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  1. Scientists Discover Neural Basis of Schizophrenia and Bipolar Disorder -SciTechDaily.com

    Tiny engineered brain models reveal that psychiatric disorders may arise from distinctive disruptions in neural communication rather than obvious structural damage. Credit: SciTechDaily.com

    Health

    Scientists Discover Neural Basis of Schizophrenia and Bipolar Disorder

    By Roberto Molar Candanosa, Johns Hopkins University, December 20, 2025, 8 Comments,
    5 Mins Read

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    Using lab-grown brain tissue, researchers uncovered complex patterns of neural signaling that differ subtly between healthy brains and those linked to severe psychiatric disorders.

    For the first time, scientists have used pea-sized brain organoids grown in the laboratory to uncover how neurons may malfunction in schizophrenia and bipolar disorder. These psychiatric conditions affect millions of people around the world, yet they remain difficult to diagnose because researchers still lack a clear understanding of their underlying molecular mechanisms.

    The results could eventually help clinicians reduce diagnostic uncertainty when treating these and other mental health conditions. At present, such disorders are typically identified through clinical judgment alone, and treatment often relies on lengthy trial-and-error approaches to medication.

    A detailed account of the findings was published in the journal APL Bioengineering.

    “Schizophrenia and bipolar disorder are very hard to diagnose because no particular part of the brain goes off. No specific enzymes are going off like in Parkinson’s, another neurological disease where doctors can diagnose and treat based on dopamine levels even though it still doesn’t have a proper cure,” said Annie Kathuria, a Johns Hopkins University biomedical engineer who led the research. “Our hope is that in the future we can not only confirm a patient is schizophrenic or bipolar from brain organoids, but that we can also start testing drugs on the organoids to find out what drug concentrations might help them get to a healthy state.”

    Annie Kathuria. Credit: Will Kirk / Johns Hopkins University

    Machine learning decodes disease specific signals

    Kathuria’s team created the organoids, simplified versions of brain tissue, by reprogramming blood and skin cells from people with schizophrenia, bipolar disorder, and from healthy volunteers into stem cells capable of forming brain-like structures. They then applied machine learning tools to analyze the electrical activity of the organoids’ cells, allowing them to identify neural firing patterns associated with healthy and diseased states. In the human brain, neurons communicate through small electrical signals.

    Continue/Read Original Article Here: Scientists Discover Neural Basis of Schizophrenia and Bipolar Disorder

    Tags: Annie Kathuria, Biomedical Engineer, Bipolar Disorder, Discover, Health Research, Johns Hopkins University, Mental Health, Neural Basis, Schizophrenia, Scientists, SciTechDaily
    #AnnieKathuria #BiomedicalEngineer #BipolarDisorder #Discover #HealthResearch #JohnsHopkinsUniversity #MentalHealth #NeuralBasis #Schizophrenia #Scientists #SciTechDaily
  2. Baltimore Banner: Johns Hopkins University Press will license its authors’ books to train AI models. “The Johns Hopkins University will license its books to train proprietary large language models, an advanced form of artificial intelligence that generates human-like language, the school’s publishing division announced this week. Authors have until the end of August to opt out of the […]

    https://rbfirehose.com/2025/08/02/baltimore-banner-johns-hopkins-university-press-will-license-its-authors-books-to-train-ai-model/

  3. Johns Hopkins University: Former Sen. Ben Cardin donates political papers to Johns Hopkins. “The legislative and political papers of former U.S. Sen. Ben Cardin have found a new home at Johns Hopkins University’s Sheridan Libraries and University Museums.”

    https://rbfirehose.com/2025/07/09/johns-hopkins-university-former-sen-ben-cardin-donates-political-papers-to-johns-hopkins/

  4. Missed our #Farbindungen23 keynote this year, ft. Chaya Nove and and Rivke Margolis? Zorgt zikh nit — worry not! It's available in its entirety on our YouTube channel. Git a kuk!
    🎬 youtube.com/watch?v=D2Wjvh-Ym7

    And save the Date for #Farbindungen24, taking place virtually Feb. 18-19, 2024 with support from the Leonard and Helen R. Stulman #Jewish Studies Program at #JohnsHopkinsUniversity. Mir kukn shoyn aroys! We're already looking forward!

    #Yiddish #conference #Hasidic #film #Chassidic

  5. #JOHNSHOPKINSUNIVERSITY (#JHU) continues to pad its #space community résumé with its #interactivemap, “The map of the observable Universe,” that takes viewers on a 13.7-billion-year-old tour of the #cosmos from the present to the moments after the #BigBang. While JHU is responsible for creating the site, additional contributions were made by #NASA, the #EuropeanSpaceAgency, the #NationalScienceFoundation, and the #SloanFoundation.

    inverse.com/science/map-of-the

    #astronomy #science #website #websites

  6. Die Zahl der Corona-Toten hat einen neuen Höchststand erreicht. Aber warum? Wir sind wieder im Lockdown. Wir treffen uns kaum noch mit anderen Menschen. Trotzdem steigen die Zahlen. Gibt es dafür eindeutige Gründe?
    Warum die Zahl der Corona-Toten wieder steigt | DW | 15.01.2021 #Corona #COVID-19 #Sterbefälle #RKI #JohnsHopkinsUniversity #Sterberate