#inflammaging — Public Fediverse posts

Az "inflammaging" (gyulladásos öregedés) egy új tudományos fogalom, amely szerint az alacsony fokú, krónikus gyulladás az öregedési folyamatok egyik fő motorja. A mikrobiomnak kulcsszerepe van abban, hogy a gyulladás fennmarad-e. 🔥
#inflammaging #hosszúélet #mikrobiom #gyulladás #életmód
#aradiágnes #komplementeroktatóközpont #természetgyógyászoktatás #természetgyógyászat #egészség

#ORF:
"
Astronauten „altern“ im All schneller
"
"Im Weltraum ist der Körper extremem Stress ausgesetzt. Grund dafür ist nicht nur die ungewohnte Umgebung, sondern auch die fehlende Schwerkraft, an die jeder Mensch auf der Erde angepasst ist. Astronauten reagieren darauf, indem ihr Immunsystem „altert“"

https://science.orf.at/stories/3231024/

9.9.2025

#Alterung #Astronautik #Gehirn #Immunsystem #Inflammaging #ISS #LMU #Raumfahrt #Raumstation #SpaceFlight #Weltraummedizin

#inflammaging is not universal: In a comparison of (1) two cohorts from industrialized countries with (2) two cohorts of more rural lifestyles, only the first group showed an increase of inflammation markers (& corresponding diseases) with age. #inflammation #ageing
https://www.nature.com/articles/s43587-025-00888-0

Arginase II is an enzyme that accelerates #aging of the #heart, though curiously it doesn't show up in the main heart cells (cardiomyocytes). Turns out to be another case of #inflammaging. Experiments in mice. https://elifesciences.org/reviewed-preprints/94794

How to Combat #Inflammaging, the #Aging Side Effect No One Talks About

https://getpocket.com/explore/item/how-to-combat-inflammaging-the-aging-side-effect-no-one-talks-about

Human aging is assoc. with inflammation and intestinal barrier dysfunction. One might assume that barrier permeability would spark increased inflammation. This (and prev.) work suggests the opposite—that #inflammaging, driven by #monocytes and #macrophages appear to *cause* the barrier dysfunction!

Effect of #gut #microbiota-mediated tryptophan metabolism on inflammaging in frailty and sarcopenia

"...Trp metabolism, and #inflammaging in age-related #frailty and #sarcopenia may be a worthwhile #research direction to help promote healthy #aging..."

#Health #Ageing #Inflammation #Science

https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glae044/7608682?redirectedFrom=fulltext

Now Aki Minoda, Radboud University, The Netherlands
https://www.ru.nl/en/departments/radboud-institute-for-molecular-life-sciences-fnwi-deel/cell-biology
talking about
the Mukin Mouse Ageing Atlas
(mukin means #germ-free in Japanese)

#SingleCell from tissues sampled at 2 and 19 months in mice, then #omics including #lipidomics

Looking at influence of #microbiota on changes in #aging e.g. expansion of #immune cell types, aka #inflammaging

#CSSingleCells23