#epigenome — Public Fediverse posts

The #Epigenome is a dynamic layer of chemical tags and structural proteins attached to DNA. It acts as the body's software, directing the genome (hardware) on which genes to switch on or off, and when.

It dictates cell identity, allowing identical DNA to become diverse cells like a neuron or muscle cell.

https://knowledgezone.co.in/kbits/6a4c85a83780278e7229f925

#Interstellar #Passover : Medium

#CRISPR’s next #Act: the companies editing the #Epigenome to treat #Disease : Nature

#Astrophysicists #Puzzle Over #Webb’s New #Universe : Quanta Mag

Latest #KnowledgeLinks

https://knowledgezone.co.in/resources/bookmarks

"Cells that store fat, or adipocytes, and immune cells, such as macrophages, that live in fat tissue can remember weight long after it’s lost. And scientists suggest obesity causes lasting changes to those cells that make it easier to revert the body to a state of obesity, even after significant weight loss."

https://www.scientificamerican.com/article/cells-in-the-body-remember-obesity-heres-what-that-means-for-weight-loss/

#Obeisty #Health #Cells #Metabolism #Epigenome

Pipeline release! nf-core/methylseq v4.2.0 - Tapus Maximus!
Methylation (Bisulfite-Sequencing) analysis pipeline using Bismark or bwa-meth MethylDackel
Please see the changelog: https://github.com/nf-core/methylseq/releases/tag/4.2.0

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/methylseq v4.1.0 - Burrows Stardust!

Please see the changelog: https://github.com/nf-core/methylseq/releases/tag/4.1.0

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/methylseq v4.0.0 - Wallace Chrysalis!

Please see the changelog: https://github.com/nf-core/methylseq/releases/tag/4.0.0

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

DATE: February 24, 2025 at 07:00AM
SOURCE: BioWorld MedTech

Direct article link at end of text block below.

Evo 2 AI allows #genome and #epigenome modeling of all life domains

https://t.co/kdzNS6UJcA

#medtech

Here are any URLs found in the article text:

https://t.co/kdzNS6UJcA

#medtech

Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .

-------------------------------------------------

Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
.
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
.
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
.
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE:
http://subscribe-article-digests.clinicians-exchange.org
.
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
.
It's primitive... but it works... mostly...
.
-------------------------------------------------

#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech

DATE: February 21, 2025 at 05:00PM
SOURCE: BioWorld MedTech

Direct article link at end of text block below.

Evo 2 AI allows #genome and #epigenome modeling of all life domains

https://t.co/kdzNS6Vh28

#medtech

Here are any URLs found in the article text:

https://t.co/kdzNS6Vh28

#medtech

Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .

-------------------------------------------------

Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
.
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
.
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
.
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE:
http://subscribe-article-digests.clinicians-exchange.org
.
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
.
It's primitive... but it works... mostly...
.
-------------------------------------------------

#healthcare #healthtech #healthcaretech #healthtechnology #medgadget #medicine #doctor #hospital #medtech

Otro artículo sobre ambiente, estilo de vida e influencia en la fertilidad masculina a través del epigenoma. Desde la capacidad fértil del espermatozoide hasta la descendencia. https://buff.ly/3E6NhIF #bianorbiotech #epigenome #environment #lifestyle #MaleFertility #Embryo #OffspringHealth

How do lifestyle and environme...

Pipeline release! nf-core/methylseq v3.0.0 🎉

* Modular Bismark & Bwameth Subworkflows
* GPU Support for Bwameth
* BS-Seq Primer & Updated Documentation
* Run Qualimap & Preseq Options
* Reorganized Configuration Files

See the changelog for details: https://github.com/nf-core/methylseq/releases/tag/3.0.0

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/methylseq v2.7.1 - Shattners Bassoon!

Please see the changelog: https://github.com/nf-core/methylseq/releases/tag/2.7.1

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/methylseq v2.7.0 - Chubby Unicorn!

Please see the changelog: https://github.com/nf-core/methylseq/releases/tag/2.7.0

#bisulfitesequencing #dnamethylation #emseq #epigenome #epigenomics #methylseq #pbat #rrbs #nfcore #openscience #nextflow #bioinformatics

Team develops an #epigenome editing toolkit to dissect the mechanisms of #gene_regulation.

https://phys.org/news/2024-05-team-epigenome-toolkit-mechanisms-gene.html

#Circadian stress response provides an insight into metabolic #communication via the #mitochondrial #epigenome.

https://phys.org/news/2023-12-circadian-stress-response-insight-metabolic.html

Using #DNAsequencing to show how marine worms adapt to #DeepSea conditions https://phys.org/news/2023-10-dna-sequencing-marine-worms-deep-sea.html

Third-Generation #Sequencing Reveals the Adaptive Role of the #Epigenome in Three Deep-Sea #Polychaetes: Maeva Perez et al. https://academic.oup.com/mbe/article/40/8/msad172/7231443

"#epigenetic regulation by #DNAmethylation could be an adaptive mechanism that counteracts the effects of hydrostatic pressure at the bottom of the #ocean"

