#chembio — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #chembio, aggregated by home.social.
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Jon Stokes gave an inspiring and highly interactive @LED3hub Lecture. He talked about the power and the limitations of AI for antibiotic drug discovery. (1/4)
#Chemistry #ChemBio #DrugDiscovery #Antibiotics #AI #MachineLearning
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We are very happy that Jon Stokes from McMaster University visited us today for a LED3 Lecture. He gave "An honest discussion about AI for antibiotic discovery".
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Interesting paper by the groups of Jongmin Park, Juyong Lee and Hankum Park in Nature Communications. They developed muscle-specific PROTACs engaging the E3 ligase KLHL41. Great to see the most potent molecules with covalent KLHL41 ligands.
https://www.nature.com/articles/s41467-026-73252-4
#Chemistry #ChemBio #TPD -
The first @LED3hub Business Club is off to a great start with an inspiring lecture by Rogier Buijsman, CEO of Crossfire Oncology. He talked about his journey of setting up a biotech company and gave important tips for the next generation of founders.
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The first @LED3hub Business Club is off to a great start with an inspiring lecture by Rogier Buijsman, CEO of Crossfire Oncology. He talked about his journey of setting up a biotech company and gave important tips for the next generation of founders.
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RE: https://mstdn.science/@GDCh_BioChem/116594285990119910
A great opportunity to nominate PhD candidates for the #YoungScientistAward of @GDCh_BioChem! Self-nominations are also possible!
#Academia #Biochemistry #ChemBio #Chemistry #Award #Nominate
CC: @gdch
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RE: https://mstdn.science/@GDCh_BioChem/116594285990119910
A great opportunity to nominate PhD candidates for the #YoungScientistAward of @GDCh_BioChem! Self-nominations are also possible!
#Academia #Biochemistry #ChemBio #Chemistry #Award #Nominate
CC: @gdch
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RE: https://mstdn.science/@GDCh_BioChem/116594285990119910
A great opportunity to nominate PhD candidates for the #YoungScientistAward of @GDCh_BioChem! Self-nominations are also possible!
#Academia #Biochemistry #ChemBio #Chemistry #Award #Nominate
CC: @gdch
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RE: https://mstdn.science/@GDCh_BioChem/116594285990119910
A great opportunity to nominate PhD candidates for the #YoungScientistAward of @GDCh_BioChem! Self-nominations are also possible!
#Academia #Biochemistry #ChemBio #Chemistry #Award #Nominate
CC: @gdch
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RE: https://mstdn.science/@GDCh_BioChem/116594285990119910
A great opportunity to nominate PhD candidates for the #YoungScientistAward of @GDCh_BioChem! Self-nominations are also possible!
#Academia #Biochemistry #ChemBio #Chemistry #Award #Nominate
CC: @gdch
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The authors use affinity-based protein profiling with photoaffinity probes to elucidate PTM-dependent changes in protein ligandability in the proteome. To induce global changes of the PTM landscape, they use broad spectrum inhibitors like staurosporine to inhibit protein kinases and tunicamycin to inhibit N-linked glycosylation. Very interesting findings that many ligand interactions are affected either by direct or downstream effects. (2/2)
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The authors use affinity-based protein profiling with photoaffinity probes to elucidate PTM-dependent changes in protein ligandability in the proteome. To induce global changes of the PTM landscape, they use broad spectrum inhibitors like staurosporine to inhibit protein kinases and tunicamycin to inhibit N-linked glycosylation. Very interesting findings that many ligand interactions are affected either by direct or downstream effects. (2/2)
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The authors use affinity-based protein profiling with photoaffinity probes to elucidate PTM-dependent changes in protein ligandability in the proteome. To induce global changes of the PTM landscape, they use broad spectrum inhibitors like staurosporine to inhibit protein kinases and tunicamycin to inhibit N-linked glycosylation. Very interesting findings that many ligand interactions are affected either by direct or downstream effects. (2/2)
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The authors use affinity-based protein profiling with photoaffinity probes to elucidate PTM-dependent changes in protein ligandability in the proteome. To induce global changes of the PTM landscape, they use broad spectrum inhibitors like staurosporine to inhibit protein kinases and tunicamycin to inhibit N-linked glycosylation. Very interesting findings that many ligand interactions are affected either by direct or downstream effects. (2/2)
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The authors use affinity-based protein profiling with photoaffinity probes to elucidate PTM-dependent changes in protein ligandability in the proteome. To induce global changes of the PTM landscape, they use broad spectrum inhibitors like staurosporine to inhibit protein kinases and tunicamycin to inhibit N-linked glycosylation. Very interesting findings that many ligand interactions are affected either by direct or downstream effects. (2/2)
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We are looking for #PhDs and #Postdocs, who want to share their exciting #ChemBio research with a broad audience!
If you are interested, apply with a short abstract for a Flash Talk at the 6th Virtual ChemBioTalks on September 29th.
https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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We are looking for #PhDs and #Postdocs, who want to share their exciting #ChemBio research with a broad audience!
If you are interested, apply with a short abstract for a Flash Talk at the 6th Virtual ChemBioTalks on September 29th.
https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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We are looking for #PhDs and #Postdocs, who want to share their exciting #ChemBio research with a broad audience!
If you are interested, apply with a short abstract for a Flash Talk at the 6th Virtual ChemBioTalks on September 29th.
https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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We are looking for #PhDs and #Postdocs, who want to share their exciting #ChemBio research with a broad audience!
