#bc2basel — Public Fediverse posts

We’ve reached the last session of [BC]² 2025 with the closing keynote address from Julia Merkenschlager who is presenting (remotely) on immunology. Title of her talk: “Affinity maturation: Against the odds” #bc2basel

Our [BC]²INGO GAME was won by Nosihle Msomi. Congratulations! #bc2basel

Congratulations to poster prize winners:

Cassandra Litchfield​
Alen Stambolliu​
Benjamin Heiniger​
Laura Voitl​
Océane Follonier​
Siyuan Luo​
Qingyao Huang​

#bc2basel

🧬 Turning science into startups! A special session on launching #bioinformatics startups with insights on IP, legal, funding + case studies (BigOmics Analytics, TrueYouOmics) from experts Swiss Federal Institute of Intellectual Property, Lenz & Staehelin law firm, Innosuisse. Session chairs: @abdullah, Elif Özkırımlı and Vincent Zoete. #bc2basel

We love putting together [BC]² Basel Computational Biology Conference #bc2basel for you every two years.
And we do so much more! Come by our booth to find out about our vision for life-science data and all the services we offer academia and industry.

We now have highlights of the latest research submitted in abstracts: from venom evolution & spatial lipidomics to deep learning, glioma cell states & rapid diagnostics for rare disease. Chaired by Katja Bärenfaller and David Gfeller
#bc2basel #Bioinformatics #Omics #MachineLearning

Gavriilidou: proteins which are co-expressed in venom glands (work done with Giulia Zancolli @dee_unil) are also co-evolving
#bc2basel

Gavriilidou obtained ≈3k co-evolution networks between venoms and other protein families. E.g. dense cluster of 5 venom protein families co-evolving with each other and with many other protein families. The co-evolving proteins include venom-related functions as well as resistance-related functions. #bc2basel

Gavriilidou investigates co-evolution of venomous predators and their preys by phylogenetic profiling, using HogProf https://doi.org/10.1371/journal.pcbi.1007553 #bc2basel

Athina Gavriilidou next, on a topic dear to my heart, evolution of venom 🕷️🐍 #bc2basel

Preprints and server from Craighero's work:
https://www.biorxiv.org/content/10.1101/2025.04.03.646988v1
https://www.biorxiv.org/content/10.1101/2024.04.08.588507v3
https://lts2.epfl.ch/ribotly/
#bc2basel

Craighero: "unfortunately I don't have an AI generated image for this, but imagine a ribosome made of cheese or whatever" 😁 #bc2basel

#bc2basel "Highlights - Top abstracts across all scientific themes", starting with Francesco Craighero @fcraighero.bsky.social, using deep learning to understand the regulation of translation elongation, i.e. ribosome stalling.

In ‘Integrative Bioinformatics for Evolutionary and Environmental Processes’ our invited speaker is Eline Lorenzen from University of Copenhagen, Denmark. This session is chaired by Anne-Florence Bitbol and Anna-Sapfo Malaspinas. #bc2basel

Lorenzen: from Arctic sedimentary DNA, reconstruct communities of (marine mammal) species. E.g., with opening of Nares straight at start of inter-glacial, we find DNA of temperate species such as seals. #bc2basel

Lorenzen: unlike polar bears, Bowhead whales had stable environment suitability and genomic population size until very recently. Then human hunting (whaling) arrived, leading to a demographic crash. Modeling predicts that population recovery will be very slow at best. #bc2basel

Lorenzen: Parallel punctuated declines of reconstructed Polar bear habitat, and of population size from genomic data. Small declines in habitat suitability lead to massive declines in population size. #bc2basel

The Arctic is changing fast! In a few years, there will be an ice-free Arctic in the summer https://www.arcticdeathspiral.org/ #bc2basel

Eline Lorenzen, ancient DNA: to understand dynamics of terrestrial mammals, it is difficult to disentangle direct and indirect influence of humans, and environmental changes. For marine species, until recently very little human impact, thus we can see environmental change. #bc2basel

It’s the last day of this year’s [BC]² conference and attendees are gathering for the final parallel sessions:
- Integrative Bioinformatics for Evolutionary and Environmental Processes
- Computational methods for single-cell and spatial omics: from data to biological insights
#bc2basel

Our second keynote address is given by Peer Bork (EMBL Heildelberg, Germany) under the title “Microbiome analysis for human and planetary health”. #bc2basel

Time for the posters to be presented: enter the gallery and have a look! There's 🍰🧁🎂 #bc2basel

Our invited speaker for ‘Clinical data science: advancements in diagnostics and patient care’ is Päivi Östling (Karolinska Institute, SciLifeLab, Sweden). The session is chaired by Laura Azzimonti and Valérie Barbié. #bc2basel

For ‘Protein design and modeling molecular assemblies: breakthroughs and applications in computational structural biology’ our invited speaker is ‪Elodie Laine from Sorbonne University, France. The session is chaired by Pedro Beltrao and Janani Durairaj #bc2basel

Time for our second set of parallel sessions, which feature the latest on protein design and modeling molecular assemblies, and clinical data science advancements in diagnostics and patient care. #bc2basel

The SIB Remarkable Outputs 2024 are out! Explore 8 standout bioinformatics tools & discoveries from the SIB community: AI for enzymes, T-cell models & more. Congratulations to all teams!

