#monoclonalantibody — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #monoclonalantibody, aggregated by home.social.
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https://www.europesays.com/ie/670927/ Microscopic peptide droplets reduce colorectal tumor growth in mice #Antibodies #Antibody #cancer #Cell #Colorectal #ColorectalCancer #Éire #Gene #IE #ImmuneSystem #immunotherapy #Ireland #Manufacturing #medicine #MonoclonalAntibody #PDL1 #Research #RNA #siRNA #Technology
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European Commission grants orphan designation for Lundbeck’s investigational anti-ACTH monoclonal antibody asedebart for Cushing’s syndrome of endogenous origin
The European Commission has gran…
#Europe #EU #ACTHlevels #adrenalgland #adrenocorticotropichormone #Cushing'sdisease #Cushing'ssyndrome #diseaseburden #endocrinedisorder #EuropeanCommission #EuropeanUnion #Lundbeck #monoclonalantibody #OrphanDesignation #pituitarytumor #treatmentoptions
https://www.europesays.com/europe/122278/ -
https://www.europesays.com/dk/?p=144897 Novo Nordisk’s ziltivekimab misses Phase 3 primary endpoint #ARTEMISTrial #ASCVD #CardiometabolicDisease #CardiovascularInflammation #CKD #CorvidiaTherapeutics #HERMESTrial #IL6Inhibitor #MACE #MonoclonalAntibody #NonCashImpairmentCharge #NovoNordisk #Phase3Trial #ZEUSTrial #ziltivekimab
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WHO launches PARTNERS clinical trial for Bundibugyo virus treatments
In a major international effort to evaluate potential treatments for Ebola disease due to Bundibugyo virus (BVD), the…
#NewsBeep #News #Health #Antibody #AU #Australia #clinicaltrial #Ebolavirusdisease #medicine #MonoclonalAntibody #pandemic #publichealth #Remdesivir #research #Therapeutics #virus
https://www.newsbeep.com/au/776560/ -
https://www.europesays.com/ie/566966/ WHO launches PARTNERS clinical trial for Bundibugyo virus treatments #Antibody #ClinicalTrial #EbolaVirusDisease #Éire #Health #IE #Ireland #medicine #MonoclonalAntibody #Pandemic #PublicHealth #Remdesivir #Research #Therapeutics #virus
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https://www.europesays.com/ie/562755/ Monoclonal antibody shows promise for treating acute respiratory distress syndrome #AcuteRespiratoryDistressSyndrome #Antibodies #Antibody #blood #cancer #ClinicalTrial #Covid19 #CriticalCare #Éire #fibrosis #Health #IE #ImmuneResponse #inflammation #Ireland #Laboratory #Lungs #medicine #MonoclonalAntibody #Mortality #Oxygen #Pandemic #Placebo #Research #Respiratory #Syndrome #ventilator
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https://www.europesays.com/ie/553520/ New drug combo may preserve muscle during weight loss #Éire #Health #IE #Ireland #LeanBodyMass #Medication #MonoclonalAntibody #MuscleMass #WeightLoss
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New drug combo may preserve muscle during weight loss
(NewsNation) — A recent trial suggests apitegromab, when used alongside tirzepatide, may help preserve lean body mass while…
#NewsBeep #News #Medication #CA #Canada #Health #leanbodymass #MonoclonalAntibody #musclemass #WeightLoss
https://www.newsbeep.com/ca/755028/ -
https://www.europesays.com/ie/538753/ Heart tissue repair drug may also help repair and regenerate damaged kidney tissues #Antibodies #Antibody #Cell #ClinicalTrial #Drugs #Éire #Health #Heart #HeartAttack #IE #ImmuneSystem #Ireland #Kidney #Laboratory #medicine #MonoclonalAntibody #Protein #Research #Scar
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https://www.europesays.com/ch/81485/ Roche pens $1B deal for respiratory bispecific from China #asthma #biobucks #biotech #BispecificAntibodies #china #COPD #Deals #FierceBiotechHomepage #LicensingDeals #MonoclonalAntibody #RespiratoryDiseases #Roche
