#proteinengineering — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #proteinengineering, aggregated by home.social.
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⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?
🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling
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⚛️ Could life itself be a quantum phenomenon disguised as biology?
🔗 Quantum Biology Using Ultrafast Integrative and Molecular Engineering Tools: A Perspective. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0024
📚 CSBJ Quantum Biology and Biophotonics: https://spj.science.org/journal/csbj/qbio
#QuantumBiology #QuantumPhysics #MolecularBiology #ProteinEngineering #Biophysics #Biochemistry #Bioinformatics #SystemsBiology #MolecularDynamics #Lifesciences
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How I Built a Machine Learning Tool to Predict Drug Manufacturing Failures
A bioprocess engineer's journey into machine learning and why the pharmaceutical industry desperately needs this bridge When I tell people I work in bioprocess engineering, I usually get blank stares. When I explain that I help manufacture proteins in giant tanks for therapeutic use, the response is often: "Oh, like brewing beer?" Not quite. But close enough. What I don't usually mention is that I've been teaching myself machine learning on nights and weekends. Not because it's trendy, but […] -
From Bioreactors to AI: How I Built a Machine Learning Tool to Predict Drug Manufacturing Failures
*A bioprocess engineer's journey into machine learning—and why the pharmaceutical industry desperately needs this bridge* --- When I tell people I work in bioprocess engineering, I usually get blank stares. When I explain that I help manufacture proteins in giant tanks for therapeutic use, the response is often: "Oh, like brewing beer?" Not quite. But close enough. The $50 Million Problem Nobody Talks About What I don't usually mention is that I've been teaching myself machine learning […] -
From Bioreactors to AI: How I Built a Machine Learning Tool to Predict Drug Manufacturing Failures
*A bioprocess engineer's journey into machine learning—and why the pharmaceutical industry desperately needs this bridge* --- When I tell people I work in bioprocess engineering, I usually get blank stares. When I explain that I help manufacture proteins in giant tanks for therapeutic use, the response is often: "Oh, like brewing beer?" Not quite. But close enough. The $50 Million Problem Nobody Talks About What I don't usually mention is that I've been teaching myself machine learning […] -
🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?
🔗 STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #ProteinLanguageModels #Immunotherapy #ComputationalBiology #Bioinformatics #MachineLearning #Immunology #ProteinEngineering #TCR #HLA #DrugDiscovery #AI
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🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?
🔗 STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #ProteinLanguageModels #Immunotherapy #ComputationalBiology #Bioinformatics #MachineLearning #Immunology #ProteinEngineering #TCR #HLA #DrugDiscovery #AI
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Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological UniversityJoin us to work on AI for drug discovery!
See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/
#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=5646 -
⚛️ Is the secret to circular rare earth recovery hidden in molecular motion?
🔗 Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.005
📚 CSBJ: https://www.csbj.org/
#RareEarths #Lanmodulin #ComputationalBiology #Sustainability #CircularEconomy #RareEarthElements #MolecularDynamics #ProteinEngineering #MolecularModeling #MolecularSimulation
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Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological UniversityJoin us to work on AI for drug discovery!
See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/
#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=4463 -
Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological UniversityJoin us to work on AI for drug discovery!
See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/
#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=2489 -
🧩 The future of drug discovery may depend on how well we understand PROTAC-driven protein partnerships.
🔗 Mapping the energy landscape of PROTAC-mediated protein-protein interactions. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2023.02.049
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #PROTAC #DrugDiscovery #ComputationalBiology #ProteinEngineering #ProteinDegradation #Biopharma #MedicinalChemistry #TargetedTherapies #AIinBiotech #MolecularModeling
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Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological UniversityJoin us to work on AI for drug discovery!
See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/
#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=1789 -
Fully Funded PhD Scholarship (Spring/Fall 2026)
Nanyang Technological UniversityJoin us to work on AI for drug discovery!
See the full job description on jobRxiv: https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/
#deeplearning #drugdiscovery #largelanguagemodels #proteinengineering #RNAtherapeutics #ScienceJ...
https://jobrxiv.org/job/nanyang-technological-university-27778-fully-funded-phd-scholarship-spring-fall-2026/?fsp_sid=1768 -
🤖 How can artificial intelligence help us outsmart rapidly evolving viruses like H5N1?
🔗 AI-based antibody design targeting recent H5N1 avian influenza strains. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.026
📚 CSBJ: https://www.csbj.org/
#H5N1 #AIforHealth #AntibodyDesign #Biotech #ComputationalBiology #Influenza #AI4Biotech #GenerativeBiology #PandemicPrep #SyntheticBiology #ProteinEngineering #ComputationalBiology #DrugDiscovery
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🚀 What role does protein design play in advancing next-gen optogenetic tools?