Discover them all: https://www.sib.swiss/news/discover-the-sib-remarkable-outputs-2024

#Bioinformatics #SIBRemarkableOutputs2024 #OpenScience #bc2basel

Love the social media efforts and community building of @scverse !
https://scverse.org/join/
https://scverse.org/events/
#bc2basel

Congrats to all the winners!

You could be next!

Find out more about the SIB Bioinformatics Awards and sign up for our newsletter to be notified when the call for entries opens in 2027: http://sib.swiss/bioinformatics-awards #bc2basel #bioinformatics

💫The 2025 SIB Innovative Resource Award goes to @scverse!💫
The jury was impressed by the focus of these omics tools on interoperability, usability, and communication. The project’s solid governance and emphasis on open science principles are particularly commendable.

#Bioinformatics #SIBawards #bc2basel

Great to see an research engineer put forward for the @SIB Innovative Resource Award #bc2basel

📢 Today is your last chance to register! From #AI to #Evolution, #GeneExpression and #PrecisionMedicine, join us at the [BC]2 Basel Computational Biology Conference to hear about the latest #Bioinformatics & #CompBio trends.

📆 Deadline: 1 September 2025

👉 Register here: https://www.bc2.ch/registration-info

#bc2basel

💡 Want to make the most of cell line data? Join this #BC2Basel tutorial to explore Cellosaurus, from ontologies to APIs to real-world use cases.

🔹Taught by Amos Bairoch & Pierre-André Michel (SIB).

📅 Mon 8 Sep at #bc2

👉Register: tinyurl.com/5n8w3pwb

#bioinformatics #Cellosaurus #celllines #lifesciences #FAIRdata

💡 Want to make the most of cell line data? Join this #BC2Basel tutorial to explore Cellosaurus, from ontologies to APIs to real-world use cases.

🔹Taught by Amos Bairoch & Pierre-André Michel (SIB).

📅 Mon 8 Sep at #bc2

👉Register: tinyurl.com/5n8w3pwb

#bioinformatics #Cellosaurus #celllines #lifesciences #FAIRdata

💡 Want to make the most of cell line data? Join this #BC2Basel tutorial to explore Cellosaurus, from ontologies to APIs to real-world use cases.

🔹Taught by Amos Bairoch & Pierre-André Michel (SIB).

📅 Mon 8 Sep at #bc2

👉Register: tinyurl.com/5n8w3pwb

#bioinformatics #Cellosaurus #celllines #lifesciences #FAIRdata

💡 Want to make the most of cell line data? Join this #BC2Basel tutorial to explore Cellosaurus, from ontologies to APIs to real-world use cases.

🔹Taught by Amos Bairoch & Pierre-André Michel (SIB).

📅 Mon 8 Sep at #bc2

👉Register: tinyurl.com/5n8w3pwb

#bioinformatics #Cellosaurus #celllines #lifesciences #FAIRdata

💡 Want to make the most of cell line data? Join this #BC2Basel tutorial to explore Cellosaurus, from ontologies to APIs to real-world use cases.

🔹Taught by Amos Bairoch & Pierre-André Michel (SIB).

📅 Mon 8 Sep at #bc2

👉Register: tinyurl.com/5n8w3pwb

#bioinformatics #Cellosaurus #celllines #lifesciences #FAIRdata

💡 How can we harness functional homology & molecular similarity in protein and drug discovery, without falling into the pitfalls of data leakage?
Join this #BC2Basel workshop to explore practical strategies for robust, data-driven research

🔹Taught by Rebecca Buller (ZHAW), David Graber (ETH Zürich), Peter Stockinger (ZHAW)

📅 Mon 8 Sep at #bc2 👉Register: https://bc2.ch/registration-info

💡 How can we harness functional homology & molecular similarity in protein and drug discovery, without falling into the pitfalls of data leakage?
Join this #BC2Basel workshop to explore practical strategies for robust, data-driven research

🔹Taught by Rebecca Buller (ZHAW), David Graber (ETH Zürich), Peter Stockinger (ZHAW)

📅 Mon 8 Sep at #bc2 👉Register: https://bc2.ch/registration-info

💡 How can we harness functional homology & molecular similarity in protein and drug discovery, without falling into the pitfalls of data leakage?
Join this #BC2Basel workshop to explore practical strategies for robust, data-driven research

🔹Taught by Rebecca Buller (ZHAW), David Graber (ETH Zürich), Peter Stockinger (ZHAW)

📅 Mon 8 Sep at #bc2 👉Register: https://bc2.ch/registration-info

💡 How can we harness functional homology & molecular similarity in protein and drug discovery, without falling into the pitfalls of data leakage?
Join this #BC2Basel workshop to explore practical strategies for robust, data-driven research

