#sle — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #sle, aggregated by home.social.
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https://www.europesays.com/at/164888/ Calcidiol als möglicher kardiovaskulärer Risikomarker bei SLE #25HydroxyvitaminD #25(OH)D #AT #Austria #Calcidiol #Gesundheit #Health #KardiovaskuläresRisiko #Mortalität #Myokardinfarkt #Österreich #Schlaganfall #SLE #SystemischerLupusErythematodes #VitaminD #VitaminDMangel
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Mebendazole for Systemic Lupus Erythematosus? New 2026 Study Sparks Interest in Repurposed Autoimmune Treatments A newly published 2026 study has reignited interest in an unlikely candidate for aut...
#autoimmune #mebendazole #repurposed #drugs #SLE
Origin | Interest | Match -
https://www.europesays.com/ch/30378/ Roche lupus drug cuts disease activity in phase III #ClinicalTrial #Gazyva #Gazyvaro #lupus #NEJM #PhaseIII #RHHBY #Roche #SLE
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#Lupus and LupusNephritis (LN) can be diagnosed TOGETHER for as many as 30% of lupus patients. As many as 60% of Lupus #SLE patients will see kidney impact.
YOU deserve better!
Ask your provider for treatments leading to #lupusremission as outlined by the American College of Rheumatology. #shareddecisionmaking.
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Loss-of-function mutations in PLD4 linked to SLE:
🔬 PLD4 mutations led to high TLR7/9 activation
🔬 5 patients showed reduced exonuclease activity
🔬 Effective baricitinib treatment in mice#SLE #Genetics #Inflammation #Pub2Post
https://tnyp.me/vwTf6xf5/m -
❄️ Schneeflöckchen, Weißröckchen… Heute kommt unser letzter #CharitéScienceShot geschneit. Wir verabschieden uns von einem lehrreichen 2025 und wünschen eine besinnliche Adventszeit! Unser lieblicher Stern wohnt übrigens nicht in den Wolken. Sondern?
#Wissenschaft #Forschung #Medizin #ScienceMastodon #Fotografie #photography #Lupus #SLE
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Desde el domingo con brote de #EncefalomielitisMiálgica y crisis de dolor neuropático. Al menos hoy duele menos al teclear.
A #MyalgicEncephalomyelitis crash (flare) and neuropathic pain crisis since Sunday. Typing hurts less but still.
#Dolor #DolorNeuropatico #DolorCronico #EMsfc #fibromialgia#Sjögen #Lupus #LES #NeuralgiaDelTrigemino #NdT #Migraña #Pain #ChronicPain #neuropathicPain #ME #MEcfs #fibromyalgia #Sjögrens #SLE #TrigeminalNervePain #TNP #Migraine
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#SUSECON 2025: #SUSE setzt auf #KI und erweiterte #SLE -Unterstützung - #fosstopia
#SUSE hat auf der diesjährigen #SUSECON in Orlando klargestellt, dass es bei der KI-Revolution mitmischen will. Neben einer Reihe von Anwendungsfällen für künstliche Intelligenz gab es auch spannende Neuerungen für Admins im Hinblick auf die verschiedene #Linux-Distributionen.
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" The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature
in #monocytes and #Tcells of #SLE patients"https://insight.jci.org/articles/view/179433
Striking that this apparently works better in getting rid of certain memory #Bcells than anti-CD20 antibodies.
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Lo prometido es deuda.
Si has visto la serie "Dr House" sabes que cada vez que entraba alguien de urgencias medio muriéndose sin responder a nada, el equipo médico hacía un diagnostico diferencial con el lupus para descartarlo.
Pero seguramente no sepas mucho más. Aprende aquí:#179 #Lupus 10 preguntas básicas por el #DiaMundialdelLupus 🐺
https://domandoallobo.blogspot.com/2016/05/179-lupus-10-preguntas-basicas-por-el.html #blog #mastoblogs #mastobloggers #LES #SLE #autoinmunes #Autoimmunes #DisOrganic #Discapacidad -
'The results provide evidence that elevated IFNα levels act directly on B cells to facilitate autoantibody production and further highlight the importance of IFN signaling as a potential therapeutic target in SLE.'
#immunology #interferon #Lupus #SLE #AutoAntibodies #Autoimmunity
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Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
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Even Aushra Augustanavichute in her work on the concept of socionics wrote that this is still raw, but they are open to dialogue in the world. Especially if you consider that they had only a few descriptions for SLE.
#socionics #psychosophy #Artist #SLE -
Looking at proteolytis in human plasma, we observed a lot of cleavages in complement C3, with known cleavages for C3a, C3b, and C3(d)g - but also a yet not deeply investigated cleavage at pos. 1514, which represented for us a quite intriguing lupus-enriched cleavage, thus we named it C3-LHF1 for complement "C3 Lupus Human Fragment 1" #C3 #Complement #LHF1 #SLE #Lupus 3/n
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Impressive case at #CharitéBerlin: In a 23-year-old female patient with severe systemic #lupus erythematosus, the #AutoimmuneDisease is no longer detectable after treatment with a cancer medication. Only time will tell if the results will last, but the case marks the starting point for further studies.
