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#plasmodium — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #plasmodium, aggregated by home.social.

  1. #malaria: genome sequencing of drug resistant #plasmodium strains reveals new conserved drug targets less likely to develop resistance mutations. nature.com/articles/d41586-018

  2. Postdoctoral Researcher - P. falciparum cell cycle regulation

    LPHI, CNRS - University of Montpellier, France

    We are seeking a #postdoc to join a ERC-funded project at LPHI (Montpellier, France) to study cell cycle regulation of the #Plasmodium falciparum.

    See the full job description on jobRxiv: jobrxiv.org/job/lphi-cnrs-univ...
    jobrxiv.org/job/lphi-cnrs-univ

  3. Postdoctoral Researcher - P. falciparum cell cycle regulation

    LPHI, CNRS - University of Montpellier, France

    We are seeking a #postdoc to join a ERC-funded project at LPHI (Montpellier, France) to study cell cycle regulation of the #Plasmodium falciparum.

    See the full job description on jobRxiv: jobrxiv.org/job/lphi-cnrs-univ...
    jobrxiv.org/job/lphi-cnrs-univ

  4. #Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology plos.io/3XQeiqY

  5. #Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology plos.io/3XQeiqY

  6. #Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology plos.io/3XQeiqY

  7. #Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology plos.io/3XQeiqY

  8. #Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology plos.io/3XQeiqY

  9. The #malaria parasite #Plasmodium undergoes a unique #endomitosis during male gametogenesis. @Zeeshan_M @RitaTewari &co show that NEK1 kinase is vital for MTOC function & chromosome segregation, facilitating rapid endomitosis in Plasmodium #PLOSBiology plos.io/4e4MzJ3

  10. Defacement – Duality Review

    By Dear Hollow

    Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.

    Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal, Duality offers the best of what you love about Defacement and quite a deal more.

    Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.

    The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.

    For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.

    Rating: 3.5/5.0
    DR: N/A | Format Reviewed: STREAM
    Label: Avantgarde Music
    Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
    Releases Worldwide: July 26th, 2024

    #2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis

  11. Defacement – Duality Review

    By Dear Hollow

    Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.

    Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal, Duality offers the best of what you love about Defacement and quite a deal more.

    Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.

    The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.

    For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.

    Rating: 3.5/5.0
    DR: N/A | Format Reviewed: STREAM
    Label: Avantgarde Music
    Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
    Releases Worldwide: July 26th, 2024

    #2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis

  12. Defacement – Duality Review

    By Dear Hollow

    Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.

    Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal, Duality offers the best of what you love about Defacement and quite a deal more.

    Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.

    The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.

    For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.

    Rating: 3.5/5.0
    DR: N/A | Format Reviewed: STREAM
    Label: Avantgarde Music
    Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
    Releases Worldwide: July 26th, 2024

    #2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis

  13. How an anti-hero of the #ImmuneSystem protects from malaria blogs.biomedcentral.com/bugbit

    #Autoantibodies inhibit #Plasmodium falciparum growth and are associated with protection from clinical #malaria sciencedirect.com/science/arti

    "Malarial #disease and #autoimmune disease share a strange relationship. Both are best avoided, however when one is infected with the Plasmodium parasite it may be beneficial to have a propensity for autoimmunity."

  14. 'By employing a metabolic compartmentalization approach, we observed enhanced glycolysis and accumulation of the TCA-cycle derivative itaconate in splenic monocyte-derived dendritic cells from Plasmodium chabaudi (Pc)-infected mice.'
    #Malaria #Plasmodium #HostPathogen #Metabolism #immunology

    cell.com/cell-metabolism/fullt

  15. Why do the #malaria parasite's #merozoite surface proteins #MSPs have exactly 2 deeply-diverged lineages? Genomic analysis of #Plasmodium DBLMSP & DBLMSP2 reveals the evolutionary explanation to this long-standing puzzle @bricoletc @ZaminIqbal #PLOSBiology plos.io/3TC8WOl

  16. "Overall, these data demonstrate that IL-15C treatment, via its induction of IL-10 from NK cells, modulates the dysregulated inflammation during Plasmodium infection to promote Tfh differentiation & Ab generation, correlating with improved survival from reinfection."
    #Plasmodium #Malaria #InfectionImmunity #immunology

    journals.aai.org/jimmunol/arti

  17. So proud of this article about malaria that we wrote specifically for kids.

    It's the result of a great collaboration with people from three different continents, including Africa!