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https://www.europesays.com/ie/527366/ Apitegromab helps tirzepatide users lose fat while preserving lean mass #Antibody #blood #ClinicalTrial #diabetes #Drugs #Efficacy #Éire #Health #IE #Ireland #Laboratory #medicine #MonoclonalAntibody #Muscle #Obesity #Placebo #Protein #WeightLoss
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https://www.europesays.com/ie/514225/ Singapore becomes first APAC market to approve MSD’s Enflonsia for infant RSV prevention #clesrovimab #Éire #ENFLONSIA #Health #HSASingapore #IE #InfantRSV #Ireland #MonoclonalAntibody #msd #Paediatrics #PreventiveCare #RespiratorySyncytialVirus #RSVPrevention
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https://www.europesays.com/britain/51372/ What’s going on with the AstraZeneca share price now? #AstraZeneca #EarningsGrowth #MonoclonalAntibody #SharePrice
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https://www.europesays.com/africa/170254/ Chromatography Systems Market in Algeria | Report – IndexBox #Algeria #BiopharmaMarketReport #ChromatographySystems #ContinuousCounterCurrentTangentialChromatography(CCTC) #forecast #GeneTherapyVectorPurification #HighThroughputScreening(HTS)CompatibleSystems #MarketAnalysis #MonoclonalAntibody(mAb)Purification #MultiColumnChromatography(MCC) #RecombinantProteinPurification #SimulatedMovingBed(SMB) #VaccinePurification
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Sterile Liquid Filters Market in Denmark | Report – IndexBox
This report is a…
#Denmark #Danmark #DK #Europe #Europa #EU #AsymmetricPES(Polyethersulfone)membranes #biopharmamarketreport #denmark #forecast #gamma-irradiatedassemblies #GeneTherapyViralVectorPurification #HollowfiberTFF #MarketAnalysis #MonoclonalAntibody(mAb)Purification #Pre-packed #RecombinantProteinFinalFill #sterileliquidfilters #VaccineDownstreamProcessing #Virus-retentiveparvovirusfilters
https://www.europesays.com/2891182/ -
https://www.europesays.com/2891182/ Sterile Liquid Filters Market in Denmark | Report – IndexBox #AsymmetricPES(Polyethersulfone)Membranes #BiopharmaMarketReport #Danmark #denmark #forecast #GammaIrradiatedAssemblies #GeneTherapyViralVectorPurification #HollowFiberTFF #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PrePacked #RecombinantProteinFinalFill #SterileLiquidFilters #VaccineDownstreamProcessing #VirusRetentiveParvovirusFilters
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https://www.europesays.com/dk/54220/ Sterile Liquid Filters Market in Denmark | Report – IndexBox #AsymmetricPES(Polyethersulfone)Membranes #BiopharmaMarketReport #Danmark #Denmark #forecast #GammaIrradiatedAssemblies #GeneTherapyViralVectorPurification #HollowFiberTFF #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PrePacked #RecombinantProteinFinalFill #SterileLiquidFilters #VaccineDownstreamProcessing #VirusRetentiveParvovirusFilters
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Sterile Liquid Filters Market in Denmark | Report – IndexBox https://www.byteseu.com/1913234/ #AsymmetricPES(Polyethersulfone)Membranes #BiopharmaMarketReport #Denmark #forecast #GammaIrradiatedAssemblies #GeneTherapyViralVectorPurification #HollowFiberTFF #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PrePacked #RecombinantProteinFinalFill #SterileLiquidFilters #VaccineDownstreamProcessing #VirusRetentiveParvovirusFilters