#Medicine #Science #Research #ScienceMastodon #MedMastodon #Medibubble #SLE #CharitéImmunology #autoimmunity
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💪 #SLE2026 website is live 💪
The #ACM #SIGPLAN International Conference on #Software #Language Engineering (#SLE) is devoted to the principles of software languages: their design, their implementation, and their evolution. And of course, the role #AI can play in all these tasks.
Start preparing your:
☑️ Research Papers
☑️ New ideas Papers
☑️ Tool Papers
I can't think of a better excuse to escape your never-ending Christmas feasts 😉 🎅⛄
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As a follow-up to this thread: there is now also an editorial emphasizing the value of our resource for the community: https://www.embopress.org/doi/full/10.1038/s44318-025-00633-8
Special emphasis on the non-canonical functions of the human complement system. #SLE #Ntermini #EMBOJournal -
Three women—a single mom with a high-risk pregnancy; a young woman with deteriorating lupus; a widow with a severe dental condition—are facing medical emergencies.
No goal today (I can’t type them anymore, and they don’t move, anyway). ANYTHING helps. Click WEEKLY to sustain hope.
https://chuffed.org/project/hope-giving-circle
@mutualaid @palestine
#MutualAid #MutualAidRequest #Gaza #Palestine #Lupus #SLE -
After a looong journey, I can present you the results of a deep & thorough investigation of human plasma proteolysis by mass spec: SLE N-terminomics paper with a complement C3 fragment(s) is out now in EMBOJ: https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8 - highlights: a nice resource on proteolytically processed N-termini in human plasma of healthy & SLE patients, with a lot of complement bonus for all interested scientists. #SLE #Science #Proteomics #TeamMassSpec #InflammatoryDisease #LupusResearch #C3 #LHF1 1/10
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Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 081756Z 02009KT 10SM BKN030 OVC037 13/07 A2986 RMK AO2 SLP111 T01330072 10133 20083 58001” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
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Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 081756Z 02009KT 10SM BKN030 OVC037 13/07 A2986 RMK AO2 SLP111 T01330072 10133 20083 58001” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vii3
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Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 011756Z COR 18005KT 5SM -RA BR SCT041 SCT060 OVC080 16/13 A2986 RMK AO2 SLP112 P0002 60007 T01560133 10156 20139 51010 $” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
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Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 011756Z COR 18005KT 5SM -RA BR SCT041 SCT060 OVC080 16/13 A2986 RMK AO2 SLP112 P0002 60007 T01560133 10156 20139 51010 $” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vii3
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Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 231856Z 34005KT 10SM CLR 30/09 A2988 RMK AO2 SLP115 T03000094” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
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@viq @aceryz @nixCraft wow nice! So if i can get that vaccine for my SLE (MCTD actually), then it might cure my t1d also?
Sign me up!(For extra credit in willing to be cured of the hypothyroid also... 🐵😉)
So... I'd love to read more about that, if you have a fave source of info...?
(Ps- good luck everybody!)
#t1d #sle #lupus #MCTD #autoimmune -
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 051756Z 35009KT 10SM OVC021 16/10 A3008 RMK AO2 SLP184 T01610100 10161 20122 58001 $” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
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🎙️📢 I'll be at #OOPSLE giving the #invited #talk:
Who will create the #languages of the future? (hint: probably not a team of language #engineers!)
where I'll think out loud about WHO (and HOW) will define all the #good #languages we need to cover the growing #software demands of our #society. AI? End-users? Domain experts? Language engineers? 🤔
This talk aims to be a "meta" version of one I've often been giving lately: Who will develop the apps of the future? (hint: it’s not going to be a team of human programmers) ➡️ https://livablesoftware.com/who-will-develop-apps-future/
While I prepare the talk, I'd love to get your thoughts on:
- How do you see the evolution of language engineering
- What are the main challenges?
- What is the impact of AI in this field?
- What would you like me to talk about?All comments welcome 🙏🙏
🔗 OOPSLE: https://conf.researchr.org/home/staf-2025/oopsle-2025#program
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@evilcookies98 I upgraded to a pair from SleepPhones last Christmas. I used to buy a $20 pair from Amazon, but decided to see what a nicer pair was like. SleepPhones sells them in sizes and different materials. They're also call AcousticSheep! #SLE E pPhones #AcousticSheep https://www.sleepphones.com/
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🎙️📢 I'll be at #OOPSLE giving the #invited #talk:
Who will create the #languages of the future? (hint: probably not a team of language #engineers!)
where I'll think out loud about WHO (and HOW) will define all the #good #languages we need to cover the growing #software demands of our #society. AI? End-users? Domain experts? Language engineers? 🤔
This talk aims to be a "meta" version of one I've often been giving lately: Who will develop the apps of the future? (hint: it’s not going to be a team of human programmers) ➡️ https://livablesoftware.com/who-will-develop-apps-future/
While I prepare the talk, I'd love to get your thoughts on:
- How do you see the evolution of language engineering
- What are the main challenges?
