#biopsy — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #biopsy, aggregated by home.social.
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Neurosurgical #Biopsy and #Resection for #Diagnosis and #Treatment of #Balamuthia mandrillaris Amebic #Encephalitis, #USA, https://etidiohnew.blogspot.com/2026/06/neurosurgical-biopsy-and-resection-for.html
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Neurosurgical #Biopsy and #Resection for #Diagnosis and #Treatment of #Balamuthia mandrillaris Amebic #Encephalitis, #USA, https://etidiohnew.blogspot.com/2026/06/neurosurgical-biopsy-and-resection-for.html
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🔬 Biopsy smart, not routine.
Knowing when to biopsy—and when not to— can change diagnosis, management, and outcomes in upper GI endoscopy.
From Barrett’s protocols to linitis plastica sampling—precision matters.
#GastroAGI #Endoscopy #UpperGI #Biopsy #Gastroenterology #GIEndoscopy #MedicalEducation
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Puncture - biopsy of kidney tissue #puncture #kidneyhealth #kidneydisease #biopsy ... Continue to: https://www.facebook.com/reel/786051534496452/
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Scientists have developed a simple DNA blood test
that can predict how well patients with breast cancer will respond to treatment.More than 2 million people globally each year are diagnosed with the disease,
which is the world’s most prevalent cancer.
Although treatments have improved in recent decades, it is not easy to know which ones will work best for which patients.
Now researchers have designed a #liquid #biopsy that tells doctors how likely a patient is to respond to a specific treatment -- even before it begins.The test has the potential to be gamechanging because it means patients could be offered alternative options, and avoid treatments that won’t help them, boosting their chances of beating the disease.
The test, developed by a team at the Institute of Cancer Research, London (ICR),
analyses #circulating #tumour #DNA (ctDNA), which is released into the blood of patients by cancer cells.
Researchers measured these microscopic levels of cancer DNA in blood samples from 167 patients.
The test was trialled before treatment began and again four weeks later, after a single treatment cycle.
There was a strong association between low levels of ctDNA at the start of treatment, and treatment response, according to the team.
A similar association was seen with the results taken at four weeks.
https://www.theguardian.com/science/2026/jan/18/simple-blood-test-can-predict-which-breast-cancer-treatment-will-work-best-study-finds?CMP=Share_iOSApp_Other -
Scientists have developed a simple DNA blood test
that can predict how well patients with breast cancer will respond to treatment.More than 2 million people globally each year are diagnosed with the disease,
which is the world’s most prevalent cancer.
Although treatments have improved in recent decades, it is not easy to know which ones will work best for which patients.
Now researchers have designed a #liquid #biopsy that tells doctors how likely a patient is to respond to a specific treatment -- even before it begins.The test has the potential to be gamechanging because it means patients could be offered alternative options, and avoid treatments that won’t help them, boosting their chances of beating the disease.
The test, developed by a team at the Institute of Cancer Research, London (ICR),
analyses #circulating #tumour #DNA (ctDNA), which is released into the blood of patients by cancer cells.
Researchers measured these microscopic levels of cancer DNA in blood samples from 167 patients.
The test was trialled before treatment began and again four weeks later, after a single treatment cycle.
There was a strong association between low levels of ctDNA at the start of treatment, and treatment response, according to the team.
A similar association was seen with the results taken at four weeks.
https://www.theguardian.com/science/2026/jan/18/simple-blood-test-can-predict-which-breast-cancer-treatment-will-work-best-study-finds?CMP=Share_iOSApp_Other -
https://www.europesays.com/ie/212333/ The future of cancer detection could be just a blood test away, say scientists #ArtificialIntelligence #biopsy #blood #BloodTest #BodyFluids #cancer #CancerDiagnostics #Cell #Diagnostics #Éire #Exosomes #Genetic #Health #IE #Ireland #Lipids #Metabolites #Research #Tumor #UrineTest
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Elderly neighbor had a cool biopsy of a lung. They use a little robot coming in through the airways. The robot picked up some tissue and dropped off a couple of tiny pieces of metal.
They call these "targets". They allow superior targeting of tumors for radiation treatment.
No, they don't go pick them up again if the biopsy comes back negative, 🙂.
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Elderly neighbor had a cool biopsy of a lung. They use a little robot coming in through the airways. The robot picked up some tissue and dropped off a couple of tiny pieces of metal.
