#proteinscience — Public Fediverse posts

🧪 Daily Lab Note

Protein Myths Busted: What Science Really Says About Recovery
May 10, 2026 | Lab Notes

· New research suggests protein supplements aid recovery mainly through added calories, not protein alone
· Pre-exercise meals can change how effective post-workout carbohydrates are
· Science is rethinking common recovery nutrition strategies

#ProteinScience #RecoveryNutrition #FitnessMyths

https://s.fitbodyscience.com/zKeWDu

🧩 Could RNA and proteins share the same “shape language” for binding drugs?

🔗 Eigenvalue Ratios Reveal Shared Binding Pocket Shapes in RNA and Protein Structures. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0022

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #StructuralBiology #ComputationalBiology #RNAResearch #ProteinScience #Bioinformatics #MolecularModeling #Genomics #Proteomics #Cheminformatics #LigandBinding

🧩 Could RNA and proteins share the same “shape language” for binding drugs?

🔗 Eigenvalue Ratios Reveal Shared Binding Pocket Shapes in RNA and Protein Structures. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0022

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #StructuralBiology #ComputationalBiology #RNAResearch #ProteinScience #Bioinformatics #MolecularModeling #Genomics #Proteomics #Cheminformatics #LigandBinding

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

🧩 What if the diverse functions of a single protein all trace back to one structural superfamily?

🔗 Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.003

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ComputationalBiology #MolecularEvolution #ProteinScience #Genomics #Proteomics #AlphaFold #MembraneProteins #Genetics #Bioinformatics

🧩 What if the diverse functions of a single protein all trace back to one structural superfamily?

🔗 Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.003

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ComputationalBiology #MolecularEvolution #ProteinScience #Genomics #Proteomics #AlphaFold #MembraneProteins #Genetics #Bioinformatics

🧩 What if the diverse functions of a single protein all trace back to one structural superfamily?

🔗 Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.003

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ComputationalBiology #MolecularEvolution #ProteinScience #Genomics #Proteomics #AlphaFold #MembraneProteins #Genetics #Bioinformatics

🧩 What if the diverse functions of a single protein all trace back to one structural superfamily?

🔗 Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.003

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ComputationalBiology #MolecularEvolution #ProteinScience #Genomics #Proteomics #AlphaFold #MembraneProteins #Genetics #Bioinformatics

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

💪 Could one molecular “typo” break the balance between strength and flexibility in our muscles?

🔗 Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

🧬 Can we turn evolutionary signatures into maps of protein function?

🔗 Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.012

📚 CSBJ: https://www.csbj.org/

#ProteinScience #StructuralBiology #ProteoSync #ComputationalBiology #Bioinformatics #EvolutionaryBiology #MolecularBiology #PyMOL

🧬 Can we turn evolutionary signatures into maps of protein function?

🔗 Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.012

📚 CSBJ: https://www.csbj.org/

#ProteinScience #StructuralBiology #ProteoSync #ComputationalBiology #Bioinformatics #EvolutionaryBiology #MolecularBiology #PyMOL

🧬 Can we turn evolutionary signatures into maps of protein function?

🔗 Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.012

📚 CSBJ: https://www.csbj.org/

#ProteinScience #StructuralBiology #ProteoSync #ComputationalBiology #Bioinformatics #EvolutionaryBiology #MolecularBiology #PyMOL

🧬 Can we turn evolutionary signatures into maps of protein function?

🔗 Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.012

📚 CSBJ: https://www.csbj.org/

#ProteinScience #StructuralBiology #ProteoSync #ComputationalBiology #Bioinformatics #EvolutionaryBiology #MolecularBiology #PyMOL

🪨 Can sand-like molecules help us map the secrets of protein structure?

🔗 Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

📚 CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

🪨 Can sand-like molecules help us map the secrets of protein structure?

🔗 Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

📚 CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

🪨 Can sand-like molecules help us map the secrets of protein structure?

🔗 Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

📚 CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

🪨 Can sand-like molecules help us map the secrets of protein structure?

🔗 Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

📚 CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

🪨 Can sand-like molecules help us map the secrets of protein structure?

🔗 Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

📚 CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

⚛️ Have proteins evolved to operate at a quantum sweet spot between conduction and insulation?

