#biosynthesis — Public Fediverse posts

A new study in #JIPB reveals how bollworms suppress #plant defenses.
Wang et al. report #cotton bollworm effector HYPB1 targets dirigent protein GhDIR15, suppressing lignin #biosynthesis and weakening cell wall-mediated defense.
https://doi.org/10.1111/jipb.70270
@WileyLifeSci
#PlantSci #botany

A new study in #JIPB reveals how bollworms suppress #plant defenses.
Wang et al. report #cotton bollworm effector HYPB1 targets dirigent protein GhDIR15, suppressing lignin #biosynthesis and weakening cell wall-mediated defense.
https://doi.org/10.1111/jipb.70270
@WileyLifeSci
#PlantSci #botany

🚨Special issue alert!

Our latest focus issue, "Advances in Plant Natural Products: Biosynthesis, Bioengineering, and Applications," is out now!

Find it here: https://onlinelibrary.wiley.com/toc/17447909/2026/68/4

@WileyLifeSci
#PlantScience #JIPB #biosynthesis #bioengineering #botany

🚨Special issue alert!

Our latest focus issue, "Advances in Plant Natural Products: Biosynthesis, Bioengineering, and Applications," is out now!

Find it here: https://onlinelibrary.wiley.com/toc/17447909/2026/68/4

@WileyLifeSci
#PlantScience #JIPB #biosynthesis #bioengineering #botany

https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html

(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)

Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.

https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html

(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)

Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.

https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html

(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)

Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.

https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html

(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)

Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.

https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html

(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)

Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.

🥝No one comes for our kiwis!
Song et al. report the AcLFYL1-AcCSE module enhances #kiwifruit resistance to Pseudomonas syringae pv. actinidiae by regulating #cell density and lignin #biosynthesis.
🥝Take that, canker disease!
https://doi.org/10.1111/jipb.70232
@WileyLifeSci
#PlantSci #JIPB #botany

🥝No one comes for our kiwis!
Song et al. report the AcLFYL1-AcCSE module enhances #kiwifruit resistance to Pseudomonas syringae pv. actinidiae by regulating #cell density and lignin #biosynthesis.
🥝Take that, canker disease!
https://doi.org/10.1111/jipb.70232
@WileyLifeSci
#PlantSci #JIPB #botany

New publication: #Plant Coumarins #Modulate Natural Product #Biosynthesis in a #Streptomyces #Root #Endophyte.
https://doi.org/10.1021/acs.jnatprod.5c01626

New publication: #Plant Coumarins #Modulate Natural Product #Biosynthesis in a #Streptomyces #Root #Endophyte.
https://doi.org/10.1021/acs.jnatprod.5c01626

New publication: #Plant Coumarins #Modulate Natural Product #Biosynthesis in a #Streptomyces #Root #Endophyte.
https://doi.org/10.1021/acs.jnatprod.5c01626

New publication: #Plant Coumarins #Modulate Natural Product #Biosynthesis in a #Streptomyces #Root #Endophyte.
https://doi.org/10.1021/acs.jnatprod.5c01626

🛡️Xu et al. reveal a striking #evolutionary divergence in the regulatory mechanisms of salicylic acid #biosynthesis between N. benthamiana and #Arabidopsis.
⬇️Get a free sneak peek at this new work right here!
⚔️https://doi.org/10.1111/jipb.70214
@WileyLifeSci
#PlantScience #CropSci #JIPB

🛡️Xu et al. reveal a striking #evolutionary divergence in the regulatory mechanisms of salicylic acid #biosynthesis between N. benthamiana and #Arabidopsis.
⬇️Get a free sneak peek at this new work right here!
⚔️https://doi.org/10.1111/jipb.70214
@WileyLifeSci
#PlantScience #CropSci #JIPB

🧪Phillyrin is a unique #antiviral lignan with potent anti-#flu activity only found in Forsythia suspensa.
Wang et al. reveal key steps in its #biosynthesis, bringing us one step closer to a valuable #drug.
🔗https://doi.org/10.1111/jipb.70216
@WileyLifeSci
#PlantSci #JIPB #plant #medicine #botany

🧪Phillyrin is a unique #antiviral lignan with potent anti-#flu activity only found in Forsythia suspensa.
Wang et al. reveal key steps in its #biosynthesis, bringing us one step closer to a valuable #drug.
🔗https://doi.org/10.1111/jipb.70216
@WileyLifeSci
#PlantSci #JIPB #plant #medicine #botany