They call these "targets". They allow superior targeting of tumors for radiation treatment.
No, they don't go pick them up again if the biopsy comes back negative, 🙂.
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With the start of new testing for Cancer's return, "It's All Coming Back to Men Now" in an unpleasant manor. #memories
#cancer #cancerfight #biopsy #cystoscopy #therapy #unansweredquestions #meditation #spookyseason #mentalhealth #BreastCancerAwarenessMonth #writer #writerscommunity #lovemeanywayshttps://rickollie.com/2025/10/04/cancer-follow-up-with-urology-its-all-coming-back-to-me-now/
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In a weeklong journey leading up to my second cancer biopsy, I give my thoughts on what's happening with humor, love and truth.
#cancer #therapy #biopsy #friendships #Voodoo #Love #Chrisrmas #writerscommunity #healthmatters #lovemeanyways #understandingcancer #thefightisreal #gotlove #writer #healthhttps://rickollie.com/2025/09/19/my-second-cancer-biopsy-a-week-in-the-life/
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In a weeklong journey leading up to my second cancer biopsy, I give my thoughts on what's happening with humor, love and truth.
#cancer #therapy #biopsy #friendships #Voodoo #Love #Chrisrmas #writerscommunity #healthmatters #lovemeanyways #understandingcancer #thefightisreal #gotlove #writer #healthhttps://rickollie.com/2025/09/19/my-second-cancer-biopsy-a-week-in-the-life/
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In a weeklong journey leading up to my second cancer biopsy, I give my thoughts on what's happening with humor, love and truth.
#cancer #therapy #biopsy #friendships #Voodoo #Love #Chrisrmas #writerscommunity #healthmatters #lovemeanyways #understandingcancer #thefightisreal #gotlove #writer #healthhttps://rickollie.com/2025/09/19/my-second-cancer-biopsy-a-week-in-the-life/
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What is bone marrow biopsy?
A bone marrow biopsy consists of taking a sample of the bone and analyzing it under a microscope after it has been fixed and stained.
The study is slightly painful and is done under local anesthesia.
A bone marrow biopsy allows you to check myelogram data for such diagnoses: bone marrow aplasia, the presence of cells in the bone marrow that are absent under normal conditions (leukemia). -
DATE: May 21, 2025 at 08:30AM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@galvanizetx #Aliya could enable one-step tumor #biopsy and #ablation
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: May 21, 2025 at 08:30AM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@galvanizetx #Aliya could enable one-step tumor #biopsy and #ablation
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: May 20, 2025 at 06:30PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@galvanizetx #Aliya could enable one-step tumor #biopsy and #ablation
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: May 20, 2025 at 06:30PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@galvanizetx #Aliya could enable one-step tumor #biopsy and #ablation
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: April 25, 2025 at 06:00PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@Mursla #Evoliver #biopsy #bloodtest granted breakthrough designation
#medtech @FDADeviceInfo
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Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: April 25, 2025 at 06:00PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@Mursla #Evoliver #biopsy #bloodtest granted breakthrough designation
#medtech @FDADeviceInfo
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: August 19, 2024 at 07:30AM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
Dermr could displace skin biopsies with microneedle patch
#medtech #dermr #skincancer #biopsy
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: August 19, 2024 at 07:30AM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
Dermr could displace skin biopsies with microneedle patch
#medtech #dermr #skincancer #biopsy
Here are any URLs found in the article text:
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: August 16, 2024 at 04:30PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
Dermr could displace skin biopsies with microneedle patch
#medtech #dermr #skincancer #biopsy
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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DATE: August 16, 2024 at 04:30PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
Dermr could displace skin biopsies with microneedle patch
#medtech #dermr #skincancer #biopsy
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
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-------------------------------------------------#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech
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Actually getting to enjoy some vacation time this summer. Son and Hubby are already off in China for July. I’ll be heading out for a couple weeks on a cruise to Northern Europe and Scandinavia. So exiting!
Less exciting was two weeks of nasty GI upset and learning I have a “nodule” on my right adrenal gland. Still a biopsy away from understanding more about it.
Thankfully I’m feeling better and trip WILL happen.
#cruise #trabel #vacation #tunor #CTScan #Ultrasound #biopsy
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Actually getting to enjoy some vacation time this summer. Son and Hubby are already off in China for July. I’ll be heading out for a couple weeks on a cruise to Northern Europe and Scandinavia. So exiting!
