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#cartcells — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cartcells, aggregated by home.social.

  1. 📢 Just out: a Frontiers research topic on innovations in #CARTcells featuring 2 IMI projects, T2Evolve & ImSAVAR! Discover:
    ☑️ how AI can progress CAR-T cell research
    ☑️ how to advance CAR-T therapy in Europe
    ☑️ how to improve CAR-T cell safety engineering
    & more.
    👉 frontiersin.org/journals/immun

    #EU #Health #Innovation #Research #HorizonEU #Science #Cancer

  2. 📢 Just out: a Frontiers research topic on innovations in #CARTcells featuring 2 IMI projects, T2Evolve & ImSAVAR! Discover:
    ☑️ how AI can progress CAR-T cell research
    ☑️ how to advance CAR-T therapy in Europe
    ☑️ how to improve CAR-T cell safety engineering
    & more.
    👉 frontiersin.org/journals/immun

    #EU #Health #Innovation #Research #HorizonEU #Science #Cancer

  3. 📢 Just out: a Frontiers research topic on innovations in #CARTcells featuring 2 IMI projects, T2Evolve & ImSAVAR! Discover:
    ☑️ how AI can progress CAR-T cell research
    ☑️ how to advance CAR-T therapy in Europe
    ☑️ how to improve CAR-T cell safety engineering
    & more.
    👉 frontiersin.org/journals/immun

    #EU #Health #Innovation #Research #HorizonEU #Science #Cancer

  4. 📢 Just out: a Frontiers research topic on innovations in #CARTcells featuring 2 IMI projects, T2Evolve & ImSAVAR! Discover:
    ☑️ how AI can progress CAR-T cell research
    ☑️ how to advance CAR-T therapy in Europe
    ☑️ how to improve CAR-T cell safety engineering
    & more.
    👉 frontiersin.org/journals/immun

    #EU #Health #Innovation #Research #HorizonEU #Science #Cancer

  5. 📢 Just out: a Frontiers research topic on innovations in #CARTcells featuring 2 IMI projects, T2Evolve & ImSAVAR! Discover:
    ☑️ how AI can progress CAR-T cell research
    ☑️ how to advance CAR-T therapy in Europe
    ☑️ how to improve CAR-T cell safety engineering
    & more.
    👉 frontiersin.org/journals/immun

    #EU #Health #Innovation #Research #HorizonEU #Science #Cancer

  6. Last night, the inaugural Broermann Medical Innovation Award honored Dr. Carl June & Dr. Michel Sadelain for their pioneering work in CAR-T cell therapy.

    At the Hessian State Chancellery in Wiesbaden, the award was presented by Hessian Minister Boris Rhein.

    #cartcells #cancercure #awardceremony

  7. Scientists re-engineer a patient’s own T cells to target and destroy cancer cells

    Hodgkin lymphoma and other malignancies that express the CD30 protein have been the scourge of oncologists for decades.…
    #NewsBeep #News #Health #CA #Canada #cancer #CARTcells #GlobalGoodNews #healthnews #InnovationNews #Lymphoma #MedicalGoodNews #research #Science #t-cells #Technology
    newsbeep.com/ca/191330/

  8. Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain on receiving the 2025 Broermann Medical Innovation Award for the development of the CAR-T cell immunotherapy!

    Their work stands as a shining example of how research excellence can translate into real-world impact!

    #cancer #cartcells #research

  9. Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain on receiving the 2025 Broermann Medical Innovation Award for the development of the CAR-T cell immunotherapy!

    Their work stands as a shining example of how research excellence can translate into real-world impact!

    #cancer #cartcells #research

  10. Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain on receiving the 2025 Broermann Medical Innovation Award for the development of the CAR-T cell immunotherapy!

    Their work stands as a shining example of how research excellence can translate into real-world impact!

    #cancer #cartcells #research

  11. Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain on receiving the 2025 Broermann Medical Innovation Award for the development of the CAR-T cell immunotherapy!

    Their work stands as a shining example of how research excellence can translate into real-world impact!

    #cancer #cartcells #research

  12. Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain on receiving the 2025 Broermann Medical Innovation Award for the development of the CAR-T cell immunotherapy!

    Their work stands as a shining example of how research excellence can translate into real-world impact!

    #cancer #cartcells #research

  13. In München und Singapur werkelt das #Startup Eximmium an neuen Antikörpern gegen #Krebs – und macht sich dabei ein ungeklärtes Phänomen von Krebszellen zunutze. @InsertCaffeine erklärt uns das Ganze genauer: laborjournal.de/editorials/323 #Biotech #CarTCells #Antikörper

  14. In München und Singapur werkelt das #Startup Eximmium an neuen Antikörpern gegen #Krebs – und macht sich dabei ein ungeklärtes Phänomen von Krebszellen zunutze. @InsertCaffeine erklärt uns das Ganze genauer: laborjournal.de/editorials/323 #Biotech #CarTCells #Antikörper

  15. In München und Singapur werkelt das #Startup Eximmium an neuen Antikörpern gegen #Krebs – und macht sich dabei ein ungeklärtes Phänomen von Krebszellen zunutze. @InsertCaffeine erklärt uns das Ganze genauer: laborjournal.de/editorials/323 #Biotech #CarTCells #Antikörper