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

🍅It's #TomatoTuesday on Thursday!
🍅This time,🍅we join🍅Chen et al. as they investigate the #biosynthesis, regulation, and metabolic #engineering of #antifungal, #antibacterial,🍅and #anticancer compounds in #tomato.🍅
🍅 https://doi.org/10.1111/jipb.70077
@WileyLifeSci
#PlantSci #botany

🍅It's #TomatoTuesday on Thursday!
🍅This time,🍅we join🍅Chen et al. as they investigate the #biosynthesis, regulation, and metabolic #engineering of #antifungal, #antibacterial,🍅and #anticancer compounds in #tomato.🍅
🍅 https://doi.org/10.1111/jipb.70077
@WileyLifeSci
#PlantSci #botany

Need a little mid-week magic?🪄
🌱Well, we're #plant #scientists, so you're getting the "Magic #Methyl Effect."🧪

Li et al. explore key factors in the #biosynthesis of irregular terpenes--and more! Get a pre-pub sneak peek here! ⬇️

https://doi.org/10.1111/jipb.70048
@WileyLifeSci #botany

Need a little mid-week magic?🪄
🌱Well, we're #plant #scientists, so you're getting the "Magic #Methyl Effect."🧪

Li et al. explore key factors in the #biosynthesis of irregular terpenes--and more! Get a pre-pub sneak peek here! ⬇️

https://doi.org/10.1111/jipb.70048
@WileyLifeSci #botany

🎃 Have you picked your Halloween costume? 🎃 And more importantly, have you submitted your papers to our upcoming special issue on Advances in Plant Natural Products: #Biosynthesis, #Bioengineering, and Applications.

https://jipb.net/EN/news/news863.shtml

#PlantScience #medicine #food #beauty #agriculture #botany #SynBio

A mystery 30+ years in the making!

In this #OpenAccess Brief Report, Wu et al. describe a novel physiological function of the #Arabidopsis
PPRD1 in #brassinosteroid #biosynthesis, and new possibilities for alternative #steroid reductases involved in steroid #metabolism.

🌱 https://doi.org/10.1111/jipb.70022

#PlantSci

A mystery 30+ years in the making!

In this #OpenAccess Brief Report, Wu et al. describe a novel physiological function of the #Arabidopsis
PPRD1 in #brassinosteroid #biosynthesis, and new possibilities for alternative #steroid reductases involved in steroid #metabolism.

🌱 https://doi.org/10.1111/jipb.70022

#PlantSci

A mystery 30+ years in the making!

In this #OpenAccess Brief Report, Wu et al. describe a novel physiological function of the #Arabidopsis
PPRD1 in #brassinosteroid #biosynthesis, and new possibilities for alternative #steroid reductases involved in steroid #metabolism.

🌱 https://doi.org/10.1111/jipb.70022

#PlantSci

Genetic and biochemical insights into siderophore biosynthesis in the marine fish pathogen Tenacibaculum maritimum

Identification of the gene cluster…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bacterialgenetics #Biosynthesis #Desferrioxamine #HumanitiesandSocialSciences #Ironacquisition #Marinesiderophores #Metabolicpathways #Metals #multidisciplinary #nTenacibaculummaritimumn #Naturalproducts #Pathogens #Science #Tenacibaculosis
https://www.newsbeep.com/us/22444/

Genetic and biochemical insights into siderophore biosynthesis in the marine fish pathogen Tenacibaculum maritimum

Identification of the gene cluster…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bacterialgenetics #Biosynthesis #Desferrioxamine #HumanitiesandSocialSciences #Ironacquisition #Marinesiderophores #Metabolicpathways #Metals #multidisciplinary #nTenacibaculummaritimumn #Naturalproducts #Pathogens #Science #Tenacibaculosis
https://www.newsbeep.com/us/22444/

Genetic and biochemical insights into siderophore biosynthesis in the marine fish pathogen Tenacibaculum maritimum

Identification of the gene cluster…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bacterialgenetics #Biosynthesis #Desferrioxamine #HumanitiesandSocialSciences #Ironacquisition #Marinesiderophores #Metabolicpathways #Metals #multidisciplinary #nTenacibaculummaritimumn #Naturalproducts #Pathogens #Science #Tenacibaculosis
https://www.newsbeep.com/us/22444/

Genetic and biochemical insights into siderophore biosynthesis in the marine fish pathogen Tenacibaculum maritimum