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https://www.europesays.com/africa/167092/ Bioreactors and Fermenters Market in South Africa | Report – IndexBox #AdvancedProcessControl(PAT #Africa #BiopharmaMarketReport #BioreactorsAndFermenters #DigitalTwins #forecast #MarineImpeller)AndAerationSystems #MarketAnalysis #ModularAndPortableSkidDesigns #MonoclonalAntibody(mAb)Production #PitchedBlade #RecombinantProteinProduction #ScalableAgitation(eG #SingleUseBag/filmTechnology #SouthAfrica #VaccineAntigenProduction #ViralVectorProduction(forCGT)
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Columns Market in Denmark | Report – IndexBox https://www.byteseu.com/1911639/ #BiopharmaMarketReport #columns #Denmark #forecast #GeneTherapyVectorPurification #HighFlowRate&HighPressureCapableDesigns #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PlasmaFractionation #Sanitary&SterilizableConnections(eG #ScalableColumnGeometry(diameterToHeightRatios) #SingleUse/DisposableColumnDesign #TriClamp) #VaccinePurification
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Columns Market in Denmark | Report – IndexBox
This report is an …
#Denmark #Danmark #DK #Europe #Europa #EU #biopharmamarketreport #columns #denmark #forecast #GeneTherapyVectorPurification #High-FlowRate&High-PressureCapableDesigns #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PlasmaFractionation #Sanitary&SterilizableConnections(e.g. #ScalableColumnGeometry(diameter-to-heightratios) #Single-Use/DisposableColumnDesign #Tri-Clamp) #VaccinePurification
https://www.europesays.com/2889204/ -
https://www.europesays.com/dk/53574/ Columns Market in Denmark | Report – IndexBox #BiopharmaMarketReport #Columns #Danmark #Denmark #forecast #GeneTherapyVectorPurification #HighFlowRate&HighPressureCapableDesigns #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PlasmaFractionation #Sanitary&SterilizableConnections(eG #ScalableColumnGeometry(diameterToHeightRatios) #SingleUse/DisposableColumnDesign #TriClamp) #VaccinePurification
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https://www.europesays.com/2889204/ Columns Market in Denmark | Report – IndexBox #BiopharmaMarketReport #columns #Danmark #denmark #forecast #GeneTherapyVectorPurification #HighFlowRate&HighPressureCapableDesigns #MarketAnalysis #MonoclonalAntibody(mAb)Purification #PlasmaFractionation #Sanitary&SterilizableConnections(eG #ScalableColumnGeometry(diameterToHeightRatios) #SingleUse/DisposableColumnDesign #TriClamp) #VaccinePurification
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Investigating microglia’s role in Alzheimer’s pathology
Announcing a new article publication for BIO Integration journal. Alzheimer’s disease (AD) is a neurodegenerative disorder and the…
#NewsBeep #News #Health #Agonist #Alzheimer'sdisease #Antibody #Brain #CA #Canada #Cell #CentralNervousSystem #Dementia #language #Ligand #Microglia #MonoclonalAntibody #nervoussystem #neurodegenerativedisorder #Pathology #Receptor #RNA #RNAsequencing #Transcriptomics
https://www.newsbeep.com/ca/508841/ -
https://www.europesays.com/ie/363426/ Investigating microglia’s role in Alzheimer’s pathology #Agonist #Alzheimer'sDisease #Antibody #Brain #Cell #CentralNervousSystem #dementia #Éire #Health #IE #Ireland #Language #Ligand #microglia #MonoclonalAntibody #NervousSystem #NeurodegenerativeDisorder #Pathology #Receptor #RNA #RNASequencing #Transcriptomics
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https://www.europesays.com/ie/339364/ Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation #Adenovirus #Antibodies #Antibody #blood #cancer #Cell #Covid19 #Cytokine #Efficacy #Éire #Gene #Health #IE #immunity #Ireland #LungCancer #MassSpectrometry #MonoclonalAntibody #Omicron #Receptor #Respiratory #SARS #SarsCov2 #Spectrometry #Throat #Vaccine #virus
