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#antibiotics — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #antibiotics, aggregated by home.social.

  1. Now in Chem Sci! 🎉
    We investigated how #enzymes in the #nonribosomal #biosynthesis of life-saving #peptide #antibiotics can be engineered.
    Assuming that #promiscuity serves as a springboard for #evolution, we measured the specificity profiles of hundreds of mutants. The results revealed remarkable shifts in substrate specificity in multiple directions, highlighting the evolutionary potential of these enzymes and leading the way for engineering antibiotic biosynthesis.

    doi.org/10.1039/D6SC00250A

  2. I am very excited and proud that Julia Pols very successfully completed their PhD in our group. They wrote an excellent PhD thesis and engaged in exciting in-depth discussions with all the opponents during the PhD defense. (1/4)
    #PhDone #PhD #ProudPI #Antibiotics #ChemBio

  3. "Rapid Antibiotic Discovery using a Direct-to-Biology Approach"

    Storm van der Voort from the group of Hermen Overkleeft and our group at the @LED3hub presented his exciting research into efficiently finding new antibacterially active #CovalentInhibitors using a direct-to-biology approach and into finding their targets using residue-specific chemoproteomics with the isoDTB-ABPP technology at #NWOCHAINS.

    #Bacteria #Antibiotics #Chemistry #ChemBio #ChemicalProteomics #D2B

  4. Excited to see Julia Pols presenting their research in our group at #NWOCHAINS2024. They did a great job in giving a clear presentation on their PhD project on identifying new ligandable cysteines as antibacterial targets against MRSA. #proudPI #ChemBio #Antibiotics

  5. Lolamicin: The Selective antibiotic against Gram-negative infections that spares gut microbiome  
    Current antibiotics used in clinical practice, in addition to neutralising target pathogens also harm healthy bacteria in the gut............
    #Antibiotics #Gramnegativebacteria #GutBacteria #Lolamicin #microbiome #NewsinBrief
    SCIEU Team

    scientificeuropean.co.uk/medic

  6. Researchers at Sandia National Laboratories have combined earlier work on painless #microneedles with #nanoscale #sensors to create a wearable sensor patch capable of continuously monitoring the levels of one of these #antibiotics.
    #Engineering #Nanotechnology #Medical #Microbiology
    sflorg.com/2023/10/eng10032301

  7. Katherine Duncan from Strathclyde University:

    Linking genes and metabolites for informed antibiotic discovery

    #jgi2023 #actinomycetes #streptomyces #antibiotics #jgi

    @LBNLBioSci

  8. AGATHOKAKOLOGICAL

    I learned a new word.

    Keynote by Dianne Newman from CalTech at #JGI2023

    (besides fancy words also covering new phenazine "antibiotics" and the pathways that make them)

    @LBNLBioSci #phenazine #metabolites #Pathways #antibiotics