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#cssinglecells23 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cssinglecells23, aggregated by home.social.

  1. Last session of the conference! Continuing theme of "Cell identity in situ"

    Parker Côté, DFCI
    in Li Lab
    ki.mit.edu/people/clinical-inv

    The #transcriptional dynamics of human #hematopoiesis at #SingleCell resolution

    do #StemCells and #ProgenitorCells in #hematopoietic system (#HSPC) change with age?

    HSPCs exist on a continuum of cell types

    They identified #GeneExpression programs active in uncommitted cells, looking across human development (fetal to aged)

    biorxiv.org/content/10.1101/20

    #CSSingleCells23

  2. Sophie Dumont at UCSF
    dumontlab.ucsf.edu/

    #Chromosome size alters #kinetochore attachment stability and alignment order in mammalian #mitosis

    Lab interested in #SelfOrganization and emergent mechanics across scales.... "biological structures build themselves" using only local cues they get global information. mitotic spindle a great example

    kinetochores attach, sense tension, can make mistakes which are corrected. how does this work when chromosomes vary in size?

    #CSSingleCells23

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