#plasmodium — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #plasmodium, aggregated by home.social.
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#Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second #rhoptry and is important for #erythrocyte invasion #PLOSBiology https://plos.io/3XQeiqY
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By Dear Hollow
Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.
Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal,” Duality offers the best of what you love about Defacement and quite a deal more.
Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.
The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.
For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.
Rating: 3.5/5.0
DR: N/A | Format Reviewed: STREAM
Label: Avantgarde Music
Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
Releases Worldwide: July 26th, 2024#2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis
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By Dear Hollow
Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.
Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal,” Duality offers the best of what you love about Defacement and quite a deal more.
Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.
The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.
For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.
Rating: 3.5/5.0
DR: N/A | Format Reviewed: STREAM
Label: Avantgarde Music
Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
Releases Worldwide: July 26th, 2024#2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis
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By Dear Hollow
Defacement has always been an apt but incomplete moniker for the act that professes it – best described by the International act’s1 2021 sophomore self-titled effort’s artwork. While the gore and violence of a face erased is enough for the blasting excess and macabre decadence of death metal, Defacement has always been content to meditate, to stare into the face – or lack thereof – in an undeniably unflinching but unquestionably thoughtful approach. Following two releases of dissonant and blackened death metal, Duality is a capitalization of what makes the act great, if not held back by old habits.
Featuring three members of Deathcrush, Defacement’s bread and butter relies on blazing riffs that straddle the line between dissonance and murk, outlined by insane drumming,2 and monstrous growls, as well as an unexpected love for industrial atmospheres. Duality features four tracks proper, punctuated by interludes, with the act’s most ambitious material yet. Comfortably fitting within the ranks of dissodeath and “esoteric death metal,” Duality offers the best of what you love about Defacement and quite a deal more.
Everything serves the riffs and the atmosphere aboard Duality, and both sides of the aptly titled album are showcased. The four main tracks, “Burden,” “Barrier,” “Scabulous,” and “Duality” alll encompass unique attacks of varying capacity, tied together by a tapestry of murk and dissonance. For instance, “Barrier” offers the most aggressive attack in its blazing riffs and war march drumming, while “Burden” showers listeners with a tastefully yearning melody between fluid movements between blackened tremolo and churning riffs. “Scabulous” is a foreshadowing in its more contemplative and arrhythmic lurching motion, preparation for the sixteen-minute closer. “Duality,” true to its name, delves into layers of flaying dissonance, rip-roaring solos, and head-crushing riffs, interspersed with moments of bittersweet melody. Because the album serves to be diverse in its approaches, its impenetrable murky mix courtesy of Gabriele Gramaglia (Cosmic Putrefaction, Vertebra Atlantis) and Simon Da Silva (Aversio Humanitatis) is a wonder to behold, as its esoteric layers create a swamp of sound aptly opaque for this style, but allowing free movement and appropriate shine to all its players.
The real downside to Duality is nearly exactly what downed its predecessor: interludes. While Defacement insists on creating a dark and murky environ with its death metal centerpieces, any momentum gained is quickly extinguished by unnecessary two-and-a-half-minute slurps of industrial noise and trip-hop beats. While they largely succeed in capitalizing upon the kind of place that Defacement hopes to evoke, they feel largely unnecessary and borderline derailing. This is why “Duality” is so effective as a closer, as its length provides adequate breadth and organicity for the act to seamlessly move between viciousness tinged with disharmony, slower menace, and climactic yearning melody – without interruptions or interludes. These aside, as competently as Defacement performs Duality, they nevertheless remain in limbo in capturing a unique palette – and instead evoke ghostly meanderings somewhere between Antediluvian, Plasmodium, and Ulcerate.
For all my complaints, Defacement nonetheless have created a work admirable for its sheer ambition in effectively sweeping listeners away to a place cold and otherworldly. With just enough melody to balance out the dissonance and murk, enough aggression to soar above pretense, and a stunning balance of the esoteric and punishing to get your head bobbing while admiring the bleakness, Defacement accomplishes what it sets out to do – creating their best offering thus far. However, with jarring industrial/trip-hop interludes killing momentum and a huge question mark regarding the act’s trademark beyond an amalgamation of dissodeath and blackened death’s respective echelons, Duality narrowly misses dealing a stunning blow. However, Defacement invites listeners to behold its gaping maw in blood-soaked reverie, and Duality offers its best incarnation yet.
