#cssinglecells23 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cssinglecells23, aggregated by home.social.
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Lacramioara Bintu of Stanford
https://bintulab.com/#SingleCell dynamics of gene silencing, epigenetic memory, and #chromatin organization
silencing & reactivation of expression all-or-none via #histonemethylation
3 states: active, reversible silent, irreversible silent
chromatin regulators move proportion of cells in OFF state
KRAB can "remember" duration of signal, makes heterochromatin, which can spread spatially
Want to see chromatin state in single cells
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