🔗 Protein design accelerates the development and application of optogenetic tools. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.014
📚 CSBJ: https://www.csbj.org/
#Optogenetics #ProteinEngineering #Neuroscience #AlphaFold #ProteinDesign #SyntheticBiology
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🔬 New Review Published!
Explore the exciting world of enzymatic protein fusion—where we combine enzymes to enhance biological activity and precision. From biocatalysis to gene therapy and biosensing, fusion proteins are reshaping biotech innovation.
🧬 Read the full article: https://doi.org/10.1016/j.cis.2025.103473#FusionProteins #ProteinEngineering #EnzymeTechnology #SyntheticBiology #Biocatalysis #GeneTherapy #Biosensing #Bioengineering #Biotechnology #MolecularBiology #NextGenBiotech #ScienceMastodon
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🔬 New Review Published!
Explore the exciting world of enzymatic protein fusion—where we combine enzymes to enhance biological activity and precision. From biocatalysis to gene therapy and biosensing, fusion proteins are reshaping biotech innovation.
🧬 Read the full article: https://doi.org/10.1016/j.cis.2025.103473#FusionProteins #ProteinEngineering #EnzymeTechnology #SyntheticBiology #Biocatalysis #GeneTherapy #Biosensing #Bioengineering #Biotechnology #MolecularBiology #NextGenBiotech #ScienceMastodon
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🔬 New Review Published!
Explore the exciting world of enzymatic protein fusion—where we combine enzymes to enhance biological activity and precision. From biocatalysis to gene therapy and biosensing, fusion proteins are reshaping biotech innovation.
🧬 Read the full article: https://doi.org/10.1016/j.cis.2025.103473#FusionProteins #ProteinEngineering #EnzymeTechnology #SyntheticBiology #Biocatalysis #GeneTherapy #Biosensing #Bioengineering #Biotechnology #MolecularBiology #NextGenBiotech #ScienceMastodon
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CW: Long Hashtag List for the Life Sciences
Life Sciences Hashtags
• Animal Behaviour
#AnimalBehavior #AnimalBehaviour #AnimalCognition #AnimalPsychology #AnimalResearch #AnimalSocieties #AnimalStudies #BehavioralEcology #BehaviouralEcology #BehavioralScience #BehaviouralScience #CameraTraps #ComparativeCognition #CriticalAnimalStudies #Learning #Memory #PositiveReinforcement #Sociobiology #TrailCam• Astrobiology
#AlienLife #Astrobiology #Biosignatures #Cryosphere DeepIce #EarthScience #Exoplanets #GeoScience #Habitability #Karst #MicroHabitats #OceanWorlds #OriginOfLife #PlanetaryCaves #PlanetaryScience• Behaviour Science
#AnthroZoology #Behavior #Behaviour #Behaviour2023 #BehavioralScience #BehaviouralScience #Biopsychology #CognitiveDevelopment #ComparativeCognition #DevelopmentalPsychology #Ethology #Learning #Memory #Neuroethology #PhilosophyOfMind #PleasureActivism #Psychology #SelfOrganisation #SelfOrganization #SocialNetwork• Biochemistry | Group: @biochemistry
#Actin #AminoAcids #Biochemical #Biochemistry #Catalyst #Catalysis #DNA #Enzyme #Enzymes #Hormones #IonChannels #Kinetics #Metabolism #Metabolomics #mRNA #Peptides #Polymer #Protein #Proteins #RNA• Bioinformatics | Group: @bioinformatics
#BigData #Bioinformatics #RStats• Biology | Group: [email protected]
#Biochemistry #Biology #Biomes #Botany #Ecology #Ecosystem #Evolution #Genetics #Habitat #LifeCycle #MarineBiology #Microbiology #Zoology• Biomaterial Science
#Biofilm #Biofilms #Biologics #Biomaterials #Biotechnology #MaterialsScience #Nanotechnology #SustainableDesign #SyntheticBiology• Biomedical Science
#Biomedical #BiomedicalEngineering #BiomedicalScience #NetworkMedicine #SystemsBiology• Botany
#Botany #Botanical #Botanist #FloraIncognita #Florespondence IAmABotanist #Phenology #PlantBiology #PlantCells #PlantID #PlantIdentification• Cell Biology | Group: @cellbiology
#CellBiology #CellDivision #CellMigration #Chloroplast #Cilium #Cytoskeleton #EndoplasmicReticulum #Eukaryotes #Golgi #Lipids #Macrophages #Membrane #Membranes #Microtubules #Mitochondria #Nucleus #Organelle #Organoids #Ribosome #SingleCell• Developmental Biology