#Epigenome editing is an emerging technology used to regulate #gene function by controlling epigenetic states at specific locations on the #genome. This method is distinct from traditional #genetic editing, which involves permanently altering the #DNA sequence.
#Biology #sflorg
https://www.sflorg.com/2023/11/bio11082301.html

Using #DNAsequencing to show how marine #worms adapt to deep-sea conditions https://phys.org/news/2023-10-dna-sequencing-marine-worms-deep-sea.html

Third-Generation #Sequencing Reveals the Adaptive Role of the #Epigenome in Three #DeepSea #Polychaetes: Maeva Perez et al. https://academic.oup.com/mbe/article/40/8/msad172/7231443

"#Methylation is an #epigenetic process that chemically modifies some of DNA bases. It plays a role in environmental acclimatization, making organisms living in habitats where conditions are unpredictable more resilient to environmental changes"

#InterPlanetary 🪐 #SpaceTravel might get easier

Mice’s 🐁 organs and tissues resumed a #youthful state.
The therapy “set in motion an epigenetic program that led cells to restore the #epigenetic information they had when they were #young. It’s a permanent #reset.” https://hms.harvard.edu/news/loss-epigenetic-information-can-drive-aging-restoration-can-reverse

#epigenome #epigenetics #ForeverYoung #MarsTrilogy #SciFi

Last speaker of the day is the keynote:
Xiaowei Zhuang
Harvard University
https://zhuang.harvard.edu/pi.html

Spatially resolved #SingleCell genomics and cell atlas of the #brain

Explaining MERFISH, now I get it 🤓

Now have adapted to #epigenome: https://pubmed.ncbi.nlm.nih.gov/36272405/

and to thick tissue:
https://www.biorxiv.org/content/10.1101/2023.07.21.550124v1

Now discussing this epic MERFISH atlas of the whole mouse brain
https://www.biorxiv.org/content/10.1101/2023.03.06.531348v1

use imputation to infer cell-cell interactions (several hundred cell types), cool

#CSSingleCells23

Postdoctoral fellow @robertobellell1

Come join us in #London as a #postdoc to unveil new mechanisms of #genome and #epigenome stability at the replication fork.

https://jobrxiv.org/job/barts-cancer-institute-27778-postdoctoral-fellow/?feed_id=43050

#ScienceJobs #job
London #UnitedKingdomUK #PostdoctoralFello...
https://jobrxiv.org/job/barts-cancer-institute-27778-postdoctoral-fellow/?feed_id=43050

Read this study from the labs of Zachary Smith and Alex Meissner on the of the interplay between #Polycomb silencing and #DNAmethylation to maintain gene silencing in extra-embryonic tissues:

Dynamic antagonism between key repressive pathways maintains the placental #epigenome.

Nat Cell Biol (2023). https://doi.org/10.1038/s41556-023-01114-y

🙌 Our scientist Alexander Meissner #MeissnerLab receives an #ERC Advanced Grant! He will use it to decipher the cancer #epigenome with clues from #DevelopmentalBiology

👉https://www.molgen.mpg.de/4613519/

#ERCAdG @ERC_Research

In the most episode we caught up with Paul Shiels from the University of Glasgow to talk about his work on the effects of environmental cues on the #epigenome and #longevity. #epigenetics #chromatin #aging

Listen here: https://activemotif.com/podcasts#paul-shiels

In this episode we caught up with Paul Shiels from the University of Glasgow to talk about his work on the effects of environmental cues on the #epigenome and #longevity. #epigenetics #chromatin @epigenetics

Listen here: https://activemotif.com/podcasts#paul-shiels

Being able to control not just what genes exist in a genome, but also how those genes are expressed is critical to biological research, including agricultural disease resistance research.

UCLA and Danforth Center scientists have used an older method of DNA manipulation (zinc finger nucleases) to block a cassava gene exploited by the cassava bacterial blight pathogen.

#Agriculture #ZFN #Genomics #Biology #Scicomm #Cassava #Epigenetics #Epigenome #Methylation

https://www.nature.com/articles/s41467-022-35675-7

#Epigenome Programming by #H3.3K27M Mutation Creates a Dependence of #Pediatric #Glioma on #SMARCA4 @CD_AACR https://aacrjournals.org/cancerdiscovery/article-abstract/12/12/2906/711163/Epigenome-Programming-by-H3-3K27M-Mutation-Creates/

🧬🌿As part of our recent special issue, Zhang et al. discuss the past, present, and future of #DNA #demethylation in plants--from the discovery of #ROS1 in #Arabidopsis to #epigenome editing for #crop breeding and #GeneTherapy🔓⬇️ #PlantScience #PlantBiology
https://doi.org/10.1111/jipb.13423
@wileyplantsci
#PlantSci

With #TwitterMeltdown continues, our lab is looking for a RA. Please DM or [email protected]
We have one project with exciting data open for you
#HKU #CellFate #Epigenome #Myeloid #Development