
But somehow, the extra copy eliminated the enzyme’s production, rather than boosting it.

They named this baffling effect ‘cosuppression’.
Subsequent work by other researchers revealed its cause:
a special kind of RNA molecule,
siRNA, had interfered with the enzyme’s production.
Andrew Fire and Craig Mello later won a Nobel prize for this discovery.

Biologists had already known about RNA for several decades.
Similar to DNA, RNA is a complex molecule built from a chain of smaller building blocks that encode genetic information.
But the two differ in one important detail:
the building blocks of RNA have one extra oxygen atom compared to DNA
(hence its name, ribonucleic acid, as opposed to DNA’s ‘deoxy’-ribonucleic acid).
This oxygen is prone to chemical reactions that can break RNA molecules.

DNA is stabler and is therefore used to store genetic information in all multicellular life.
RNA molecules tend to be short-lived,
and take many different forms within cells,
carrying instructions,
helping to assemble proteins,
regulating genes,
and catalyzing reactions.

And while DNA is ‘double-stranded’, with two linked strands of building blocks twisting into its famous helix shape,
RNA often exists as just one strand.

DNA contains the instructions for making proteins,
from the enzymes that digest food to the keratin and collagen that form our hair and skin.
But to get from DNA to protein,
the genetic code is first transcribed into an intermediate RNA molecule,
called ‘messenger RNA’ or mRNA,
which is then translated into protein.

If the mRNA is destroyed, the protein won’t be built.
That’s exactly what siRNA, or ‘small interfering RNA’, does:
it’s a short strand of RNA that interferes with the production of protein by destroying mRNA.
An siRNA molecule binds to a piece of mRNA with a matching sequence,
like a kind of barcode,
and targets it for destruction by the cell’s gene-silencing machinery,
which cuts the mRNA into pieces

siRNA also explains what happened in the petunias.

Adding an extra copy of the pigment-producing gene triggered the petunias to develop siRNA targeting that sequence,

and because the newly introduced gene and the original gene shared the same sequence,
both were silenced,

the flowers lost their pigment and turned white.

This is a naturally occurring process:

siRNA is used to ‘silence’ unwanted genes,
such as those of viruses that have entered the cell.

But we can also use it to artificially block the production of proteins that cause disease
https://www.worksinprogress.news/p/switch-off-a-gene-of-your-choice

https://www.europesays.com/it/658245/ Tumori del pancreas e della prostata: esosomi “corrieri” di RNA per spegnere i geni malati. La terapia arriva alla prova sull’uomo. #CarcinomaPancreatico #esosomi #Health #iExoKrasG12D #ipilimumab #IT #Italia #Italy #johannesburg #KrasG12d #NatureCommunications #PubMed #Salute #siRNA #TumoreDelPancreas #TumoreDellaProstata #UniversitàDelWitwatersrand

Seoul City University team develops high-load RNA delivery to cut triglycerides for 4 weeks

A technology has been developed that overcomes the loading and efficacy limits of lipid nanoparticle carriers. Provided by…
#EuropeSays #Korea #KR #Seoul #delivery-carrier #lipid-nanoparticles #metabolic-diseases #NationalResearchFoundationofKorea #ribonucleic-acid #RNA #siRNA #therapeutics #UniversityofSeoul #대사질환 #리보핵산 #서울시립대 #전달체 #지질나노입자 #치료제 #한국연구재단
https://www.europesays.com/korea/135711/

https://www.europesays.com/ie/560551/ Scientists capture atomic images to improve RNA interference drug design #Cholesterol #Drugs #Éire #Genes #IE #Ireland #LivingCells #medicine #MolecularBiology #Physiology #Protein #Research #RNA #RNAInterference #Science #siRNA

OliX Signs New Partnership With L’Oréal to Expand Nail Health Research

Lee Dong-ki, CEO of Olix. Photo courtesy of Olix OliX (226950.KQ), a Korean RNA interference (RNAi) therapeutics company,…
#France #FR #Europe #EU #L'Oréal #beautysciencepartnership #BOLDventurefund #Koreabiotech #l'oreal #nailhealthresearch #Olix #RNAiplatform #siRNA
https://www.europesays.com/france/43001/

https://www.europesays.com/ch/82235/ Novartis dystrophy data tee up regulatory talks on Avidity drug #biotech #ClinicalData #FierceBiotechHomepage #MuscularDystrophy #Novartis #RareDiseases #siRNA

https://www.europesays.com/ie/424450/ Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma #Apoptosis #blood #BloodVessels #Brain #cancer #Cell #DNA #Éire #Enzyme #Genetic #Genomic #Glioblastoma #Health #IE #Ireland #medicine #Neuroblastoma #Neurons #Neuroscience #NitricOxide #Phosphorylation #Protein #Research #siRNA #Stress #Tumor #website #Xenograft

https://www.europesays.com/ch/31680/ Novartis invests US$200min lacklustre Parkinson’s target #AlphaSynuclein #Arrowhead #LicenceDeal #MonoclonalAntibodies #Novartis #Parkinson'sDisease #siRNA

