#egfr — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #egfr, aggregated by home.social.
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New smart drugs precisely target and kill cancer cells
Cancer treatment has long been haunted by the same problem: how do you strike dangerous cells without hitting…
#NewsBeep #News #Health #antibodydrugconjugates #CA #Canada #cancer #DNA #DNAhairpins #EGFR #healthnews #hybridizationchainreaction #MedicalGoodNews #Oncology #PD-L1 #PrecisionOncology #PTK7 #research #Science #smartDNAdrugdelivery #targetedcancertherapy #UniversityofGeneva
https://www.newsbeep.com/ca/580181/ -
https://www.europesays.com/es/462834/ Resultados positivos con dacomitinib en el cáncer de pulmón no microcítico #beneficio #cáncer #cerebrales #clínica #dacomitinib #egfr #ES #España #Estudio #frecuentes #habitual #Health #Metástasis #microcítico #Mutaciones #no #Pacientes #positivos #práctica #pulmón #realizado #reporta #resultados #Salud #Spain
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https://www.europesays.com/ie/236654/ Difference in kidney function tests predicts health risks #CardiovascularDisease #ChronicKidneyDisease #ChronicKidneyDiseasePrognosisConsortium #CKDPC #Creatinine #CystatinC #EGFR #Éire #EstimatedGlomerularFiltrationRate #Health #HeartFailure #IE #Ireland #JAMA #JosefCoresh #JournalOfTheAmericanMedicalAssociation #KidneyFailure #MorganGrams
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Difference in kidney function tests predicts health risks
December 16, 2025 At a Glance People with chronic kidney disease faced a higher risk of death and…
#NewsBeep #News #Health #CA #Canada #cardiovasculardisease #ChronicKidneyDisease #ChronicKidneyDiseasePrognosisConsortium #CKD-PC #creatinine #cystatin-C #EGFR #estimatedglomerularfiltrationrate #Heartfailure #JAMA #JosefCoresh #JournaloftheAmericanMedicalAssociation #KidneyFailure #MorganGrams
https://www.newsbeep.com/ca/349986/ -
https://www.europesays.com/ie/197022/ Chronic kidney disease screening in primary care: a descriptive analysis of the Girona Sud health region | BMC Primary Care #Albuminuria #ChronicKidneyDisease #EGFR #Éire #GeneralPractice/FamilyMedicine #Health #hypertension #IE #Ireland #KidneyProtectiveTherapy #PrimaryCare #PrimaryCareMedicine #RealWorldData #Screening #Type2Diabetes
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The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review | BMC Nephrology https://www.diningandcooking.com/2156231/the-impact-of-a-vegetarian-diet-on-chronic-kidney-disease-ckd-progression-a-systematic-review-bmc-nephrology/ #ChronicKidneyDisease #eGFR #InternalMedicine #Mediterranean #MediterraneanVeganDiet #MediterraneanVegetarianRecipes #nephrology #VeganMediterraneanDiet #VegetarianDiet #VegetarianMediterraneanRecipes #vegetarianism
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The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review | BMC Nephrology https://www.diningandcooking.com/2156231/the-impact-of-a-vegetarian-diet-on-chronic-kidney-disease-ckd-progression-a-systematic-review-bmc-nephrology/ #ChronicKidneyDisease #eGFR #InternalMedicine #Mediterranean #MediterraneanVeganDiet #MediterraneanVegetarianRecipes #nephrology #VeganMediterraneanDiet #VegetarianDiet #VegetarianMediterraneanRecipes #vegetarianism
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The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review | BMC Nephrology https://www.diningandcooking.com/2156231/the-impact-of-a-vegetarian-diet-on-chronic-kidney-disease-ckd-progression-a-systematic-review-bmc-nephrology/ #ChronicKidneyDisease #eGFR #InternalMedicine #Mediterranean #MediterraneanVeganDiet #MediterraneanVegetarianRecipes #nephrology #VeganMediterraneanDiet #VegetarianDiet #VegetarianMediterraneanRecipes #vegetarianism
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The Texas State Plan for #CKD #Chronic #Kidney #Disease Treatment, is 🔥 💪 www.hhs.texas.gov/sites/defaul... Key points: 1) Expands early screening 2) Acknowledges socioeconomic factors in CKD 3) Integrates #proteinuria #EGFR & #genetics 4) School screening for proteinuria & #hypertension
hhs.texas.gov/sites/default/... -
The Texas State Plan for #CKD #Chronic #Kidney #Disease Treatment, is 🔥 💪
https://www.hhs.texas.gov/sites/default/files/documents/state-plan-ckd-treatment-jan-2025.pdf
Key points:
1) Expands early screening
2) Acknowledges socioeconomic factors in CKD
3) Integrates #proteinuria #EGFR & #genetics
4) School screening for proteinuria & #hypertension -
#Phoenix_Fluor#555: Ultra-photostable fluorescent molecule reveals hidden dynamics of #intracellular #proteins.
