#antibiotics — Public Fediverse posts

As antibiotic resistance grows, researchers are turning to copper as a weapon against bacterial infections

https://phys.org/news/2026-09-antibiotic-resistance-copper-infections.html

#science #health #antibiotics

⚛️ Would today’s antibiotics still work if bacterial biology were flipped at the molecular level?

🔗 Molecular Dynamics Simulations Demonstrate Reduced Antibiotic Affinity to Mirror Bacterial Targets. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0198

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#MolecularDynamics #Antibiotics #Biosecurity #ComputationalBiology #SyntheticBiology #DrugDiscovery #AntimicrobialResearch #ComputationalChemistry

💊 If antibiotic courses tend to be longer (and thus risker) than necessary, whose responsibility is it to shorten them?

🏥 I argue it's not just doctors that have duties to minimize and shorten antibiotic courses. Why? Because antibiotic prescriptions are influenced by events that occur both before and after a doctor decides whether to order #antibiotics.

📄 Now in The American Journal of #Bioethics: https://doi.org/10.1080/15265161.2026.2709547

🎙️ Free audio and text…

https://byrdnick.com/archives/31046/upon-reflection-ep-17-two-sides-of-shorter-is-better-antibiotic-stewardship

Within-patient gene transfer between transiently and chronically infecting bacteria causes extreme antibiotic resistance during lung infections

Murray, C. J. L. et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet…
#NewsBeep #News #Health #antibiotics #Clinicalmicrobiology #GB #general #InfectiousDiseases #LifeSciences #MedicalMicrobiology #Microbiology #Parasitology #UK #UnitedKingdom #virology
https://www.newsbeep.com/uk/710418/

New publication: Inducible #CRISPRi enables efficient and high-fidelity #genome editing in #Streptomyces. #antibiotics
https://doi.org/10.1093/nar/gkag560

New publication: Inducible #CRISPRi enables efficient and high-fidelity #genome editing in #Streptomyces. #antibiotics
https://doi.org/10.1093/nar/gkag560

New publication: Inducible #CRISPRi enables efficient and high-fidelity #genome editing in #Streptomyces. #antibiotics
https://doi.org/10.1093/nar/gkag560

New publication: Inducible #CRISPRi enables efficient and high-fidelity #genome editing in #Streptomyces. #antibiotics
https://doi.org/10.1093/nar/gkag560

Now in Chem Sci! 🎉
We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

https://doi.org/10.1039/D6SC00250A

I am very excited and proud that Julia Pols very successfully completed their PhD in our group. They wrote an excellent PhD thesis and engaged in exciting in-depth discussions with all the opponents during the PhD defense. (1/4)
#PhDone #PhD #ProudPI #Antibiotics #ChemBio

"Rapid Antibiotic Discovery using a Direct-to-Biology Approach"

Storm van der Voort from the group of Hermen Overkleeft and our group at the @LED3hub presented his exciting research into efficiently finding new antibacterially active #CovalentInhibitors using a direct-to-biology approach and into finding their targets using residue-specific chemoproteomics with the isoDTB-ABPP technology at #NWOCHAINS.

#Bacteria #Antibiotics #Chemistry #ChemBio #ChemicalProteomics #D2B

New paper out! Bioactive molecules unearthed by terabase-scale long-read sequencing of a soil metagenome | Nature Biotechnology

https://www.nature.com/articles/s41587-025-02810-w

#soilmicrobiome #antibiotics #Bioinformatics #nanopore #ont #OpenAccess #naturebiotechnology #naturebiotech

During her work at Rutgers University microbiologist Elizabeth Bugie (1920-2001) was involved in the discovery of streptomycin, the first antibiotic effective against tuberculosis. While her boss received the Nobel Prize for this discovery, she wasn’t mentioned. Honouring her work on the discovery and evaluation of antibiotics, DSMZ researchers named the strain Streptomyces bugieae (DSM 41528) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #streptomyces #microbiology #antibiotics

During her work at Rutgers University microbiologist Elizabeth Bugie (1920-2001) was involved in the discovery of streptomycin, the first antibiotic effective against tuberculosis. While her boss received the Nobel Prize for this discovery, she wasn’t mentioned. Honouring her work on the discovery and evaluation of antibiotics, DSMZ researchers named the strain Streptomyces bugieae (DSM 41528) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #streptomyces #microbiology #antibiotics

During her work at Rutgers University microbiologist Elizabeth Bugie (1920-2001) was involved in the discovery of streptomycin, the first antibiotic effective against tuberculosis. While her boss received the Nobel Prize for this discovery, she wasn’t mentioned. Honouring her work on the discovery and evaluation of antibiotics, DSMZ researchers named the strain Streptomyces bugieae (DSM 41528) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #streptomyces #microbiology #antibiotics

During her work at Rutgers University microbiologist Elizabeth Bugie (1920-2001) was involved in the discovery of streptomycin, the first antibiotic effective against tuberculosis. While her boss received the Nobel Prize for this discovery, she wasn’t mentioned. Honouring her work on the discovery and evaluation of antibiotics, DSMZ researchers named the strain Streptomyces bugieae (DSM 41528) after her.

#herstory #HonoringWomenInSTEM #WomenInScience #streptomyces #microbiology #antibiotics

Excited to see Julia Pols presenting their research in our group at #NWOCHAINS2024. They did a great job in giving a clear presentation on their PhD project on identifying new ligandable cysteines as antibacterial targets against MRSA. #proudPI #ChemBio #Antibiotics

Honestly, i'd never heard of spectinamides!
#IDMastodon #antibiotics #TB

A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides https://elifesciences.org/articles/96190
1/2

Mum thought she had chest infection - months later she was diagnosed with 'first cancer of its kind in world'
https://www.msn.com/en-gb/health/other/mum-thought-she-had-chest-infection-months-later-she-was-diagnosed-with-first-cancer-of-its-kind-in-world/ar-BB1k5Fzj?ocid=winp2fptaskbarhover&cvid=e4383d23362f4cd99697124ecea0970c&ei=12

#Cancer
#Chest
#Ovaries
#FluidOnTheLung
#ChestInfection
#Antibiotics
#Appendix
#Bowel
#Rectum
#GobletCell
#UniversalCredit
#Donations

Ants treat wounds with antibiotics: academic: https://www.nature.com/articles/s41467-023-43885-w popular: https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/ant-antibiotics/

#nature #entomology #ants #wounds #woundcare #antibiotics #eriktrank #luciekesner#joanitoliberti #quentinhelleu #adriacleboeuf #andreidascalu #douglasbsponsler #fumikaazuma #evanpeconomo #patricewaridel #philippengel #thomasschmitt #laurentkeller #UniversityofWürzburg #UniversityofWürzburg

Researchers at Sandia National Laboratories have combined earlier work on painless #microneedles with #nanoscale #sensors to create a wearable sensor patch capable of continuously monitoring the levels of one of these #antibiotics.
#Engineering #Nanotechnology #Medical #Microbiology
https://www.sflorg.com/2023/10/eng10032301.html

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci

Katherine Duncan from Strathclyde University:

Linking genes and metabolites for informed antibiotic discovery

#jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

@LBNLBioSci