#regeneration — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #regeneration, aggregated by home.social.
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Loca'Terre - Communectez-vous ! https://vimeo.com/147290335 #commons #uusitalous #p2p #neweconomy #regeneration #dework #cosmolocal
Loca'Terre - Communectez-... -
Regen Melbourne
I can’t believe I have not written about Regen Melbourne before. I have been loosely involved with them from the beginning and the crafting of their original co-created vision statement, based on Kate Raworth’s Doughnut Economics model. I have also had the pleasure of being part of some of their workshops, and they have also been of great help and support with my own personal regeneration project.
Over the years, Regen Melbourne’s work has steadily evolved and now coalesces around three key Earthshots. An Earthshot is a declaration of intent to solve complex social and ecological challenges. Earthshots recognise that social and ecological regeneration are inseparable. They set an ambition of possibility, coherence of a collective response, and agitation of the conditions we operate within. Earthshots are whole-of-city in scope, long-term in commitment, and open to many entry points.
Each Earthshot has six key qualities.
Wildly Ambitious
Because the scale of the challenges demand it. We are all invested in the social and ecological future of this place.
Systems-oriented
Looking at the conditions we need not just outputs. Oriented towards multi-benefits not single solutions.
Whole-of-city
No one organisation can own the scope of the Earthshot. We are interconnected, so too must our response be.
Coherence, not consensus
There is no blueprint. Forward-leaning action looks like smart collaboration, not waiting for everyone to agree.
Long-term and open
Committed to building broad support over time. An Earthshot is a platform for entry points, not a closed project.
Of and for Melbourne
These Earthshots are in service to place. They build on what makes this city thrive and centre care for our future.
The current Earthshots they are focussing on are:
Swimmable Birrarung
A thriving and swimmable Birrarung, from source to sea
300,000 Streets
A city of participatory and truly liveable streets
Nourished Neighbourhoods
A network of resilient local food economies across our cityYou can find a load more about all of this on their website but what caught my eye recently was this particular article, The Power of Participation: Strengthening the civic muscle of Greater Melbourne. [LINK] The author, Joel Backwell, covers a lot of ground in this post talking about Participatory Urbanism in Melbourne, from “what we are seeing” now, to “where to from here”. For anyone living in Melbourne it’s a great snapshot of some of the wonderful projects and orgs operating on the ground and the work they are doing. The article asks the big questions about participation as well as explaining its importance. Something I have done in previous posts: HERE and HERE
#Biodiversity #Environment #Melbourne #OurWonderfulGreenFuture #Participation #ParticipatoryUrbanism #Regeneration #RegenMelbourne #SolarPunk #StrongTowns #sustainability #Urbanism
“What we are interested in is how all this participation comes together, in service of Greater Melbourne. How intentional must we be in directing this participation towards influencing and shaping power? Or is it enough to just create opportunities for people to come together to discuss what matters to them and their neighbourhoods, and then let a thousand flowers bloom? Can we expect that participation, in response to societal and environmental challenges, will organically scale up to political action? Or will it require organisations like Regen Melbourne to help join the dots, bring these spheres of activity together and build new spaces and institutions for collaboration and collective decision-making at a city scale?“
I’ll wrap this up here because I hope I’ve given enough reasons to go and read the post and check out more about what Regen Melbourne is doing in general on their website here: https://regen.melbourne They have their fingers in a lot of pies, so for anyone interested in Climate Change, Social Justice, or Regeneration, you will find loads of stuff to dive into: Climate Change Exchange – Democracy Beyond the Ballot Box – Connected Corridors – School Streets
Other links
You can follow The REGEN Gazette here: https://regen.melbourne/the-gazette
The People’s Plan for Footscray https://peoplesplanfootscray.net/
McKinnon and Foundations for Tomorrow https://foundationsfortomorrow.org
Doing Co: https://doingco.org/ -
RE: https://scicomm.xyz/@mustapipa/117137230074004940
If economics can be said to speak, it needs to shout LOUDLY about proper green regeneration (rather than plant-a-tree make-work): “Scientists found that natural #forest regeneration delivered substantial carbon and #biodiversity benefits and could be up to 96% cheaper than traditional tree-planting programs.” 🌳🌲🌴🎄
Fabulous news - thanks so much for sharing! 😀🙏🏻
#regeneration #forestRegeneration #costBenefit #carbonSink #RoI
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How Elephant and Castle risks becoming London’s gentrification ‘patient zero’
By Phillip Inman and Sarah ButlerNew £500m town centre welcomes its first tenant this month, but displaced traders say promises that they could return have been broken
#Gentrification #London #Hospitalityindustry #Retailindustry #Housing #Regeneration #Communities #Society #UKnews #Cities #Business #TheGuardian #PhillipInman #SarahButler
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This morning, we had the privilege of educating young people on proper waste management and environmental responsibility. By empowering the next generation with sustainable habits, we are building cleaner communities and protecting our environment for the future. Every lesson shared today is a step toward lasting positive change.
#climate #environment #ecosystem #climatechange #nature #conservation #biodiversity #regeneration #ecology #afforestation #wastemanagement #sanitation #climatecrisis -
Beyond Economics: A New Lens on Climate Resilience
Every so often a new report comes out that reminds us all the climate crisis is a health crisis.
#ClimateChange #Environment #OurWonderfulGreenFuture #OWGF #Regeneration #StrongTowns #Urbanism
https://owgf.org/2026/06/10/beyond-economics-a-new-lens-on-climate-resilience/ -
Regeneration (ecology) (Ecosystems 🏞️)
In ecology regeneration is the ability of an ecosystem – specifically, the environment and its living population – to renew and recover from damage. It is a kind of biological regeneration. Regeneration refers to ecosystems replenishing what is being eaten, disturbed, or harvested. Regeneration's biggest force is photosynth...
https://en.wikipedia.org/wiki/Regeneration_(ecology)
#Regeneration #Ecosystems #Superorganisms #SystemsEcology #BiologicalSystems
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Regeneration (ecology) (Ecosystems 🏞️)
In ecology regeneration is the ability of an ecosystem – specifically, the environment and its living population – to renew and recover from damage. It is a kind of biological regeneration. Regeneration refers to ecosystems replenishing what is being eaten, disturbed, or harvested. Regeneration's biggest force is photosynth...
https://en.wikipedia.org/wiki/Regeneration_(ecology)
#Regeneration #Ecosystems #Superorganisms #SystemsEcology #BiologicalSystems
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Spirituality & Religious Studies @spiritualityreligiousstudies.wordpress.com@spiritualityreligiousstudies.wordpress.com ·Eternal Security
This is also known as “once saved, always saved.” It’s the belief giving Christian believers with an absolute assurance of their final salvation.
Its development, especially in Protestantism, has given rise to a plethora of different interpretations. Especially when defining aspects of determinism, libertarian free will & the significance of personal perseverance.
In the early 5th century, Augustinian soteriology views of predestination by predetermination came about, they didn’t validate Eternal Security. Soteriology is the doctrine of salvation.
By the 16th century, this idea became meshed into the theology of John Calvin & other reformers. Calvinist circles initially embraced Eternal Security under the name of “perseverance of the saints.” Eventually, the name became a synonym of the Calvinist doctrine of perseverance independent of its practical interpretations.
Then in the early 20th century, Eternal Security started to become a defining doctrine of Southern Baptist traditionalism. Around the same time, it also became a part of Plymouth Brethren theology. In this, the 2 forms represents its main form today.
In the 1980s, the Free Grace movement voiced that Eternal Grace was independent of the idea of the “Hyper-Grace” idea.
Eternal Security is based on the faith that the believer is an elect by divine determination. This is in Calvinist circles & has the minority worldview.
In some non-Calvinist circles & the prevailing worldview, Eternal Security is based on the faith that regeneration leads to unconditional perseverance & then salvation.
In other non-Calvinist circles & currently growing in the Free Grace views, Eternal Security is based on the faith that regeneration leads to salvation independent of perseverance.
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#16thCentury #1980s #5thCentury #Augustinians #Calvinist #Christian #Determinism #DivineDetermination #Early20thCentury #EternalSecurity #FreeGraceMovement #HyperGrace #JohnCalvin #LibertarianFreeWill #Perseverance #PerseveranceOfTheSaints #PlymouthBrethen #Predestination #Protestantism #Reformers #Regeneration #Salvation #Soteriology #SouthernBaptist #SouthernBaptistTraditionalism
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Native forest regeneration failure
Logging devastated Victoria’s native forests – and new research shows 20% has failed to grow back
"Following the end of native logging in Victoria on January 1 2024, the state’s majestic forests might be expected to regenerate and recover naturally. But our new research shows that’s not always the case. "
"These degraded areas no longer hold the value they once did and they cannot provide the same level of ecosystem services such as carbon storage, water purification, or habitat for wildlife."
"With no current government restoration plan, these landscapes will remain degraded indefinitely. Our research suggests leaving nature to its own devices would mean losing a fifth of the forests logged over the past 40 years. Bringing the trees back has multiple benefits and would be well worth the investment."
>>
https://theconversation.com/logging-devastated-victorias-native-forests-and-new-research-shows-20-has-failed-to-grow-back-254465>> original
A significant increase in forest regeneration failure following logging is driven by climatic and management factors
https://linkinghub.elsevier.com/retrieve/pii/S0301479725011454
#biodiversity #wildlife #NativeForests #LoggingImpacts #LoggingIndustry #extractivism #clearfelling #degradation #regeneration #failure #ClimateBreakdown -
Researchers Dumped Tons Of Coffee Waste Into A Forest. This Is What It Looks Like Now.
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https://www.upworthy.com/researchers-dumped-tons-of-coffee-waste-in-a-forest-ex1 <-- shared article
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https://doi.org/10.1002/2688-8319.12054 <-- shared paper
--#GIS #spatial #mapping #forest #waste #regeneration #coffee #biomass #forest #waterquality #soil #agroindustry #tropicalforest #recovery #CostaRica #change #soilnutrients #groundcover #understoryvegetation, #treeestablishment #canopycover #tree #vegetation #soil #carbon #nitrogen #fertility #phosphorous #forestsuccession #restoration
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Regeneration (ecology) (Ecosystems 🏞️)
In ecology regeneration is the ability of an ecosystem – specifically, the environment and its living population – to renew and recover from damage. It is a kind of biological regeneration. Regeneration refers to ecosystems replenishing what is being eaten, disturbed, or harvested. Regeneration's biggest force is photosynth...
https://en.wikipedia.org/wiki/Regeneration_(ecology)
#Regeneration #Ecosystems #Superorganisms #SystemsEcology #BiologicalSystems
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Regeneration (ecology) (Ecosystems 🏞️)
In ecology regeneration is the ability of an ecosystem – specifically, the environment and its living population – to renew and recover from damage. It is a kind of biological regeneration. Regeneration refers to ecosystems replenishing what is being eaten, disturbed, or harvested. Regeneration's biggest force is photosynth...
https://en.wikipedia.org/wiki/Regeneration_(ecology)
#Regeneration #Ecosystems #Superorganisms #SystemsEcology #BiologicalSystems
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Upon the event of my pathetically over-booked #apotheosis I #need to be addressed as #Dahl #E #Pardon.
It will streamline the new character sheet #regeneration #process considerably.
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"Multiphoton microscopy revealed that #tendon-like #collagenous tissue bridges residual tendon stubs in newts, but disorganized scar-like tissue filled the injured location in mice. These findings highlight the remarkable capacity of #newts to recover from tendon injury and confirm the utility of newts as a model to study tendon #regeneration."
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Our lab presentations at #SICB2023
Ranny’s talk: Comparative transcriptomics reveals sex-specific differences in #Platynereis dumerilii (Tomorrow, Jan 4th)Bria’s talk: The cost or payout of #regeneration on growth and sexual maturation in Platynereis dumerilii (Tomorrow, 4th)
Duygu’s talk: Single-cell transcriptomics reveal specific gut regions in a freshwater #annelid (Thursday, 5th)
Ryan’s poster: Automating design of #fluorescent in situ probes for big data sets (Friday, 6th)
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CW: Using Human Pluripotent Stem Cells to Create Human Skeletal Muscle Organoids for Repair and Regeneration
Skeletal #muscle is a type of tissue that makes up a large part of the human body. It is made up of many different cells that are able to contract and move. Skeletal muscle has the ability to #repair itself when it is damaged due to #aging, exercise, or diseases like #MuscularDystrophy. A small group of cells called #SatelliteCell s help with the repair process. Scientists have been trying to create models to study how #Skeletalmuscle develops and regenerates. Recently, they have been using human pluripotent #StemCell to create 3D models of skeletal muscle tissue. However, these models have not been able to recreate the full process of muscle regeneration. In this research paper, the authors introduce a new method of using human pluripotent stem cells to create 3D models of skeletal muscle tissue that can retain the ability to repair itself.
Over the past decades, scientists have used #animalmodel to study #muscleregeneration, which is regulated by #stemcell s. These animal models have been very helpful in understanding the mechanisms of muscle #regeneration, but they don't always accurately reflect the same range of diseases that humans experience. Therefore, researchers have suggested creating reliable in vitro models using human muscle cells. ( #hPSC s) could be used to create 3D human skeletal muscle #organoid s ( #hSkMO s) that contain sustainable #stemcell and distinct myofibers with the same proteins and structure as adult muscles. Previous approaches to skeletal muscle differentiation have been developed using 2D #culture systems, but these lack the natural environment and #StemCell niche that are necessary to model adult #myogenesis and muscle #regeneration.
#Stemcell s ( #SC s) can be used to repair damaged muscle tissue. They explain that SCs can be activated in response to muscle injuries and that other #cell types can contribute to the process of #myogenesis. The author then goes on to explain that #cytokine s, such as IL-4, can influence the #InflammatorySystem and promote SCs differentiation, which helps with muscle regeneration. While #organoid s generated from #hPSC s have potential, they do not fully replicate the in vivo native microenvironment. To address this, treat the #hSkMO s with extrinsic #cytokine s to promote #muscle #regeneration . #hSkMO s might then be used to study aspects of human muscle #biology and to identify novel #therapeutic candidates for muscle-wasting disorders.
To create a 3D structure of muscle tissue. They used #WNT activator and #BMP inhibitors at the beginning of the differentiation process to induce paraxial #mesodermal #cell s. They then added #FGF2 to the Matrigel to promote the 3D structure. #HGF and IGF1 were added later to accelerate the #myogenic specification and further #myofiber differentiation. They optimized the timing of the Matrigel embedding to day seven. After this, they observed #neuralcell s and withdrew FGF2 to focus on muscle tissue development. They then prolonged the HGF and IGF1 treatment to propagate #myogenic #progenitor s. They found that 62% of the #tissue was #skeletalmuscle tissue and that it contained PAX7+ #myogenic #stem / #progenitor cells, MYOD+ activated/committed #myoblast s, and MYOG+ #myocyte s. They also found that 31% of PAX7+/Ki67− and 29% of MYOD−/PAX7+ non-dividing quiescent SCs were present in the mature #hSkMO s. This indicates that the #hSkMO s were able to effectively recreate #embryo nic #myogenesis and have regenerative potential. Future studies using #singlecell #RNA sequencing may be necessary to further characterize the different types of cells in #hSkMO s.
The stepwise process to generate human skeletal muscle organoid s (hSkMOs) from human pluripotent stem cells (hPSCs)
The process begins with dissociating #hPSC s into #singlecell s and allowing them to form #embryoid bodies ( #EB s) in low-attachment V-shaped 96-well plates. Then, paraxial #mesodermal differentiation is promoted with #WNT activation, BMP inhibition, and FGF2 signaling. The expression of pluripotency markers OCT4 and NANOG decreases, and the expression of #mesoderm markers Brachyury, T-Box transcription factor 6 (TBX6), and mesogenin 1 (MSGN1) increases. To further characterize paraxial #mesoderm al differentiation, TBX6 is #immunostain ed. After paraxial #mesodermal induction, the #organoid s are embedded with growth factor-reduced Matrigel and transferred to a six-well plate on an orbital shaker. Growth factors are then added to the #myogenic specification media, and #hSkMO s are cultured until the day of analysis. The orbital shaker improves the viability, survival, and differentiation of hSkMOs by increasing the penetration rate of oxygen and nutrients into the core area of hSkMOs. The #hSkMOs gradually grow to more than 1.5 mm in diameter by day 60, appearing round-shaped, uniformly sized, and having relatively homogenous morphology. PAX3 and PAX7 are #myogenic progenitor markers, and their expression is verified by qRT-PCR and #cryo sections. The #myogenic cells appear as clusters, and approximately 9% of PAX7+ cells are double-positive for Ki67 at day 30, demonstrating that proliferating cells are #myogenic #progenitor s in hSkMOs. This indicates that the in vitro #hSkMO #culturesystem is able to recapitulate the features of embryonic skeletal #muscle development.
The different types of #SkeletalMuscle stem/progenitor cells that are involved in myogenesis, the process of muscle formation.
The researchers used qRT-PCR analysis and #immunohistochemistry to identify and characterize the different types of cells. They found that PAX3 and PAX7 (SC markers) were the major population during the early stage of #myogenesis, and that MYOD (proliferating and activated SC marker) and MYOG (differentiated myocyte marker) increased over time. They also observed that MYOD−/PAX7+, MYOD+/PAX7+, and MYOD+/Ki67+ cells accounted for 29%, 6%, and 8% of the putative quiescent, activated, and proliferating #SC s, respectively. MYOD+/PAX7− cells constituted 39% of differentiating myoblasts, and MYOG−/PAX7+ cells constituted 23% of putative quiescent SCs. MYOG+/PAX7− cells accounted for 30% of differentiated #myocyte s, and 8% and 6% of the MYOG+ cells in #hSkMO s co-expressed PAX7 and Ki67, respectively. This data shows that the researchers were able to identify and characterize different types of skeletal muscle stem/progenitor cells during #myogenesis.
The text is discussing the results of a research study that used hSkMOs (human skeletal muscle #organoid s) to study the development of skeletal muscle #tissue. The study found that the #hSkMO s grew exponentially in size within two months, and the growth rate then steadily decreased. The researchers then used scanning electron microscopy (SEM) imaging and confocal microscopy to examine the cytoarchitecture of the hSkMOs. They found that the hSkMOs contained a large population of terminally differentiated #myogenic cells and a small population of preserved myogenic stem/progenitor cells. They also found that the hSkMOs contained a substantial proportion of TITIN+ muscle cells and MAP2-positive #neuron s. To further characterize the presence of sustainable stem cells within the mature hSkMOs, they quantified the amount of dormant stem cells by #confocal #microscopy imaging. The results showed that approximately 56%, 31%, and 5% of PAX7+/Ki67- putative dormant stem cells existed throughout the differentiation of hSkMOs at days 30, 70, and 130, respectively. This indicates that the hSkMOs contained mature skeletal muscle properties and had the potential for #regeneration .
The researchers wanted to see if the #hSkMO s (human #skeletal muscle #organoid s) had the ability to regenerate #muscle #tissue after damage. To test this, they treated the hSkMOs with a cardiotoxin (CTX) which is known to induce muscle inflammation and damage. They then observed a decrease in PAX7+ and MYOD+ cells in the hSkMOs. To further test the #regenerative potential of the #hSkMO s, they added interleukin-4 (IL-4) to the medium to promote #muscleregeneration. After 14 days, they observed a significant increase in MYOG+ myocytes in the CTX-injured hSkMOs with the treatment of IL-4 compared to the CTX-injured hSkMOs without the treatment. This suggests that the hSkMOs have the potential to regenerate muscle tissue after damage.
Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration
Authors :
Min-Kyoung Shin , Jin Seok Bang , Jeoung Eun Lee , Hoang-Dai Tran , Genehong Park , Dong Ryul Lee and Junghyun Jo
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Very cool: Animals are key to restoring the world's forests, long-term data set reveals
Our tendency to be literal, concrete and thing-focused is boundless. In response the world keeps trying to show us, it’s *relations* all the way down.
#ecology #restoration #forests #regeneration #relationality
https://phys.org/news/2022-11-animals-key-world-forests-long-term.html
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Because the search function here doesn't work so well, as I've seen others do, here is a list of hashtags # I'm following (some of which I'm also adding to my profile):
#DevBio
#DevBiol
#Development
#Myoverse (as a possible equivalent of #Myotwitter )
#Morphogenesis
#Regeneration #MuscularDystrophy
#FSHD
#Mechanobiology
#CellBiology
#Neurobiology
#NeuroDev
#Imaging
#biorxiv
#preLights
#Microscopy
#axonguidance
