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#antibiotics — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #antibiotics, aggregated by home.social.

  1. ⚛️ Would today’s antibiotics still work if bacterial biology were flipped at the molecular level?

    🔗 Molecular Dynamics Simulations Demonstrate Reduced Antibiotic Affinity to Mirror Bacterial Targets. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0198

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MolecularDynamics #Antibiotics #Biosecurity #ComputationalBiology #SyntheticBiology #DrugDiscovery #AntimicrobialResearch #ComputationalChemistry

  2. Honestly, i'd never heard of spectinamides!
    #IDMastodon #antibiotics #TB

    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides elifesciences.org/articles/961
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  3. Helicobacter pylori causes gastric #ulcer leading to #cancer. (800000 deaths/year). Treatment is #antibiotics and a bismuth compound. Pepto-Bismol which treats upset stomach also contains bismuth.

    Here, the team show H. pylori blebs out vesicles with bismuth to stay alive in the stomach. Quite an elegant study on defense mechanisms in #bacteria (h/t TWiM)

    #microbiology #mBio

    journals.asm.org/doi/full/10.1