https://phys.org/news/2025-02-phoenix-fluor-ultra-photostable-fluorescent.html
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A stealth #fungus has decimated North American #bats, but scientists may be a step closer to treating #white_nose syndrome.
#epizootic #Pseudogymnoascus #infection #keratinocytes #EGFR
https://phys.org/news/2024-07-stealth-fungus-decimated-north-american.html
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A stealth #fungus has decimated North American #bats, but scientists may be a step closer to treating #white_nose syndrome.
#epizootic #Pseudogymnoascus #infection #keratinocytes #EGFR
https://phys.org/news/2024-07-stealth-fungus-decimated-north-american.html
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A stealth #fungus has decimated North American #bats, but scientists may be a step closer to treating #white_nose syndrome.
#epizootic #Pseudogymnoascus #infection #keratinocytes #EGFR
https://phys.org/news/2024-07-stealth-fungus-decimated-north-american.html
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A stealth #fungus has decimated North American #bats, but scientists may be a step closer to treating #white_nose syndrome.
#epizootic #Pseudogymnoascus #infection #keratinocytes #EGFR
https://phys.org/news/2024-07-stealth-fungus-decimated-north-american.html
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A stealth #fungus has decimated North American #bats, but scientists may be a step closer to treating #white_nose syndrome.
#epizootic #Pseudogymnoascus #infection #keratinocytes #EGFR
https://phys.org/news/2024-07-stealth-fungus-decimated-north-american.html
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A recently developed ⭐️#cancer #vaccine for dogs⭐️ is showing promising results in clinical trials, which have been running since 2016, and there's hope that some of the benefits of the vaccine could be translated into human cancer treatments.
More than 300 dogs have been treated with the vaccine to date, and the twelve--month survival rate for canines with certain cancers has been lifted from about 35 percent to 60 percent. Tumors in many of the animals have also shrunk.
Known officially as the #Canine #EGFR/#HER2 #Peptide #Cancer #Immunotherapeutic, the treatment grew out of studies of autoimmune diseases, where the immune system damages the body's own tissue rather than any invading threats.
The vaccine is designed to get the immune system to attack cancer instead.In many ways tumors are like the targets of autoimmune diseases," says rheumatologist #Mark #Mamula, from the Yale University School of Medicine.
"Cancer cells are your own tissue and are attacked by the immune system. The difference is we want the immune system to attack a tumor."
As outlined in a 2021 study by Mamula and colleagues, the treatment gets the immune cells to produce antibody defenses, which attach themselves to tumors and interfere with their growth patterns.
Specifically, these antibodies hunt down two proteins: 🔸epidermal growth factor receptor 🔸( #EGFR ) and 🔸human epidermal growth factor receptor 2🔸 ( #HER2 ).
Mutations causing overexpression of these proteins drive uncontrolled cell division in some human and canine cancers.
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A recently developed ⭐️#cancer #vaccine for dogs⭐️ is showing promising results in clinical trials, which have been running since 2016, and there's hope that some of the benefits of the vaccine could be translated into human cancer treatments.
More than 300 dogs have been treated with the vaccine to date, and the twelve--month survival rate for canines with certain cancers has been lifted from about 35 percent to 60 percent. Tumors in many of the animals have also shrunk.