🔗 Holographic nature of critical quantum states of proteins. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.049

📚 CSBJ Quantum Biology and Biophotonics: https://www.csbj.org/qbio

#QuantumBiology #ProteinScience #Biophysics #AndersonTransition #Holography #Bioelectronics #Nanotechnology

🛠️ Is it possible to rewire cellular energy control by targeting a single protein domain?

🔗 Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.007

📚 CSBJ: https://www.csbj.org/

#Mitochondria #CellBiology #CalciumSignaling #ProteinEngineering #ProteinScience #StructuralBiology #Bioenergetics #MolecularDynamics #Biophysics #MCU #MCUb #NMR

This study introduces plmCP, an innovative method for detecting circular permutations (CPs) in proteins using Protein Language Models (PLMs)—paving the way for deeper insights into protein evolution, engineering, and synthetic biology.

🔗 Detection of circular permutations by Protein Language Models. Computational and Structural Biotech Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.029

📚 CSBJ: https://www.csbj.org/

#ProteinScience #AIinBiotech #SyntheticBiology #Bioinformatics #ProteinEngineering

This study investigates the surprising limitations of AlphaFold 2 (AF2) in predicting protein structures—specifically its tendency to confidently predict β-solenoid folds for repeat proteins, even when the structures are unrealistic or unstable.

🔗 AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic β-solenoid structures for repeat proteins. DOI: https://doi.org/10.1016/j.csbj.2025.01.016

📚 CSBJ: https://www.csbj.org/

#AlphaFold #ProteinScience #StructuralBiology #DeepLearning

Scientists have cracked the code behind proteins’ extraordinary structures, unravelling how these molecular machines fold into shapes critical for life. This breakthrough deepens our understanding of biology and opens the door to designing custom proteins for medicine, energy, and materials. Could this reshape how we engineer solutions at the molecular level? #ProteinScience #Biotechnology #Innovation
https://www.nobelprize.org/prizes/chemistry/2024/press-release/

Scientists have cracked the code behind proteins’ extraordinary structures, unravelling how these molecular machines fold into shapes critical for life. This breakthrough deepens our understanding of biology and opens the door to designing custom proteins for medicine, energy, and materials. Could this reshape how we engineer solutions at the molecular level? #ProteinScience #Biotechnology #Innovation
https://www.nobelprize.org/prizes/chemistry/2024/press-release/

Scientists have cracked the code behind proteins’ extraordinary structures, unravelling how these molecular machines fold into shapes critical for life. This breakthrough deepens our understanding of biology and opens the door to designing custom proteins for medicine, energy, and materials. Could this reshape how we engineer solutions at the molecular level? #ProteinScience #Biotechnology #Innovation
https://www.nobelprize.org/prizes/chemistry/2024/press-release/

Scientists have cracked the code behind proteins’ extraordinary structures, unravelling how these molecular machines fold into shapes critical for life. This breakthrough deepens our understanding of biology and opens the door to designing custom proteins for medicine, energy, and materials. Could this reshape how we engineer solutions at the molecular level? #ProteinScience #Biotechnology #Innovation
https://www.nobelprize.org/prizes/chemistry/2024/press-release/

Scientists have cracked the code behind proteins’ extraordinary structures, unravelling how these molecular machines fold into shapes critical for life. This breakthrough deepens our understanding of biology and opens the door to designing custom proteins for medicine, energy, and materials. Could this reshape how we engineer solutions at the molecular level? #ProteinScience #Biotechnology #Innovation
https://www.nobelprize.org/prizes/chemistry/2024/press-release/

AI has transformed protein science, predicting structures with unprecedented speed and accuracy. Yet, while tools like AlphaFold have revolutionized the field, the work is far from over. Understanding protein dynamics, interactions, and functions requires experimental and theoretical advances. AI is a powerful ally in decoding life’s molecular machinery. #AI #ProteinScience #Biotechnology
https://www.quantamagazine.org/how-ai-revolutionized-protein-science-but-didnt-end-it-20240626/

AI has transformed protein science, predicting structures with unprecedented speed and accuracy. Yet, while tools like AlphaFold have revolutionized the field, the work is far from over. Understanding protein dynamics, interactions, and functions requires experimental and theoretical advances. AI is a powerful ally in decoding life’s molecular machinery. #AI #ProteinScience #Biotechnology
https://www.quantamagazine.org/how-ai-revolutionized-protein-science-but-didnt-end-it-20240626/

