Live and recent posts from across the Fediverse tagged #tumour, aggregated by home.social.
Busy Philipps reveals rare brain tumour diagnosis and surgeries
Busy Philipps has opened up about one of the most frightening periods of her life, revealing that she was diagnosed with a rare malignant brain tumour earlier this year and underwent two surgeries during what she described as the “weirdest six months” of her l…
https://justpaste.in/news/busy-philipps-reveals-rare-brain-tumour-diagnosis-and-surgeries/
Mapping the gut bacteria linked to colorectal cancer | News | CORDIS
A large-scale analysis reveals a robust gut microbiome signature for colorectal cancer, paving the way for new dietary…
#Europe #EU #EuropeanCommission #CartoHostBug #colorectalcancer #gut #gutmicrobiome #lesion #microbialsignature #Microbiome #tumour
https://www.europesays.com/europe/122794/
I would lose my path netball commentating. Doctors found a tennis ball sized tumour on my brain – Jenny Woods
Initially he de…
#NewsBeep #News #Tennis #admittedly #AU #Australia #away #back #ball #Brain #commentating #could #doctors #each #explained #found #getting #hours #its #IVE #Jenny #long #looking #lose #my #netball #occurrences #older #on #path #plate #realise #sized #something #sports #there #took #tumour #were #What #wonder #woods #work #would #wrong
https://www.newsbeep.com/au/838262/
AstraZeneca wins EU tumour‑agnostic nod for Enhertu | AZN SEC Filing
FORM 6-K SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Report of Foreign Issuer Pursuant…
#EuropeSays #Britain #Europe #EU #AstraZeneca #antibodydrugconjugate #AZN #DaiichiSankyo #DESTINY-PanTumor02 #EnhertuEUapproval #Oncology #tumour-agnosticHER2therapy
https://www.europesays.com/britain/72846/
https://www.europesays.com/uk/873751/ Brit schoolboy’s horror as he wakes up paralysed shattering pro boxing dreams #Boxing #Hospitals #NHS #Sports #tumour #UK #UnitedKingdom
Brain tumour campaign for Bryan raises over £69k in 24 hours
A CAMPAIGN to raise £150,000 for well-known local figure Bryan Peterson’s brain tumour treatment has raised over £69,000…
#NewsBeep #News #Health #Brain #Bryan #GB #Peterson #research #tumour #UK #UnitedKingdom
https://www.newsbeep.com/uk/489852/
Scientists have developed a simple DNA blood test
that can predict how well patients with breast cancer will respond to treatment.
More than 2 million people globally each year are diagnosed with the disease,
which is the world’s most prevalent cancer.
Although treatments have improved in recent decades, it is not easy to know which ones will work best for which patients.
Now researchers have designed a #liquid #biopsy that tells doctors how likely a patient is to respond to a specific treatment -- even before it begins.
The test has the potential to be gamechanging because it means patients could be offered alternative options, and avoid treatments that won’t help them, boosting their chances of beating the disease.
The test, developed by a team at the Institute of Cancer Research, London (ICR),
analyses #circulating #tumour #DNA (ctDNA), which is released into the blood of patients by cancer cells.
Researchers measured these microscopic levels of cancer DNA in blood samples from 167 patients.
The test was trialled before treatment began and again four weeks later, after a single treatment cycle.
There was a strong association between low levels of ctDNA at the start of treatment, and treatment response, according to the team.
A similar association was seen with the results taken at four weeks.
https://www.theguardian.com/science/2026/jan/18/simple-blood-test-can-predict-which-breast-cancer-treatment-will-work-best-study-finds?CMP=Share_iOSApp_Other
https://www.europesays.com/uk/504903/ Scientists create cancer vaccine that could completely stop spread of disease #Cancer #Health #tumour #UK #UnitedKingdom
Swansea dad praises local opticians after life‑saving tumour diagnosis
Headaches led to urgent referral
Matthew Lewis, 47, a senior nurse at Morriston Hospital, had been suffering with persistent headaches when his wife noticed unusual changes in his behaviour last summer. Concerned, he booked an appointment at Specsavers Swansea in July 2024.
Optometrist Chinwendu Ojo carried out a comprehensive eye examination, including an optical coherence tomography (OCT) scan, which revealed a significant loss of vision in Mr Lewis’ left eye.
Within hours of being urgently referred to hospital, scans confirmed a glioblastoma – a fast‑growing cancerous brain tumour. He was transferred to the University Hospital of Wales in Cardiff for emergency neurosurgery, which doctors say saved his life.
“She didn’t just save his sight – she saved his life”
Following surgery, consultants told the family that without intervention, Mr Lewis may have had only weeks to live.
His wife, Kate Lewis, said:
“Because of Chinwendu’s thorough testing and immediate referral into hospital, we’ve been given so much more precious time together as a family – time we very nearly missed out on. Chinwendu didn’t just save Matthew’s sight; she saved his life. We will forever be grateful to her and the Specsavers Swansea team.”