If you are interested, apply with a short abstract for a Flash Talk at the 6th Virtual ChemBioTalks on September 29th.
https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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We are looking for #PhDs and #Postdocs, who want to share their exciting #ChemBio research with a broad audience!
If you are interested, apply with a short abstract for a Flash Talk at the 6th Virtual ChemBioTalks on September 29th.
https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Very excited that Jon Stokes will visit us on May 28th for a @LED3hub Lecture. Very much looking forward to learning more about the potential of AI to speed up antibiotic discovery.
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Very excited that Jon Stokes will visit us on May 28th for a @LED3hub Lecture. Very much looking forward to learning more about the potential of AI to speed up antibiotic discovery.
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Very excited that Jon Stokes will visit us on May 28th for a @LED3hub Lecture. Very much looking forward to learning more about the potential of AI to speed up antibiotic discovery.
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Very excited that Jon Stokes will visit us on May 28th for a @LED3hub Lecture. Very much looking forward to learning more about the potential of AI to speed up antibiotic discovery.
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Very excited that Jon Stokes will visit us on May 28th for a @LED3hub Lecture. Very much looking forward to learning more about the potential of AI to speed up antibiotic discovery.
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We are looking forward to the LED3 Lecture by Jon Stokes on May 28th. He will talk about "An honest discussion about AI for antibiotic discovery "
If you are interested, make sure to come by!
https://www.universiteitleiden.nl/en/science/led3/led3-lectures
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We are looking forward to the LED3 Lecture by Jon Stokes on May 28th. He will talk about "An honest discussion about AI for antibiotic discovery "
If you are interested, make sure to come by!
https://www.universiteitleiden.nl/en/science/led3/led3-lectures
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We are looking forward to the LED3 Lecture by Jon Stokes on May 28th. He will talk about "An honest discussion about AI for antibiotic discovery "
If you are interested, make sure to come by!
https://www.universiteitleiden.nl/en/science/led3/led3-lectures
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We are looking forward to the LED3 Lecture by Jon Stokes on May 28th. He will talk about "An honest discussion about AI for antibiotic discovery "
If you are interested, make sure to come by!
https://www.universiteitleiden.nl/en/science/led3/led3-lectures
-
We are looking forward to the LED3 Lecture by Jon Stokes on May 28th. He will talk about "An honest discussion about AI for antibiotic discovery "
If you are interested, make sure to come by!
https://www.universiteitleiden.nl/en/science/led3/led3-lectures
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Another thought-provoking #MedChem #SciComm story by Stan Van Boeckel.
On the example of Sitagliptin, he explains the power of minimizing molecules and looking for the highest ligand efficiency in #DrugDiscovery.
#Chemistry #ChemBio #StoryTelling #SmallMolecules #LigandEfficiency #Science #Medicines
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Another thought-provoking #MedChem #SciComm story by Stan Van Boeckel.
On the example of Sitagliptin, he explains the power of minimizing molecules and looking for the highest ligand efficiency in #DrugDiscovery.
#Chemistry #ChemBio #StoryTelling #SmallMolecules #LigandEfficiency #Science #Medicines
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Another thought-provoking #MedChem #SciComm story by Stan Van Boeckel.
On the example of Sitagliptin, he explains the power of minimizing molecules and looking for the highest ligand efficiency in #DrugDiscovery.
#Chemistry #ChemBio #StoryTelling #SmallMolecules #LigandEfficiency #Science #Medicines
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Another thought-provoking #MedChem #SciComm story by Stan Van Boeckel.
On the example of Sitagliptin, he explains the power of minimizing molecules and looking for the highest ligand efficiency in #DrugDiscovery.
#Chemistry #ChemBio #StoryTelling #SmallMolecules #LigandEfficiency #Science #Medicines
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Another thought-provoking #MedChem #SciComm story by Stan Van Boeckel.
On the example of Sitagliptin, he explains the power of minimizing molecules and looking for the highest ligand efficiency in #DrugDiscovery.
#Chemistry #ChemBio #StoryTelling #SmallMolecules #LigandEfficiency #Science #Medicines
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We are again looking for 3 Flash Talks for the 6th Virtual @ChemBioTalks. If you are a PhD candidate or postdoc in the field of #ChemBio, I strongly encourage you to apply via our abstract challenge: https://chemistry-europe.onlinelibrary.wiley.com/hub/journal/14397633/chembio-flash
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Finally, he talked about the development of trimeric engagers (Multi-TACs) that can specifically bring together three different cell types. (3/3)
https://www.sciencedirect.com/science/article/pii/S009286742401198X
#Genetics #GeneticCodeExpension #ChemBio #Chemistry #Protein #RNA #GeneticCode #RNACodonExpansion
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Finally, he talked about the development of trimeric engagers (Multi-TACs) that can specifically bring together three different cell types. (3/3)
https://www.sciencedirect.com/science/article/pii/S009286742401198X
#Genetics #GeneticCodeExpension #ChemBio #Chemistry #Protein #RNA #GeneticCode #RNACodonExpansion
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Finally, he talked about the development of trimeric engagers (Multi-TACs) that can specifically bring together three different cell types. (3/3)
https://www.sciencedirect.com/science/article/pii/S009286742401198X
#Genetics #GeneticCodeExpension #ChemBio #Chemistry #Protein #RNA #GeneticCode #RNACodonExpansion