Known officially as the #Canine #EGFR/#HER2 #Peptide #Cancer #Immunotherapeutic, the treatment grew out of studies of autoimmune diseases, where the immune system damages the body's own tissue rather than any invading threats.
The vaccine is designed to get the immune system to attack cancer instead.In many ways tumors are like the targets of autoimmune diseases," says rheumatologist #Mark #Mamula, from the Yale University School of Medicine.
"Cancer cells are your own tissue and are attacked by the immune system. The difference is we want the immune system to attack a tumor."
As outlined in a 2021 study by Mamula and colleagues, the treatment gets the immune cells to produce antibody defenses, which attach themselves to tumors and interfere with their growth patterns.
Specifically, these antibodies hunt down two proteins: 🔸epidermal growth factor receptor 🔸( #EGFR ) and 🔸human epidermal growth factor receptor 2🔸 ( #HER2 ).
Mutations causing overexpression of these proteins drive uncontrolled cell division in some human and canine cancers.
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A recently developed ⭐️#cancer #vaccine for dogs⭐️ is showing promising results in clinical trials, which have been running since 2016, and there's hope that some of the benefits of the vaccine could be translated into human cancer treatments.
More than 300 dogs have been treated with the vaccine to date, and the twelve--month survival rate for canines with certain cancers has been lifted from about 35 percent to 60 percent. Tumors in many of the animals have also shrunk.
Known officially as the #Canine #EGFR/#HER2 #Peptide #Cancer #Immunotherapeutic, the treatment grew out of studies of autoimmune diseases, where the immune system damages the body's own tissue rather than any invading threats.
The vaccine is designed to get the immune system to attack cancer instead.In many ways tumors are like the targets of autoimmune diseases," says rheumatologist #Mark #Mamula, from the Yale University School of Medicine.
"Cancer cells are your own tissue and are attacked by the immune system. The difference is we want the immune system to attack a tumor."
As outlined in a 2021 study by Mamula and colleagues, the treatment gets the immune cells to produce antibody defenses, which attach themselves to tumors and interfere with their growth patterns.
Specifically, these antibodies hunt down two proteins: 🔸epidermal growth factor receptor 🔸( #EGFR ) and 🔸human epidermal growth factor receptor 2🔸 ( #HER2 ).
Mutations causing overexpression of these proteins drive uncontrolled cell division in some human and canine cancers.
-
A recently developed ⭐️#cancer #vaccine for dogs⭐️ is showing promising results in clinical trials, which have been running since 2016, and there's hope that some of the benefits of the vaccine could be translated into human cancer treatments.
More than 300 dogs have been treated with the vaccine to date, and the twelve--month survival rate for canines with certain cancers has been lifted from about 35 percent to 60 percent. Tumors in many of the animals have also shrunk.
Known officially as the #Canine #EGFR/#HER2 #Peptide #Cancer #Immunotherapeutic, the treatment grew out of studies of autoimmune diseases, where the immune system damages the body's own tissue rather than any invading threats.
The vaccine is designed to get the immune system to attack cancer instead.In many ways tumors are like the targets of autoimmune diseases," says rheumatologist #Mark #Mamula, from the Yale University School of Medicine.
"Cancer cells are your own tissue and are attacked by the immune system. The difference is we want the immune system to attack a tumor."
As outlined in a 2021 study by Mamula and colleagues, the treatment gets the immune cells to produce antibody defenses, which attach themselves to tumors and interfere with their growth patterns.
Specifically, these antibodies hunt down two proteins: 🔸epidermal growth factor receptor 🔸( #EGFR ) and 🔸human epidermal growth factor receptor 2🔸 ( #HER2 ).
Mutations causing overexpression of these proteins drive uncontrolled cell division in some human and canine cancers.
-
A recently developed ⭐️#cancer #vaccine for dogs⭐️ is showing promising results in clinical trials, which have been running since 2016, and there's hope that some of the benefits of the vaccine could be translated into human cancer treatments.