Living life to the fullest
Since surgery, Mr Lewis has undergone intensive chemotherapy and radiotherapy. He remains positive and is currently cancer‑free, with regular scans every three months.
Doctors have explained that the cancer is likely to return, but the family are determined to make the most of every day.
Mrs Lewis added:
“It is extremely likely that Matthew’s cancer will return – it’s just a question of when, and how it can be treated when it does. We’re taking every day as it comes but concentrating on making as many special memories as possible. Over the past year, we’ve renewed our wedding vows, watched Matthew walk our daughter down the aisle, and enjoyed many holidays together as a family. We’re already planning our next trip.”
Importance of regular eye tests
Optometrist Chinwendu Ojo said the case highlights the importance of regular sight tests:
“Eye tests aren’t just about checking vision – they can reveal so much more about your overall health. That’s why it’s so important to have regular sight tests and seek professional advice if you notice unusual symptoms such as intense headaches or blurred vision. I’m so relieved we were able to pick up on Matthew’s vision loss and refer him quickly to ensure he got the urgent care he needed.”
Specsavers Swansea
Specsavers Swansea say they’re open seven days a week and also offer Home Visits service for those unable to leave their homes unaccompanied due to disability or illness.
Related articles
Llanelli-born Specsavers co-founder honoured with CBE
Doug Perkins recognised for services to business and healthcare after building Specsavers into a global brand.
Specsavers offers free eye and ear checks to people experiencing homelessness
Swansea opticians provide vital health services in partnership with Crisis.
Swansea opticians give back with donation to Crisis
Local Specsavers team support people at risk of homelessness with festive collection.
From ‘worst team’ to cup finalists: Cwm Albion’s turnaround
Swansea grassroots football side reach their first final in 26 years, backed by Specsavers’ Best Worst Team campaign.
#brainTumour #Cancer #Chemotherapy #eyeTest #glioblastoma #headaches #Optometrist #Radiotherapy #Specsavers #Swansea #tumour
Novel keyhole technique used to remove head tumour:
https://www.bbc.com/news/articles/c98yg1n9j83o
#medical #surgery #operation #tumour #cranium #medicine
"Researchers from RMIT University in Australia and Indian institutions unveiled a novel gold-based drug that shows significant promise in the fight against cancer. The drug has demonstrated the ability to slow #tumour growth while selectively targeting cancer cells more effectively than traditional #chemotherapy agents."
https://interestingengineering.com/health/gold-based-drug-slows-cancer
"By using time-resolved analyses of scRNA-seq data, we determined the potential transitional trajectories of tumor cells and identified the metastasis-initiating subpopulations"
https://link.springer.com/article/10.1007/s11684-024-1081-7
Reading right now. The identification of cells that initiate #metastasis are of interest, although n=2 paired primary and #BoneMarrow samples may be a bit limited.
Ania, National Cancer Institute, Kyiv, 2015
“Ania is a six-year-old girl who grew up in a small town outside the exclusion zone. People who grew up in the contaminated areas are having #children, and there’s a lot of genetic mutation and illness related to radiation. Ania was suffering from a malignant bone #tumour. She was a strong, positive child, passionate about art and drawing. The doctors told me she had little hope of survival. I don’t know if she is still alive or not.”
Fitness has always been a center-point of my life, a magnet which brought together the vastness of inner worlds and anchored them to the physical form. I could never desire a life without those abilities: climbing ice and rock, backcountry telemark, riding and racing, or simply exploring the beauty of nature.
Then, perhaps I pushed too hard for too long, or perhaps the multitude of medical experiments wasn't always a great idea. Nevertheless, I was doing what felt correct during those so very many years.
Here's a few photos from that last era, the months of 10% body fat, of deltoid striations and viciously vascular definition. Rowing crew for two to three hours per day, six days per week, boosted like a racehorse that never wants to stop.
Looking back with analytical eyes, as perhaps a more informed observer, now knowing the very same month which transpired these photos — was the very same month this brain decided a tumour should begin to grow. It never stopped growing, changing, affecting everything. The vascular muscles atrophied, resumed their softness, and body fat gradually doubled. No more race-pace, no more endorphins, no more no more.
That same month was the last time I rowed, the last time that magnet was able to hold it all together.
#fitness #gym #endorphins #physique #womenshealth #medical #existentialism #tumour #braaaains
Impressive new work by Moravec et al. in Nature Biotechnology, sadly not open source. "... a #HighThroughput personalized #TCR discovery pipeline ..." with which they "...identified dozens of CD4+ and CD8+ T-cell-derived TCRs with potent tumor reactivity, including TCRs that recognized patient-specific #neoantigens."
#Tasmaniandevil facial #tumour hasn’t let up https://cosmosmagazine.com/nature/animals/tasmanian-devil-facial-tumour-study/
In 2021, a study showed that 25 years of #DFTD’s spread had a massive impact on the Tasmanian devil population. The number of devils on the island of Tasmania shrank from 53,000 in 1996 to only 17,000 in 2021. The same study suggested that DFTD covered more than 90% of the devils’ range in Tasmania. As a result, #Australia’s largest remaining marsupial carnivore was listed as endangered.
