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#reprogramming — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #reprogramming, aggregated by home.social.

  1. Fasting 🍥 14h_ after "la purge" - withs magnesium chloor ⚗️ in the morning a juice 🧃 with kale apple & lemon will get just soon in a phase of autophagy where proteins stuck to your intestin get recycled. Protosynthesis. 🦠
    #reprogramming#biocomputer
    #transhackfeminist

  2. If you are joining #GSCN don't miss the talk by Dr. Angeliki Spathopoulou on novel #stemcell regulators for #iPSC #reprogramming on Thursday morning (T26) or any of our lab's posters!

    #science

  3. 4.) Is there currently any evidence of efficacy of any of the proposed "#anti-aging drugs" and interventions in human aging? E.g. #rapamycin, #metformin #resveratrol but also #reprogramming, #rejuvenation, #caloric restriction and others? In other words, is there a shortcut to health and eternal life? Spoiler: you might not like the answer... Moreover, some of these might even have negative effects on other health-beneficial interventions, e.g. the potential dampening of exercise training adaptation by metformin, resveratrol or rapamycin.

    5.) We discuss all of the known factors for which solid data and proof for an impact on human health, the aging process, #morbidity (risk for a disease), #mortality (risk of premature death) and life expectancy exist. The good news: only around 20% (or even as low as 10%) of our aging trajectory is determined by our genes – this means that to a large majority, we can influence this ourselves! Some can be done on the individual level, first and foremost by physical activity, but also #sleep, #nutrition, #stress, social interactions and more. Others will have to be addressed on the societal/political level, e.g. #socioeconomic disparities or access to quality (and affordable) health care. Lastly, there are factors such as anthropogenic #climatechange or #pollution (e.g. air pollution or #microplastics) that we have to solve on a global scale.

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  4. 4.) Is there currently any evidence of efficacy of any of the proposed "#anti-aging drugs" and interventions in human aging? E.g. #rapamycin, #metformin #resveratrol but also #reprogramming, #rejuvenation, #caloric restriction and others? In other words, is there a shortcut to health and eternal life? Spoiler: you might not like the answer... Moreover, some of these might even have negative effects on other health-beneficial interventions, e.g. the potential dampening of exercise training adaptation by metformin, resveratrol or rapamycin.

    5.) We discuss all of the known factors for which solid data and proof for an impact on human health, the aging process, #morbidity (risk for a disease), #mortality (risk of premature death) and life expectancy exist. The good news: only around 20% (or even as low as 10%) of our aging trajectory is determined by our genes – this means that to a large majority, we can influence this ourselves! Some can be done on the individual level, first and foremost by physical activity, but also #sleep, #nutrition, #stress, social interactions and more. Others will have to be addressed on the societal/political level, e.g. #socioeconomic disparities or access to quality (and affordable) health care. Lastly, there are factors such as anthropogenic #climatechange or #pollution (e.g. air pollution or #microplastics) that we have to solve on a global scale.

    2/4

  5. Ascl1 modified at 6 sites to be phosphorylation-resistant leads to in vivo reprogramming of Astrocytes into PV+ fast-spiking neurons. (Also this is enhanced by co-expressing Bcl2).

    Reprogramming astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site–deficient Ascl1
    Marichal et al., Science Advances 2024
    doi.org/10.1126/sciadv.adl5935

    #neuroscience #interneurons #reprogramming

  6. Никто не ждал, никто не просил, никто не хотел...
    Но я всё равно вернулся с новым видиком про железо. Да и не просто с железом, а с самодостаточным девайсом времен Pentium 4.
    478 сокет не только вечен, он ещё и вездесущ.

    youtu.be/K7S_8W5iDCA?si=A9L-Ws

    #pentium4 #retrocomputing #reprogramming #hwh

  7. Does #circadian gene expression affect #reprogramming of differentiated cells? Study shows that contaminating #macrophages in #fibroblast culture can inhibit reprogramming to #neurons & #iPSCs, controlled by the clock gene Per1 #PLOSBiology plos.io/47YBh6d