More than 300 dogs have been treated with the vaccine to date, and the twelve--month survival rate for canines with certain cancers has been lifted from about 35 percent to 60 percent. Tumors in many of the animals have also shrunk.
Known officially as the #Canine #EGFR/#HER2 #Peptide #Cancer #Immunotherapeutic, the treatment grew out of studies of autoimmune diseases, where the immune system damages the body's own tissue rather than any invading threats.
The vaccine is designed to get the immune system to attack cancer instead.In many ways tumors are like the targets of autoimmune diseases," says rheumatologist #Mark #Mamula, from the Yale University School of Medicine.
"Cancer cells are your own tissue and are attacked by the immune system. The difference is we want the immune system to attack a tumor."
As outlined in a 2021 study by Mamula and colleagues, the treatment gets the immune cells to produce antibody defenses, which attach themselves to tumors and interfere with their growth patterns.
Specifically, these antibodies hunt down two proteins: 🔸epidermal growth factor receptor 🔸( #EGFR ) and 🔸human epidermal growth factor receptor 2🔸 ( #HER2 ).
Mutations causing overexpression of these proteins drive uncontrolled cell division in some human and canine cancers.
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#EGFR signaling controls directionality of #epithelial multilayer formation upon loss of cell polarity in the #Drosophila follicular epithelium
Aiguo Tian, Wu-Min Deng et al -
Next: large database study on age-related normal decline in #eGFR.
I’m sure Prof. Glassock would like this.I forgot to ask if there will be a calculator!
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New ChemRxiv preprint! “Pitfalls and considerations in determining the potency and mutant selectivity of covalent #EGFR inhibitors.” Collaboration between our group and AssayQuant Technologies, Inc. #MedicinalChemistry #oncology https://chemrxiv.org/engage/chemrxiv/article-details/64e50861dd1a73847f5020a1
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The EGFR #phosphatase RPTPγ is a #redox-regulated suppressor of promigratory signaling
Maitreyi Joshi, Philippe Bastiaens et al show that #RPTPγ is coupled to autocatalytic, ligandless #EGFR #phosphorylation by a ROS-mediated toggle-switch, enabling ultrasensitive EGFR activation at the plasma membrane
https://www.embopress.org/doi/10.15252/embj.2022111806 -
Modeling & experimental analyses of a Golgi-localized GTPase circuitry that allows cancer cells to achieve self-sufficiency in growth factor signaling ➡️ http://bit.ly/41DK7Dj
P Rangamani & P Ghosh, UCSD
#Gproteins #CellSignaling #EGFR #SystemsBiology -
Modeling & experimental analyses of a Golgi-localized GTPase circuitry that allows cancer cells to achieve self-sufficiency in growth factor signaling ➡️ http://bit.ly/41DK7Dj
P Rangamani & P Ghosh, UCSD
#Gproteins #CellSignaling #EGFR #SystemsBiology -
Modeling & experimental analyses of a Golgi-localized GTPase circuitry that allows cancer cells to achieve self-sufficiency in growth factor signaling ➡️ http://bit.ly/41DK7Dj
P Rangamani & P Ghosh, UCSD
#Gproteins #CellSignaling #EGFR #SystemsBiology -
Modeling & experimental analyses of a Golgi-localized GTPase circuitry that allows cancer cells to achieve self-sufficiency in growth factor signaling ➡️ http://bit.ly/41DK7Dj
P Rangamani & P Ghosh, UCSD
#Gproteins #CellSignaling #EGFR #SystemsBiology -
"Using novel humanized IBC mouse models, we discovered that EGFR-targeted therapy remodels the IBC TME by increasing cytotoxic T cells and reducing immunosuppressive regulatory T cells and M2 macrophages. These changes were due to diminishing immunosuppressive chemokine expression regulated by transcription factor EGR1. We also showed that induction of an immunoactive IBC TME by an anti-EGFR antibody improved the antitumor efficacy of an anti–PD-L1 antibody."
#Immunology #Immunotherapy #EGFR #DrugDevelopment #MonoclonalAntibody