Rating: 3.5/5.0
DR: N/A | Format Reviewed: STREAM
Label: Avantgarde Music
Websites: defacementofficial.bandcamp.com | facebook.com/officialdefacement
Releases Worldwide: July 26th, 2024#2024 #35 #Anguana #Antediluvian #AvantgardeMusic #AversioHumanitatis #BlackenedDeathMetal #ContinuumOfXul #CosmicPutrefaction #DeathMetal #Deathcrush #Defacement #DissonantDeathMetal #Duality #DutchMetal #EarthAndPillars #InternationalMetal #Jul24 #Plasmodium #Review #Reviews #Ulcerate #VertebraAtlantis
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'By employing a metabolic compartmentalization approach, we observed enhanced glycolysis and accumulation of the TCA-cycle derivative itaconate in splenic monocyte-derived dendritic cells from Plasmodium chabaudi (Pc)-infected mice.'
#Malaria #Plasmodium #HostPathogen #Metabolism #immunologyhttps://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00008-1
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Why do the #malaria parasite's #merozoite surface proteins #MSPs have exactly 2 deeply-diverged lineages? Genomic analysis of #Plasmodium DBLMSP & DBLMSP2 reveals the evolutionary explanation to this long-standing puzzle @bricoletc @ZaminIqbal #PLOSBiology https://plos.io/3TC8WOl
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Guten Morgen! Was war gestern schön was hat euch gefreut? Es sind die kleinen Dinge die zählen. Wenn ihr mögt, lasst eure #diekleinendinge hier.
Hier: Das Weißgelbe Netzpolster lebt auf vermoderndem Holz, auf Nadelstreu oder Blättern, wo es Bakterien jagt. Als Schleimpilz ist es kein Pilze sondern gehört zu den Amoebozoa. Schleimpilze sind also mit Pilzen in etwa so nahe verwandt wie wir mit Pflanzen. #schleimpilz #myxomycete #ceratiomyxafruticulosa #biodiversity #amoebozoa #plasmodium
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Pour la première fois depuis 20 ans, 8 cas autochtones de #paludisme à #Plasmodium vivax ont été détectés en 2023 aux USA 🇺🇸 : 7 en Floride et 1 au Texas.
Cette réémergence du paludisme serait-elle possible en France 🇫🇷 ?
Aucune transmission autochtone de paludisme n’a été observée en France Métropolitaine depuis les années 1972… A l’exception d’un cas autochtone de paludisme à Plasmodium vivax en Corse en 2006. 1/4 -
Our 2023 January issue reviews genomic #epidemiology of #malaria parasites, #seroprevalence of congenital #toxoplasmosis, animal models for human #babesiosis research, #systems biology of #tick-borne diseases, #histone #lactylation in #Plasmodium, & more. Vector of the Month: #Amblyomma #americanum.
https://www.cell.com/trends/parasitology/issue?pii=S1471-4922(22)X0002-0 -
#Introduction
I have a longstanding interest in identifying which genes the #malaria parasite needs to survive, and why. During my PhD I was involved in early genome-scale screens in #Plasmodium. Now, I'm delving into more detail on gene function at scale by building approaches for automated culture at #TheCrick.Since the pandemic I have also got into #GenomicEpidemiology in a big way. I created https://taxonium.org, a tool for exploring million-sequence trees, amongst other things.
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I am also interested in #Anopheles #mosquitoes that transmit #Plasmodium parasites which cause #malaria. I study #PopulationGenomics of these #vectors to find #CrypticSpecies and signals of #NaturalSelection which sometimes turns out to be not so natural (e.g. caused by #insecticides). Understanding patterns of #GeneticDiversity in these insects can help us better control them.
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Die Anopheles-Mücke ist winzig. Sie überträgt aber die gefährliche Tropenkrankheit Malaria. Eine weltweit zugelassene Impfung gibt es bislang nicht - dafür einige vielversprechende Ansätze.
Gibt es bald eine wirksame Malaria-Impfung? | DW | 20.08.2021
#Anopheles #Malaria #mRRTS #S #R21Matrix-M #UniTübingen #Tropenmedizin #Malaria-Impfung #Plasmodium #Parasit