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**VNVC bắt đầu tiêm kháng thể đơn dòng phòng RSV cho trẻ từ ngày 23/12. Dịch vụ triển khai tại 250+ trung tâm trên cả nước, giúp bảo vệ trẻ sơ sinh & nhũ nhi trước nguy cơ viêm phổi, viêm tiểu phế quản trong mùa dịch hô hấp cao điểm.**
#VNVC #SứcKhỏeTrẻEm #PhòngBệnh #RSV
#Healthcare #ChildHealth #RSVPrevention #MonoclonalAntibodyhttps://vietnamnet.vn/vnvc-trien-khai-tiem-khang-the-don-dong-phong-rsv-cho-tre-nho-2475397.html
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https://www.europesays.com/ie/230341/ Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children #Antibody #bevacizumab #cancer #chemotherapy #children #ClinicalTrial #Drugs #Éire #Health #IE #immunotherapy #Ireland #MonoclonalAntibody #Neuroblastoma #oncology #Research
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https://www.europesays.com/ie/217283/ Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer #Antibody #blood #BloodVessels #BreastCancer #cancer #Cell #CellDeath #chemotherapy #Doxorubicin #Éire #Health #Hormone #IE #ImmuneSystem #Interferon #InterferonGamma #Ireland #Lungs #Metastasis #MonoclonalAntibody #Preclinical #Protein #Research #Surgery #Therapeutics #therapy #Tumor #TumorAssociatedMacrophages
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Preparing for the respiratory virus season: A guide for families
As respiratory virus season begins, pediatric experts are preparing for an expected rise in cases of …
#NewsBeep #News #Health #Antibodies #Antibody #breathing #Bronchiolitis #CA #Canada #Children #Cold #congenitalheartdisease #COVID-19 #HealthCare #Heart #heartdisease #hospital #Influenza #MonoclonalAntibody #nursing #publichealth #Respiratory #Respiratorysyncytialvirus #respiratoryvirus #virus
https://www.newsbeep.com/ca/289065/ -
https://www.europesays.com/ie/161495/ Northwestern team develops antibody to expose hidden pancreatic cancer cells #Antibodies #Antibody #cancer #chemotherapy #Éire #HIV #IE #ImmuneSystem #immunotherapy #InfectiousDiseases #Ireland #Macrophage #medicine #MonoclonalAntibody #PancreaticCancer #Phagocytosis #Preclinical #Protein #Research #Technology #therapy #Tumor
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Nirsevimab sharply cuts RSV hospitalizations in U.S. infants during the 2024–2025 season
Real-world data confirm that nirsevimab provides powerful protection for infants, reducing RSV hospital stays and easing the strain…
#NewsBeep #News #Health #Antibody #CA #Canada #Chronic #electronichealthrecord #healthsystems #Healthcare #hospital #immunization #MonoclonalAntibody #pH #publichealth #research #Respiratory #Respiratorysyncytialvirus #virus
https://www.newsbeep.com/ca/176652/ -
Strategic tips for early-stage animal health companies. https://www.byteseu.com/1318485/ #Antibody #Cell #COVID19 #DrugProduction #Drugs #Efficacy #Health #Laboratory #language #Manufacturing #Medicine #MonoclonalAntibody #Parvovirus #Tumor #vaccine #veterinary
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https://www.europesays.com/uk/340722/ Researchers find CFI deficiency alarmingly high in old order Amish #allergy #Antibody #Bacterial #brain #Children #diet #Eculizumab #ExomeSequencing #Gene #Genetic #GeneticDisorder #Genetics #Healthcare #Hospital #ImmuneSystem #Immunology #Inflammation #MonoclonalAntibody #PrimaryCare #Research #Science #UK #UnitedKingdom #Vascular
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Hympavzi (marstacimab): New Treatment for Hemophilia
On 11 October 2024, Hympavzi (marstacimab-hncq), a human monoclonal antibody targeting “tissue factor pathway inhibitor” received US FDA’s approval...........