  16. In München und Singapur werkelt das #Startup Eximmium an neuen Antikörpern gegen #Krebs – und macht sich dabei ein ungeklärtes Phänomen von Krebszellen zunutze. @InsertCaffeine erklärt uns das Ganze genauer: laborjournal.de/editorials/323 #Biotech #CarTCells #Antikörper

  17. In München und Singapur werkelt das #Startup Eximmium an neuen Antikörpern gegen #Krebs – und macht sich dabei ein ungeklärtes Phänomen von Krebszellen zunutze. @InsertCaffeine erklärt uns das Ganze genauer: laborjournal.de/editorials/323 #Biotech #CarTCells #Antikörper

  18. 'A year ago, Caribou Biotherapeutics’ CEO was telling Fierce Biotech that the company’s natural killer (NK) cell therapy program was the “tip of the spear” for its solid tumor strategy and there were no plans to pause this work to conserve cash.
    Now, with the biotech eyeing up ways to keep the money flowing into 2026, the CRISPR-focused company has decided that the preclinical CAR-NK research needs to go—along with 12% of Caribou’s workforce'
    #Immunotherapy #Immunology #CARTcells
    fiercebiotech.com/biotech/cari

  19. 'A year ago, Caribou Biotherapeutics’ CEO was telling Fierce Biotech that the company’s natural killer (NK) cell therapy program was the “tip of the spear” for its solid tumor strategy and there were no plans to pause this work to conserve cash.
    Now, with the biotech eyeing up ways to keep the money flowing into 2026, the CRISPR-focused company has decided that the preclinical CAR-NK research needs to go—along with 12% of Caribou’s workforce'
    #Immunotherapy #Immunology #CARTcells
    fiercebiotech.com/biotech/cari

  20. 'A year ago, Caribou Biotherapeutics’ CEO was telling Fierce Biotech that the company’s natural killer (NK) cell therapy program was the “tip of the spear” for its solid tumor strategy and there were no plans to pause this work to conserve cash.
    Now, with the biotech eyeing up ways to keep the money flowing into 2026, the CRISPR-focused company has decided that the preclinical CAR-NK research needs to go—along with 12% of Caribou’s workforce'
    #Immunotherapy #Immunology #CARTcells
    fiercebiotech.com/biotech/cari

  21. 'A year ago, Caribou Biotherapeutics’ CEO was telling Fierce Biotech that the company’s natural killer (NK) cell therapy program was the “tip of the spear” for its solid tumor strategy and there were no plans to pause this work to conserve cash.
    Now, with the biotech eyeing up ways to keep the money flowing into 2026, the CRISPR-focused company has decided that the preclinical CAR-NK research needs to go—along with 12% of Caribou’s workforce'
    #Immunotherapy #Immunology #CARTcells
    fiercebiotech.com/biotech/cari

  22. 'Twenty-nine different Car-T treatments for autoimmune diseases, ranging from the muscle inflammation condition myositis to multiple sclerosis, are now being tested in clinical trials by drugmakers including Novartis and Bristol Myers Squibb'

    #Immunology #Autoimmunity #CARTcells

    ft.com/content/a974f4c1-bb8a-4

  23. 'Twenty-nine different Car-T treatments for autoimmune diseases, ranging from the muscle inflammation condition myositis to multiple sclerosis, are now being tested in clinical trials by drugmakers including Novartis and Bristol Myers Squibb'

    #Immunology #Autoimmunity #CARTcells

    ft.com/content/a974f4c1-bb8a-4

  24. 'Twenty-nine different Car-T treatments for autoimmune diseases, ranging from the muscle inflammation condition myositis to multiple sclerosis, are now being tested in clinical trials by drugmakers including Novartis and Bristol Myers Squibb'

    #Immunology #Autoimmunity #CARTcells

    ft.com/content/a974f4c1-bb8a-4

  25. 'Twenty-nine different Car-T treatments for autoimmune diseases, ranging from the muscle inflammation condition myositis to multiple sclerosis, are now being tested in clinical trials by drugmakers including Novartis and Bristol Myers Squibb'

    #Immunology #Autoimmunity #CARTcells

    ft.com/content/a974f4c1-bb8a-4

  26. 'These studies have helped to answer “some of the questions that were precipitated by the FDA announcement,” Maus said. They still have not found definitive evidence that CAR-T therapy has directly caused new cancers, she said, and scientists continue to suspect that such an event would be extremely rare.'
    #Immunology #Immunotherapy #CARTcells
    statnews.com/2024/07/12/cancer

  27. 'These studies have helped to answer “some of the questions that were precipitated by the FDA announcement,” Maus said. They still have not found definitive evidence that CAR-T therapy has directly caused new cancers, she said, and scientists continue to suspect that such an event would be extremely rare.'
    #Immunology #Immunotherapy #CARTcells
    statnews.com/2024/07/12/cancer

  28. 'These studies have helped to answer “some of the questions that were precipitated by the FDA announcement,” Maus said. They still have not found definitive evidence that CAR-T therapy has directly caused new cancers, she said, and scientists continue to suspect that such an event would be extremely rare.'
    #Immunology #Immunotherapy #CARTcells
    statnews.com/2024/07/12/cancer