Less exciting was two weeks of nasty GI upset and learning I have a “nodule” on my right adrenal gland. Still a biopsy away from understanding more about it.
Thankfully I’m feeling better and trip WILL happen.
#cruise #trabel #vacation #tunor #CTScan #Ultrasound #biopsy
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#Parkinsons Can Now Be Detected Through the Skin. New test identifies Parkinson’s by a protein rather than waiting for symptoms that can take years to appear https://www.msn.com/en-us/health/other/parkinson-s-disease-can-now-be-detected-through-the-skin/ar-BB1kecIH #healthcare #skin #biopsy #abnormal #protein #neurodegenerative
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#Parkinsons Can Now Be Detected Through the Skin. New test identifies Parkinson’s by a protein rather than waiting for symptoms that can take years to appear https://www.msn.com/en-us/health/other/parkinson-s-disease-can-now-be-detected-through-the-skin/ar-BB1kecIH #healthcare #skin #biopsy #abnormal #protein #neurodegenerative
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Welcome to #chronicillness Giorgia Lupi NYT: 1,374 Days: My Life w #LongCovid. "In the past 3yrs, I have experienced, tracked more than 21 symptoms, consolidated here in2 13 colored categories. Seen 46 drs at 233 drs appointments. Had my #blood drawn 59 times. Done 12 #Xrays, 15 #MRI, 4 #CT scans, one #PET scan, a #tilttable test, an #electromyogram, a skin #biopsy, a #carotid #ultrasound, #microclot and #neuroinflammation tests, Been to the emergency room 6x Read Free https://www.nytimes.com/interactive/2023/12/14/opinion/my-life-with-long-covid.html?unlocked_article_code=1.F00.435C.ojkN6YhWx43Q
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Welcome to #chronicillness Giorgia Lupi NYT: 1,374 Days: My Life w #LongCovid. "In the past 3yrs, I have experienced, tracked more than 21 symptoms, consolidated here in2 13 colored categories. Seen 46 drs at 233 drs appointments. Had my #blood drawn 59 times. Done 12 #Xrays, 15 #MRI, 4 #CT scans, one #PET scan, a #tilttable test, an #electromyogram, a skin #biopsy, a #carotid #ultrasound, #microclot and #neuroinflammation tests, Been to the emergency room 6x Read Free https://www.nytimes.com/interactive/2023/12/14/opinion/my-life-with-long-covid.html?unlocked_article_code=1.F00.435C.ojkN6YhWx43Q
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Bathing while attempting to keep a foot wound dry is quite exhausting.
If anyone needs me, I’ll be convalescing on the couch.
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Bathing while attempting to keep a foot wound dry is quite exhausting.
If anyone needs me, I’ll be convalescing on the couch.
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Just Published!
Interventional Oncology Techniques: A Primer for Non-users
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Just Published!
Interventional Oncology Techniques: A Primer for Non-users
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Heading out to the #bonemarrow #biopsy today
I'm terrified what I'll toot after the drugs kick in
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https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00021-1
"The key biological features of tumor progression are influenced by the circadian rhythm.
The timing of biopsy collection can be crucial for accurate cancer diagnosis.
The metastatic spread of breast cancer occurs predominantly during the rest phase.
Chronotherapy could lead to more effective disease management in cancer patients."
#reviewPaper #circadianRhythm #metastasis #biopsy #chronotherapy #cancer #diagnosis #treatment
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Tim Salditt (http://twitter.com/SaldittLab, substituting Jasper Frohn): #Multiscale #Xray Phase Contrast #Tomography at #GINIX/P10: Concepts, Implementation and Applications
- fantastic collaboration with the P10 team
- directly comparing #STED to #Minflux; old #confocal? not worth mentioning 😂
- overview tomo, then zoom-in
- tumorous human pancreatic tissue #biopsy: quantify the #tumor type
- from electron density to metrics, quantify fibres etc.
- #hippocampus patho punch, #Alzheimer sample -
Tim Salditt (http://twitter.com/SaldittLab, substituting Jasper Frohn): #Multiscale #Xray Phase Contrast #Tomography at #GINIX/P10: Concepts, Implementation and Applications
- fantastic collaboration with the P10 team
- directly comparing #STED to #Minflux; old #confocal? not worth mentioning 😂
- overview tomo, then zoom-in
- tumorous human pancreatic tissue #biopsy: quantify the #tumor type
- from electron density to metrics, quantify fibres etc.