#bleedingdisorder #HemophiaB #Hemophilia #HemophiliaA #Hympavzi #marstacimab #Monoclonalantibody
SCIEU Teamhttps://www.scientificeuropean.co.uk/medicine/hympavzi-marstacimab-new-treatment-for-hemophilia/
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Lecanemab for Early Alzheimer’s Disease approved in the UK but refused in EU
Monoclonal antibodies (mAbs) lecanemab and donanemab have been approved forthe treatment of early Alzheimer’s disease in the UK and USA respectively...........
#Alzheimer’sDisease #Dementia #EarlyAlzheimer’sDisease #EU #Lecanemab #Monoclonalantibody #onanemab #UK #usa
Umesh Prasad -
https://www.abc.net.au/news/2024-03-25/qld-rsv-jab-explainer-who-is-eligible/103630628?utm_source=abc_news_app&utm_medium=content_shared&utm_campaign=abc_news_app&utm_content=other “The state government has announced a $31 million program to immunise more than 70,000 newborn babies, eligible infants and young children.
They will be given a #MonoclonalAntibody – or man-made protein – called Nirsevimab, which is marketed as Beyfortus.
Delivered as an injection, #Nirsevimab has been shown to be about 80 per cent effective at preventing young infants from being hospitalised with lower respiratory tract infection, caused by #RSV.”
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A biotechnology company is receiving NIH support for discovering antibodies that address the vast majority of proteins coded by the human genome, passed-up so far by drug makers.
https://sciencebusiness.technewslit.com/?p=45299
#News #Press #Science #Business #Biotechnology #Chemistry #Engineering #Proteins #Antibody #Antigens #MonoclonalAntibody #GeneticEngineering #NIH #Grant #SBIR
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'Coinciding with rising awareness about the risks of R.S.V., there are finally tools available to prevent severe infections in both infants and older adults.'
#Infection #immunology #vaccines #MonoclonalAntibody #RSV -
AstraZeneca teams up with startup Quell in type 1 diabetes, IBD cell therapy pact— Activist shareholders blast Merck's IRA lawsuit --FDA advisers recommend approval of monoclonal antibody to protect newborns and young children from RSV -- See more on our front page news http://bit.ly/w28kSd #astrazeneca #type1diabetes #celltherapy #ibd #merck #shareholders #inflationreductionact #fda #rsv #monoclonalantibody #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
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Less is more for monoclonal antibody affinity?
(Particularly if deletion is not the goal)"This approach delivered higher immune cell activation, in vivo T cell expansion and antitumour activity in the case of CD40. Moreover, an inert anti-4-1BB monoclonal antibody was transformed into an agonist. Low-affinity variants of the clinically important antagonistic anti-PD-1 monoclonal antibody nivolumab also mediated more potent signalling and affected T cell activation."
#Monoclonal #MonoclonalAntibody #immunology #drugdiscovery #drugdevelopment
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My latest Clinical Pipeline column for #NatureMedicine is out, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody -
My latest Clinical Pipeline column for #NatureMedicine is out today, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody
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"The strong dependence on T cells in MS animal models (experimental autoimmune encephalomyelitis, EAE) and the absence of antibodies in MS have long driven the assumption of MS being orchestrated by T helper cells (12), making those the most plausible therapeutic targets. But anti-CD20 therapies have been a game changer in the MS field."
#Immunology #MultipleSclerosis #MonoclonalAntibody #Autoimmunity
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You'll never guess what happened next...
"The key patent on the best-selling anti-inflammatory medication, used to treat conditions like arthritis, was expiring at the end of the year. Regulators had blessed a rival version of the drug, and more copycats were close behind. The onset of competition seemed likely to push down the medication’s $50,000-a-year list price."
#TNF #RheumatoidArthritis #lupus #PublicHealth #Humira #MonoclonalAntibody
https://www.nytimes.com/2023/01/28/business/humira-abbvie-monopoly.html
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My latest clinical pipeline column for @NatureMedicine is out today.