  29. 'These studies have helped to answer “some of the questions that were precipitated by the FDA announcement,” Maus said. They still have not found definitive evidence that CAR-T therapy has directly caused new cancers, she said, and scientists continue to suspect that such an event would be extremely rare.'
    #Immunology #Immunotherapy #CARTcells
    statnews.com/2024/07/12/cancer

  30. 'Even without exposure to antigens, some CARs increase proliferation and nutrient uptake in T cells. Using stable isotope tracers and mass spectrometry, we observed basal metabolic fluxes through glycolysis doubling and amino acid uptake overtaking anaplerosis in CAR-T cells harbouring a rituximab scFv, unlike other similar anti-CD20 scFvs.'
    #Immunology #Immunotherapy #CARTcells
    nature.com/articles/s42255-024

  31. 'Even without exposure to antigens, some CARs increase proliferation and nutrient uptake in T cells. Using stable isotope tracers and mass spectrometry, we observed basal metabolic fluxes through glycolysis doubling and amino acid uptake overtaking anaplerosis in CAR-T cells harbouring a rituximab scFv, unlike other similar anti-CD20 scFvs.'
    #Immunology #Immunotherapy #CARTcells
    nature.com/articles/s42255-024

  32. 'Even without exposure to antigens, some CARs increase proliferation and nutrient uptake in T cells. Using stable isotope tracers and mass spectrometry, we observed basal metabolic fluxes through glycolysis doubling and amino acid uptake overtaking anaplerosis in CAR-T cells harbouring a rituximab scFv, unlike other similar anti-CD20 scFvs.'
    #Immunology #Immunotherapy #CARTcells
    nature.com/articles/s42255-024

  33. 'Even without exposure to antigens, some CARs increase proliferation and nutrient uptake in T cells. Using stable isotope tracers and mass spectrometry, we observed basal metabolic fluxes through glycolysis doubling and amino acid uptake overtaking anaplerosis in CAR-T cells harbouring a rituximab scFv, unlike other similar anti-CD20 scFvs.'
    #Immunology #Immunotherapy #CARTcells
    nature.com/articles/s42255-024

  34. 'However, the established use of viral vectors for genetic engineering of CAR immune cells is still subject to particular safety concerns and requires further improvements. 1 Consequently, non-viral methods for immune cell engineering are gaining increasing interest. In this context, transposon-based technologies represent a promising alternative engineering technology that enables safe genomic insertions of large cargo, such as multi-cistronic CAR-expression cassettes, using fast and cost-effective manufacturing processes '
    #Immunology #Immunotherapy #CARTcells
    cell.com/molecular-therapy-fam

  35. 'However, the established use of viral vectors for genetic engineering of CAR immune cells is still subject to particular safety concerns and requires further improvements. 1 Consequently, non-viral methods for immune cell engineering are gaining increasing interest. In this context, transposon-based technologies represent a promising alternative engineering technology that enables safe genomic insertions of large cargo, such as multi-cistronic CAR-expression cassettes, using fast and cost-effective manufacturing processes '
    #Immunology #Immunotherapy #CARTcells
    cell.com/molecular-therapy-fam

  36. 'However, the established use of viral vectors for genetic engineering of CAR immune cells is still subject to particular safety concerns and requires further improvements. 1 Consequently, non-viral methods for immune cell engineering are gaining increasing interest. In this context, transposon-based technologies represent a promising alternative engineering technology that enables safe genomic insertions of large cargo, such as multi-cistronic CAR-expression cassettes, using fast and cost-effective manufacturing processes '
    #Immunology #Immunotherapy #CARTcells
    cell.com/molecular-therapy-fam

  37. 'However, the established use of viral vectors for genetic engineering of CAR immune cells is still subject to particular safety concerns and requires further improvements. 1 Consequently, non-viral methods for immune cell engineering are gaining increasing interest. In this context, transposon-based technologies represent a promising alternative engineering technology that enables safe genomic insertions of large cargo, such as multi-cistronic CAR-expression cassettes, using fast and cost-effective manufacturing processes '
    #Immunology #Immunotherapy #CARTcells
    cell.com/molecular-therapy-fam

  38. " The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature
    in #monocytes and #Tcells of #SLE patients"

    insight.jci.org/articles/view/

    Striking that this apparently works better in getting rid of certain memory #Bcells than anti-CD20 antibodies.

    #scRNAseq #TCR #carTcells #OpenAccess #science

  39. " The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature
    in #monocytes and #Tcells of #SLE patients"

    insight.jci.org/articles/view/

    Striking that this apparently works better in getting rid of certain memory #Bcells than anti-CD20 antibodies.

    #scRNAseq #TCR #carTcells #OpenAccess #science

  40. " The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature
    in #monocytes and #Tcells of #SLE patients"

    insight.jci.org/articles/view/

    Striking that this apparently works better in getting rid of certain memory #Bcells than anti-CD20 antibodies.

    #scRNAseq #TCR #carTcells #OpenAccess #science