- #hippocampus patho punch, #Alzheimer sample -
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The Uprising of Mitochondrial DNA Biomarker in Cancer
Advances in predictive #diagnostic and #precisionmedicine, can lead to powerful discoveries and treatments for patients. #Cancer cells acquire functional capabilities to survive, proliferate, and circulate due to an enabling characteristic called genomic instability. Genomic maintenance systems have the ability to spot and repair any #DNA defects, while cancer cells increase the rates of mutation that orchestrate tumorigenesis. Chromosomal instability (CIN) is one of the most frequent changes observed in cancer cells, which often results from aberrations in chromosome structures and numbers. The second section of the paper focuses on #biomarkers, which are substances, structures, or processes that can influence or predict the incidence and outcome of a disease. There are three classifications of biomarkers: exposure, effect, and susceptibility. Biomarkers of exposure measure exogenous chemicals or their metabolites within an organism, while biomarkers of effect measure alterations of endogenous factors caused by exposure to an exogenous agent. Biomarkers of susceptibility measure genetic polymorphism predisposition of individuals and their external multifactorial influencers. Surrogate endpoints are often used to substitute clinical endpoints, and biomarkers can be used as a screening tool for an early indicator of #malignancy-risk development. They can also be used as diagnostic aids and prognostic biomarkers, as well as predictive biomarkers to identify the sensitivity and/or resistance of cancer patients towards specific agents or #medical product exposure.
The communication between the nucleus and mitochondria of a cell is known as intergenomic #crosstalk and it is bidirectional, meaning it can go both ways. It is important for regulating energy metabolism and tumor suppression. The communication is achieved by pathways such as anterograde #signaling and retrograde signaling. Anterograde signaling is when the nucleus controls gene transcription and cytoplasmic mRNA translation in response to external signals. Retrograde signaling is when mitochondrial dysfunction or loss of mitochondrial #membrane potential triggers communication with the nuclear genetic compartment. This communication is important for #homeostasis adaptation and can detect any nuclear damage or nuclear stress.
#Mitochondria are organelles found in cells that are responsible for producing energy. They are believed to have originated from a #singlecell-ed organism and are made up of two membranes. They contain their own genetic material, called #mtDNA, which is made up of 16569 nucleotide base pairs. mtDNA mutations can lead to mitochondrial dysfunction, which can cause #onco-genic events, such as #tumor cell reprogramming and metabolic shifts. #Mitoepigenetics is the study of how #epigenetics mechanisms regulate mtDNA transcription and replication, and it is believed to be involved in cancer progression.
The interconnection between #carcinogenesis (the development of cancer) and mitochondria (the energy-producing organelles in cells) was first proposed in 1973. Since then, there have been many studies done on this topic, using DNA scanning technologies to detect mutations and deletions. Mitochondrial DNA (mtDNA) is beneficial for carcinogenic studies because it consists of 37 genes with no introns, meaning most mutations will occur in coding regions. Additionally, mtDNA has a small size, is easy to extract, has no genetic rearrangements, and has fast mutation rates, which makes it useful for molecular research. It also has a high copy number, meaning only minimal #tissue samples are needed for analysis. Large-scale deletions are commonly known to be responsible for mitochondrial diseases, and are thought to be the cause of various diseases and cancers.
Two types of mtDNA deletions, 3.4 kb and 4977 bp are associated with various types of cancer. The 3.4 kb deletion was patented by Parr et al. [97] and is used to detect cancer in individuals. It is also used to determine different #prostate tissue types, either benign, malignant, or proximal to malignant [100]. The 4977 bp deletion is primarily associated with #aging and is a common deletion with missing mtDNA nucleotide sequences starting at 8470 to 13447 np [106]. It has been studied in various types of cancer, such as #breastcancer, #colorectal, gastric, hepatocellular, and #brain tumors, and is thought to be associated with external environmental factors, genetic predisposition, and ethnicity.