Anyone who supports me to pay for services and assistance that are not covered by insurance in order to at least take away my financial worries while fighting my cancer can do so here:
My Amazon Wishlist:
https://www.amazon.de/hz/wishlist/ls/MLYVBXM60LR6?ref_=wl_share
My GoFoundMe Page:
https://gofund.me/bdc717c7
My Paypal Account:
https://www.paypal.com/pools/c/92opGMV4OB
Of course and that would be much more appreciate if you like and share my posts.
Thank you very much for any support.
Roland
Delighted that our #cancer #research has been selected for the cover image of December’s Life Science Alliance! In our article we show how gain of function mutations to the #ionchannel KCNQ3 may promote #tumour growth in oesophageal adenocarcinoma
A great read on #DrugResistance in #cancer, in Nature, by Vasan, Baselga, and Hyman. Sure, 2019 is four years ago, so there will be updates, e.g. on mapping #CancerDependency or the role of #ctDNA in early detection or monitoring. But the framework for understanding drug resistance is here.
https://www.nature.com/articles/s41586-019-1730-1
Although it doesn't say it, I think it may be #OpenAccess since I'm not logged in to my institution right now but can reach full text anyway.
Come and work with us - job opening at the Molenaar research group in the Princess Máxima Center for pediatric oncology, looking for a #bioinformatician / #DataScientist.
Together with my colleagues and me you will research #neuroblastoma, with a focus on #tumour #microenvironment and the #immune compartment using a range of #sequencing data and other high-throughput data.
#CancerResearch #scRNAseq
#FediJobs #JobOffer
For further information, see the vacancy below:
https://werkenbijprinsesmaximacentrum.nl/en/vacancy/bioinformatics-research-scientist/
My #Information #List is getting heavyweight! So much random factiness my Solo Synthesist is going crazy following leads that appeal to me.
I'm in danger of my head blowing up far sooner than my #Brain #Tumour escaping control!! 😂 😎
It's wonder-filled this place, a trove of treasures!
"Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma"
Nice new work based on #scRNAseq from our Drost group colleagues at the #PrincessMaximaCenter. a.o., a potential role of #NECTIN3 and #TIGIT in #tumour-induced T cell dysfunction.
https://www.nature.com/articles/s41467-023-38886-8
Meet Valentina Zuco, first author of a new paper from Nadia Zaffaroni @IstTumori & colleagues that demonstrated the efficacy of new drug combination for desmoplastic small round cell #tumour in #PatientDerivedXenograft
Interview & research article below:
👩🏼🔬https://journals.biologists.com/dmm/article/16/6/dmm050313/316732/
📰https://journals.biologists.com/dmm/article/16/6/dmm049649/316733/
"These data identify developmental lineage as a key determinant of sensitivity to anti-GD2 based immunotherapies and credential #EZH2 inhibitors for clinical testing in combination with anti-GD2 antibody to enhance outcomes for children with #neuroblastoma".
An article that I had missed, by Mabe et al., linking #mesenchymal #tumour cell state, #GD2 expression, #ST8SIA1 expression, and #immunotherapy #TherapyResistance.
https://www.nature.com/articles/s43018-022-00405-x
Sadly, not open access.
Well there was always 30% change my tumour would come back and it has as the lesions on my liver are the return of my Tumour.
I did not see the Oncologist today but a Consultant who told me what would happen next which will be a PET CT Scan possibility followed by surgery to remove the tumours off my liver.
So it all start again but at least this time I know what I am in for and like last time it has not hit me yet but I will survive it again.
That session was concluded by Caroline Hochheuser showing our own #scRNAseq work, comparing primary #tumour to bone marrow #metastasis from the same patients. 🤩
Yesterday, in the afternoon plenty of #scRNAseq work, a.o. Céline Delloye-Bourgeois showing her group's latest work on #neuroblastoma development and #metastatic progression. Including some of our own scRNA-seq data. Very cool.
Furthermore, more #SingleCell, also spatial, sequencing on #tumour heterogeneity and early stages. And work on cells that persist during/after #therapy, dubbed persister cells.
An impressive keynote lecture by Chris Marine on #melanoma and the role of the #tumour #microenvironment, and MES-like cells in #metastasis and #drug #resistance.
https://www.nature.com/articles/s41586-023-06036-1
"The degree of functional connectivity between #glioblastoma and the normal #brain negatively affects both patient survival and performance in language tasks. These data demonstrate that high-grade gliomas functionally remodel #neural circuits in the #human brain, which both promotes #tumour progression and impairs #cognition."
Real cool stuff from the group of @robjohnnoble :
"Warlock: an automated computational workflow for simulating spatially structured #tumour #evolution"
Treating #Cancer Through Restoring Function of #Tumour Suppressor Using #Vegetable Extract | Study in mice and human cells describes reactivation of an important tumour suppressive #gene using a vegetable extract thus offering a promising strategy for...