- What is the impact of AI in this field?
- What would you like me to talk about?All comments welcome 🙏🙏
🔗 OOPSLE: https://conf.researchr.org/home/staf-2025/oopsle-2025#program
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🎙️📢 I'll be at #OOPSLE giving the #invited #talk:
Who will create the #languages of the future? (hint: probably not a team of language #engineers!)
where I'll think out loud about WHO (and HOW) will define all the #good #languages we need to cover the growing #software demands of our #society. AI? End-users? Domain experts? Language engineers? 🤔
This talk aims to be a "meta" version of one I've often been giving lately: Who will develop the apps of the future? (hint: it’s not going to be a team of human programmers) ➡️ https://livablesoftware.com/who-will-develop-apps-future/
While I prepare the talk, I'd love to get your thoughts on:
- How do you see the evolution of language engineering
- What are the main challenges?
- What is the impact of AI in this field?
- What would you like me to talk about?All comments welcome 🙏🙏
🔗 OOPSLE: https://conf.researchr.org/home/staf-2025/oopsle-2025#program
-
🎙️📢 I'll be at #OOPSLE giving the #invited #talk:
Who will create the #languages of the future? (hint: probably not a team of language #engineers!)
where I'll think out loud about WHO (and HOW) will define all the #good #languages we need to cover the growing #software demands of our #society. AI? End-users? Domain experts? Language engineers? 🤔
This talk aims to be a "meta" version of one I've often been giving lately: Who will develop the apps of the future? (hint: it’s not going to be a team of human programmers) ➡️ https://livablesoftware.com/who-will-develop-apps-future/
While I prepare the talk, I'd love to get your thoughts on:
- How do you see the evolution of language engineering
- What are the main challenges?
- What is the impact of AI in this field?
- What would you like me to talk about?All comments welcome 🙏🙏
🔗 OOPSLE: https://conf.researchr.org/home/staf-2025/oopsle-2025#program
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Hi! Just trying out Mastadon. I am a complex trait geneticist working on the functional annotation of risk loci for SLE using multi-omic technologies. I am also a qualified mediator with a special interest in resolving disputes between PhD students and their supervisors.#Introduction #bioinformatics #SLE #multi-omic #functionalgeonomics #ImmunoGenetics #mediation #scienceculture
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La cantante #Halsey tiene #Lupus Eritematoso Sistémico #LES (#SLE en inglés), como el mío -hay varios tipos.
Muestra el rash típico en forma de alas de mariposa 🦋 Hace hasta que se vea hermoso pero pica, quema, duele. La advertencia de un lobo que debora por dentro.Os dejo la pestaña del #blog dedicada a esta enfermedad autoinmune por si queréis saber más. Unos posts dan una visión general de la patología y otros, aspectos más concretos:
🐺 https://domandoallobo.blogspot.com/p/lupus-y-sjogren.html
#mastoblogs #Autoinmunes -
Gonna be a hot day today... uv protection is important 😆 can never have enough of it it seems #uvprotection #photosensitivity #SLE
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#esittely
#RIPTwitteristä siirtynyt peruskoulun kielenopesta 50vee alaa vaihtanut olio, buumeri, joka pohtii mitä tehdä isona. Seuraan harvinaissairauden tutkimusta toivottavasti täälläkin, se on edennyt harppauksin 10 vuoden aikana.
#Helsinki #ilmastokriisi #luontokato #ihmisoikeudet #politiikka #turpo#introduction
Lupus Europe PAN member #Lupus #LupusResearch #SLE
#climate #ukraine #nafo #fellas -
Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
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Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
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Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
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Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
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New research in #Rheumatology shows that #ClonalHematopoiesis is much more common in patients with #Lupus (#SLE) than the overall population. However, the prevalence didn't appear to be associated with use of immunosuppressive therapies: https://academic.oup.com/rheumatology/article-abstract/61/11/4355/6530303 #medicine #science
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Researchers at #CharitéBerlin, German Rheumatology Research Center and @MDC_Berlin have identified the immune cells that cause severe #kidney #inflammation in patients with #lupus. The study, published in the journal #nature, could pave the way for future antibody therapies.
#CharitéPaper #medicine #science #research #ImmuneSystem #SLE #nephritis #MedMastodon #CharitéImmunology
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Forschende der #CharitéBerlin, des Deutschen Rheumaforschungszentrums und des @MDC_Berlin haben Immunzellen identifiziert, die bei #Lupus eine schwere Nierenentzündung verursachen. Die im Fachmagazin #Nature publizierte Studie könnte den Weg für künftige Antikörpertherapien ebnen.
#CharitéPaper #Medizin #Wissenschaft #Forschung #CharitéImmunologie #Immunsystem #SLE #Nephritis #MedMastodon #MediBubble