https://www.europesays.com/ie/351158/ New Bio-Implant for Spinal Cord Repair #Bioengineering #Éire #Genetics #Health #IE #Ireland #neuroplasticity #Neuroscience #neurotech #PTENGene #rcsi #RegenerativeMedicine #SCI #siRNA #SpinalCordInjury #TissueEngineering

https://www.europesays.com/ie/326098/ RNA micelles enable targeted chemotherapy without immune toxicity #cancer #Cell #chemotherapy #Colorectal #ColorectalCancer #Drugs #Éire #Gemcitabine #Gene #Health #IE #ImmuneResponse #Ireland #Ligand #Lungs #Metastasis #Molecule #Nanoparticle #Pharmacology #Research #RNA #siRNA #Technology #Therapeutics #therapy #Tumor

The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks

The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks

The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks

The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks

The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA
#BeilsteinTalks

Breakthrough in nanoparticle technology could expand access to biologic medicines https://www.byteseu.com/1264785/ #Chemicals #Cold #COVID19 #Drugs #LivingCells #Nanoparticle #Nanoparticles #Protein #RNA #siRNA #Technology #Tumor #vaccine

Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe

Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe

Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe

Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe

Most genetic screens characterize host factors important for early stages of #viral #infection. This study uses a genome-scale #siRNA screen designed to uncover key pathways influencing early & late stages of #SARSCoV2 infection, including non-canonical NF-κB pathway @PLOSBiology https://plos.io/3ZX0fRe

Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia  
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/

Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia  
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/

Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia  
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/

Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia  
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/

Qfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia  
Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............
#Bleedingdisorders #FDA #Fitusiran #Haemophilia #Hemophilia #Qfitlia #siRNA
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/

Protecting #crops: #RNA-based substances open up new avenue to combat a widespread #plant #virus.

#mosaic_virus #agriculture #food_security #aphids #vectors #siRNA #edsRNA

https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html

Protecting #crops: #RNA-based substances open up new avenue to combat a widespread #plant #virus.

#mosaic_virus #agriculture #food_security #aphids #vectors #siRNA #edsRNA

https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html

Protecting #crops: #RNA-based substances open up new avenue to combat a widespread #plant #virus.

#mosaic_virus #agriculture #food_security #aphids #vectors #siRNA #edsRNA

https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html

Protecting #crops: #RNA-based substances open up new avenue to combat a widespread #plant #virus.

#mosaic_virus #agriculture #food_security #aphids #vectors #siRNA #edsRNA

https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html

Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Starting TOMORROW, 📅 Nov. 14, 2024, at 🕒 2:30 PM CET: "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Register for FREE 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Join the online #BeilsteinTalk "Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, on 📅 Nov. 14, 2024 🕒 2:30–3:30 PM CET.

Participation is FREE! Just register: 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET

Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET

Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET

Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET

Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

Save the date: 📅 Nov. 14, 2024 🕒 2:30–3:30 pm CET

Online #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/nanotechnology-computational-approaches-in-improving-spermine-based-rna-nanocarriers?M=y

#DrugDelivery #siRNA
#BeilsteinTalks

#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.

This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).

https://ispe.org/pharmaceutical-engineering/november-december-2020/current-state-oligonucleotide-therapeutics

https://www.nature.com/articles/s41573-020-0075-7

Paper:

https://www.nature.com/articles/s41573-020-0075-7.pdf

#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.

This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).

https://ispe.org/pharmaceutical-engineering/november-december-2020/current-state-oligonucleotide-therapeutics

https://www.nature.com/articles/s41573-020-0075-7

Paper:

https://www.nature.com/articles/s41573-020-0075-7.pdf

#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.

This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).

https://ispe.org/pharmaceutical-engineering/november-december-2020/current-state-oligonucleotide-therapeutics

https://www.nature.com/articles/s41573-020-0075-7

Paper:

https://www.nature.com/articles/s41573-020-0075-7.pdf

#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.

This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).

https://ispe.org/pharmaceutical-engineering/november-december-2020/current-state-oligonucleotide-therapeutics

https://www.nature.com/articles/s41573-020-0075-7

Paper:

https://www.nature.com/articles/s41573-020-0075-7.pdf

#Oligonucleotides are a relatively new( #novel ) class of #drugs that can modulate #gene expression through various mechanisms like #RNA interference, degradation, or splice-modulation.

This includes drugs like small interfering RNA (#siRNA), #microRNA (miRNA), and antisense oligonucleotides (ASOs).

https://ispe.org/pharmaceutical-engineering/november-december-2020/current-state-oligonucleotide-therapeutics

https://www.nature.com/articles/s41573-020-0075-7

Paper:

https://www.nature.com/articles/s41573-020-0075-7.pdf

Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi

Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi

Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi

Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi

Tulisan sains populer mengenai desain #siRNA untuk desain agen terapetik. Semoga bermanfaat! 🙏 https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik #bioinformatika #biomedik #bioteknologi