#ChildDevelopment #Connectome #Connectomics #DevelopmentalBiology #Embryology #Embryos #EvoDevo #GeneRegulation #Pregnancy #Proteomics #ReproSci #SexDet #StemCells #Transcriptomics• Ecology | Group: @ecology
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#Beetles #Bugs #Coleoptera #Crustaceans #Entomologia #Entomology #Hemiptera #Hymenoptera #iNaturalist #Insect #Insects #InsectPhotography #Invertebrates #Isopods #Lepidoptera #Metamorphosis #Orthoptera #Pupa #Taxonomy• Genetics
#BasePair #CellDivision #Chromosome #Chromosomes #Clone #Epigenetics #DNA #Gene #GeneExpression #GeneRegulation #GeneticallyModified #Genetics #Genome #Genomics #GMO #Meiosis #Mitosis #Mutation #RNAseq #Telomeres #Variants• Immunology
#Antibodies #Antibody #Antigen #AutoImmune #BCells #Immune #ImmuneSystem #Immunity #ImmunoCompromised #Immunology #ImmunoTherapy #Interferon #Macrophages #Monoclonal #MonoclonalAntibodies (#mAbs) #Neutrophils #TCell #Vaccinated #Vaccine #Viralimmunology• Marine Science
#Acidification #Algae #Aquatic #Cetaceans #Coral #CoralBleaching #CoralReefs #DeepSea #Diatoms #Estuary #Eutrophication #Kelp #KelpForest #MarineBiology #MarineLife #MarineMammals #MarineScience #MarineTaxonomy #Oceanography #Oceans #OceanWarming #Phytoplankton #Reefs #SeaBed #SeaFloor #SeaGrass #Seaweed #ScubaDiving #Snorkeling #UnderWaterPhotography #Zooplankton• Microbiology | Group: @microbiology
#Antibiotics #AntiMicrobial #AntiMicrobialResistance (#AMR) #Bacteria #Bacterial #Bacteriophage #Bacteriology #Cilia #Microbes #Microbial #MicrobialEcology #Microbiology #Microbiome #Microbiota #MicroOrganisms #Phage #Protists#EColi #Legionella #Pseudomonas #Salmonella #Streptomyces
• Molecular Biology | Group: @molecularbiology
#Biophysics #CellBiology #MolecularBiology #MolecularEvolution #ProteinEngineering #ProteinStructure #Proteomics #StructuralBiology• Mycology | Group: @mycology
#Fungi #Fungiverse #Mushrooms #Mycelium #Mycologists #Mycology #Mycophile #Spores #Sporespondence• Ornithology | Group: @ornithology
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#AntiViral #AvianFlu #Bacteriophage #BirdFlu #CoronaVirus #COVID #COVID19 #GiantViruses #HIV #InfectiousDisease #Ebola #Measles #Phage #SARS #SARSCoV2 #Vaccine #Vaccines #ViralLoad #Viralimmunology #ViralPersistence #Variants #Virology #Virome #Virus #Viruses• Zoology
#Animals #Biology #Zoologist #Zoology(Click to access Scientists in the Formal, Natural & Social Sciences)
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01/2023 Issue ➡️ http://bit.ly/3CMpyKi
On the cover: Engineered bacteria expressing a designed single-chain IL-10 prevent severe inflammation in Pseudomonas aeruginosa lung infection
Luis Serrano lab, CRG
#proteinengineering #immunomodulation #synbio #SystemsBiology -
Computer-designed single-chain IL-10 molecules expressed in the mouse lung by an engineered attenuated bacterium have an anti-inflammatory effect on #Pseudomonas aeruginosa lung #infection ➡️ http://bit.ly/3GiCAQz
Luis Serrano lab, CRG
#proteinengineering #immunomodulation
#SynBio #SyntheticBiology -
Excited to share my very first paper which was just published in #JACS:
https://pubs.acs.org/doi/10.1021/jacs.2c10673
In this work carried out during my PhD together with Jamie Klein, Tomasz Kaminski, and Pierre-Yves Colin in the Hollfelder Lab at #UniversityofCambridge we evolve a #phosphotriesterase with a new, metal-independent mechanism by using droplet #microfluidics.
Comments and feedback welcome! A thread: (1/6)
#EnzymeEngineering #ProteinEngineering #EnzymeMechanism #DirectedEvolution #Bioremediation
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re-#Introduction with new handle after move to fediscience.org #ScienceMastodon
Hi, I'm Sven, a #structural #biochemist who recently moved from #Dundee, Scotland to #Boston, MA to start a #postdoc in the Brown lab at #HarvardMedicalSchool.
My broad interests are #structuralbiology
#cryoEM
#cilia
#ubiquitin
#biophysics
#proteinfolding #proteinengineering
#methods
#CellBiologyLooking to build a network on here! 🤝 😄