The text is discussing different types of deletions in mtDNA (mitochondrial DNA) that are associated with cancer. The 5.1.3 section is talking about the 3895 bp deletion, which was first observed in 1991 in two patients with progressive external #ophthalmoplegia. It was then found to be 10 times less frequent than the 4977 bp deletion. A study involving 104 age-matched subjects showed that the 3895 bp deletion was more frequent in those with usually sun-exposed skin and nonmelanoma skin cancer. The 4576 bp deletion was then discussed, which was found to be an indicator for breast cancer in a study involving 39 breast cancer patients. The 4576 bp deletion was not found in 23 normal patients without breast cancer. The text then moves on to discuss mtDNA copy number, which is the amount of mtDNA in each cell. It is suggested that mtDNA copy number changes may lead to mitochondrial instability and regulate energy metabolism, which can initiate #tumorigenesis. Studies have also shown that mtDNA copy number changes can be used as a predictive biomarker for #chemotherapy response.
Cell-free mtDNA (cf-mtDNA) is a type of mitochondrial DNA that is released into the #blood circulation due to disruption of the normal mitochondrial life cycle. It is believed to activate the Toll-like receptor 9 (TLR9) pathway, which can cause #inflammation and potentially lead to cancer. It has been used to diagnose cancer and sepsis, and as a biomarker for metabolic syndrome and predicting the risk of future diabetes. It is also being studied as a #noninvasive liquid #biopsy for cancer, as higher levels of cf-mtDNA have been found in cancer patients compared to healthy controls. Research is being conducted to find the potential link between cf-mtDNA and various cancers, as it is a preferable biomarker due to its higher mtDNA copy number, simpler structure, and shorter length.
Mitochondrial Microsatellite Instability (#mtMSI) is a type of genetic mutation that occurs in the mitochondrial genome. It is caused by short tandem repeats (mononucleotide or dinucleotide) of 1 to 6 base pairs that are scattered throughout the mitochondrial genome. These variations can lead to frameshift mutations, which can be caused by DNA polymerase γ, an enzyme that is responsible for oxidative damage. Mammalian mitochondria also have an inefficient mismatch repair system, which can lead to mtMSI formation. The most commonly reported mtMSI is located in the D-loop region, which is a mutational hotspot in primary tumors. It is a highly polymorphic homopolymeric C stretch, which is involved in R-loop formation, a stable RNA-DNA hybrid that triggers mtDNA replication. D310 alteration has been suggested as a new cancer detection tool and a potential early premalignant cancer marker. Another potential marker is D16184, which is located in the hypervariable region I and is involved in mtDNA biogenesis. Studies have reported the presence of D16184 in various cancer types, such as gastric and endometrial carcinoma. Somatic mtDNA alterations have also been correlated to cancer, with evidence showing that mtDNA changes can contribute to the development or progression of cancer. One example of a somatic mtDNA alteration is A12308G, which is located in the variable loop next to the anticodon stem of tRNA Leu (CUN). This alteration has been suggested as a potential diagnostic tool for #colorectalcancer and as a risk factor for prostate and #renalcancer. A10398G has also been studied in relation to cancer, although the results have been conflicting.
Mitochondrial biomarkers are molecules that can be used to detect cancer in its early stages. A commercial kit (PCMT) has been developed to help with this detection. However, even if cancer is detected early, it can still be difficult to treat if the symptoms have not yet developed. Therefore, researchers are looking into gene therapy and other mitochondrial interventions as potential treatments for cancer. They can use current advancements in vitro mitochondrial intervention to identify the pathogenicity and therapeutic potential of a particular mtDNA mutation. One method proposed is to transfer artificial healthy mitochondria to remove damaged mtDNA without genetic manipulation. Other studies have looked at the levels of mtDNA biomarkers in cancerous and non-cancerous samples, as well as the levels of mtDNA methylation and mtRNA in cancerous tissues.
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So yesterday I had a #biopsy done. (Ya it’s been a fun week! 🎉) And for the first time I put down that I was #autistic on the paperwork. And I let the dr know that I feel pain a little more intensely. Again I’m “black and white” about this sensory issue too. I either ignore pain really well..don’t feel it..or I REALLY feel it. No middle way for this gal. I’ve never done this before..speaking up about it. I was nervous but I was like..it’s okay to say something now. It’s okay now. Wow, huh? 🥹
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OK, so the biopsies were positive for Adenocarcinoma. It's Stage 2, which from what I can tell means it's confined for now. More referrals, surgery, et cetera.
I think I am not processing fully right now. But all beams, prayers, positive thoughts welcome. :mindlyheart:
