#regeneration — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #regeneration, aggregated by home.social.
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Düsseldorf Marathon: So regenerieren Sie nachher richtig
42,195 Kilometer laufen – das ist wahrlich eine große Menge. Darauf muss nicht nur über lange Zeit hintrainiert…
#Duesseldorf #Deutschland #Deutsch #DE #Schlagzeilen #Headlines #Nachrichten #News #Europe #Europa #EU #Düsseldorf #entscheidend #Gajus #Germany #immunsystem #Körper #Marathon #Mobilitätstraining #Muskeln #Nordrhein-Westfalen #regeneration #regenerieren #Sehnen #Training #Trainingszustand
https://www.europesays.com/de/975907/ -
affordabletravelbookstorereadact.blogspot.com/2025/10/now-... #Accountability #civicempowerment #ClimateJustice #Earthhealing #ethicalleadership #ethicalreform #ethicsinaction #globalregeneration #moralrenewal #regeneration #sustainability #transparency #TheBeatles #LiverpoolUK
Now and Then — Where Accountab... -
[Lucidité et coopération - nos formations 2026]
📣 Pour une démocratie lucide et coopérative, il nous semble essentiel de déployer des moyens conséquents pour
🌿 🌿Faire ensemble autrement ! 🌿 🌿Voici nos propositions pour le premier semestre 2026
https://universite-du-nous.org/blog/nos-actus-5/lucidite-et-cooperation-69#scrollTop=0#gouvernance #management #entrepriseagile #agile #cultureentreprise #innovationRH #ressourceshumaines #gouvernancepartagee #webformation #eformation #elearning #selfmanagement #transitionRH #regeneration
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Can animals like zebrafish teach us how to regrow the human spine? The science says maybe. Discover how researchers are getting closer than ever. #regeneration #spinalcord #neuroscience
https://geekoo.news/how-zebrafish-and-neonatal-mice-inspire-spinal-cord-regeneration/
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Can animals like zebrafish teach us how to regrow the human spine? The science says maybe. Discover how researchers are getting closer than ever. #regeneration #spinalcord #neuroscience
https://geekoo.news/how-zebrafish-and-neonatal-mice-inspire-spinal-cord-regeneration/
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Can animals like zebrafish teach us how to regrow the human spine? The science says maybe. Discover how researchers are getting closer than ever. #regeneration #spinalcord #neuroscience
https://geekoo.news/how-zebrafish-and-neonatal-mice-inspire-spinal-cord-regeneration/
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Can animals like zebrafish teach us how to regrow the human spine? The science says maybe. Discover how researchers are getting closer than ever. #regeneration #spinalcord #neuroscience
https://geekoo.news/how-zebrafish-and-neonatal-mice-inspire-spinal-cord-regeneration/
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If you're interested in learning how you can more deeply participate in or support our mission of building community sovereignty and stewarding abused land, you can find options for in-person or financial participation on our website:
https://rancholibertad.com/participate
We just opened our Supporter tier, and look forward to offering more opportunities to support locally and from afar in August. Those who subscribe at the Supporter tier receive a twice yearly gift basket of goodies from the Ranch (the first will be sent in December) as well as access to participate in quarterly Q&A posts.
You will also know (perhaps most importantly) that you are tangibly supporting projects that enable us to better serve residents (now and in the future), guests seeking sanctuary, and the land. Projects such as tree planting, renewable energy infrastructure, sustainable building, animal stewardship, sustainable and place-sensible food production, and more.
We are so grateful to you for your interest and collaboration ✨
#MutualAid #ClimateDirectAction #ClimateChange #Renewable #Regeneration #RegenerativeAg #Permaculture #RanchoDeLaLibertad #Community #CommunitySovereignty #IndigenousOwned #WomanOwned
-
If you're interested in learning how you can more deeply participate in or support our mission of building community sovereignty and stewarding abused land, you can find options for in-person or financial participation on our website:
https://rancholibertad.com/participate
We just opened our Supporter tier, and look forward to offering more opportunities to support locally and from afar in August. Those who subscribe at the Supporter tier receive a twice yearly gift basket of goodies from the Ranch (the first will be sent in December) as well as access to participate in quarterly Q&A posts.
You will also know (perhaps most importantly) that you are tangibly supporting projects that enable us to better serve residents (now and in the future), guests seeking sanctuary, and the land. Projects such as tree planting, renewable energy infrastructure, sustainable building, animal stewardship, sustainable and place-sensible food production, and more.
We are so grateful to you for your interest and collaboration ✨
#MutualAid #ClimateDirectAction #ClimateChange #Renewable #Regeneration #RegenerativeAg #Permaculture #RanchoDeLaLibertad #Community #CommunitySovereignty #IndigenousOwned #WomanOwned
-
If you're interested in learning how you can more deeply participate in or support our mission of building community sovereignty and stewarding abused land, you can find options for in-person or financial participation on our website:
https://rancholibertad.com/participate
We just opened our Supporter tier, and look forward to offering more opportunities to support locally and from afar in August. Those who subscribe at the Supporter tier receive a twice yearly gift basket of goodies from the Ranch (the first will be sent in December) as well as access to participate in quarterly Q&A posts.
You will also know (perhaps most importantly) that you are tangibly supporting projects that enable us to better serve residents (now and in the future), guests seeking sanctuary, and the land. Projects such as tree planting, renewable energy infrastructure, sustainable building, animal stewardship, sustainable and place-sensible food production, and more.
We are so grateful to you for your interest and collaboration ✨
#MutualAid #ClimateDirectAction #ClimateChange #Renewable #Regeneration #RegenerativeAg #Permaculture #RanchoDeLaLibertad #Community #CommunitySovereignty #IndigenousOwned #WomanOwned
-
If you're interested in learning how you can more deeply participate in or support our mission of building community sovereignty and stewarding abused land, you can find options for in-person or financial participation on our website:
https://rancholibertad.com/participate
We just opened our Supporter tier, and look forward to offering more opportunities to support locally and from afar in August. Those who subscribe at the Supporter tier receive a twice yearly gift basket of goodies from the Ranch (the first will be sent in December) as well as access to participate in quarterly Q&A posts.
You will also know (perhaps most importantly) that you are tangibly supporting projects that enable us to better serve residents (now and in the future), guests seeking sanctuary, and the land. Projects such as tree planting, renewable energy infrastructure, sustainable building, animal stewardship, sustainable and place-sensible food production, and more.
We are so grateful to you for your interest and collaboration ✨
#MutualAid #ClimateDirectAction #ClimateChange #Renewable #Regeneration #RegenerativeAg #Permaculture #RanchoDeLaLibertad #Community #CommunitySovereignty #IndigenousOwned #WomanOwned
-
If you're interested in learning how you can more deeply participate in or support our mission of building community sovereignty and stewarding abused land, you can find options for in-person or financial participation on our website:
https://rancholibertad.com/participate
We just opened our Supporter tier, and look forward to offering more opportunities to support locally and from afar in August. Those who subscribe at the Supporter tier receive a twice yearly gift basket of goodies from the Ranch (the first will be sent in December) as well as access to participate in quarterly Q&A posts.
You will also know (perhaps most importantly) that you are tangibly supporting projects that enable us to better serve residents (now and in the future), guests seeking sanctuary, and the land. Projects such as tree planting, renewable energy infrastructure, sustainable building, animal stewardship, sustainable and place-sensible food production, and more.
We are so grateful to you for your interest and collaboration ✨
#MutualAid #ClimateDirectAction #ClimateChange #Renewable #Regeneration #RegenerativeAg #Permaculture #RanchoDeLaLibertad #Community #CommunitySovereignty #IndigenousOwned #WomanOwned
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Upon the event of my pathetically over-booked #apotheosis I #need to be addressed as #Dahl #E #Pardon.
It will streamline the new character sheet #regeneration #process considerably.
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Australia’s carbon credits system a failure on global scale, study finds
"Researchers find carbon offsets approach, which is supposed to regenerate scrubby outback forests, was not reducing emissions as promised."
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https://www.theguardian.com/environment/2024/mar/27/australias-carbon-credits-system-a-failure-on-global-scale-study-findsAustralian human-induced native forest regeneration carbon offset projects have limited impact on changes in woody vegetation cover and carbon removals (study)
"Effective offset schemes require constant scrutiny and critical assessment, including from third parties. This cannot be provided without the public release of all information that is necessary for the proper evaluation of the performance and integrity of offset projects."
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https://www.nature.com/articles/s43247-024-01313-x
#ClimateCrisis #FossilFuels #offsets #transparency #integrity #regeneration #Australia #ParisAgreement #InternationalMitigation #obligation #CarbonOffset #NativeForests #LandManagement #HumanInducedRegeneration #HIR #pollution -
Australia’s carbon credits system a failure on global scale, study finds
"Researchers find carbon offsets approach, which is supposed to regenerate scrubby outback forests, was not reducing emissions as promised."
>>
https://www.theguardian.com/environment/2024/mar/27/australias-carbon-credits-system-a-failure-on-global-scale-study-findsAustralian human-induced native forest regeneration carbon offset projects have limited impact on changes in woody vegetation cover and carbon removals (study)
"Effective offset schemes require constant scrutiny and critical assessment, including from third parties. This cannot be provided without the public release of all information that is necessary for the proper evaluation of the performance and integrity of offset projects."
>>
https://www.nature.com/articles/s43247-024-01313-x
#ClimateCrisis #FossilFuels #offsets #transparency #integrity #regeneration #Australia #ParisAgreement #InternationalMitigation #obligation #CarbonOffset #NativeForests #LandManagement #HumanInducedRegeneration #HIR #pollution -
"Il faut que les femmes fassent des fils à envoyer aux usines ou à la mort. L’État moderne est martial, car son pouvoir repose sur la défense armée."
En mars 2023, Olivier Brahic, directeur de l’Agence régionale de la santé, déclarait : « Je n’aime pas beaucoup ce terme, mais c’est cela : on va proposer aux jeunes mères une stérilisation. En clair, on leur proposera de leur ligaturer les trompes ».
Françoise Vergès : https://www.bondyblog.fr/opinions/interview/rearmement-demographique-nous-faisons-face-a-des-forces-profondement-reactionnaires/
#natalité #naissances #décoloniale #travail #famille #réarmement #national #hommage #guerre #consentement #macronisme #macronie #Macron #Lepénisation #pétainisme #jeunesse #Attal #regénération #autorité #autoritarisme #uniforme #nostalgie #natalisme #déclin #uniforme #militarisation #adaptation #SNU #sacrifice #lepenisation #réaction #réactionnaire #Mayotte
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"Il faut que les femmes fassent des fils à envoyer aux usines ou à la mort. L’État moderne est martial, car son pouvoir repose sur la défense armée."
En mars 2023, Olivier Brahic, directeur de l’Agence régionale de la santé, déclarait : « Je n’aime pas beaucoup ce terme, mais c’est cela : on va proposer aux jeunes mères une stérilisation. En clair, on leur proposera de leur ligaturer les trompes ».
Françoise Vergès : https://www.bondyblog.fr/opinions/interview/rearmement-demographique-nous-faisons-face-a-des-forces-profondement-reactionnaires/
#natalité #naissances #décoloniale #travail #famille #réarmement #national #hommage #guerre #consentement #macronisme #macronie #Macron #Lepénisation #pétainisme #jeunesse #Attal #regénération #autorité #autoritarisme #uniforme #nostalgie #natalisme #déclin #uniforme #militarisation #adaptation #SNU #sacrifice #lepenisation #réaction #réactionnaire #Mayotte
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« survivalisme d’État »
L’uniforme et le SNU sont autant de moyens de nous discipliner et de nous apprendre le sens du devoir.
« Nous sommes dans un culte de l’adaptation[, …] une technologie de consentement au désastre. »Thierry Ribault : https://reporterre.net/Macron-prepare-la-militarisation-de-la-societe
#travail #famille #réarmement #national #hommage #guerre #consentement #macronisme #macronie #Macron #Lepénisation #pétainisme #jeunesse #Attal #AmélieOudéaCastéra #OudéaCastéra #AOC #regénération #autorité #autoritarisme #uniforme #nostalgie #natalisme #déclin #uniforme #militarisation #adaptation #SNU #sacrifice
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A healing #wound is a microcosm of many cell states found during #organogenesis. In addition to dead and dying cells, one may find proliferating cells, migrating cells, and cells that are differentiating or switching fate. How is this multitude of cell states, often mutually exclusive, established and maintained for successful repair and #regeneration?
--from Primer by Tin Tin Su in @PLOSBiology
#developmentalbiology
#differentiation
#cellfatehttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002155
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A healing #wound is a microcosm of many cell states found during #organogenesis. In addition to dead and dying cells, one may find proliferating cells, migrating cells, and cells that are differentiating or switching fate. How is this multitude of cell states, often mutually exclusive, established and maintained for successful repair and #regeneration?
--from Primer by Tin Tin Su in @PLOSBiology
#developmentalbiology
#differentiation
#cellfatehttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002155
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Future Money Ends All Wars https://paulio10.wordpress.com/2023/01/18/future-money-ends-all-wars/
#NewMoney #FutureMoney #Abundance #VotingMoney #MoneyVoting #NetPositiveMoney #EndWar #StopWar #NoMoreWar #Happiness #FutureSuccess #FutureOfHumanity #FutureHumanity #FutureWorld #Regeneration #SharingResources #NatureRegeneration -
CW: Using Human Pluripotent Stem Cells to Create Human Skeletal Muscle Organoids for Repair and Regeneration
Skeletal #muscle is a type of tissue that makes up a large part of the human body. It is made up of many different cells that are able to contract and move. Skeletal muscle has the ability to #repair itself when it is damaged due to #aging, exercise, or diseases like #MuscularDystrophy. A small group of cells called #SatelliteCell s help with the repair process. Scientists have been trying to create models to study how #Skeletalmuscle develops and regenerates. Recently, they have been using human pluripotent #StemCell to create 3D models of skeletal muscle tissue. However, these models have not been able to recreate the full process of muscle regeneration. In this research paper, the authors introduce a new method of using human pluripotent stem cells to create 3D models of skeletal muscle tissue that can retain the ability to repair itself.
Over the past decades, scientists have used #animalmodel to study #muscleregeneration, which is regulated by #stemcell s. These animal models have been very helpful in understanding the mechanisms of muscle #regeneration, but they don't always accurately reflect the same range of diseases that humans experience. Therefore, researchers have suggested creating reliable in vitro models using human muscle cells. ( #hPSC s) could be used to create 3D human skeletal muscle #organoid s ( #hSkMO s) that contain sustainable #stemcell and distinct myofibers with the same proteins and structure as adult muscles. Previous approaches to skeletal muscle differentiation have been developed using 2D #culture systems, but these lack the natural environment and #StemCell niche that are necessary to model adult #myogenesis and muscle #regeneration.
#Stemcell s ( #SC s) can be used to repair damaged muscle tissue. They explain that SCs can be activated in response to muscle injuries and that other #cell types can contribute to the process of #myogenesis. The author then goes on to explain that #cytokine s, such as IL-4, can influence the #InflammatorySystem and promote SCs differentiation, which helps with muscle regeneration. While #organoid s generated from #hPSC s have potential, they do not fully replicate the in vivo native microenvironment. To address this, treat the #hSkMO s with extrinsic #cytokine s to promote #muscle #regeneration . #hSkMO s might then be used to study aspects of human muscle #biology and to identify novel #therapeutic candidates for muscle-wasting disorders.
To create a 3D structure of muscle tissue. They used #WNT activator and #BMP inhibitors at the beginning of the differentiation process to induce paraxial #mesodermal #cell s. They then added #FGF2 to the Matrigel to promote the 3D structure. #HGF and IGF1 were added later to accelerate the #myogenic specification and further #myofiber differentiation. They optimized the timing of the Matrigel embedding to day seven. After this, they observed #neuralcell s and withdrew FGF2 to focus on muscle tissue development. They then prolonged the HGF and IGF1 treatment to propagate #myogenic #progenitor s. They found that 62% of the #tissue was #skeletalmuscle tissue and that it contained PAX7+ #myogenic #stem / #progenitor cells, MYOD+ activated/committed #myoblast s, and MYOG+ #myocyte s. They also found that 31% of PAX7+/Ki67− and 29% of MYOD−/PAX7+ non-dividing quiescent SCs were present in the mature #hSkMO s. This indicates that the #hSkMO s were able to effectively recreate #embryo nic #myogenesis and have regenerative potential. Future studies using #singlecell #RNA sequencing may be necessary to further characterize the different types of cells in #hSkMO s.
The stepwise process to generate human skeletal muscle organoid s (hSkMOs) from human pluripotent stem cells (hPSCs)
The process begins with dissociating #hPSC s into #singlecell s and allowing them to form #embryoid bodies ( #EB s) in low-attachment V-shaped 96-well plates. Then, paraxial #mesodermal differentiation is promoted with #WNT activation, BMP inhibition, and FGF2 signaling. The expression of pluripotency markers OCT4 and NANOG decreases, and the expression of #mesoderm markers Brachyury, T-Box transcription factor 6 (TBX6), and mesogenin 1 (MSGN1) increases. To further characterize paraxial #mesoderm al differentiation, TBX6 is #immunostain ed. After paraxial #mesodermal induction, the #organoid s are embedded with growth factor-reduced Matrigel and transferred to a six-well plate on an orbital shaker. Growth factors are then added to the #myogenic specification media, and #hSkMO s are cultured until the day of analysis. The orbital shaker improves the viability, survival, and differentiation of hSkMOs by increasing the penetration rate of oxygen and nutrients into the core area of hSkMOs. The #hSkMOs gradually grow to more than 1.5 mm in diameter by day 60, appearing round-shaped, uniformly sized, and having relatively homogenous morphology. PAX3 and PAX7 are #myogenic progenitor markers, and their expression is verified by qRT-PCR and #cryo sections. The #myogenic cells appear as clusters, and approximately 9% of PAX7+ cells are double-positive for Ki67 at day 30, demonstrating that proliferating cells are #myogenic #progenitor s in hSkMOs. This indicates that the in vitro #hSkMO #culturesystem is able to recapitulate the features of embryonic skeletal #muscle development.
The different types of #SkeletalMuscle stem/progenitor cells that are involved in myogenesis, the process of muscle formation.
The researchers used qRT-PCR analysis and #immunohistochemistry to identify and characterize the different types of cells. They found that PAX3 and PAX7 (SC markers) were the major population during the early stage of #myogenesis, and that MYOD (proliferating and activated SC marker) and MYOG (differentiated myocyte marker) increased over time. They also observed that MYOD−/PAX7+, MYOD+/PAX7+, and MYOD+/Ki67+ cells accounted for 29%, 6%, and 8% of the putative quiescent, activated, and proliferating #SC s, respectively. MYOD+/PAX7− cells constituted 39% of differentiating myoblasts, and MYOG−/PAX7+ cells constituted 23% of putative quiescent SCs. MYOG+/PAX7− cells accounted for 30% of differentiated #myocyte s, and 8% and 6% of the MYOG+ cells in #hSkMO s co-expressed PAX7 and Ki67, respectively. This data shows that the researchers were able to identify and characterize different types of skeletal muscle stem/progenitor cells during #myogenesis.
The text is discussing the results of a research study that used hSkMOs (human skeletal muscle #organoid s) to study the development of skeletal muscle #tissue. The study found that the #hSkMO s grew exponentially in size within two months, and the growth rate then steadily decreased. The researchers then used scanning electron microscopy (SEM) imaging and confocal microscopy to examine the cytoarchitecture of the hSkMOs. They found that the hSkMOs contained a large population of terminally differentiated #myogenic cells and a small population of preserved myogenic stem/progenitor cells. They also found that the hSkMOs contained a substantial proportion of TITIN+ muscle cells and MAP2-positive #neuron s. To further characterize the presence of sustainable stem cells within the mature hSkMOs, they quantified the amount of dormant stem cells by #confocal #microscopy imaging. The results showed that approximately 56%, 31%, and 5% of PAX7+/Ki67- putative dormant stem cells existed throughout the differentiation of hSkMOs at days 30, 70, and 130, respectively. This indicates that the hSkMOs contained mature skeletal muscle properties and had the potential for #regeneration .
The researchers wanted to see if the #hSkMO s (human #skeletal muscle #organoid s) had the ability to regenerate #muscle #tissue after damage. To test this, they treated the hSkMOs with a cardiotoxin (CTX) which is known to induce muscle inflammation and damage. They then observed a decrease in PAX7+ and MYOD+ cells in the hSkMOs. To further test the #regenerative potential of the #hSkMO s, they added interleukin-4 (IL-4) to the medium to promote #muscleregeneration. After 14 days, they observed a significant increase in MYOG+ myocytes in the CTX-injured hSkMOs with the treatment of IL-4 compared to the CTX-injured hSkMOs without the treatment. This suggests that the hSkMOs have the potential to regenerate muscle tissue after damage.
Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration
Authors :
Min-Kyoung Shin , Jin Seok Bang , Jeoung Eun Lee , Hoang-Dai Tran , Genehong Park , Dong Ryul Lee and Junghyun Jo
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Refurbished flats at the #ParkHill Estate, #Sheffield. Bricks and concrete. #brutalist #photography #architecture #gentrification #regeneration #housing and maybe a nod to the colour palette of #LeCorbusier #MachineForLiving -
Refurbished flats at the #ParkHill Estate, #Sheffield. Bricks and concrete. #brutalist #photography #architecture #gentrification #regeneration #housing and maybe a nod to the colour palette of #LeCorbusier #MachineForLiving
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Refurbished flats at the #ParkHill Estate, #Sheffield. Bricks and concrete. #brutalist #photography #architecture #gentrification #regeneration #housing and maybe a nod to the colour palette of #LeCorbusier #MachineForLiving -
Refurbished flats at the #ParkHill Estate, #Sheffield. Bricks and concrete. #brutalist #photography #architecture #gentrification #regeneration #housing and maybe a nod to the colour palette of #LeCorbusier #MachineForLiving