AI has transformed protein science, predicting structures with unprecedented speed and accuracy. Yet, while tools like AlphaFold have revolutionized the field, the work is far from over. Understanding protein dynamics, interactions, and functions requires experimental and theoretical advances. AI is a powerful ally in decoding life’s molecular machinery. #AI #ProteinScience #Biotechnology
https://www.quantamagazine.org/how-ai-revolutionized-protein-science-but-didnt-end-it-20240626/

AI has transformed protein science, predicting structures with unprecedented speed and accuracy. Yet, while tools like AlphaFold have revolutionized the field, the work is far from over. Understanding protein dynamics, interactions, and functions requires experimental and theoretical advances. AI is a powerful ally in decoding life’s molecular machinery. #AI #ProteinScience #Biotechnology
https://www.quantamagazine.org/how-ai-revolutionized-protein-science-but-didnt-end-it-20240626/

AI has transformed protein science, predicting structures with unprecedented speed and accuracy. Yet, while tools like AlphaFold have revolutionized the field, the work is far from over. Understanding protein dynamics, interactions, and functions requires experimental and theoretical advances. AI is a powerful ally in decoding life’s molecular machinery. #AI #ProteinScience #Biotechnology
https://www.quantamagazine.org/how-ai-revolutionized-protein-science-but-didnt-end-it-20240626/

:labcoat: Nanopore sequencing is a new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore.

This method can detect post-translational modifications, including phosphorylation, in full-length protein structures at single molecule resolution.

https://www.chemistryworld.com/news/nanopore-sequencing-set-to-transform-our-understanding-of-proteins/4020177.article

#ChemToots #ChemiVerse #ProteinScience #Protein

:labcoat: Nanopore sequencing is a new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore.

This method can detect post-translational modifications, including phosphorylation, in full-length protein structures at single molecule resolution.

https://www.chemistryworld.com/news/nanopore-sequencing-set-to-transform-our-understanding-of-proteins/4020177.article

#ChemToots #ChemiVerse #ProteinScience #Protein

:labcoat: Nanopore sequencing is a new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore.

This method can detect post-translational modifications, including phosphorylation, in full-length protein structures at single molecule resolution.

https://www.chemistryworld.com/news/nanopore-sequencing-set-to-transform-our-understanding-of-proteins/4020177.article

#ChemToots #ChemiVerse #ProteinScience #Protein

:labcoat: Nanopore sequencing is a new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore.

This method can detect post-translational modifications, including phosphorylation, in full-length protein structures at single molecule resolution.

https://www.chemistryworld.com/news/nanopore-sequencing-set-to-transform-our-understanding-of-proteins/4020177.article

#ChemToots #ChemiVerse #ProteinScience #Protein

:labcoat: Nanopore sequencing is a new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore.

This method can detect post-translational modifications, including phosphorylation, in full-length protein structures at single molecule resolution.

https://www.chemistryworld.com/news/nanopore-sequencing-set-to-transform-our-understanding-of-proteins/4020177.article

#ChemToots #ChemiVerse #ProteinScience #Protein

Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel @gomobel
25 January 2024

https://www.chemistryworld.com/news/autonomous-platform-engineers-enhanced-proteins/4018841.article

#ChemiVerse #ProteinScience #ProteinEngineering #SyntheticBiology

Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel @gomobel
25 January 2024

https://www.chemistryworld.com/news/autonomous-platform-engineers-enhanced-proteins/4018841.article

#ChemiVerse #ProteinScience #ProteinEngineering #SyntheticBiology

Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel @gomobel
25 January 2024

https://www.chemistryworld.com/news/autonomous-platform-engineers-enhanced-proteins/4018841.article

#ChemiVerse #ProteinScience #ProteinEngineering #SyntheticBiology

Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel @gomobel
25 January 2024

https://www.chemistryworld.com/news/autonomous-platform-engineers-enhanced-proteins/4018841.article

#ChemiVerse #ProteinScience #ProteinEngineering #SyntheticBiology

Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel @gomobel
25 January 2024

https://www.chemistryworld.com/news/autonomous-platform-engineers-enhanced-proteins/4018841.article

#ChemiVerse #ProteinScience #ProteinEngineering #SyntheticBiology