🔹Taught by Rebecca Buller (ZHAW), David Graber (ETH Zürich), Peter Stockinger (ZHAW)

📅 Mon 8 Sep at #bc2 👉Register: https://bc2.ch/registration-info

💡 How can we harness functional homology & molecular similarity in protein and drug discovery, without falling into the pitfalls of data leakage?
Join this #BC2Basel workshop to explore practical strategies for robust, data-driven research

🔹Taught by Rebecca Buller (ZHAW), David Graber (ETH Zürich), Peter Stockinger (ZHAW)

📅 Mon 8 Sep at #bc2 👉Register: https://bc2.ch/registration-info

🚀 Interested in building and managing microbial genomic databases? Join the hands-on tutorial on Loculus & learn how to:
• set up and customize Loculus for lab or global use
• streamline data storage, preprocessing & analysis
• build your own prototype instance during the session

🔹 Taught by @chaoranchen & Anna Parker, from @ethzurich.bsky.social

📆 8 Sept, 9:00 - 16:15, at #bc2basel

👉 Register here: https://tinyurl.com/3y8ay2d6

@P_Palagi @valentynbez #BioinformaticsTraining

💡 Have you ever tried to combine symbolic & neural AI to tackle biomedical challenges? This tutorial will enable you to harness the power of biomedical knowledge graphs & LLM to support evidence-based discovery with concrete examples in antibiotic research & oncology.

🔹 Tutorial organized by Maxime Delmas and Andre Freitas, from the Idiap Research Institute, CH

📆 8 Sept, 13:00 - 16:15, at #bc2basel

👉 Register here: https://tinyurl.com/3y8ay2d6

@P_Palagi @valentynbez #BioinformaticsTraining

🎺 Hear ye, hear ye! Fellow students, biocurators, and early-career scientists: your chance to join the [BC]² Basel Computational Biology Conference 2025 is here!

Together with the ISB International Society for #biocuration, we offer 2️⃣ #travelgrants incl. free registration.

✅ Open to ISB members
✅ Priority to students, early-careers, and applicants from low/middle-income countries

👉 Submit by 30 April: https://www.bc2.ch/fellowships#isb

#bc2basel @genomic.socialgenomic.social

💡 Join our tutorial to explore the new Ensembl platform and Ensembl VEP (Variant Effect Predictor). Gain hands-on experience with the updated interface and learn to analyse and annotate various genomic data.

👉 Register here: https://tinyurl.com/3y8ay2d6

🔹 Workshop organized by Jorge Batista da Rocha, Louisse Mirabueno and Aleena Mushtaq (EMBL-EBI)

@P_Palagi @valentynbez
#Genomics #Ensembl #bc2basel #BioinformaticsTraining

💡 Join our tutorial to explore the new Ensembl platform and Ensembl VEP (Variant Effect Predictor). Gain hands-on experience with the updated interface and learn to analyse and annotate various genomic data.

👉 Register here: https://tinyurl.com/3y8ay2d6

🔹 Workshop organized by Jorge Batista da Rocha, Louisse Mirabueno and Aleena Mushtaq (EMBL-EBI)

@P_Palagi @valentynbez
#Genomics #Ensembl #bc2basel #BioinformaticsTraining

💡 Join our tutorial to explore the new Ensembl platform and Ensembl VEP (Variant Effect Predictor). Gain hands-on experience with the updated interface and learn to analyse and annotate various genomic data.

👉 Register here: https://tinyurl.com/3y8ay2d6

🔹 Workshop organized by Jorge Batista da Rocha, Louisse Mirabueno and Aleena Mushtaq (EMBL-EBI)

@P_Palagi @valentynbez
#Genomics #Ensembl #bc2basel #BioinformaticsTraining

💡 Join our tutorial to explore the new Ensembl platform and Ensembl VEP (Variant Effect Predictor). Gain hands-on experience with the updated interface and learn to analyse and annotate various genomic data.

👉 Register here: https://tinyurl.com/3y8ay2d6

🔹 Workshop organized by Jorge Batista da Rocha, Louisse Mirabueno and Aleena Mushtaq (EMBL-EBI)

@P_Palagi @valentynbez
#Genomics #Ensembl #bc2basel #BioinformaticsTraining

💡 Join our tutorial to explore the new Ensembl platform and Ensembl VEP (Variant Effect Predictor). Gain hands-on experience with the updated interface and learn to analyse and annotate various genomic data.

👉 Register here: https://tinyurl.com/3y8ay2d6

🔹 Workshop organized by Jorge Batista da Rocha, Louisse Mirabueno and Aleena Mushtaq (EMBL-EBI)

@P_Palagi @valentynbez
#Genomics #Ensembl #bc2basel #BioinformaticsTraining

#SIB Innovative Resource Award: Open Genome Browser by Thomas Roder, which allows to organize and visualize hundreds of bacterial genomes https://opengenomebrowser.bioinformatics.unibe.ch #bioinformatics #bc2basel