    The fantastic illustrations in the article (figures 1-4) were made by John Heim ([email protected]).

    kids.frontiersin.org/articles/

    #malaria #kids #Plasmodium #mosquito

  18. An “unprecedented” atlas of the subcellular organisation of proliferative blood-stage #malaria parasites using expansion microscopy. #Plasmodium #Microbiology elifesciences.org/articles/880

  19. Second malaria vaccine R21/Matrix-M recommended by WHO
    A new vaccine, R21/Matrix-M has been recommended by the WHO for the prevention of malaria in children............
    #Malaria #Malariavaccine #Malarialparasite #Plasmodium #R21/MatrixM #Vaccine
    Umesh Prasad

    scientificeuropean.co.uk/medic

  20. Second malaria vaccine R21/Matrix-M recommended by WHO
    A new vaccine, R21/Matrix-M has been recommended by the WHO for the prevention of malaria in children............
    #Malaria #Malariavaccine #Malarialparasite #Plasmodium #R21/MatrixM #Vaccine
    Umesh Prasad

    scientificeuropean.co.uk/medic

  21. Second malaria vaccine R21/Matrix-M recommended by WHO
    A new vaccine, R21/Matrix-M has been recommended by the WHO for the prevention of malaria in children............
    #Malaria #Malariavaccine #Malarialparasite #Plasmodium #R21/MatrixM #Vaccine
    Umesh Prasad

    scientificeuropean.co.uk/medic

  22. Second malaria vaccine R21/Matrix-M recommended by WHO
    A new vaccine, R21/Matrix-M has been recommended by the WHO for the prevention of malaria in children............
    #Malaria #Malariavaccine #Malarialparasite #Plasmodium #R21/MatrixM #Vaccine
    Umesh Prasad

    scientificeuropean.co.uk/medic

  23. Second malaria vaccine R21/Matrix-M recommended by WHO
    A new vaccine, R21/Matrix-M has been recommended by the WHO for the prevention of malaria in children............
    #Malaria #Malariavaccine #Malarialparasite #Plasmodium #R21/MatrixM #Vaccine
    Umesh Prasad

    scientificeuropean.co.uk/medic

  24. 'The extrinsic incubation period (EIP), defined as the time it takes for malaria parasites in a mosquito to become infectious to a vertebrate host, is one of the most influential parameters for malaria transmission but remains poorly understood.'

    #Preprint #Malaria #Plasmodium

    biorxiv.org/content/10.1101/20

  25. Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.

    Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium

  26. Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.

    Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium

  27. Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.

    Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium

  28. Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.

    Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium

  29. Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.

    Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium

  30. "There are around 200 species of malaria parasite that can infect mammals, birds and reptiles. P. vivax is the most widely distributed form of malaria parasite in humans, and it is dominant in the Western Pacific and in highly populated areas of Latin America and Asia."

    #Plasmodium #Malaria #Infection #InfectiousDisease

    nature.com/articles/d41586-023

  31. Pour la première fois depuis 20 ans, 8 cas autochtones de #paludisme à #Plasmodium vivax ont été détectés en 2023 aux USA 🇺🇸 : 7 en Floride et 1 au Texas.

    vox.com/science/2023/6/23/2377

    Cette réémergence du paludisme serait-elle possible en France 🇫🇷 ?
    Aucune transmission autochtone de paludisme n’a été observée en France Métropolitaine depuis les années 1972… A l’exception d’un cas autochtone de paludisme à Plasmodium vivax en Corse en 2006. 1/4

  32. Malaria on a chip.

    'A functional, multi-organ, serum-free system was developed for the culture of P. falciparum in an attempt to establish innovative platforms for therapeutic drug development. It contains 4 human organ constructs including hepatocytes, splenocytes, endothelial cells, as well as recirculating red blood cells which allow for infection with the parasite. '

    #Malaria #Plasmodium

    nature.com/articles/s41598-023

  33. Five cases of locally acquired #malaria ( #Plasmodium vivax) in the 🇺🇸 (TX & FL). These are the first such cases recorded in 20 years.

    Quote: “…a changing #climate and shifting weather patterns increasingly drive #mosquito migration into new places worldwide, allowing malaria to settle in where it hasn’t before.”

    🦟 🦟🦟🦟🦟

    🔗 vox.com/science/2023/6/23/2377

    #ClimateChange #PublicHealth

  34. Malaria spreading in Texas and Florida; first US-based cases in two decades - Enlarge

    The Centers for Disease Control and Prevention is war... - arstechnica.com/?p=1950308 #plasmodium #outbreak #science #florida #malaria #p.vivax #health #texas #cdc

  35. My first preprint in Canada 🇨🇦 from the wonderful Wasmuth lab. My first preprint in a new field - parasitology!

    We used protein structures to identify molecular mimicry in Plasmodium falciparum.

    biorxiv.org/content/10.1101/20

    #parasitology #malaria #plasmodium #preprint #canada #parasites #bioinformatics