It's a look at the recent approval of mosunetuzumab, #Genentech's bispecific anti CD20/CD3 monoclonal antibody
for relapsed or refractory follicular #lymphoma.#FollicularLymphoma #Hematology #MonoclonalAntibody #DrugDevelopment
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"Using novel humanized IBC mouse models, we discovered that EGFR-targeted therapy remodels the IBC TME by increasing cytotoxic T cells and reducing immunosuppressive regulatory T cells and M2 macrophages. These changes were due to diminishing immunosuppressive chemokine expression regulated by transcription factor EGR1. We also showed that induction of an immunoactive IBC TME by an anti-EGFR antibody improved the antitumor efficacy of an anti–PD-L1 antibody."
#Immunology #Immunotherapy #EGFR #DrugDevelopment #MonoclonalAntibody
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"The 18-month investigation, initiated by two congressional committees after the F.D.A. approved the drug, also strongly criticized Biogen, Aduhelm’s manufacturer. Internal documents showed the company set “an unjustifiably high price” of $56,000 a year for Aduhelm because it wanted a history-making “blockbuster” to “establish Aduhelm as one of the top pharmaceutical launches of all time,” even though it knew the high price would burden Medicare and patients, the report found."
#Aduhelm #MonoclonalAntibody #Alzheimer #AlzheimersDisease #Aducanumab
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Here's the fulcrum of this story, the paper where the Bluestone group and collaborators turn the mouse anti-human CD3 monoclonal into a chimeric, non-Fc activating molecule: Alegre et al, 1994
#MonoclonalAntibody #MolecularBiology #AntibodyEnginering #DrugDiscovery #DrugDevelopment #NatureMedicine #Diabetes #Type1Diabetes #Immunotherapy
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My latest clinical pipeline column for Nature Medicine is a look at a drug recently approved by the #FDA to delay the onset of type 1 diabetes.
It's a direct descendant of the very first monoclonal ever approved for clinical use.
#Diabetes #Type1Diabetes #DrugDevelopment #DrugDiscovery #NatureMedicine #Immunology #MonoclonalAntibody
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'We use data on changes in the in vivo concentration of monoclonal antibodies, and the associated protection from COVID-19, over time to model the dose-response relationship of monoclonal antibodies for prophylaxis. We estimate that 50% protection from COVID-19 is achieved with a monoclonal antibody concentration of 939-fold of the in vitro IC50 (95% CI: 135 - 2073).'
#Preprint #MonoclonalAntibody #Covid#Covid19
https://www.medrxiv.org/content/10.1101/2022.11.22.22282199v1
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Not good news on the clinically available monoclonals vs newer covid lineages.
"Our data reveal that emerging omicron sublineages are resistant to most (ie, BA.4.6, BA.2.75.2, and BJ.1) or all (BQ.1.1) clinically used mAbs. As a consequence, in patients at high risk, treatment with mAbs alone might not provide a therapeutic benefit in regions of the globe in which BQ.1.1 is spreading, suggesting that additional treatment options (eg, paxlovid or molnupiravir) should be considered. Furthermore, novel, broadly active mAbs are urgently needed for prophylactic or therapeutic treatment, or both, in patients at high risk."
#COVID #Antibody #MonoclonalAntibody
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00733-2/fulltext
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Monoclonal targeting Plasmodium falciparum circumsporozoite protein (PfCSP)
"We conducted a phase 2 trial to assess the safety and efficacy of a single intravenous infusion of CIS43LS against P. falciparum infection in healthy adults in Mali over a 6-month malaria season"
#Plasmodium #Malaria #MonoclonalAntibody #clinicaltrial
https://www.nejm.org/doi/full/10.1056/NEJMoa2206966?query=featured_home
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Treatment Triggers Teeth to Thrive - We humans like to think we’re pretty advanced, but we can’t regrow missing teeth i... - https://hackaday.com/2021/04/13/treatment-triggers-teeth-to-thrive/ #monoclonalantibodytreatment #bonemorphogenicprotein #monoclonalantibody #toothregeneration #medicalhacks #usag-1 #teeth #news