Identification of the gene cluster…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bacterialgenetics #Biosynthesis #Desferrioxamine #HumanitiesandSocialSciences #Ironacquisition #Marinesiderophores #Metabolicpathways #Metals #multidisciplinary #nTenacibaculummaritimumn #Naturalproducts #Pathogens #Science #Tenacibaculosis
https://www.newsbeep.com/us/22444/

Shoot branching is an important #agronomic trait that impacts #plant architecture and #crop productivity.
Liu et al. report that the CsphyB–CsPIF4–CsBRC1 module regulates #ABA #biosynthesis and axillary bud outgrowth in #cucumber
https://doi.org/10.1111/jipb.13947
@wileyplantsci
#JIPB #botany

Shoot branching is an important #agronomic trait that impacts #plant architecture and #crop productivity.
Liu et al. report that the CsphyB–CsPIF4–CsBRC1 module regulates #ABA #biosynthesis and axillary bud outgrowth in #cucumber
https://doi.org/10.1111/jipb.13947
@wileyplantsci
#JIPB #botany

Shoot branching is an important #agronomic trait that impacts #plant architecture and #crop productivity.
Liu et al. report that the CsphyB–CsPIF4–CsBRC1 module regulates #ABA #biosynthesis and axillary bud outgrowth in #cucumber
https://doi.org/10.1111/jipb.13947
@wileyplantsci
#JIPB #botany

Recent studies explore a novel approach to control parasitic #plants by manipulation rather than #biosynthesis of #strigolactone exudation.
Learn more about this potential #CropScience breakthrough in a new #JIPB commentary.🔓⬇️
https://doi.org/10.1111/jipb.13937
@wileyplantsci
#PlantSci #botany

Recent studies explore a novel approach to control parasitic #plants by manipulation rather than #biosynthesis of #strigolactone exudation.
Learn more about this potential #CropScience breakthrough in a new #JIPB commentary.🔓⬇️
https://doi.org/10.1111/jipb.13937
@wileyplantsci
#PlantSci #botany

Most #biosynthetic gene clusters remain uncharacterized. @marnixmedema @gillesvanwezel &co integrate #GRN analysis & global expression data to identify desJGH as an operon essential for #biosynthesis of #desferrioxamineB in Streptomyces @PLOSBiology https://plos.io/43UVUPB

Cai et al. shine a light on #chloroplast-produced ROS #biosynthesis in #plant #immunity, with new findings that HHL1 modulates AvrRpt2-triggered immunity by regulating ROS homeostasis in a light intensity-dependent manner.
https://doi.org/10.1111/jipb.13929
@wileyplantsci
#PlantSci #JIPB #botany

Cai et al. shine a light on #chloroplast-produced ROS #biosynthesis in #plant #immunity, with new findings that HHL1 modulates AvrRpt2-triggered immunity by regulating ROS homeostasis in a light intensity-dependent manner.
https://doi.org/10.1111/jipb.13929
@wileyplantsci
#PlantSci #JIPB #botany

3-Jun-2025
Two plant species invent the same chemically complex and medically interesting substance
The elucidation of the biosynthetic pathway of #ipecacuanha #alkaloids shows how two distantly related plant species could develop the same substance independently

https://www.eurekalert.org/news-releases/1085960 #science #plants #bioactives #biosynthesis #evolution #plantPhysiology

Biosynthesis of ascorbic acid in animals and plants
Only humans cannot synthesize ascorbic acid, but plants and animals are very good at this task. In plants, biosynthesis begins with D-glucose, D-fructose is obtained, after D-mannose, from which, through other processes, ascorbic acid is obtained.
In animals, this process occurs differently, everything starts with D-glucose and ends with ascorbic acid.

#ascorbicacid #biochemistry #vitaminc #Biosynthesis

New publication: Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels-Alder Reaction as the Key Step in Lugdunomycin Biosynthesis. #bacteria #biosynthesis #chemicalreactions #genetics
https://doi.org/10.1021/jacs.5c01883

Mapping the #yerba_mate #genome reveals surprising facts about the #evolution of #caffeine.

#Ilex #genome_duplication #biosynthesis

https://phys.org/news/2025-02-yerba-genome-reveals-facts-evolution.html

Mapping the #yerba_mate #genome reveals surprising facts about the #evolution of #caffeine.

#Ilex #genome_duplication #biosynthesis

https://phys.org/news/2025-02-yerba-genome-reveals-facts-evolution.html

Mapping the #yerba_mate #genome reveals surprising facts about the #evolution of #caffeine.

#Ilex #genome_duplication #biosynthesis

https://phys.org/news/2025-02-yerba-genome-reveals-facts-evolution.html