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#sequencing — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #sequencing, aggregated by home.social.

  1. After more than two weeks, the Grauniad now has an #obituary for #CraigVenter: theguardian.com/science/2026/m I was kind of surprised that he died at a normal age, rather than using his resources to engineer his own immortality.

    #science #genome #DNA #sequencing #humanGenome

  2. After more than two weeks, the Grauniad now has an #obituary for #CraigVenter: theguardian.com/science/2026/m I was kind of surprised that he died at a normal age, rather than using his resources to engineer his own immortality.

    #science #genome #DNA #sequencing #humanGenome

  3. After more than two weeks, the Grauniad now has an #obituary for #CraigVenter: theguardian.com/science/2026/m I was kind of surprised that he died at a normal age, rather than using his resources to engineer his own immortality.

    #science #genome #DNA #sequencing #humanGenome

  4. After more than two weeks, the Grauniad now has an #obituary for #CraigVenter: theguardian.com/science/2026/m I was kind of surprised that he died at a normal age, rather than using his resources to engineer his own immortality.

    #science #genome #DNA #sequencing #humanGenome

  5. After more than two weeks, the Grauniad now has an #obituary for #CraigVenter: theguardian.com/science/2026/m I was kind of surprised that he died at a normal age, rather than using his resources to engineer his own immortality.

    #science #genome #DNA #sequencing #humanGenome

  6. Speaking of - anyone know if there's any documentation/literature on how ONT put together their bacterial dorado polishing model?

    I know it fares well in benchmarks, but curious about non-bacterial prokaryotes. Is anyone putting together their own polishing models for test?

    #bioinformatics #sequencing #ONT

  7. Speaking of - anyone know if there's any documentation/literature on how ONT put together their bacterial dorado polishing model?

    I know it fares well in benchmarks, but curious about non-bacterial prokaryotes. Is anyone putting together their own polishing models for test?

    #bioinformatics #sequencing #ONT

  8. Speaking of - anyone know if there's any documentation/literature on how ONT put together their bacterial dorado polishing model?

    I know it fares well in benchmarks, but curious about non-bacterial prokaryotes. Is anyone putting together their own polishing models for test?

    #bioinformatics #sequencing #ONT

  9. Speaking of - anyone know if there's any documentation/literature on how ONT put together their bacterial dorado polishing model?

    I know it fares well in benchmarks, but curious about non-bacterial prokaryotes. Is anyone putting together their own polishing models for test?

    #bioinformatics #sequencing #ONT

  10. Speaking of - anyone know if there's any documentation/literature on how ONT put together their bacterial dorado polishing model?

    I know it fares well in benchmarks, but curious about non-bacterial prokaryotes. Is anyone putting together their own polishing models for test?

    #bioinformatics #sequencing #ONT

  11. Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
    nature.com/articles/s41587-026

    everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
    to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
    neat!

  12. Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
    nature.com/articles/s41587-026

    everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
    to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
    neat!

  13. Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
    nature.com/articles/s41587-026

    everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
    to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
    neat!

  14. Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
    nature.com/articles/s41587-026

    everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
    to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
    neat!

  15. Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
    nature.com/articles/s41587-026

    everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
    to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
    neat!

  16. 'Data Thinning for Convolution-Closed Distributions', by Anna Neufeld, Ameer Dharamshi, Lucy L. Gao, Daniela Witten.

    jmlr.org/papers/v25/23-0446.ht

    #thinning #rna #sequencing

  17. 'Data Thinning for Convolution-Closed Distributions', by Anna Neufeld, Ameer Dharamshi, Lucy L. Gao, Daniela Witten.

    jmlr.org/papers/v25/23-0446.ht

    #thinning #rna #sequencing

  18. 'Data Thinning for Convolution-Closed Distributions', by Anna Neufeld, Ameer Dharamshi, Lucy L. Gao, Daniela Witten.

    jmlr.org/papers/v25/23-0446.ht

    #thinning #rna #sequencing

  19. 'Data Thinning for Convolution-Closed Distributions', by Anna Neufeld, Ameer Dharamshi, Lucy L. Gao, Daniela Witten.

    jmlr.org/papers/v25/23-0446.ht

    #thinning #rna #sequencing

  20. 'Data Thinning for Convolution-Closed Distributions', by Anna Neufeld, Ameer Dharamshi, Lucy L. Gao, Daniela Witten.

    jmlr.org/papers/v25/23-0446.ht

    #thinning #rna #sequencing

  21. Any #archaea lab out there interested in having their Natrialba species sequenced on ONT r10 up to about 3Kx read depth for free? I'll send back annotated assembly, methylation data and raw signal files. I need at least one more species for a paper from a particular phylogenetic clade within the genus.

    Please feel free to DM & boost!

    #microbiology #collaboration #sequencing #bioinformatics

  22. Minimod preprint from @hasindu2008 gang is out. Code available github.com/warp9seq/minimod

    I love the work they're doing with slow5/blow5 open spec for ONT raw data, and archive all internal reads using them. Really need to sit down and test this one out with my #archaea raw data!

    #bioinformatics #methylation #ONT #sequencing

  23. Does anyone have experience with the new ultima genome sequencing technology? Does it compare well to illumina?

    It is apparently cheaper , but I was not sure about the quality.

    #genomics #sequencing #omics #illumina

  24. I have a big microbial sequencing batch coming up that will require decent methylation calling.

    How's ONT vs PacBio on this front? R10's direct methylation detection is exactly what I'm looking for, but curious about first-hand experience from researchers for both platforms.

    #sequencing #bioinformatics #nanopore #pacbio

  25. Updated our P2 output summary!

    Across runs, output per flow cell varies widely, but the average is landing at ~80 Gbp.

    Big thanks to Julie for the sequencing effort.

    More info: izmb.uni-bonn.de/en/pbb/news#P

    #Genomics #Sequencing #P2 #ResearchUpdate
    @boas_pucker

  26. Our digital Christmas tree this year is built from squares inspired by performance indicators in our ONT sequencing experiments 🎄📊
    In 2025, sequencing output increased substantially — a great way to close the year!

    More on the design idea and other news:
    izmb.uni-bonn.de/en/pbb/news#t

    #OpenScience #Sequencing #DataArt #Christmas #LabLife
    @boas_pucker
    @samnm