#enzymes — Public Fediverse posts

The #robberfly #Tolmerus #cingulatus is native to the Palearctic and prefers dry #habitats. #Adults #prey on other insects, killing their prey with #neurotoxins, predigest via #enzymes. Larvae are soil predators. R. Mitchell (2024) presents a #genome (280,000 megabases) for the #DarwinTreeofLife. See also my science blog article (2024).

©#StefanFWirth #Berlin 2025

Ref

R. Mitchell (2024)
https://doi.org/10.12688/wellcomeopenres.23416.1

S. F. Wirth on " biologe"" (2024)
https://wp.me/p2l6XU-1UV

Photos
© S.F. Wirth

"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"

https://www.nature.com/articles/s41559-024-02361-4

"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"

https://www.nature.com/articles/s41559-024-02361-4

"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"

https://www.nature.com/articles/s41559-024-02361-4

"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"

https://www.nature.com/articles/s41559-024-02361-4

"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"

https://www.nature.com/articles/s41559-024-02361-4

Hi @DNPFred
In grad school I worked on heme proteins using #paramagnetic #NMR and #NRVS. Then I shifted to #XRayCrystallography, using #EPR #UVVis and #EDX on #crystals when a postdoc. My research group works on #NonHemeIron #enzymes, & #heme, #copper & #manganese #metalloproteins. Really interested in combining #spectroscopy on #protein #crystals to examine #structure #function relationships.