  8. The last guest in #reprogramming #podcast series is #EyalWeizman. He is a founder of Forensic Architecture, where he helped develop a methodology – counter forensics – for 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝗻𝗴 𝗰𝗮𝘀𝗲𝘀 𝗼𝗳 𝗵𝘂𝗺𝗮𝗻 𝗿𝗶𝗴𝗵𝘁𝘀 𝘃𝗶𝗼𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗿𝗼𝘂𝗻𝗱 𝘁𝗵𝗲 𝘄𝗼𝗿𝗹𝗱 to provide new evidence against official narratives in international human rights courts.

    Listen in to the conversation he had with #MartaPeirano at aksioma.org/podcast/reprogramm

    #aksioma #tacticspractice #kons

  9. IGF2BP2-meidated m6A modification of CSF2 reprograms MSC to promote gastric cancer progression. doi.org/10.1038/s41419-023-061

  10. In a media landscape dominated by social media, we want everything to go viral, but small groups of well-organised people can have a larger impact than millions protesting in the streets or online.

    In the 7th #reprogramming podcast we talk about #community. #MartaPeirano’s guest is #AstraTaylor, an international filmmaker, writer and political organiser.

    👂 Listen at: aksioma.org/podcast/reprogramm

    #aksioma #tacticspractice #podcast

  11. What happens when we purchase an item on Amazon? Who owns the profile images posted on dating apps? How many trees are needed to absorb the amount of CO2 generated by the global visits to Google every second?

    Through the artistic outputs of her findings, #JoanaMoll transforms these revelations into tangible concepts fostering awareness in the collective consciousness of the footprint caused by our use of the Cloud.

    aksioma.org/podcast

    #tacticspractice #reprogramming #MartaPeirano #konS

  12. Far from being immaterial, AI is made of flesh, sweat and fossil fuels, and is not neutral. Also, AI stands as one of the most concentrated industries of the world.

    👂 Tune in to the new #reprogramming episode. Listen at: aksioma.org/podcast

    #MartaPeirano hosts a leading scholar on the social implications of artificial intelligence #KateCrawford; and some special guests with questions related to the topic.

    #aksioma #tacticspractice #konS

  13. New podcast!

    #MartaPeirano talks with #AnabJain, whose work transports people into the future.

    aksioma.org/podcast

    Jain is a designer, a filmmaker & co-founder of #Superflux, a speculative design studio that explores the intersections of climate crisis, technology and more-than-human politics. In this episode she gives the listeners an emotional vade mecum to imagine and possibly shape the future [...]

    #aksioma #tacticspractice #kons #reprogramming

  14. Natural killer #NKcell #reprogramming into mature T cells is actively inhibited by the #NuRD complex and #BCL11B-mediated regulation of #H3K27 acetylation - which also inhibit #OPA1-dependent #mitochondrial fusion in #Tcells
    Peng Li and collaborators
    embopress.org/doi/full/10.1525

  15. Second half of the "variation and information" session #CSSingleCells23
    led off by Sam Morris of WashU
    morrislab.wustl.edu/

    Multi-omic lineage tracing: insights into reprogramming cell identity

    her piece in *Development*, "The evolving concept of cell identity in the single cell era"

    working on "induced hepatocytes", start with fibroblasts, via "induced endoderm progenitors"

    new work on #adipocytes
    biorxiv.org/content/10.1101/20

    #reprogramming
    #StemCells
    #CellIdentity
    #CellFate

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  16. Proud of publishing my first @PeerCommunityJournal paper after recommendation from PCI MathCompBiol 😃

    I present a logical modeling and resolution method for #reprogramming the fixed points and minimal trap spaces of #BooleanNetworks, which accounts for the creation of new attractors:
    peercommunityjournal.org/artic