#cellfate — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cellfate, aggregated by home.social.
-
Second half of the "variation and information" session #CSSingleCells23
led off by Sam Morris of WashU
http://morrislab.wustl.edu/Multi-omic lineage tracing: insights into reprogramming cell identity
her piece in *Development*, "The evolving concept of cell identity in the single cell era"
working on "induced hepatocytes", start with fibroblasts, via "induced endoderm progenitors"
new work on #adipocytes
https://www.biorxiv.org/content/10.1101/2023.06.01.543318v1#reprogramming
#StemCells
#CellIdentity
#CellFate1/2
-
Yogesh Goyal at Northwestern Feinberg
https://www.goyallab.org/Topic:
Tracing rare cell plasticity and diverse fate decisions in single cancer cellsBegins with reference to (and pic of) Monod's *Chance and Necessity*
#CellFate
#SingleCell
#CSSingleCells23Emphasizing non-genetic differences between cells, something we can only see at single-cell resolution
Refers to Luria & Delbruck 1943 about bacterial resistance (to phage), relevant to cancer resistance to therapy (selected)
1/2
-
A healing #wound is a microcosm of many cell states found during #organogenesis. In addition to dead and dying cells, one may find proliferating cells, migrating cells, and cells that are differentiating or switching fate. How is this multitude of cell states, often mutually exclusive, established and maintained for successful repair and #regeneration?
--from Primer by Tin Tin Su in @PLOSBiology
#developmentalbiology
#differentiation
#cellfatehttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002155
-
In EMBO Journal issue 3:
Host #mucins negotiate peace with #toxigenic #Vibrio
Cytosolic #stressgranules relieve nuclear #ubiquitin-#proteasome system
#Smoothened #cholesterylation and ER exit links in #Hedgehog signaling
Developmental #cellfate decision control by #chromatin reader #TRIM33
Cover by Kimon Lemonides, Helen Walden et al -
How does #chromatin reader #TRIM33 control #developmental #cellfate decisions?
Qiaoran Xi Lab at Tsinghua University finds that its embryonic #stemcell-specific recruitment into #PML #nuclearbodies regulates #Lefty1/2 expression upon #Nodal signaling
-
Single-cell imaging during #adipocyte differentiation reveals a control principle whereby #progenitor cells induced to differentiate can reach the desired distinct differentiated #CellFate despite the many alternative fates en route @TeruelLab #PLOSBiology https://plos.io/3Y38VTu
-
Single-cell imaging during #adipocyte differentiation reveals a control principle whereby #progenitor cells induced to differentiate can reach the desired distinct differentiated #CellFate despite the many alternative fates en route @TeruelLab #PLOSBiology https://plos.io/3Y38VTu
-
Single-cell imaging during #adipocyte differentiation reveals a control principle whereby #progenitor cells induced to differentiate can reach the desired distinct differentiated #CellFate despite the many alternative fates en route @TeruelLab #PLOSBiology https://plos.io/3Y38VTu
-
With #TwitterMeltdown continues, our lab is looking for a RA. Please DM or [email protected]
We have one project with exciting data open for you
#HKU #CellFate #Epigenome #Myeloid #Development -
CW: Combinatorial interpretation of BMP and WNT allows BMP to act as a morphogen in time but not in concentration.
"[...] varying the duration of #BMP #signaling leads to either pluripotent, mesodermal, and extraembryonic states, while varying the concentration does not cause efficient mesodermal differentiation at any dose [...] appropriately timed pulse of BMP induces #hPSCs to a mesodermal fate more efficiently that sustained signaling at any concentration. [...] this effect is due to a combinatorial interpretation of the applied BMP signal and induced endogenous #Wnt signaling."
https://www.biorxiv.org/content/10.1101/2022.11.11.516212v1?rss=1
#DevBio #CellFate #GermLayers #morphogens #Differentiation